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The map label for this gene is fmdA [H]

Identifier: 170751874

GI number: 170751874

Start: 5819477

End: 5820706

Strand: Reverse

Name: fmdA [H]

Synonym: Mrad2831_5506

Alternate gene names: 170751874

Gene position: 5820706-5819477 (Counterclockwise)

Preceding gene: 170751875

Following gene: 170751873

Centisome position: 95.77

GC content: 65.28

Gene sequence:

>1230_bases
ATGCCCGAGACGCTGATCAAGGTCGATCTCACGCAATCGGCCTACGACAACGACATGGTGCACAACCGCTGGCACCCCGA
CATCCCGATGGTCGCCTACGTGAAGCCGGGGGCGGACTTCATCGTCGAGACCTACGACTGGACCGGCGGCTTCATCAAGA
ACAACGATTCCGCCGACGACGTGCGCGACATCGACCTGTCGATCGTGCACTTCCTCTCGGGCCCCATAGGCGTCGAGGGT
GCCGAGCCCGGCGACCTGCTGGTTGTCGACCTCCTCGACATCGGCGCCAAGCCCGAGAGCCAGTGGGGCTTCAACGGATT
CTTCTCGAAGAAGAACGGCGGCGGCTTCCTCACCGAGCACTTCCCGCAGGCCCAGAAGTCGATCTGGGACTTCGAGGGGA
TGTTCACCAAGTCCCGCCACGTCCCGGGCGTGCGCTTCCCCGGCCTGATCCATCCCGGCCTGATCGGCTGCCTGCCCGAT
CCGAAGATGCTGGAGACCTGGAACACCCGCGAGAAGGCGCTCTACGACACCGATCCGGAGCGCGTGCCGGCGCTCGCCAC
CCTCCCCTTCGGCCCGACCGCCCATATGGGCCGCCTGAAGGGCGACGCGAAGGACGCGGCCGCCGCCACTGGTGCCCGCA
CGGTCCCGCCGCGCGAGCACGGCGGCAATTGCGACATCAAGGATCTGTCGCGCGGCTCGAAGATCTACTTCCCGGTCTAC
GTCCCTGGCGCCGGCCTCTCGATGGGCGACCTGCACTTCAGCCAGGGCGACGGCGAGATCACCTTCTGCGGCGCCATCGA
GATGGCCGGCTGGGTGCACCTCAAGGTCGAGCTGATCAAGGACGGCATGGCCAAGTACGGGATCAAGAACCCGATCTTCA
AGCCGTCGCCGATCACGCCGAAATACGACGATCACCTGATCTTCGAGGGCATTTCGGTCGACGAGAGCGGCGGCCAGCAC
TACCTCGACGTCCACATCGCCTACCGGCAGGCCTGCCTGAACGCGATCGAGTACCTGAAGAAGTTCGGCTACTCGGGCGC
GCAGGCCTACTCGATCCTCGGCACGGCGCCGGTCCAGGGGCACATCTCGGGCGTCGTCGACATCCCGAACGCCTGCGCGA
CGCTCTGGATACCGACCAAGATCTTCGAGTTCGACATCAACCCGGGCGCCGACGGACCAACCAAGTTCCTCGACGGCTCG
ATCCAGATGCCGCTCTCGCCGGATCTTTGA

Upstream 100 bases:

>100_bases
TCGACGACGCACTCAAAGAGCTGCTCGCGAGCGGGTGAGAGACGCGCAGCGGCGCGCGGACGGGGGCTGCCCCGGAGAGT
CAGGGAGCTGGAGACACGAG

Downstream 100 bases:

>100_bases
TGCTTCGTTTCCCGGCCGGTCGCGGCTGACGCGACAGGCCCCCTCTCCCGGGCGGGAGAGGGTTGGGGTGAGGGATGCGA
CCTCTCCGGACAGGTCTCGC

Product: formamidase

Products: NA

Alternate protein names: Formamide amidohydrolase [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPETLIKVDLTQSAYDNDMVHNRWHPDIPMVAYVKPGADFIVETYDWTGGFIKNNDSADDVRDIDLSIVHFLSGPIGVEG
AEPGDLLVVDLLDIGAKPESQWGFNGFFSKKNGGGFLTEHFPQAQKSIWDFEGMFTKSRHVPGVRFPGLIHPGLIGCLPD
PKMLETWNTREKALYDTDPERVPALATLPFGPTAHMGRLKGDAKDAAAATGARTVPPREHGGNCDIKDLSRGSKIYFPVY
VPGAGLSMGDLHFSQGDGEITFCGAIEMAGWVHLKVELIKDGMAKYGIKNPIFKPSPITPKYDDHLIFEGISVDESGGQH
YLDVHIAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQGHISGVVDIPNACATLWIPTKIFEFDINPGADGPTKFLDGS
IQMPLSPDL

Sequences:

>Translated_409_residues
MPETLIKVDLTQSAYDNDMVHNRWHPDIPMVAYVKPGADFIVETYDWTGGFIKNNDSADDVRDIDLSIVHFLSGPIGVEG
AEPGDLLVVDLLDIGAKPESQWGFNGFFSKKNGGGFLTEHFPQAQKSIWDFEGMFTKSRHVPGVRFPGLIHPGLIGCLPD
PKMLETWNTREKALYDTDPERVPALATLPFGPTAHMGRLKGDAKDAAAATGARTVPPREHGGNCDIKDLSRGSKIYFPVY
VPGAGLSMGDLHFSQGDGEITFCGAIEMAGWVHLKVELIKDGMAKYGIKNPIFKPSPITPKYDDHLIFEGISVDESGGQH
YLDVHIAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQGHISGVVDIPNACATLWIPTKIFEFDINPGADGPTKFLDGS
IQMPLSPDL
>Mature_408_residues
PETLIKVDLTQSAYDNDMVHNRWHPDIPMVAYVKPGADFIVETYDWTGGFIKNNDSADDVRDIDLSIVHFLSGPIGVEGA
EPGDLLVVDLLDIGAKPESQWGFNGFFSKKNGGGFLTEHFPQAQKSIWDFEGMFTKSRHVPGVRFPGLIHPGLIGCLPDP
KMLETWNTREKALYDTDPERVPALATLPFGPTAHMGRLKGDAKDAAAATGARTVPPREHGGNCDIKDLSRGSKIYFPVYV
PGAGLSMGDLHFSQGDGEITFCGAIEMAGWVHLKVELIKDGMAKYGIKNPIFKPSPITPKYDDHLIFEGISVDESGGQHY
LDVHIAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQGHISGVVDIPNACATLWIPTKIFEFDINPGADGPTKFLDGSI
QMPLSPDL

Specific function: Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. Also acts, more slowly, on acetamide, propanamide and butanamide [H]

COG id: COG2421

COG function: function code C; Predicted acetamidase/formamidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetamidase/formamidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004304 [H]

Pfam domain/function: PF03069 FmdA_AmdA [H]

EC number: =3.5.1.49 [H]

Molecular weight: Translated: 44616; Mature: 44485

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETLIKVDLTQSAYDNDMVHNRWHPDIPMVAYVKPGADFIVETYDWTGGFIKNNDSADD
CCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCEEECCCCCCC
VRDIDLSIVHFLSGPIGVEGAEPGDLLVVDLLDIGAKPESQWGFNGFFSKKNGGGFLTEH
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCCHHHH
FPQAQKSIWDFEGMFTKSRHVPGVRFPGLIHPGLIGCLPDPKMLETWNTREKALYDTDPE
CCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCHH
RVPALATLPFGPTAHMGRLKGDAKDAAAATGARTVPPREHGGNCDIKDLSRGSKIYFPVY
HCCEEEECCCCCCCHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEE
VPGAGLSMGDLHFSQGDGEITFCGAIEMAGWVHLKVELIKDGMAKYGIKNPIFKPSPITP
ECCCCCEECCEEEECCCCCEEEEEEECCCCEEEEEEEEHHCCHHHCCCCCCCCCCCCCCC
KYDDHLIFEGISVDESGGQHYLDVHIAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQG
CCCCEEEEECCEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
HISGVVDIPNACATLWIPTKIFEFDINPGADGPTKFLDGSIQMPLSPDL
CCEEEEECCCCCEEEEEEEEEEEEECCCCCCCCHHHCCCCEECCCCCCC
>Mature Secondary Structure 
PETLIKVDLTQSAYDNDMVHNRWHPDIPMVAYVKPGADFIVETYDWTGGFIKNNDSADD
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCEEECCCCCCC
VRDIDLSIVHFLSGPIGVEGAEPGDLLVVDLLDIGAKPESQWGFNGFFSKKNGGGFLTEH
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCCHHHH
FPQAQKSIWDFEGMFTKSRHVPGVRFPGLIHPGLIGCLPDPKMLETWNTREKALYDTDPE
CCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCHH
RVPALATLPFGPTAHMGRLKGDAKDAAAATGARTVPPREHGGNCDIKDLSRGSKIYFPVY
HCCEEEECCCCCCCHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEE
VPGAGLSMGDLHFSQGDGEITFCGAIEMAGWVHLKVELIKDGMAKYGIKNPIFKPSPITP
ECCCCCEECCEEEECCCCCEEEEEEECCCCEEEEEEEEHHCCHHHCCCCCCCCCCCCCCC
KYDDHLIFEGISVDESGGQHYLDVHIAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQG
CCCCEEEEECCEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
HISGVVDIPNACATLWIPTKIFEFDINPGADGPTKFLDGSIQMPLSPDL
CCEEEEECCCCCEEEEEEEEEEEEECCCCCCCCHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8841393 [H]