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The map label for this gene is gpsA

Identifier: 170754351

GI number: 170754351

Start: 2644633

End: 2645631

Strand: Reverse

Name: gpsA

Synonym: CLD_2117

Alternate gene names: 170754351

Gene position: 2645631-2644633 (Counterclockwise)

Preceding gene: 170757031

Following gene: 170755939

Centisome position: 66.84

GC content: 32.23

Gene sequence:

>999_bases
ATGGATTCAACAGTTTGTTTTTTAGGAGCAGGTAGTTTTGGAACAGCTTTAGCTGTAATGCTAGGAAAAAAAGGATTGAA
AGTTAACATATGGCATAGAAATAATAACATAGTAGAGGATATAAATATCAAAAAAGAAAATATAAAATATTTACCTAAAG
TAGTAATACCTGCAGGGATAAAAGCTTATAATGAAATAGAAAAAAGTATAGAGCAATGTGAATTTATAGTATTAGCAGTA
CCTTCTCATGTGGTAAGACAGGTATGCAAAAAAATACAACCTTTTATAAAAGAAAATCAAATAATAGTAAGTATAGCTAA
AGGTATAGAAGAGGGTACAGGGAAAAGGTTATCAGAGGTTATAAAAGAAGAACTGCCTAATAATCCTATAGTAATATTGT
CAGGCCCTAGTCATGCAGAGGAAGTAGCTCAAGATATACCTACCACAGTAGTTGTGTCTTCAGAACATATGGATATAGCT
GAAAAAGTTCAGGATCTTTTTATGACTAATAAATTTAGAGTGTATACTAATGATGATTTAATAGGAGTAGAAATAGGAGG
CGCTGTTAAAAATATTATAGCTTTAGCTGCAGGGGTATCTGATGGTATAGGTTACGGAGATAACACAAAGGCAGCTTTAA
TGACAAGAGGTATGAGTGAGATAATAAGAATAGGTACAAAGCTTGGAGGAAAACAGGAAACCTTTTCAGGTCTTACAGGC
ATGGGAGATTTAATAGTTACTTGCACAAGTATGCATAGTAGAAATAGAAGGGCGGGTATATTAATTGGTAAAGGTTATAG
CACGGAAGAAGCAATAGAAGAGGTAGGTATGGTAGTAGAAGGGATAAAAGCTTGTAGAGCCTTTTATACATTAAAAGAAA
AGCTAGATGTAGAAATGCCTATAACAGATACATTATATAAAGTTTTATTTGAAAATAAAGAGCCTAATTATGGGGTCTAT
GAACTTATGACTAGGGATAAAAAAATGGAAATAATTTAA

Upstream 100 bases:

>100_bases
ATAGGAATTTTTAATATAAACTTATTTCTTAAATTAATTTTAAAGATCAATTGAAAATTTTAATTAGGTTAATAATTAAT
TGGGGAAAGGAAGGAATAAA

Downstream 100 bases:

>100_bases
GATATTAATTATATATAAAGTGCTAATCTAAAGGTAGAAGATGTCTTCTACCTTTTAGATTAGTGCTTTTTACATTATCT
TAAGAATAGCAACTGACGCT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MDSTVCFLGAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGIKAYNEIEKSIEQCEFIVLAV
PSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEVIKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIA
EKVQDLFMTNKFRVYTNDDLIGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMPITDTLYKVLFENKEPNYGVY
ELMTRDKKMEII

Sequences:

>Translated_332_residues
MDSTVCFLGAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGIKAYNEIEKSIEQCEFIVLAV
PSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEVIKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIA
EKVQDLFMTNKFRVYTNDDLIGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMPITDTLYKVLFENKEPNYGVY
ELMTRDKKMEII
>Mature_332_residues
MDSTVCFLGAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGIKAYNEIEKSIEQCEFIVLAV
PSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEVIKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIA
EKVQDLFMTNKFRVYTNDDLIGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMPITDTLYKVLFENKEPNYGVY
ELMTRDKKMEII

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=347, Percent_Identity=29.1066282420749, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI24307999, Length=332, Percent_Identity=30.421686746988, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=38.368580060423, Blast_Score=266, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI32564399, Length=335, Percent_Identity=30.7462686567164, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI193210136, Length=344, Percent_Identity=30.2325581395349, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI32564403, Length=344, Percent_Identity=30.2325581395349, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17507425, Length=333, Percent_Identity=26.4264264264264, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI193210134, Length=332, Percent_Identity=28.3132530120482, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324513, Length=340, Percent_Identity=28.5294117647059, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320181, Length=340, Percent_Identity=28.5294117647059, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136204, Length=335, Percent_Identity=30.1492537313433, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI17136200, Length=335, Percent_Identity=30.1492537313433, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI17136202, Length=335, Percent_Identity=30.1492537313433, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI22026922, Length=326, Percent_Identity=29.1411042944785, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI45551945, Length=294, Percent_Identity=26.530612244898, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281362270, Length=294, Percent_Identity=26.530612244898, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24648969, Length=255, Percent_Identity=27.4509803921569, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36484; Mature: 36484

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTVCFLGAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGI
CCCCEEEEECCCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCHHHHHHCCHHHCCCCH
KAYNEIEKSIEQCEFIVLAVPSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEV
HHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCHHHHHH
IKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIAEKVQDLFMTNKFRVYTNDDL
HHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCE
IGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
EEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMP
CCHHHHEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ITDTLYKVLFENKEPNYGVYELMTRDKKMEII
HHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MDSTVCFLGAGSFGTALAVMLGKKGLKVNIWHRNNNIVEDINIKKENIKYLPKVVIPAGI
CCCCEEEEECCCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCHHHHHHCCHHHCCCCH
KAYNEIEKSIEQCEFIVLAVPSHVVRQVCKKIQPFIKENQIIVSIAKGIEEGTGKRLSEV
HHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCHHHHHH
IKEELPNNPIVILSGPSHAEEVAQDIPTTVVVSSEHMDIAEKVQDLFMTNKFRVYTNDDL
HHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCE
IGVEIGGAVKNIIALAAGVSDGIGYGDNTKAALMTRGMSEIIRIGTKLGGKQETFSGLTG
EEEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
MGDLIVTCTSMHSRNRRAGILIGKGYSTEEAIEEVGMVVEGIKACRAFYTLKEKLDVEMP
CCHHHHEEHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ITDTLYKVLFENKEPNYGVYELMTRDKKMEII
HHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]