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The map label for this gene is intA [H]

Identifier: 170752117

GI number: 170752117

Start: 6055547

End: 6056770

Strand: Reverse

Name: intA [H]

Synonym: Mrad2831_5749

Alternate gene names: 170752117

Gene position: 6056770-6055547 (Counterclockwise)

Preceding gene: 170752119

Following gene: 170752099

Centisome position: 99.65

GC content: 71.16

Gene sequence:

>1224_bases
ATGGCGCGCGAGATCAACCGTCTCTCGGCGCGCAAGGTGCAGACGATGAACGAGCCGGGCCGGCACGCCGACGGCGGCGG
CCTGTACCTCGTGGTCGAGGCTAGCGGATCGAAGCGCTGGGTCATGTTGTACCGCATGCCCGGGCGCCGGCGCGAGATGG
GGCTCGGCTCGGTCGGATCGGTTTCGCTGGCCCGAGCGCGTGAATTGGCCGCGGCCGCCCGCGCGCAGATCGCCGATGGT
ATCGACCCGATCGAAGCGAAAGCGGCCGCCGCTGAGCCCCGTGCCCCAGCCGCCCCGGTCGCCTTCTCCGACGTCGCCCT
GACCTACATGGCAGACCGGGAGAGCACTTGGAGAAACGCGTCGCACCGGGCGCAATGGCGGCAGACGCTGGAGGTCCAGG
CCGCGAGCCTCTGGAGCATGCCGGTGGCCGATATCGGCACCGACGACGTCCTCGCCGTGCTCCGGCCCATGTGGCACGAG
AAGGCCGAAACGGCGCGCCGGATCCGCGGGCGCATCGAGCGCGTGCTGGATGCCGCGCGAGTCGGCGGCCATCGGTCCGG
AGAGAACCCGGCGCGCTGGCGCGGCCATCTCGATGTGCTGCTGCCGCAATCCCGCAAGCTCACGCGCGGCCACCACAAGG
CGATGCCCTACGCGGAGGTGCCGGCCTTCTACGCGGCGATCGCGGCCGGGCGCACGAGCTTCTCCTCGCTCGCGCTGCGC
TTCACGATCCTGACAGCCGCCCGGTCGGGTGAGACCCGGGGGCTGACCTGGGGTGAGGTCGACATGGGCGCCGCGCTCTG
GACGGTACCGGCGCCGCGCATGAAGGCGGGGCGACAGCATCGCGTGCCCCTCTCTTCGGCAGCTATCGCCATCCTGGCAT
CAGTTCGGCCGGGCGGCGCGAGAGCGGAGGATCTCGTCTTCCCGTCCCGGGCCGGATCCAGATTGTCGGACATGGCCCTG
GCGATGTTCCTGCGCGGCGCCAATCCGAGCGGCTTCACCGTGCATGGGTTCCGGTCATCCTTCCGGGACTGGGTGACCGA
GGAGACCGACTTCCCGGGCGAGCTGGCGGAGGCCGCGCTCGCGCATCTCGTCGGCGATGAGACGGAACGCGCCTATCGCC
GCGGCGACGCCCTGGAGAAGCGTCGTCACTTGATGGACGCCTGGGCCGCCTTCGTAGCGGCCGACAAGGCGGCGCCGTCG
AGCACGCGCGCCAGCTCGGAGTGA

Upstream 100 bases:

>100_bases
TCCCTTGCGATCATAGGCCGTTGCCCGCCAGAAATTCCACGGGTGTTCGCCCCTGTCCGCCACAATCGGCGGCAAATGGT
GGGGTGACTGGTGGGGTCGG

Downstream 100 bases:

>100_bases
GGAATCACCGTCGCTGATCCGAGCTTGCGCGCCGAGAGCTGCCCGTCGGCGATCATCTGGTAGATCGTCGAGCGGCTGAC
ACCGAGCACAGCCGCAGCAT

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MAREINRLSARKVQTMNEPGRHADGGGLYLVVEASGSKRWVMLYRMPGRRREMGLGSVGSVSLARARELAAAARAQIADG
IDPIEAKAAAAEPRAPAAPVAFSDVALTYMADRESTWRNASHRAQWRQTLEVQAASLWSMPVADIGTDDVLAVLRPMWHE
KAETARRIRGRIERVLDAARVGGHRSGENPARWRGHLDVLLPQSRKLTRGHHKAMPYAEVPAFYAAIAAGRTSFSSLALR
FTILTAARSGETRGLTWGEVDMGAALWTVPAPRMKAGRQHRVPLSSAAIAILASVRPGGARAEDLVFPSRAGSRLSDMAL
AMFLRGANPSGFTVHGFRSSFRDWVTEETDFPGELAEAALAHLVGDETERAYRRGDALEKRRHLMDAWAAFVAADKAAPS
STRASSE

Sequences:

>Translated_407_residues
MAREINRLSARKVQTMNEPGRHADGGGLYLVVEASGSKRWVMLYRMPGRRREMGLGSVGSVSLARARELAAAARAQIADG
IDPIEAKAAAAEPRAPAAPVAFSDVALTYMADRESTWRNASHRAQWRQTLEVQAASLWSMPVADIGTDDVLAVLRPMWHE
KAETARRIRGRIERVLDAARVGGHRSGENPARWRGHLDVLLPQSRKLTRGHHKAMPYAEVPAFYAAIAAGRTSFSSLALR
FTILTAARSGETRGLTWGEVDMGAALWTVPAPRMKAGRQHRVPLSSAAIAILASVRPGGARAEDLVFPSRAGSRLSDMAL
AMFLRGANPSGFTVHGFRSSFRDWVTEETDFPGELAEAALAHLVGDETERAYRRGDALEKRRHLMDAWAAFVAADKAAPS
STRASSE
>Mature_406_residues
AREINRLSARKVQTMNEPGRHADGGGLYLVVEASGSKRWVMLYRMPGRRREMGLGSVGSVSLARARELAAAARAQIADGI
DPIEAKAAAAEPRAPAAPVAFSDVALTYMADRESTWRNASHRAQWRQTLEVQAASLWSMPVADIGTDDVLAVLRPMWHEK
AETARRIRGRIERVLDAARVGGHRSGENPARWRGHLDVLLPQSRKLTRGHHKAMPYAEVPAFYAAIAAGRTSFSSLALRF
TILTAARSGETRGLTWGEVDMGAALWTVPAPRMKAGRQHRVPLSSAAIAILASVRPGGARAEDLVFPSRAGSRLSDMALA
MFLRGANPSGFTVHGFRSSFRDWVTEETDFPGELAEAALAHLVGDETERAYRRGDALEKRRHLMDAWAAFVAADKAAPSS
TRASSE

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=384, Percent_Identity=30.2083333333333, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1788690, Length=381, Percent_Identity=27.8215223097113, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI145693166, Length=383, Percent_Identity=31.8537859007833, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44288; Mature: 44157

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAREINRLSARKVQTMNEPGRHADGGGLYLVVEASGSKRWVMLYRMPGRRREMGLGSVGS
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCHHHCCCCCCCC
VSLARARELAAAARAQIADGIDPIEAKAAAAEPRAPAAPVAFSDVALTYMADRESTWRNA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHHHEEEECCCCHHHCCH
SHRAQWRQTLEVQAASLWSMPVADIGTDDVLAVLRPMWHEKAETARRIRGRIERVLDAAR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGHRSGENPARWRGHLDVLLPQSRKLTRGHHKAMPYAEVPAFYAAIAAGRTSFSSLALR
HCCCCCCCCCHHHCCCEEEECCCCCCHHCCHHHCCCHHHHHHHHHHHHHCCCHHHHHHHH
FTILTAARSGETRGLTWGEVDMGAALWTVPAPRMKAGRQHRVPLSSAAIAILASVRPGGA
HHEEEHHCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
RAEDLVFPSRAGSRLSDMALAMFLRGANPSGFTVHGFRSSFRDWVTEETDFPGELAEAAL
CHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHH
AHLVGDETERAYRRGDALEKRRHLMDAWAAFVAADKAAPSSTRASSE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AREINRLSARKVQTMNEPGRHADGGGLYLVVEASGSKRWVMLYRMPGRRREMGLGSVGS
CCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCHHHCCCCCCCC
VSLARARELAAAARAQIADGIDPIEAKAAAAEPRAPAAPVAFSDVALTYMADRESTWRNA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHHHEEEECCCCHHHCCH
SHRAQWRQTLEVQAASLWSMPVADIGTDDVLAVLRPMWHEKAETARRIRGRIERVLDAAR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGHRSGENPARWRGHLDVLLPQSRKLTRGHHKAMPYAEVPAFYAAIAAGRTSFSSLALR
HCCCCCCCCCHHHCCCEEEECCCCCCHHCCHHHCCCHHHHHHHHHHHHHCCCHHHHHHHH
FTILTAARSGETRGLTWGEVDMGAALWTVPAPRMKAGRQHRVPLSSAAIAILASVRPGGA
HHEEEHHCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
RAEDLVFPSRAGSRLSDMALAMFLRGANPSGFTVHGFRSSFRDWVTEETDFPGELAEAAL
CHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHH
AHLVGDETERAYRRGDALEKRRHLMDAWAAFVAADKAAPSSTRASSE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]