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The map label for this gene is pdxK

Identifier: 170754448

GI number: 170754448

Start: 1552599

End: 1553435

Strand: Direct

Name: pdxK

Synonym: CLD_3149

Alternate gene names: 170754448

Gene position: 1552599-1553435 (Clockwise)

Preceding gene: 170754468

Following gene: 170757622

Centisome position: 39.22

GC content: 28.79

Gene sequence:

>837_bases
ATGAAAGTAGATACAAAAAAAGTAGCGGCTATACATGATATATCTGGTTATGGGAGAGCATCCTTGACTACAGTAATACC
TATAATATCTCTTATGGGTACGCAGGTATGTCCAATTCCCACAGCGGTTTTGTCTACTCATACAGGGGGATTTGGTAGTC
CTGAAATAATAGATTTAACAGATAATTTACAGGCTTATATAAATCATTGGAAAAGCTTAAATTTAGATTTTAATTGCATA
TATAGTGGATATTTAGGATCAGTGCATCAAATAAATATAATATCAAGTTTTATAAAGTATTTTAAGAAGAAAGATACATT
GGTAGTTATAGATCCAGTAATGGGAGATGATTGTGAGCTTTATTCTGCTATAGATTATGAAATGGTACATAAAATGAGAG
AATTCATAAAATTAGCCCATGTTATAACGCCAAATTACACTGAAGCTTGTTATCTTTTAAATAAGGATTGTTCTAAATGC
AAAATTTCCGAAAAAGAAGTTAAAAAAATGCTTATAAGCTTAAGTGATATAGGACCAGAAAATGTTATAATAACCAGTGT
TCCCTTATATGATAATATAATAGCTACAGTTTCATACAATAAAGCAAATGAAGAATTTTATATAGCAAAAACGGAGAAAT
TAAATGTAAATTATCCTGGTACAGGAGATGCTTTTACTAGTGTAATTGTAGGAAGCTTATTAAAAGGAGAAGACATAAAA
ACTGCCGTAGATAAGGCTGTTGATTTTATAAAGTATGGTATAGAAATAAGTTTGAAATATGATTATAATCAAAGAGATGG
TATTTTATTAGAAAAAGCTTTAAAAAAGTTAATATAG

Upstream 100 bases:

>100_bases
ATCCAGGGACGTAACCGCTCTTTACTCCCACTTTAAAGAAGATGGGAGTATTAGAGCGGGTAGTCATCGGATAAATTGAA
ATTGTTTAGGAGATGGACAT

Downstream 100 bases:

>100_bases
AATAGAATCAGGTATTTCAGTCTTAGATAGATCTGTCTTATAAGGAGACATTTTTGTGTGAATCTTAAAAAACTATCTAG
GAAGATGCTTAGCATTATGG

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PN/PL/PM kinase; Pyridoxal kinase; Pyridoxamine kinase; Vitamin B6 kinase [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGTQVCPIPTAVLSTHTGGFGSPEIIDLTDNLQAYINHWKSLNLDFNCI
YSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCELYSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCSKC
KISEKEVKKMLISLSDIGPENVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGEDIK
TAVDKAVDFIKYGIEISLKYDYNQRDGILLEKALKKLI

Sequences:

>Translated_278_residues
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGTQVCPIPTAVLSTHTGGFGSPEIIDLTDNLQAYINHWKSLNLDFNCI
YSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCELYSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCSKC
KISEKEVKKMLISLSDIGPENVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGEDIK
TAVDKAVDFIKYGIEISLKYDYNQRDGILLEKALKKLI
>Mature_278_residues
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGTQVCPIPTAVLSTHTGGFGSPEIIDLTDNLQAYINHWKSLNLDFNCI
YSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCELYSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCSKC
KISEKEVKKMLISLSDIGPENVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGEDIK
TAVDKAVDFIKYGIEISLKYDYNQRDGILLEKALKKLI

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788758, Length=256, Percent_Identity=25.390625, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31001; Mature: 31001

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGTQVCPIPTAVLSTHTGGFGSPEIIDLT
CCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCEEEECH
DNLQAYINHWKSLNLDFNCIYSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCEL
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHH
YSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCSKCKISEKEVKKMLISLSDIGPE
HHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCC
NVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGEDIK
CEEEEECCCCCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCHH
TAVDKAVDFIKYGIEISLKYDYNQRDGILLEKALKKLI
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MKVDTKKVAAIHDISGYGRASLTTVIPIISLMGTQVCPIPTAVLSTHTGGFGSPEIIDLT
CCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCEEEECH
DNLQAYINHWKSLNLDFNCIYSGYLGSVHQINIISSFIKYFKKKDTLVVIDPVMGDDCEL
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHH
YSAIDYEMVHKMREFIKLAHVITPNYTEACYLLNKDCSKCKISEKEVKKMLISLSDIGPE
HHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCC
NVIITSVPLYDNIIATVSYNKANEEFYIAKTEKLNVNYPGTGDAFTSVIVGSLLKGEDIK
CEEEEECCCCCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCHH
TAVDKAVDFIKYGIEISLKYDYNQRDGILLEKALKKLI
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA