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The map label for this gene is xseA

Identifier: 170754662

GI number: 170754662

Start: 2013605

End: 2014816

Strand: Reverse

Name: xseA

Synonym: CLD_2752

Alternate gene names: 170754662

Gene position: 2014816-2013605 (Counterclockwise)

Preceding gene: 170757090

Following gene: 170755467

Centisome position: 50.9

GC content: 27.06

Gene sequence:

>1212_bases
ATGCATATTAAAACTCTTACAGTTTCTCAGTTAAATAGATATGTAAAAAATACCTTAGATGCTGATTTTATATTAAATAA
TGCTTCCGTAAAGGGTGAAATATCAAATCTTAAAATTCACAGTAGCGGCCATATTTATTTTTCCTTAAAGGATGGAGGAA
GTAAAATAAATTGTGTAATGTTTAAAAGCTATGCATATAATTTAAAGTTTGCACTAGAAAATGGTATGGACGTAGTAGCT
CTAGGAAATGTATCTGTATATGAGAAGGAAGGCTCTTATCAATTATATGTTAAAGATATAAAAAGAGAGGGCATAGGAGA
CCTTTATGTAGCCTTTGAAAAGTTAAAAGAAAAACTTAAAGAAGAAGGACTTTTTGATGATGTACATAAAAAAGAAATAC
CTAAATTTTCTAAAAAAGTAGGGGTAATAACCTCACCTACAGGAGCAGTCCTAAAAGATATCATAAATGTAACTAAAAGA
AGAAATAAAGGGATAGAACTATTAATATATCCTGCCCTAGTACAAGGAACAAATGCTAGTAGAACTCTTATAGAGGGTAT
AAAAATATTAAATAAAGTTGAAGATGTAGATATAATAATATTAGCTCGTGGAGGAGGATCTATAGAAGAATTATGGGCTT
TTAATAATGAAGAGTTAGCTTATGCAGTGTATAATTCTAAAAAGCCTATAATAACCGGAGTAGGTCATGAAACGGATTTT
ACTATTGTAGACTTTGTAAGTGATAGAAGAGCACCTACGCCCTCTGCGGCTGCAGAAATAGCTGTTTTTGATAGAGAAGT
TCTAATAAACGAGATTTTAAATTATAAGTATAATATAAAAAATTCTATGGAAAATATAATAAAAGAAAAAAGAAATTATT
TAAATTTATACAAACAGAAAATAGAAGCTAACAGTCCTACTAATATAATAGTAAATGAATATAAAAATATAGATAATTTA
AAAGAATTATTAAATATGAAAATAGAAGGTAAATTAAATAAAGAAAAAAACAATCTATCCAGACTATCCTCTTTACTAGA
AGCGCATAATCCACTAAATGTATTAAAAAAAGGATATACGTTAATAGAGGATGAAGGGAATAATTTAATAACAGAAAAAG
AAGCCTTAAAGAAATTAAATAAAATAAACATAATCTTTAAAGATGGTAGGGCAAAATTATCTATTGAGTATATAGAAGAA
TTTTTAAAATAA

Upstream 100 bases:

>100_bases
ATAAATGGTGTTTTAGGTAAAATGATTTAAAATTAATAAATATTTAAAAAGTGAAGAGCTTAGCTTTTCACTTTTAATAT
TAATAAAAAGGAAGATGTTT

Downstream 100 bases:

>100_bases
TTCTTTAAGAGCTACACAAATATCATAGTAAACTTTATATTTGTGTTATGGTAGTTTATATTTAATAATTTAGAAATTAT
TAAATTGTAAATAATAAACT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVMFKSYAYNLKFALENGMDVVA
LGNVSVYEKEGSYQLYVKDIKREGIGDLYVAFEKLKEKLKEEGLFDDVHKKEIPKFSKKVGVITSPTGAVLKDIINVTKR
RNKGIELLIYPALVQGTNASRTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRNYLNLYKQKIEANSPTNIIVNEYKNIDNL
KELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYTLIEDEGNNLITEKEALKKLNKINIIFKDGRAKLSIEYIEE
FLK

Sequences:

>Translated_403_residues
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVMFKSYAYNLKFALENGMDVVA
LGNVSVYEKEGSYQLYVKDIKREGIGDLYVAFEKLKEKLKEEGLFDDVHKKEIPKFSKKVGVITSPTGAVLKDIINVTKR
RNKGIELLIYPALVQGTNASRTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRNYLNLYKQKIEANSPTNIIVNEYKNIDNL
KELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYTLIEDEGNNLITEKEALKKLNKINIIFKDGRAKLSIEYIEE
FLK
>Mature_403_residues
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVMFKSYAYNLKFALENGMDVVA
LGNVSVYEKEGSYQLYVKDIKREGIGDLYVAFEKLKEKLKEEGLFDDVHKKEIPKFSKKVGVITSPTGAVLKDIINVTKR
RNKGIELLIYPALVQGTNASRTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRNYLNLYKQKIEANSPTNIIVNEYKNIDNL
KELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYTLIEDEGNNLITEKEALKKLNKINIIFKDGRAKLSIEYIEE
FLK

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=359, Percent_Identity=35.3760445682451, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_CLOBK (B1IMN8)

Other databases:

- EMBL:   CP000939
- RefSeq:   YP_001781436.1
- GeneID:   6149424
- GenomeReviews:   CP000939_GR
- KEGG:   cbb:CLD_2752
- HOGENOM:   HBG634411
- OMA:   THQTAYL
- ProtClustDB:   PRK00286
- BioCyc:   CBOT498213:CLD_2752-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 45657; Mature: 45657

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVM
CCEEEEEHHHHHHHHHHCCCHHEEEECCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEE
FKSYAYNLKFALENGMDVVALGNVSVYEKEGSYQLYVKDIKREGIGDLYVAFEKLKEKLK
EEEEEEEEEEEECCCCEEEEECCEEEEECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHH
EEGLFDDVHKKEIPKFSKKVGVITSPTGAVLKDIINVTKRRNKGIELLIYPALVQGTNAS
HCCCCCHHHHHHCCCHHHHCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCH
RTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCE
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRNYLNLYKQK
EEEEEHHCCCCCCCCHHHEEHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHH
IEANSPTNIIVNEYKNIDNLKELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYT
HCCCCCCEEEEHHHCCHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
LIEDEGNNLITEKEALKKLNKINIIFKDGRAKLSIEYIEEFLK
EEECCCCCEECHHHHHHHHHHEEEEEECCCCEEEHHHHHHHHC
>Mature Secondary Structure
MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVM
CCEEEEEHHHHHHHHHHCCCHHEEEECCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEE
FKSYAYNLKFALENGMDVVALGNVSVYEKEGSYQLYVKDIKREGIGDLYVAFEKLKEKLK
EEEEEEEEEEEECCCCEEEEECCEEEEECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHH
EEGLFDDVHKKEIPKFSKKVGVITSPTGAVLKDIINVTKRRNKGIELLIYPALVQGTNAS
HCCCCCHHHHHHCCCHHHHCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCH
RTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDF
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCE
TIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNSMENIIKEKRNYLNLYKQK
EEEEEHHCCCCCCCCHHHEEHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHH
IEANSPTNIIVNEYKNIDNLKELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYT
HCCCCCCEEEEHHHCCHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
LIEDEGNNLITEKEALKKLNKINIIFKDGRAKLSIEYIEEFLK
EEECCCCCEECHHHHHHHHHHEEEEEECCCCEEEHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA