Click here to switch to the map view.

The map label for this gene is livM [C]

Identifier: 170751878

GI number: 170751878

Start: 5823359

End: 5824531

Strand: Reverse

Name: livM [C]

Synonym: Mrad2831_5510

Alternate gene names: 170751878

Gene position: 5824531-5823359 (Counterclockwise)

Preceding gene: 170751879

Following gene: 170751877

Centisome position: 95.83

GC content: 66.16

Gene sequence:

>1173_bases
ATGACGAATCCGGTCCAGACCCTCACCAAATCCGTCACCGTCAACGACAACCCGTTCATGAAGCCGGTGGAGTGGCTCAG
CCTGCTCCTGCTCGCCGGGGTGATCCTGGTCGTCCTGCCGCTGGTGCTCGACGGCTTCCGCCTCAACCTCGTCGGCAAGT
ACCTGACCTACGCGTTCGTCGCCCTCGGGCTGGTGATCTGCTGGGGCTACGCGGGGATCCTGTCGCTCGGTCAGGGCGTG
TTCTTCGGCCTCGGCGGCTACTGCATGGCGATGTACTTGAAGCTCGAAGCGTCGAGCATCGAGAACACGAAGATCCAGTC
CACGCCCGGCATCCCGGACTTCATGGACTGGAACCAGATCACGGCCCTCCCCTGGTTCTGGCAGCCGTTCAAGAGCCTGC
CGCTGACGCTGATCCTGGCGGTCGCCGTCCCGGTCCTGTTCGCGATGCTGATCTCCTTCGCGATGTTCAAGCGCCGGGTC
GGCGGCACCTACTTCGCGATCATCACCCAGGCGATCGCCGCGATCCTGACCATCCTGATCGTCGGCCAGCAGGGCTATAC
CGGCGGCATCAACGGCATCACCGACCTGCGCACCCTCCACGGCTGGGACATCCGCACCGACCACGCGAAGGTCATCCTGT
ACTTCGTCAATGGCGGCCTGCTGATCGCCTGCATCCTGGCGGCGCAGTACGTGAAGAAGTCGAAGCTCGGCCGCATCCTC
GTCGCCATGCGCGATAAGGAGGACCGGGTCCGCTTCTCGGGTTACTCGGTCGCTGGATTCAAGGTCTTCGCCTTCTGCTT
CGCCGCCGGACTGGCGGCCATCGGCGGCGCGATGTTCACCCTCCAGGTCGGGTTCATGTCGCCCTCCTTCGTGGGCATCG
TCCCCTCGATCGAGATGGTGATCTACGCCGCGGTCGGCGGGCGCCTGTCGCTGTTCGGCGCGGTCTGGGGCACGCTGCTC
GTCAACTGGGCCAAGACCAGCTTCTCCGAGAGTTTTCCGGATCTCTGGCTGTTCGGCCTCGGCGCCCTGTTCATCGCGGT
GGTGCTGGCCTTCCCGAACGGCCTCGCCGGGATCTGGCGCGAGCATATCGAGCCGCGCCTCACCCGCCGGGTGAAGGGCC
TGCGCGCCCCGCCGCCCGCCATCGTCCCGCCCCACGGCGCCCCGGCCGAGTGA

Upstream 100 bases:

>100_bases
ATGGCCAAGGTGATCACCCTGCTCGCGGTGGTCGGCATCCTGATGCTGAGGCCCCAGGGCCTCTTCACCCTCAAGGTCCG
GCGCTGAGGATTTTTCGACC

Downstream 100 bases:

>100_bases
GTCTCCGATGAACGCCGCGATCCTCTCCTCCCCCGTGGTCGGCGCCGAGGCGGCCCCGCCCGACTACCTCCTCGCCGTCG
AGGCGCTCACGGTCTCGTTC

Product: urea ABC transporter permease UrtC

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: Inner-Membrane Translocator; Branched-Chain Amino Acid ABC Transporter Permease Protein; ABC Transporter Permease Protein; Urea ABC Transporter Permease UrtC; ABC Transporter ; Amino Acid Or Sugar ABC Transport System Permease Protein; Branched Chain Amino Acid ABC Transporter Permease; Branched-Chain Amino Acid Transport System Permease Protein; Branched-Chain Amino Acid ABC Transporter Permease; ABC Transporter Permease; ABC Transporter; Urea ABC Transporter Permease; Permease Of ABC Transporter; ABC Transporter Membrane Spanning Protein; Urea Or Short-Chain Amide ABC Transporter; Urea Or Short-Chain Amide ABC Transporter Permease Protein; Amide-Urea Transport System Permease Protein; Branched-Chain Amino Acid Inner-Membrane Translocator; Branched Chain Amino Acid ABC Transporter Permease Protein; Amide-Urea Transporter Permease Protein; Transmembrane Component Of ABC Transporter; High-Affinity Branched-Chain Amino Acid Transport System; Urea/Short Chain-Amide ABC Transporter Permease Protein; Urea ABC Transporter Permease Protein; ABC Transporter Related Protein; ABC Transporter Membrane Protein; Branched-Chain Amino Acid Transporter; ABC-Type Urea Transport System Permease Protein II; Urea Transport System Permease Protein; ABC Transporter Inner-Membrane Translocator; ABC-Type Transport System Permease Protein; ABC Transporter-Like Protein; Integral Membrane Protein; Urea ABC Transporter Inner-Membrane Subunit UrtC; ABC Branched Amino Acid Transporter Permease Component; Branched-Chain Amino Acid Transport System Permease; Permease Protein Of ABC Transporter; Urea Transport System Permease Component Protein; Permease Component Of ABC Transporter; Urea/Short Chain-Amides ABC Transporter Permease; Permease Transporter Transmembrane Protein; Urea ABC Transport Permease Component UrtC

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MTNPVQTLTKSVTVNDNPFMKPVEWLSLLLLAGVILVVLPLVLDGFRLNLVGKYLTYAFVALGLVICWGYAGILSLGQGV
FFGLGGYCMAMYLKLEASSIENTKIQSTPGIPDFMDWNQITALPWFWQPFKSLPLTLILAVAVPVLFAMLISFAMFKRRV
GGTYFAIITQAIAAILTILIVGQQGYTGGINGITDLRTLHGWDIRTDHAKVILYFVNGGLLIACILAAQYVKKSKLGRIL
VAMRDKEDRVRFSGYSVAGFKVFAFCFAAGLAAIGGAMFTLQVGFMSPSFVGIVPSIEMVIYAAVGGRLSLFGAVWGTLL
VNWAKTSFSESFPDLWLFGLGALFIAVVLAFPNGLAGIWREHIEPRLTRRVKGLRAPPPAIVPPHGAPAE

Sequences:

>Translated_390_residues
MTNPVQTLTKSVTVNDNPFMKPVEWLSLLLLAGVILVVLPLVLDGFRLNLVGKYLTYAFVALGLVICWGYAGILSLGQGV
FFGLGGYCMAMYLKLEASSIENTKIQSTPGIPDFMDWNQITALPWFWQPFKSLPLTLILAVAVPVLFAMLISFAMFKRRV
GGTYFAIITQAIAAILTILIVGQQGYTGGINGITDLRTLHGWDIRTDHAKVILYFVNGGLLIACILAAQYVKKSKLGRIL
VAMRDKEDRVRFSGYSVAGFKVFAFCFAAGLAAIGGAMFTLQVGFMSPSFVGIVPSIEMVIYAAVGGRLSLFGAVWGTLL
VNWAKTSFSESFPDLWLFGLGALFIAVVLAFPNGLAGIWREHIEPRLTRRVKGLRAPPPAIVPPHGAPAE
>Mature_389_residues
TNPVQTLTKSVTVNDNPFMKPVEWLSLLLLAGVILVVLPLVLDGFRLNLVGKYLTYAFVALGLVICWGYAGILSLGQGVF
FGLGGYCMAMYLKLEASSIENTKIQSTPGIPDFMDWNQITALPWFWQPFKSLPLTLILAVAVPVLFAMLISFAMFKRRVG
GTYFAIITQAIAAILTILIVGQQGYTGGINGITDLRTLHGWDIRTDHAKVILYFVNGGLLIACILAAQYVKKSKLGRILV
AMRDKEDRVRFSGYSVAGFKVFAFCFAAGLAAIGGAMFTLQVGFMSPSFVGIVPSIEMVIYAAVGGRLSLFGAVWGTLLV
NWAKTSFSESFPDLWLFGLGALFIAVVLAFPNGLAGIWREHIEPRLTRRVKGLRAPPPAIVPPHGAPAE

Specific function: Part Of The Binding-Protein-Dependent Transport System For Branched-Chain Amino Acids. Probably Responsible For The Translocation Of The Substrates Across The Membrane. [C]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789865, Length=332, Percent_Identity=24.3975903614458, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42373; Mature: 42242

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPVQTLTKSVTVNDNPFMKPVEWLSLLLLAGVILVVLPLVLDGFRLNLVGKYLTYAFV
CCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ALGLVICWGYAGILSLGQGVFFGLGGYCMAMYLKLEASSIENTKIQSTPGIPDFMDWNQI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCHH
TALPWFWQPFKSLPLTLILAVAVPVLFAMLISFAMFKRRVGGTYFAIITQAIAAILTILI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VGQQGYTGGINGITDLRTLHGWDIRTDHAKVILYFVNGGLLIACILAAQYVKKSKLGRIL
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCEEE
VAMRDKEDRVRFSGYSVAGFKVFAFCFAAGLAAIGGAMFTLQVGFMSPSFVGIVPSIEMV
EEECCCCCCEEECCCEEHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHCCHHHHH
IYAAVGGRLSLFGAVWGTLLVNWAKTSFSESFPDLWLFGLGALFIAVVLAFPNGLAGIWR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EHIEPRLTRRVKGLRAPPPAIVPPHGAPAE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TNPVQTLTKSVTVNDNPFMKPVEWLSLLLLAGVILVVLPLVLDGFRLNLVGKYLTYAFV
CCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ALGLVICWGYAGILSLGQGVFFGLGGYCMAMYLKLEASSIENTKIQSTPGIPDFMDWNQI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCHH
TALPWFWQPFKSLPLTLILAVAVPVLFAMLISFAMFKRRVGGTYFAIITQAIAAILTILI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VGQQGYTGGINGITDLRTLHGWDIRTDHAKVILYFVNGGLLIACILAAQYVKKSKLGRIL
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCEEE
VAMRDKEDRVRFSGYSVAGFKVFAFCFAAGLAAIGGAMFTLQVGFMSPSFVGIVPSIEMV
EEECCCCCCEEECCCEEHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHCCHHHHH
IYAAVGGRLSLFGAVWGTLLVNWAKTSFSESFPDLWLFGLGALFIAVVLAFPNGLAGIWR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EHIEPRLTRRVKGLRAPPPAIVPPHGAPAE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA