Click here to switch to the map view.

The map label for this gene is galE [C]

Identifier: 170754466

GI number: 170754466

Start: 2231922

End: 2232845

Strand: Reverse

Name: galE [C]

Synonym: CLD_2540

Alternate gene names: 170754466

Gene position: 2232845-2231922 (Counterclockwise)

Preceding gene: 170756709

Following gene: 170755253

Centisome position: 56.41

GC content: 28.25

Gene sequence:

>924_bases
ATGAAGGTATTAGTTAGTGGTGGTGCAGGATTTATAGGATCTAATTTAGTAGATAAACTTATAAATCTAGGACACAATGT
ATGTATAATAGATAATTTATCTACTGGAAATATAAATAATGTAAATAAAAAAGCTCAATTATATATAAATGATATTTTGG
ATCCTAATGTATCAAAAATATTTGAAAAGGAAAAGTTTGATATAGTCTATCATCTAGCAGCGCAGATAGATGTGCAAAAA
TCTATAACGAATCCTATATTTGATTCTAATGTAAATGTATGTGGTACTATAAATATAATAAATAATTGTGTTAACTATAA
TGTTAAAAAAATAGTATATTCTTCTTCAGCAGCTGTCTATGGTCATCCCGGATACTTACCTATAGATGAAAAACATGGAA
TAATGCCTATATCTTATTACGGATTATCTAAATATACTGCTGAAGAATATATAAGATTATTTAGTAATTTAAATAATTTA
GATTTCACCATACTTAGATATGCAAATGTATACGGAATAAGGCAAGATCCAAAGGGGGAAGGTGGCGTAATATCCATATT
TATGAATAGTTTATTAAAAAAACAACCACTATATATATTTGGAGATGGTAGTGCCCTAAGAGATTACATCTTTGTAGAAG
ATATCGTTGACGCTAATATTGCAGCTCTCAGCAGTGGAGGCAAAGAGAGATTTAATATAGGCACTGGGGTTTATACTTCT
GTCGAGGAACTAGCTGAAAATATGATAGATATCGTTGGCCTAAAATGTAATATAGAGTATGCACCAGCTAGAAAAGGAGA
TATAGCAAATTCATATTTTAATATTAGTAAAGCTAAAAATAAACTTAACTGGATTCCAAAATTTAGTTTGAAAAATGGAC
TGAAGAAAACTATAGAATATTATAAAAATAATCTGGAAAATTAA

Upstream 100 bases:

>100_bases
TATTTTCACAATATGATACCTATCATAATATTATGAAAATATGGATTACTACATCCATTAGTTGGTTATTTTAATTTGCT
GTAAAAAAGGAGAGGGCTTT

Downstream 100 bases:

>100_bases
AAAGTAAAAAAGGAGAACGTAGCAAGTCTTAGTTGTTTGAGCAAATAGAGCCTGTAAAAAATTTTGTGTAAACCCCAATG
GAAGGATGATTTTGCTTATT

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKIFEKEKFDIVYHLAAQIDVQK
SITNPIFDSNVNVCGTINIINNCVNYNVKKIVYSSSAAVYGHPGYLPIDEKHGIMPISYYGLSKYTAEEYIRLFSNLNNL
DFTILRYANVYGIRQDPKGEGGVISIFMNSLLKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGGKERFNIGTGVYTS
VEELAENMIDIVGLKCNIEYAPARKGDIANSYFNISKAKNKLNWIPKFSLKNGLKKTIEYYKNNLEN

Sequences:

>Translated_307_residues
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKIFEKEKFDIVYHLAAQIDVQK
SITNPIFDSNVNVCGTINIINNCVNYNVKKIVYSSSAAVYGHPGYLPIDEKHGIMPISYYGLSKYTAEEYIRLFSNLNNL
DFTILRYANVYGIRQDPKGEGGVISIFMNSLLKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGGKERFNIGTGVYTS
VEELAENMIDIVGLKCNIEYAPARKGDIANSYFNISKAKNKLNWIPKFSLKNGLKKTIEYYKNNLEN
>Mature_307_residues
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKIFEKEKFDIVYHLAAQIDVQK
SITNPIFDSNVNVCGTINIINNCVNYNVKKIVYSSSAAVYGHPGYLPIDEKHGIMPISYYGLSKYTAEEYIRLFSNLNNL
DFTILRYANVYGIRQDPKGEGGVISIFMNSLLKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGGKERFNIGTGVYTS
VEELAENMIDIVGLKCNIEYAPARKGDIANSYFNISKAKNKLNWIPKFSLKNGLKKTIEYYKNNLEN

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=32.6409495548961, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=32.6409495548961, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=32.6409495548961, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=29.2063492063492, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI7657641, Length=323, Percent_Identity=33.7461300309598, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI193211614, Length=231, Percent_Identity=26.4069264069264, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI8393516, Length=231, Percent_Identity=26.4069264069264, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=30.0595238095238, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=28.8235294117647, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI48994969, Length=336, Percent_Identity=27.3809523809524, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790049, Length=270, Percent_Identity=30, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788365, Length=325, Percent_Identity=20, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788589, Length=339, Percent_Identity=22.1238938053097, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=330, Percent_Identity=34.2424242424242, Blast_Score=151, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71982038, Length=332, Percent_Identity=34.0361445783133, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17539532, Length=316, Percent_Identity=28.4810126582279, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17568069, Length=323, Percent_Identity=29.4117647058824, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI115532424, Length=321, Percent_Identity=26.791277258567, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319493, Length=338, Percent_Identity=31.0650887573964, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=30.5732484076433, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=31.9526627218935, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34184; Mature: 34184

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKI
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHH
FEKEKFDIVYHLAAQIDVQKSITNPIFDSNVNVCGTINIINNCVNYNVKKIVYSSSAAVY
HHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCEEEEEEECCCEEE
GHPGYLPIDEKHGIMPISYYGLSKYTAEEYIRLFSNLNNLDFTILRYANVYGIRQDPKGE
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHEEECCCCCCC
GGVISIFMNSLLKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGGKERFNIGTGVYTS
CCEEHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCHHHHCCCCCEEEEECCCHHHH
VEELAENMIDIVGLKCNIEYAPARKGDIANSYFNISKAKNKLNWIPKFSLKNGLKKTIEY
HHHHHHHHHHHEEEEEEEEECCCCCCCCCHHHEEHHHHHHHHCCCCCHHHHHHHHHHHHH
YKNNLEN
HHHCCCC
>Mature Secondary Structure
MKVLVSGGAGFIGSNLVDKLINLGHNVCIIDNLSTGNINNVNKKAQLYINDILDPNVSKI
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHH
FEKEKFDIVYHLAAQIDVQKSITNPIFDSNVNVCGTINIINNCVNYNVKKIVYSSSAAVY
HHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCEEEEEEECCCEEE
GHPGYLPIDEKHGIMPISYYGLSKYTAEEYIRLFSNLNNLDFTILRYANVYGIRQDPKGE
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHEEECCCCCCC
GGVISIFMNSLLKKQPLYIFGDGSALRDYIFVEDIVDANIAALSSGGKERFNIGTGVYTS
CCEEHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCHHHHCCCCCEEEEECCCHHHH
VEELAENMIDIVGLKCNIEYAPARKGDIANSYFNISKAKNKLNWIPKFSLKNGLKKTIEY
HHHHHHHHHHHEEEEEEEEECCCCCCCCCHHHEEHHHHHHHHCCCCCHHHHHHHHHHHHH
YKNNLEN
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]