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The map label for this gene is tsr [C]

Identifier: 170751326

GI number: 170751326

Start: 5263182

End: 5265128

Strand: Direct

Name: tsr [C]

Synonym: Mrad2831_4944

Alternate gene names: 170751326

Gene position: 5263182-5265128 (Clockwise)

Preceding gene: 170751325

Following gene: 170751334

Centisome position: 86.6

GC content: 72.62

Gene sequence:

>1947_bases
ATGATCACGGGCATCATCGGTGCATTCGCGATCTACCAGCAGGGTGTGATCAGTGACGACCACGCGCTTCAGGAGCGGGT
GGAGCGGGGTGCACAATCGGTCCTGCTGATCGACGGTCATGCCGCGCGCCTCATCGGAGCTGCCGAACGGTACCGGCTCC
AGCCGGATCCCGATCTGATCGTCGCGATGGAGCAGACCCGGCGGGCGATCGAGCAGACCTGCGACAAGTACTTCTCGCTG
GCCATCACGGACGGAGGGCGGAAGCTGTACGACGACATGCGGGAAGCCGCCCGCGCGATGAAGCCGGAGCTGGAGCGCCT
CGCGGCCACGGGTGCGAGCCTGCGTGAGGCCAGGGCGAGACTCTACGAGACCGGCAATACCCTCACGGTCCTTCTCGGAA
ACATGCTCGCGGACGTGCGCGCCCGGGGCGGCGAGGCGATGCTGGCGCGGACCGAGCACATCGAGAATGCGATCCTGCGG
TCCCGCATCGCGTCGGCCCGCTTCGTGATCGGCCTGGATCCGCAGGATCGCAGCGCCTTCGAGCAGCGGGCCGAGCAGGC
TCTGGCGACCCTGGACGCGTTCAAGGACACGCAGGGCGGCGCGGCCTTCGCGCAGCAGCTCAGGGCCGTCCGCGACGCGC
TGATCGCCGCCGCGGCCGGCTTCCGCGCGTACGATCAGGCGGTGGCGTCGGCGAAGGCGACGTTCGAGACCGGGATCAAG
CCCCACGCCGACGCCATCGACCGGCTCGGCGTCGCGCTGCGCGACCGGATCGTGGCCGCCGGCGAGCGGATTTCCCGGGA
CACCGCGCTGGCCGCCTCGCGGGCCCGGTACATCCTGATCGGTCTCGTCGCCGCGGCCCTGCTCCTCGGCGGTGTCCTGG
CCCTCGTGCTGGCCCGCAGCATCATCCGGCCGGTCGCCGGCATGACGGAGGCGATGACGCGGCTGGCCGGCGGCGACCTT
CAGGTCGCGGTGCCGCACCGCGACGCGCGCGACGAGATGGGCGCGATGGCCAAGGCCGTCGACGTCTTCCGCCAGAACGC
CGTCGCCCGGGTCGAGCTGGAGGCGGCGCAGGCCGCCGAGCGGGAGGCCCGCCTGCGCCGGGCCGAGCGGGTCGAGCAGC
GGGTCCAGACCTTCCAGCAGAAGATCGCCGCCTCGCTCGACATCGTCACGGCGGCGACCAGCGAGCTCGACGCGACCGCT
CAGGCGATGACCCAGGTGGCCGAGAATACCAACAGCCAGGCGATGACGTCGAGCTCGGCCGCCGCGCAGACCTCGGCGAA
CGTCCAGACCGTCGCGTCGGCCGCCGAGGAGATGGTCTCCTCTCTCCAGGAGATCGAGCGGCAGGTCGTGCGCTCCAACG
AGGTGGCCGGTCACGCCGCCCACGAGGCCGAGGCGACCAACGCCGCCATGGCGGGCCTGCGCGCGGCCGCCGAGCAGATC
GGCGCCGCCGTGGTCATGATCTCCGGCATCGCGAACCAGACCAACCTGCTGGCCCTCAACGCCACCATCGAGGCGGCGCG
GGCCGGCGAGGCGGGGCGCGGATTCGCGGTCGTGGCCTCCGAGGTGAAGGAGCTCGCCGCGCAGACGGCGCGGGCCACCG
GGGAGATCGGCGGCCAGATCGCCGCGATCCAGGCGTCCTCCGGGCAGGCCGCGGAGGCGATGGCGCAGATCGCCCGCACG
ATCGCCGCCGTGAACGAGATCAGCGGCGCCATCGCGGCGACCGTGGTGCAGCAGACGGCGGCGACCGGCGAGATCTCGCG
CAATGCCGGCGAGGCCGCGCGGGGCACGGAGGGTGTCTCGGCCAGCGTCGCGCGCGTGCTGGCCGCCGCCCGGGAGGCCG
GCAGCGCCGCCGCGCAGGTCCAGAGCGCGGCGTCCGAGCTGGCGACCCAGTCCCTGACGGTCAAGCGCGAGGTCGCCAGC
TTCCTCAGCGATATCCAGGCCGCGTGA

Upstream 100 bases:

>100_bases
CGTCTATCATCCGGCCGAGAAATTGGCTTGTTCTGTGGAAGATACGCCTGTGACAATTGGGATACGCGCGCGCGTCTACG
CGGGATTTGCAGTGCTCGTC

Downstream 100 bases:

>100_bases
GCGGGCGGCCTAGATCGCGGCGGCGGGATCGGTCTCGTCGCCGTCGCGGCTCCGCCGCTCGCGCGGCCGCCGCTCCAGGA
ACGAGCGGCCGATGGCGCGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MITGIIGAFAIYQQGVISDDHALQERVERGAQSVLLIDGHAARLIGAAERYRLQPDPDLIVAMEQTRRAIEQTCDKYFSL
AITDGGRKLYDDMREAARAMKPELERLAATGASLREARARLYETGNTLTVLLGNMLADVRARGGEAMLARTEHIENAILR
SRIASARFVIGLDPQDRSAFEQRAEQALATLDAFKDTQGGAAFAQQLRAVRDALIAAAAGFRAYDQAVASAKATFETGIK
PHADAIDRLGVALRDRIVAAGERISRDTALAASRARYILIGLVAAALLLGGVLALVLARSIIRPVAGMTEAMTRLAGGDL
QVAVPHRDARDEMGAMAKAVDVFRQNAVARVELEAAQAAEREARLRRAERVEQRVQTFQQKIAASLDIVTAATSELDATA
QAMTQVAENTNSQAMTSSSAAAQTSANVQTVASAAEEMVSSLQEIERQVVRSNEVAGHAAHEAEATNAAMAGLRAAAEQI
GAAVVMISGIANQTNLLALNATIEAARAGEAGRGFAVVASEVKELAAQTARATGEIGGQIAAIQASSGQAAEAMAQIART
IAAVNEISGAIAATVVQQTAATGEISRNAGEAARGTEGVSASVARVLAAAREAGSAAAQVQSAASELATQSLTVKREVAS
FLSDIQAA

Sequences:

>Translated_648_residues
MITGIIGAFAIYQQGVISDDHALQERVERGAQSVLLIDGHAARLIGAAERYRLQPDPDLIVAMEQTRRAIEQTCDKYFSL
AITDGGRKLYDDMREAARAMKPELERLAATGASLREARARLYETGNTLTVLLGNMLADVRARGGEAMLARTEHIENAILR
SRIASARFVIGLDPQDRSAFEQRAEQALATLDAFKDTQGGAAFAQQLRAVRDALIAAAAGFRAYDQAVASAKATFETGIK
PHADAIDRLGVALRDRIVAAGERISRDTALAASRARYILIGLVAAALLLGGVLALVLARSIIRPVAGMTEAMTRLAGGDL
QVAVPHRDARDEMGAMAKAVDVFRQNAVARVELEAAQAAEREARLRRAERVEQRVQTFQQKIAASLDIVTAATSELDATA
QAMTQVAENTNSQAMTSSSAAAQTSANVQTVASAAEEMVSSLQEIERQVVRSNEVAGHAAHEAEATNAAMAGLRAAAEQI
GAAVVMISGIANQTNLLALNATIEAARAGEAGRGFAVVASEVKELAAQTARATGEIGGQIAAIQASSGQAAEAMAQIART
IAAVNEISGAIAATVVQQTAATGEISRNAGEAARGTEGVSASVARVLAAAREAGSAAAQVQSAASELATQSLTVKREVAS
FLSDIQAA
>Mature_648_residues
MITGIIGAFAIYQQGVISDDHALQERVERGAQSVLLIDGHAARLIGAAERYRLQPDPDLIVAMEQTRRAIEQTCDKYFSL
AITDGGRKLYDDMREAARAMKPELERLAATGASLREARARLYETGNTLTVLLGNMLADVRARGGEAMLARTEHIENAILR
SRIASARFVIGLDPQDRSAFEQRAEQALATLDAFKDTQGGAAFAQQLRAVRDALIAAAAGFRAYDQAVASAKATFETGIK
PHADAIDRLGVALRDRIVAAGERISRDTALAASRARYILIGLVAAALLLGGVLALVLARSIIRPVAGMTEAMTRLAGGDL
QVAVPHRDARDEMGAMAKAVDVFRQNAVARVELEAAQAAEREARLRRAERVEQRVQTFQQKIAASLDIVTAATSELDATA
QAMTQVAENTNSQAMTSSSAAAQTSANVQTVASAAEEMVSSLQEIERQVVRSNEVAGHAAHEAEATNAAMAGLRAAAEQI
GAAVVMISGIANQTNLLALNATIEAARAGEAGRGFAVVASEVKELAAQTARATGEIGGQIAAIQASSGQAAEAMAQIART
IAAVNEISGAIAATVVQQTAATGEISRNAGEAARGTEGVSASVARVLAAAREAGSAAAQVQSAASELATQSLTVKREVAS
FLSDIQAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=394, Percent_Identity=27.6649746192893, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788194, Length=238, Percent_Identity=32.7731092436975, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787690, Length=380, Percent_Identity=28.4210526315789, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788195, Length=306, Percent_Identity=27.1241830065359, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789453, Length=341, Percent_Identity=27.5659824046921, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 67689; Mature: 67689

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITGIIGAFAIYQQGVISDDHALQERVERGAQSVLLIDGHAARLIGAAERYRLQPDPDLI
CCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCE
VAMEQTRRAIEQTCDKYFSLAITDGGRKLYDDMREAARAMKPELERLAATGASLREARAR
EEHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LYETGNTLTVLLGNMLADVRARGGEAMLARTEHIENAILRSRIASARFVIGLDPQDRSAF
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHH
EQRAEQALATLDAFKDTQGGAAFAQQLRAVRDALIAAAAGFRAYDQAVASAKATFETGIK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PHADAIDRLGVALRDRIVAAGERISRDTALAASRARYILIGLVAAALLLGGVLALVLARS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIRPVAGMTEAMTRLAGGDLQVAVPHRDARDEMGAMAKAVDVFRQNAVARVELEAAQAAE
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHH
REARLRRAERVEQRVQTFQQKIAASLDIVTAATSELDATAQAMTQVAENTNSQAMTSSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHH
AAQTSANVQTVASAAEEMVSSLQEIERQVVRSNEVAGHAAHEAEATNAAMAGLRAAAEQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GAAVVMISGIANQTNLLALNATIEAARAGEAGRGFAVVASEVKELAAQTARATGEIGGQI
CHHHHEEECCCCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
AAIQASSGQAAEAMAQIARTIAAVNEISGAIAATVVQQTAATGEISRNAGEAARGTEGVS
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHH
ASVARVLAAAREAGSAAAQVQSAASELATQSLTVKREVASFLSDIQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITGIIGAFAIYQQGVISDDHALQERVERGAQSVLLIDGHAARLIGAAERYRLQPDPDLI
CCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCE
VAMEQTRRAIEQTCDKYFSLAITDGGRKLYDDMREAARAMKPELERLAATGASLREARAR
EEHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LYETGNTLTVLLGNMLADVRARGGEAMLARTEHIENAILRSRIASARFVIGLDPQDRSAF
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHH
EQRAEQALATLDAFKDTQGGAAFAQQLRAVRDALIAAAAGFRAYDQAVASAKATFETGIK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PHADAIDRLGVALRDRIVAAGERISRDTALAASRARYILIGLVAAALLLGGVLALVLARS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIRPVAGMTEAMTRLAGGDLQVAVPHRDARDEMGAMAKAVDVFRQNAVARVELEAAQAAE
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHH
REARLRRAERVEQRVQTFQQKIAASLDIVTAATSELDATAQAMTQVAENTNSQAMTSSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHH
AAQTSANVQTVASAAEEMVSSLQEIERQVVRSNEVAGHAAHEAEATNAAMAGLRAAAEQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GAAVVMISGIANQTNLLALNATIEAARAGEAGRGFAVVASEVKELAAQTARATGEIGGQI
CHHHHEEECCCCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
AAIQASSGQAAEAMAQIARTIAAVNEISGAIAATVVQQTAATGEISRNAGEAARGTEGVS
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHH
ASVARVLAAAREAGSAAAQVQSAASELATQSLTVKREVASFLSDIQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]