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The map label for this gene is tlpB [H]

Identifier: 170754326

GI number: 170754326

Start: 2994306

End: 2996366

Strand: Reverse

Name: tlpB [H]

Synonym: CLD_1763

Alternate gene names: 170754326

Gene position: 2996366-2994306 (Counterclockwise)

Preceding gene: 170757361

Following gene: 170755249

Centisome position: 75.7

GC content: 33.33

Gene sequence:

>2061_bases
ATGAAAGTTAAAAGCATTGTCCAAAAGAGTATCTTTGCCAAAATGATGTTGTATATTCTCACAGCAGTATTTGTTGTATT
TTTAGCATCTGGTATTTTTTTAGAGCTAAAGATCAAAGATATTGTGACTAAAATGAATTATGAGCATCTTTTGACGGAAG
CAAAGGCAGCTTCTAATCAAAACAATGAATTTTTTAAAAAGAATGAAGTATTAGTAAGACAGATGGCAACTAACCAAGAT
ATTATAAAATTAATGAAAGGTGTAAGAACTAGGGATAAAGTTCGAAGTCATCCAGATTATAAAGATGTAATAAACTCTTT
ACAACAAATAAAAAAGATAGATAAAAATCTTGCTATGGTATGGATTGGTCTACAGGATGCTAGTTATTTAGTTACTCAAG
ATCAATGGGACTCTCCAACAGATTGGATTATTAAGGAAAAGCCTTGGTATAAAGAAGCTTTAAAATTAAAACCTGGGGAA
GTGCTTTACACAGAACCTTATGTAGATTCTGTAACAGGAAAGATGGTAATTAGTGTTATACAGGTAGTATATGATGAGAA
AGGAACTAGTTTAGGCGTAGTGGCTATAGATGTACTACTTGATGAATTACCTAGTATTATGCAGAAATATAAGATTGGTG
AAAGTGGTTTTGTATTCCTAATAAGTAAAAAAGGTGAACTAGCTTATCACCCTGTAAAAGAAATGGTTTTAAAAAATAAT
ATGACAAAAGAAAAAGGTGAAATGGGAGACATAGGAAGAAATATGGTTGCACAAAAGCAGGGCACAGGAATGTATTCTTA
TAAAGATCAGCATAAATATGTAGGGTATTATCCTATATCCGCTAATGGATGGTCTGTTGCAGCCGTAATAGACCAAAGTG
AATTTAATGAAAAAGTTTCTATGGTAAGAAACCTACTTATTATCTCCTATGCATTAGGAGCAATTATTATTGCAGCGCTA
ATTTATCTAGTAGGGAAAGCTATAGTAAAACCTATTAAAAGTCTTGAAGGATATGGACATAAAATGGCAGACCTAGATTT
TACAGAAGATATATCAAGGGAGCTAGTGGAAAAGGAAGATGAAATAGGATTATTAGCAAAGGCTTTTGAAAATGTTTCTG
TAAATCTAAGAGATTTTGCTAGAAAAACTTTAGAAAGTGCAGAGCAGGTAGCAGCCTCATCAGAGGAGCTTACCTCTACT
AGTCAACAAACTGCAGAAGCAGCAAATGAAATTACTAAAACTATAGAGGAAATGGCTGATTCTGCAGAAGATCAAGCAAG
GCAAACAGAAAATGGTGCTATAAATGTAAATGTCCTTGGAGAGACAATTTCAAAAAATCAACAGATGATGGATAGTTTAA
ATAAGGCTATAGAAAAAGTAGATATTTTAAAAAATGAAGGGGTAACTACTTTAAAAGAACTAGTAGAAAAAACTATGGAC
AGTGAAAAGATATCAAAGGAAGTATATAAGGTAATTATTGATAGCAATAAGAGTGCAGAAAAAATTGAAAATGCTAGCGA
GATGATAAAGAGTATAGCATCTCAGACTAATCTTTTAGCTTTAAATGCAGCTATTGAGGCAGCAAGGGCAGGAGAATCAG
GTAAAGGTTTTGCTGTGGTAGCAGACGAAATAAGAAAGTTAGCAGAGCAATCTAATGCTTTTACCGATGAAATTGCTTTG
GTAATTAATGAATTAGCAGTTCAGACAGAGAAAGCAGTTGGGAGTATGGAAATAGTCAGTGATAATACGAAAAAGCAAAC
TAAGAGCGTAGAAAACACAAATAAAAAATTTGAAGGTATTTCTATAGCTATTGATGAAATGCAGGAAGTAGTACAAACAT
TAAATGAATCAGGAAAGGATATGGAAAGCAAGAAGAATGAAATCATTACAGTAATTGATAATTTATCTGCTATTTCCCAG
GAAAATGCTGCGGGGACAGAAGAGACAGTGGCTGCAGTAGAAGAACAAACCGCTTCTATCTCGGAGTTAGCTAATGCCAG
TGAGTCTTTAGCTAGGCTAGCAGAGGACATGCAGGTTAATATTTCTAGGTTTAAATATTAA

Upstream 100 bases:

>100_bases
TATTTTCTGATATATAATGAAAATAGTAAAAGATAATGGTATAAAATCTAGTAAAAAAGGGGAGGAAACAGGATTTTACC
AATATAGAGGGGGAGAATAA

Downstream 100 bases:

>100_bases
ATATTTTTAAATTGAGCATTACATGGGCTGAATAGTATTTTAAACAAATATTATTCAGCTTATTTTCATCTAATGGATGG
GATTGAAAAATCAATAAAAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELKIKDIVTKMNYEHLLTEAKAASNQNNEFFKKNEVLVRQMATNQD
IIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMVWIGLQDASYLVTQDQWDSPTDWIIKEKPWYKEALKLKPGE
VLYTEPYVDSVTGKMVISVIQVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQHKYVGYYPISANGWSVAAVIDQSEFNEKVSMVRNLLIISYALGAIIIAAL
IYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKEDEIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTST
SQQTAEAANEITKTIEEMADSAEDQARQTENGAINVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVVADEIRKLAEQSNAFTDEIAL
VINELAVQTEKAVGSMEIVSDNTKKQTKSVENTNKKFEGISIAIDEMQEVVQTLNESGKDMESKKNEIITVIDNLSAISQ
ENAAGTEETVAAVEEQTASISELANASESLARLAEDMQVNISRFKY

Sequences:

>Translated_686_residues
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELKIKDIVTKMNYEHLLTEAKAASNQNNEFFKKNEVLVRQMATNQD
IIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMVWIGLQDASYLVTQDQWDSPTDWIIKEKPWYKEALKLKPGE
VLYTEPYVDSVTGKMVISVIQVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQHKYVGYYPISANGWSVAAVIDQSEFNEKVSMVRNLLIISYALGAIIIAAL
IYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKEDEIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTST
SQQTAEAANEITKTIEEMADSAEDQARQTENGAINVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVVADEIRKLAEQSNAFTDEIAL
VINELAVQTEKAVGSMEIVSDNTKKQTKSVENTNKKFEGISIAIDEMQEVVQTLNESGKDMESKKNEIITVIDNLSAISQ
ENAAGTEETVAAVEEQTASISELANASESLARLAEDMQVNISRFKY
>Mature_686_residues
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELKIKDIVTKMNYEHLLTEAKAASNQNNEFFKKNEVLVRQMATNQD
IIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMVWIGLQDASYLVTQDQWDSPTDWIIKEKPWYKEALKLKPGE
VLYTEPYVDSVTGKMVISVIQVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQHKYVGYYPISANGWSVAAVIDQSEFNEKVSMVRNLLIISYALGAIIIAAL
IYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKEDEIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTST
SQQTAEAANEITKTIEEMADSAEDQARQTENGAINVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVVADEIRKLAEQSNAFTDEIAL
VINELAVQTEKAVGSMEIVSDNTKKQTKSVENTNKKFEGISIAIDEMQEVVQTLNESGKDMESKKNEIITVIDNLSAISQ
ENAAGTEETVAAVEEQTASISELANASESLARLAEDMQVNISRFKY

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=369, Percent_Identity=27.3712737127371, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787690, Length=364, Percent_Identity=27.1978021978022, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=25.4601226993865, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788195, Length=333, Percent_Identity=25.5255255255255, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788194, Length=395, Percent_Identity=24.3037974683544, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 76194; Mature: 76194

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELKIKDIVTKMNYEHLLTEAKAASNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
NNEFFKKNEVLVRQMATNQDIIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMV
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEE
WIGLQDASYLVTQDQWDSPTDWIIKEKPWYKEALKLKPGEVLYTEPYVDSVTGKMVISVI
EEEECCCCEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
QVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
HHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCC
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQHKYVGYYPISANGWSVAAVIDQSEFNEKVS
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECHHHHHHHHH
MVRNLLIISYALGAIIIAALIYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCH
EIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTSTSQQTAEAANEITKTIEEMAD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAEDQARQTENGAINVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
HHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCHHHH
ADEIRKLAEQSNAFTDEIALVINELAVQTEKAVGSMEIVSDNTKKQTKSVENTNKKFEGI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCHHCCH
SIAIDEMQEVVQTLNESGKDMESKKNEIITVIDNLSAISQENAAGTEETVAAVEEQTASI
HHHHHHHHHHHHHHCCCCCCHHHHCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
SELANASESLARLAEDMQVNISRFKY
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVKSIVQKSIFAKMMLYILTAVFVVFLASGIFLELKIKDIVTKMNYEHLLTEAKAASNQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
NNEFFKKNEVLVRQMATNQDIIKLMKGVRTRDKVRSHPDYKDVINSLQQIKKIDKNLAMV
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEE
WIGLQDASYLVTQDQWDSPTDWIIKEKPWYKEALKLKPGEVLYTEPYVDSVTGKMVISVI
EEEECCCCEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
QVVYDEKGTSLGVVAIDVLLDELPSIMQKYKIGESGFVFLISKKGELAYHPVKEMVLKNN
HHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCC
MTKEKGEMGDIGRNMVAQKQGTGMYSYKDQHKYVGYYPISANGWSVAAVIDQSEFNEKVS
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECHHHHHHHHH
MVRNLLIISYALGAIIIAALIYLVGKAIVKPIKSLEGYGHKMADLDFTEDISRELVEKED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCH
EIGLLAKAFENVSVNLRDFARKTLESAEQVAASSEELTSTSQQTAEAANEITKTIEEMAD
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAEDQARQTENGAINVNVLGETISKNQQMMDSLNKAIEKVDILKNEGVTTLKELVEKTMD
HHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
SEKISKEVYKVIIDSNKSAEKIENASEMIKSIASQTNLLALNAAIEAARAGESGKGFAVV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCHHHH
ADEIRKLAEQSNAFTDEIALVINELAVQTEKAVGSMEIVSDNTKKQTKSVENTNKKFEGI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCHHCCH
SIAIDEMQEVVQTLNESGKDMESKKNEIITVIDNLSAISQENAAGTEETVAAVEEQTASI
HHHHHHHHHHHHHHCCCCCCHHHHCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
SELANASESLARLAEDMQVNISRFKY
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]