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The map label for this gene is aroE

Identifier: 170754603

GI number: 170754603

Start: 2666170

End: 2666946

Strand: Reverse

Name: aroE

Synonym: CLD_2096

Alternate gene names: 170754603

Gene position: 2666946-2666170 (Counterclockwise)

Preceding gene: 170755460

Following gene: 170756990

Centisome position: 67.38

GC content: 24.58

Gene sequence:

>777_bases
ATGTATACAACAGGTTTAATAGGTAAAAATATTAATTATTCAGAGTCACCAGAAATACACAATAATTATTACAAAAAAAA
TAATATACCATTCTTTTATAAAATATTTAATTTAAAGCAGGATCAAATTGATGATTTTATAAAGAACTTACATAAGAATA
ATATAAAAGGATTTAATGTTACTATTCCATATAAAGAAACAATATTACAATATTTAAATGATATAGTATATCCAGCAGAT
AAGATAGAAGCAGTGAATACTGTAGCAGTACAGGAAGATAAACTAATAGGGTATAATACAGACTATATAGGATTTATAAA
AAGTTTACAATATTACAATATACAGGTTAAAAATTTTAAGTGTCTCATTATAGGATCAGGTGGAAGTGCCAAGTGTATAT
ATTATGCATTAAAAGAATTAAATGCAAGAGATATATGTATAGTTTCTAGAAATCCTGAGAAAGCAAGACTAAAATTTGAA
AAAAAAGTTAAAATATTAAATATTAAAGACGAAAATAAATTAGATAGATATGATTTAATTATAAACTGTACACCCATAGG
CGGACCTAATTTTAAAGAACAAAAACCTATAGAACTTAAAGAGATCAAAAAAAATTGTGTGGTTTATGATTTAAATTATA
CTCCTAAAAGGTCTAAATTATTAAAAGAAGCTAAAGAAAATGGAGCATTTATTATAAATGGAGAAAAAATGCTCATTTTT
CAGGCCTATAGTGCTATAGGTCTTTGGTGCTTAAATGGTATTAAAGGAGGACGATAA

Upstream 100 bases:

>100_bases
GGTGATTCTTAATTCTTTTGTTTTATTTTTTATTTATTTTATGGTAGGAGATTCTTTACAGAATATTTATAATCGTTATA
ATATAAGCAGGAGGGTTTAA

Downstream 100 bases:

>100_bases
ATTGAAACAATTAAAAGAATTATTAGAAAAAACTATTAACTTTGGTGCTTCAGATTTACATTTATCCGTAGGAGTAGAAC
CAACTATAAGAATAAATGGA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MYTTGLIGKNINYSESPEIHNNYYKKNNIPFFYKIFNLKQDQIDDFIKNLHKNNIKGFNVTIPYKETILQYLNDIVYPAD
KIEAVNTVAVQEDKLIGYNTDYIGFIKSLQYYNIQVKNFKCLIIGSGGSAKCIYYALKELNARDICIVSRNPEKARLKFE
KKVKILNIKDENKLDRYDLIINCTPIGGPNFKEQKPIELKEIKKNCVVYDLNYTPKRSKLLKEAKENGAFIINGEKMLIF
QAYSAIGLWCLNGIKGGR

Sequences:

>Translated_258_residues
MYTTGLIGKNINYSESPEIHNNYYKKNNIPFFYKIFNLKQDQIDDFIKNLHKNNIKGFNVTIPYKETILQYLNDIVYPAD
KIEAVNTVAVQEDKLIGYNTDYIGFIKSLQYYNIQVKNFKCLIIGSGGSAKCIYYALKELNARDICIVSRNPEKARLKFE
KKVKILNIKDENKLDRYDLIINCTPIGGPNFKEQKPIELKEIKKNCVVYDLNYTPKRSKLLKEAKENGAFIINGEKMLIF
QAYSAIGLWCLNGIKGGR
>Mature_258_residues
MYTTGLIGKNINYSESPEIHNNYYKKNNIPFFYKIFNLKQDQIDDFIKNLHKNNIKGFNVTIPYKETILQYLNDIVYPAD
KIEAVNTVAVQEDKLIGYNTDYIGFIKSLQYYNIQVKNFKCLIIGSGGSAKCIYYALKELNARDICIVSRNPEKARLKFE
KKVKILNIKDENKLDRYDLIINCTPIGGPNFKEQKPIELKEIKKNCVVYDLNYTPKRSKLLKEAKENGAFIINGEKMLIF
QAYSAIGLWCLNGIKGGR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=260, Percent_Identity=25, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789675, Length=259, Percent_Identity=30.8880308880309, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=273, Percent_Identity=26.3736263736264, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29811; Mature: 29811

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTTGLIGKNINYSESPEIHNNYYKKNNIPFFYKIFNLKQDQIDDFIKNLHKNNIKGFNV
CCCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEE
TIPYKETILQYLNDIVYPADKIEAVNTVAVQEDKLIGYNTDYIGFIKSLQYYNIQVKNFK
EECHHHHHHHHHHHHCCCCHHHHHEEEEEEECCCEEECCCHHHHHHHCEEEEEEEECCEE
CLIIGSGGSAKCIYYALKELNARDICIVSRNPEKARLKFEKKVKILNIKDENKLDRYDLI
EEEEECCCCCEEHEEEHHHCCCCEEEEEECCCCHHHEEEECCEEEEEECCCCCCCEEEEE
INCTPIGGPNFKEQKPIELKEIKKNCVVYDLNYTPKRSKLLKEAKENGAFIINGEKMLIF
EEEEECCCCCCCCCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCEEEEE
QAYSAIGLWCLNGIKGGR
EEHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYTTGLIGKNINYSESPEIHNNYYKKNNIPFFYKIFNLKQDQIDDFIKNLHKNNIKGFNV
CCCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEE
TIPYKETILQYLNDIVYPADKIEAVNTVAVQEDKLIGYNTDYIGFIKSLQYYNIQVKNFK
EECHHHHHHHHHHHHCCCCHHHHHEEEEEEECCCEEECCCHHHHHHHCEEEEEEEECCEE
CLIIGSGGSAKCIYYALKELNARDICIVSRNPEKARLKFEKKVKILNIKDENKLDRYDLI
EEEEECCCCCEEHEEEHHHCCCCEEEEEECCCCHHHEEEECCEEEEEECCCCCCCEEEEE
INCTPIGGPNFKEQKPIELKEIKKNCVVYDLNYTPKRSKLLKEAKENGAFIINGEKMLIF
EEEEECCCCCCCCCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCEEEEE
QAYSAIGLWCLNGIKGGR
EEHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA