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The map label for this gene is nahR [H]

Identifier: 170751128

GI number: 170751128

Start: 5049441

End: 5050385

Strand: Direct

Name: nahR [H]

Synonym: Mrad2831_4744

Alternate gene names: 170751128

Gene position: 5049441-5050385 (Clockwise)

Preceding gene: 170751122

Following gene: 170751130

Centisome position: 83.08

GC content: 69.31

Gene sequence:

>945_bases
ATGACGATCAAGCACCGTGACCTCGCCGGTATCGACCTGAACCTGGTCGTGGCGCTTGACGCGCTCCTGACCGAGAGCAG
CGTCACGCGCGCCGCAGCGAAGGTCGGCATCACGCAGTCGGCCATGAGCAGCAGCCTCGCCCGCCTGCGCAGGCTCCTCG
GCGACGAGCTCCTAACGCGCACGCCGGACGGCATGCGCCCGACCCCGCGCTCACTCGCCCTCGTCGAGCCGGTCCGAGCG
GCCCTGCGCCAGTTCCAGGGCATCGTCCTCCGGGAGGACGATTTCGACCCCTCGACGGTCGAGCGGTCCTTCACGCTCGC
CATCCCCGGCAGCGTCGAGGTGCGCCTCATCCCGCGCTTGCTCGCTTTCCTTGCAAGCGAGGCGCCTGGCATCCGCCTGC
ACCTGGTCGGCCTCGATTACGCGAGCGTGCTGGGGGACCTCGACGCCGACAGGATCGACATGGCCGTCGGCATGATCTCC
GAGGGCCAGGTCCACCATAAGGTCCGGCCGCTCTATCGCTTCGGCTTCCTGAGCCTGTTCAACCCCCGGCTGCTCGGCGT
CGACGGGCCGCTGTCACTTGACGACTTCGTCCGCTTCCCGCACATCCTGACGTACCTGACCGGCGTCGGCCCGGGGGTGG
TGGACAAGGCGCTCGCGTCGGTAGGCCGGACGCGGAGGCTGGCAGCGACGACGCCACGCTTCGCCACCGTGCCGTTCCAC
GTGCAGGCCGCGCCCCTGATCGCCACAATGGCCGACGAGTTGGCCACGACCTTTGCGGCCCAGCTCGGCTTGGCGACGAG
CCCCGTGCCTGTGCCGACCGAGGAGATCGTCATCTCGATGCTGTGGCACGCCTCCTATGACCGCGATCCGGCCCATCGCT
GGCTGCGGGACGTCATGGTTCGCCTGGGGCGCGAGGCCGGTAGCGCCCGCGAAGAAGCGGTATAA

Upstream 100 bases:

>100_bases
GGTGTCGGTTGGTGCAAGCGGGAAACCCCATGATCGCGCTTGGTCCGACGCCGCATCACTCCGCTGTCGCCGTGGTCGAC
GGCCGCCAGCGAGCCGGGTC

Downstream 100 bases:

>100_bases
CTCGTAGCCTCAAGCCTCTCGGTCCTTGGACCACCTTTACGTTCGGGTGCCTCTGCAGGCAGCAACGGACGCCAATAGAC
AAGTCTGCTATTGGGAGATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTIKHRDLAGIDLNLVVALDALLTESSVTRAAAKVGITQSAMSSSLARLRRLLGDELLTRTPDGMRPTPRSLALVEPVRA
ALRQFQGIVLREDDFDPSTVERSFTLAIPGSVEVRLIPRLLAFLASEAPGIRLHLVGLDYASVLGDLDADRIDMAVGMIS
EGQVHHKVRPLYRFGFLSLFNPRLLGVDGPLSLDDFVRFPHILTYLTGVGPGVVDKALASVGRTRRLAATTPRFATVPFH
VQAAPLIATMADELATTFAAQLGLATSPVPVPTEEIVISMLWHASYDRDPAHRWLRDVMVRLGREAGSAREEAV

Sequences:

>Translated_314_residues
MTIKHRDLAGIDLNLVVALDALLTESSVTRAAAKVGITQSAMSSSLARLRRLLGDELLTRTPDGMRPTPRSLALVEPVRA
ALRQFQGIVLREDDFDPSTVERSFTLAIPGSVEVRLIPRLLAFLASEAPGIRLHLVGLDYASVLGDLDADRIDMAVGMIS
EGQVHHKVRPLYRFGFLSLFNPRLLGVDGPLSLDDFVRFPHILTYLTGVGPGVVDKALASVGRTRRLAATTPRFATVPFH
VQAAPLIATMADELATTFAAQLGLATSPVPVPTEEIVISMLWHASYDRDPAHRWLRDVMVRLGREAGSAREEAV
>Mature_313_residues
TIKHRDLAGIDLNLVVALDALLTESSVTRAAAKVGITQSAMSSSLARLRRLLGDELLTRTPDGMRPTPRSLALVEPVRAA
LRQFQGIVLREDDFDPSTVERSFTLAIPGSVEVRLIPRLLAFLASEAPGIRLHLVGLDYASVLGDLDADRIDMAVGMISE
GQVHHKVRPLYRFGFLSLFNPRLLGVDGPLSLDDFVRFPHILTYLTGVGPGVVDKALASVGRTRRLAATTPRFATVPFHV
QAAPLIATMADELATTFAAQLGLATSPVPVPTEEIVISMLWHASYDRDPAHRWLRDVMVRLGREAGSAREEAV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=294, Percent_Identity=24.8299319727891, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=26.158940397351, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34164; Mature: 34033

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKHRDLAGIDLNLVVALDALLTESSVTRAAAKVGITQSAMSSSLARLRRLLGDELLTR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
TPDGMRPTPRSLALVEPVRAALRQFQGIVLREDDFDPSTVERSFTLAIPGSVEVRLIPRL
CCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHCCEEEEEECCCCHHHHHHHH
LAFLASEAPGIRLHLVGLDYASVLGDLDADRIDMAVGMISEGQVHHKVRPLYRFGFLSLF
HHHHHCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
NPRLLGVDGPLSLDDFVRFPHILTYLTGVGPGVVDKALASVGRTRRLAATTPRFATVPFH
CCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEECCCCEEECCEE
VQAAPLIATMADELATTFAAQLGLATSPVPVPTEEIVISMLWHASYDRDPAHRWLRDVMV
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RLGREAGSAREEAV
HHHHHCCCHHHCCC
>Mature Secondary Structure 
TIKHRDLAGIDLNLVVALDALLTESSVTRAAAKVGITQSAMSSSLARLRRLLGDELLTR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
TPDGMRPTPRSLALVEPVRAALRQFQGIVLREDDFDPSTVERSFTLAIPGSVEVRLIPRL
CCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHCCEEEEEECCCCHHHHHHHH
LAFLASEAPGIRLHLVGLDYASVLGDLDADRIDMAVGMISEGQVHHKVRPLYRFGFLSLF
HHHHHCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
NPRLLGVDGPLSLDDFVRFPHILTYLTGVGPGVVDKALASVGRTRRLAATTPRFATVPFH
CCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEECCCCEEECCEE
VQAAPLIATMADELATTFAAQLGLATSPVPVPTEEIVISMLWHASYDRDPAHRWLRDVMV
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RLGREAGSAREEAV
HHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]