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The map label for this gene is betA [H]

Identifier: 170751117

GI number: 170751117

Start: 5038839

End: 5040545

Strand: Direct

Name: betA [H]

Synonym: Mrad2831_4733

Alternate gene names: 170751117

Gene position: 5038839-5040545 (Clockwise)

Preceding gene: 170751116

Following gene: 170751118

Centisome position: 82.91

GC content: 70.77

Gene sequence:

>1707_bases
ATGAACGCCTTGCCCGAAACGGTCGACGTGTTGATCGTCGGCGGGGGCTCTGCCGGCTGCGTGATGGCCCACCGGCTCTC
CGCCGACCCGCGGCGCCGGGTGCTCCTCGTCGAAGCCGGCATCGATACACCGCCGGGCCGGGTGCCGGCGGAGATTCTCG
ACAGCTATCCGATGCCGCTGTTCCATGGCGACACCTACATCTGGCCGGGGCTCGACGCGGCGGTCACCCGCGACTCCCGC
GGTCGCATGCGGCGGCGGGCCTACGAGCAGGGCCGGGTGATGGGCGGCTCGTCCAGCATCAACGTCCAGGCGGCCAACCG
CGGGCTGCCCCGCGATTACGAGGCCTGGGCCGCGCTCGGCGCCGAGGGCTGGGCCTGGGACGACGTACTGCCGTATTTCC
GCAGGCTCGAGACCGACCTCGATTGCGGCGGTCCGCTGCACGGCCATGATGGGCCGCTCCCGATCCGGCGCATCCTGGAG
CCCGCATGGCCTCCCTTCGCCCATGCGGTCGCCCGCGCCTTCGATGCGACGGGGCTGCCCCGGCGCGTCGATCAGAACGG
CGAGTTCGAGGACGGGATCTTCCCGCCGGCCTTCTCCAACCGGGACGACGCGCGGGTCTCGGCCGCCGCCGCGTATTTGG
ACGTGGGTACGCGGGCCCGGCCGAATCTCACCATCGCCGCCGGCCTCGAGGTCCGCTCGCTGGTGATGGACGGGCGCCGC
GCGACCGGGGCCGTGCTGCGGCGGGGCGACGGATCCGAGCAACAAGTGAGCGCCGCCTCCGTAGTCCTGTGCGCCGGCGC
TCTTCAATCGCCGGTGCTCCTCCTGCGTGCCGGGATCGGCCCGGGCGATGCGCTCTCCGCCTGCGGGATACCCGTCCGGC
TGGATCGTTCGGGCGTCGGCGAGAACCTGCGGGACCATCCCGCTTTGACGATGGCCCAGGTCCTTCCCCGCCCGCTCCGG
CTGCCCGAGACCTTCCGGCGCGCGAGCTTGCTGGCCCTGCGCTATTCGTCCGGCCATCCCGAAGGCTGCGCCTCTGATAT
GTATCTCACTGCCTCCGCCCGTGCCGGCTGGCACGCCCTCGGCGGACGCCTTGCGCTCTACTTCCTCTGGGTGAACCAAC
CGCACTCGGTCGGGCGCCTGCGCCTCGATCCGGCGAACCCGTCCGGCCCGCCCGACATCGATCTCGGCCTGCTCTCGGAT
CGCCGCGATCTCGAACGCCTCGCCTCGGGGATTCGGCTGCTCAGCGACCTCGTGGTCTCGCCCACGCTGAACCCCCGCTC
CGACGACCTCTTCCCCGCGAACTATTCGCCGCTGATCCGCCGGTTGAGCGCCGTCTCCCCTCGCAACCGGCGGCTCACCG
GCCTCCTCGCCCCCGTGTTCGATGCACCGGCCATGCTGCGCGCCCCGCTGCTGCGCGCCGTCCTAGGCGGCCACGCTTGG
GCGACAGTGCTTCAGGACGATGGCGCTCTCGACGACTTTGTCCGGGACAACGTCTTCGGGGTCTGGCATGCGAGCGGTAC
GTGCCGCATGGGCCGGGCCGACGATCCCGGCGCGGTGGTCAATCCGGGGGGACGCGTCATCGGAACCGACAACCTGTCCG
TCGCCGACGCATCGGTGATGCCCCGCCTTCCTAGCGCAAACACGAACGTCCCGACCTTGATGATTGCGGAAAAGATCGCG
GAGAGGATGATGGTGGAGATGGGATGA

Upstream 100 bases:

>100_bases
ATGAAATTCAAGCGCATCCGTGTTCCCGGCGAGGCCGAGGTCGATCTCGACGCGGTGCTCGCGTCCGGCGCCGACTGGCG
CGCGGCGATCGGCTGATCCC

Downstream 100 bases:

>100_bases
TCCCTCTCGACACATTCGGCGCCTTTGCGGTGGCCGACCTACGGCTGGAATACCGTTTCGTCGGTCCGCAGCCGGACTTG
GCGCCGACGCTGGTGTTGCT

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MNALPETVDVLIVGGGSAGCVMAHRLSADPRRRVLLVEAGIDTPPGRVPAEILDSYPMPLFHGDTYIWPGLDAAVTRDSR
GRMRRRAYEQGRVMGGSSSINVQAANRGLPRDYEAWAALGAEGWAWDDVLPYFRRLETDLDCGGPLHGHDGPLPIRRILE
PAWPPFAHAVARAFDATGLPRRVDQNGEFEDGIFPPAFSNRDDARVSAAAAYLDVGTRARPNLTIAAGLEVRSLVMDGRR
ATGAVLRRGDGSEQQVSAASVVLCAGALQSPVLLLRAGIGPGDALSACGIPVRLDRSGVGENLRDHPALTMAQVLPRPLR
LPETFRRASLLALRYSSGHPEGCASDMYLTASARAGWHALGGRLALYFLWVNQPHSVGRLRLDPANPSGPPDIDLGLLSD
RRDLERLASGIRLLSDLVVSPTLNPRSDDLFPANYSPLIRRLSAVSPRNRRLTGLLAPVFDAPAMLRAPLLRAVLGGHAW
ATVLQDDGALDDFVRDNVFGVWHASGTCRMGRADDPGAVVNPGGRVIGTDNLSVADASVMPRLPSANTNVPTLMIAEKIA
ERMMVEMG

Sequences:

>Translated_568_residues
MNALPETVDVLIVGGGSAGCVMAHRLSADPRRRVLLVEAGIDTPPGRVPAEILDSYPMPLFHGDTYIWPGLDAAVTRDSR
GRMRRRAYEQGRVMGGSSSINVQAANRGLPRDYEAWAALGAEGWAWDDVLPYFRRLETDLDCGGPLHGHDGPLPIRRILE
PAWPPFAHAVARAFDATGLPRRVDQNGEFEDGIFPPAFSNRDDARVSAAAAYLDVGTRARPNLTIAAGLEVRSLVMDGRR
ATGAVLRRGDGSEQQVSAASVVLCAGALQSPVLLLRAGIGPGDALSACGIPVRLDRSGVGENLRDHPALTMAQVLPRPLR
LPETFRRASLLALRYSSGHPEGCASDMYLTASARAGWHALGGRLALYFLWVNQPHSVGRLRLDPANPSGPPDIDLGLLSD
RRDLERLASGIRLLSDLVVSPTLNPRSDDLFPANYSPLIRRLSAVSPRNRRLTGLLAPVFDAPAMLRAPLLRAVLGGHAW
ATVLQDDGALDDFVRDNVFGVWHASGTCRMGRADDPGAVVNPGGRVIGTDNLSVADASVMPRLPSANTNVPTLMIAEKIA
ERMMVEMG
>Mature_568_residues
MNALPETVDVLIVGGGSAGCVMAHRLSADPRRRVLLVEAGIDTPPGRVPAEILDSYPMPLFHGDTYIWPGLDAAVTRDSR
GRMRRRAYEQGRVMGGSSSINVQAANRGLPRDYEAWAALGAEGWAWDDVLPYFRRLETDLDCGGPLHGHDGPLPIRRILE
PAWPPFAHAVARAFDATGLPRRVDQNGEFEDGIFPPAFSNRDDARVSAAAAYLDVGTRARPNLTIAAGLEVRSLVMDGRR
ATGAVLRRGDGSEQQVSAASVVLCAGALQSPVLLLRAGIGPGDALSACGIPVRLDRSGVGENLRDHPALTMAQVLPRPLR
LPETFRRASLLALRYSSGHPEGCASDMYLTASARAGWHALGGRLALYFLWVNQPHSVGRLRLDPANPSGPPDIDLGLLSD
RRDLERLASGIRLLSDLVVSPTLNPRSDDLFPANYSPLIRRLSAVSPRNRRLTGLLAPVFDAPAMLRAPLLRAVLGGHAW
ATVLQDDGALDDFVRDNVFGVWHASGTCRMGRADDPGAVVNPGGRVIGTDNLSVADASVMPRLPSANTNVPTLMIAEKIA
ERMMVEMG

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=585, Percent_Identity=31.4529914529915, Blast_Score=224, Evalue=2e-58,
Organism=Escherichia coli, GI1786503, Length=584, Percent_Identity=29.2808219178082, Blast_Score=196, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17532301, Length=329, Percent_Identity=34.3465045592705, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI17137792, Length=591, Percent_Identity=30.1184433164129, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24642048, Length=594, Percent_Identity=30.8080808080808, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24642037, Length=608, Percent_Identity=30.9210526315789, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24642051, Length=615, Percent_Identity=26.9918699186992, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24642055, Length=313, Percent_Identity=38.9776357827476, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24642059, Length=607, Percent_Identity=28.171334431631, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24642042, Length=600, Percent_Identity=29.1666666666667, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI18859993, Length=616, Percent_Identity=27.9220779220779, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45551458, Length=614, Percent_Identity=28.1758957654723, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24642039, Length=322, Percent_Identity=33.2298136645963, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24642035, Length=306, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI18859995, Length=341, Percent_Identity=31.3782991202346, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24650267, Length=319, Percent_Identity=33.8557993730408, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45549471, Length=310, Percent_Identity=34.1935483870968, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24642057, Length=311, Percent_Identity=28.9389067524116, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 60973; Mature: 60973

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPETVDVLIVGGGSAGCVMAHRLSADPRRRVLLVEAGIDTPPGRVPAEILDSYPMPL
CCCCCCEEEEEEECCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCE
FHGDTYIWPGLDAAVTRDSRGRMRRRAYEQGRVMGGSSSINVQAANRGLPRDYEAWAALG
EECCEEECCCCCHHHCCCHHHHHHHHHHHHCCEECCCCCEEEEECCCCCCCCHHHHHHHC
AEGWAWDDVLPYFRRLETDLDCGGPLHGHDGPLPIRRILEPAWPPFAHAVARAFDATGLP
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCC
RRVDQNGEFEDGIFPPAFSNRDDARVSAAAAYLDVGTRARPNLTIAAGLEVRSLVMDGRR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCC
ATGAVLRRGDGSEQQVSAASVVLCAGALQSPVLLLRAGIGPGDALSACGIPVRLDRSGVG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHCCCCEEECCCCCC
ENLRDHPALTMAQVLPRPLRLPETFRRASLLALRYSSGHPEGCASDMYLTASARAGWHAL
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
GGRLALYFLWVNQPHSVGRLRLDPANPSGPPDIDLGLLSDRRDLERLASGIRLLSDLVVS
CCEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHC
PTLNPRSDDLFPANYSPLIRRLSAVSPRNRRLTGLLAPVFDAPAMLRAPLLRAVLGGHAW
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHEEHHHHHCCHHHHHHHHHHHHHCCCCE
ATVLQDDGALDDFVRDNVFGVWHASGTCRMGRADDPGAVVNPGGRVIGTDNLSVADASVM
EEEECCCCCHHHHHHCCEEEEEECCCEEECCCCCCCCCEECCCCCEEECCCCCCCCHHHC
PRLPSANTNVPTLMIAEKIAERMMVEMG
CCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNALPETVDVLIVGGGSAGCVMAHRLSADPRRRVLLVEAGIDTPPGRVPAEILDSYPMPL
CCCCCCEEEEEEECCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCE
FHGDTYIWPGLDAAVTRDSRGRMRRRAYEQGRVMGGSSSINVQAANRGLPRDYEAWAALG
EECCEEECCCCCHHHCCCHHHHHHHHHHHHCCEECCCCCEEEEECCCCCCCCHHHHHHHC
AEGWAWDDVLPYFRRLETDLDCGGPLHGHDGPLPIRRILEPAWPPFAHAVARAFDATGLP
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCC
RRVDQNGEFEDGIFPPAFSNRDDARVSAAAAYLDVGTRARPNLTIAAGLEVRSLVMDGRR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCC
ATGAVLRRGDGSEQQVSAASVVLCAGALQSPVLLLRAGIGPGDALSACGIPVRLDRSGVG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHCCCCEEECCCCCC
ENLRDHPALTMAQVLPRPLRLPETFRRASLLALRYSSGHPEGCASDMYLTASARAGWHAL
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHEEEEEECCCCCCCCCCCEEEEECCCCCHHHH
GGRLALYFLWVNQPHSVGRLRLDPANPSGPPDIDLGLLSDRRDLERLASGIRLLSDLVVS
CCEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHC
PTLNPRSDDLFPANYSPLIRRLSAVSPRNRRLTGLLAPVFDAPAMLRAPLLRAVLGGHAW
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHEEHHHHHCCHHHHHHHHHHHHHCCCCE
ATVLQDDGALDDFVRDNVFGVWHASGTCRMGRADDPGAVVNPGGRVIGTDNLSVADASVM
EEEECCCCCHHHHHHCCEEEEEECCCEEECCCCCCCCCEECCCCCEEECCCCCCCCHHHC
PRLPSANTNVPTLMIAEKIAERMMVEMG
CCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA