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The map label for this gene is nsr [H]

Identifier: 170754587

GI number: 170754587

Start: 1136488

End: 1137177

Strand: Direct

Name: nsr [H]

Synonym: CLD_3541

Alternate gene names: 170754587

Gene position: 1136488-1137177 (Clockwise)

Preceding gene: 170756629

Following gene: 170757771

Centisome position: 28.71

GC content: 25.65

Gene sequence:

>690_bases
ATGAAAAAAATTTTGAATAAAGATCTTTTAAACCATTATATTGATAAGCATAATATAGAAAGCATATTTGACAAGGATAT
ATTAAAATATGCACAACTTCATTTTTATGAAAAAGAGGAATACATATTAAAAGCAGAGTCTAATCTTGAATACTATTATT
TGATTGTAGATGGGAAAATCAAAATTTCGTATCCCTTTGAAAACGGTAAACCAATGCTTTTAAAGTTTTACAAAGACTTT
AATACTATAGGAGATTTAGAGCTTTTGAAAAACATTCCAATACTCTGCGACGTTGATGCAGTAGGAGATGCTTATTTAAT
AGCAATACCTTCAGATATACTTAGAAAAAAGCATTTAGATAATGTAAAGTTTTTACACCATTTAATAGACTCTTTAAGTG
AAAAACTTTATGCAACAATTAATAATAGCTCATATAATTTTGTATATCCGCTCATAAATAGGTTATCTAGTTATCTAGTT
GAACATATAGAAGACAAAAACTACATAATTTTAAATCCATCATTCTTAGAAATTGCTCAATTCCTCGGAACAACCTATAG
GCATTTAAATAGAACCTTTAAAGAACTTGAATCAAAATCAATTATAAAATGTGAGAATAAAACAATATATATATTAGATG
AAAATAGACTTAGGGCCCTATCTAAAAACTTTTATATAAAATCCTTATAA

Upstream 100 bases:

>100_bases
TATATAAATTACTCCTAGGTTTTGGTTTACAATAGGTTATAAATAAATTACAATAATTATATAAATTTTAATATGACATA
TGTCATGTTATGGAGGACTT

Downstream 100 bases:

>100_bases
TATTAGAATATTGTAAGGAATATGAGTAAAGGTGATCAATAGAATATCAGATGATGCTATTAAAATATGGAATTATAATC
CAATAAAGAATTTCAATAAT

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKKILNKDLLNHYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKIKISYPFENGKPMLLKFYKDF
NTIGDLELLKNIPILCDVDAVGDAYLIAIPSDILRKKHLDNVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLV
EHIEDKNYIILNPSFLEIAQFLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL

Sequences:

>Translated_229_residues
MKKILNKDLLNHYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKIKISYPFENGKPMLLKFYKDF
NTIGDLELLKNIPILCDVDAVGDAYLIAIPSDILRKKHLDNVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLV
EHIEDKNYIILNPSFLEIAQFLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL
>Mature_229_residues
MKKILNKDLLNHYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKIKISYPFENGKPMLLKFYKDF
NTIGDLELLKNIPILCDVDAVGDAYLIAIPSDILRKKHLDNVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLV
EHIEDKNYIILNPSFLEIAQFLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=168, Percent_Identity=25.5952380952381, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 27118; Mature: 27118

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILNKDLLNHYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKI
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECEE
KISYPFENGKPMLLKFYKDFNTIGDLELLKNIPILCDVDAVGDAYLIAIPSDILRKKHLD
EEEECCCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEEECCCCCEEEEECCHHHHHHHCCC
NVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLVEHIEDKNYIILNPSFLEIAQ
HHHHHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHH
FLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECHHHHHHHHCEEEECC
>Mature Secondary Structure
MKKILNKDLLNHYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKI
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECEE
KISYPFENGKPMLLKFYKDFNTIGDLELLKNIPILCDVDAVGDAYLIAIPSDILRKKHLD
EEEECCCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEEECCCCCEEEEECCHHHHHHHCCC
NVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLVEHIEDKNYIILNPSFLEIAQ
HHHHHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHH
FLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]