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The map label for this gene is caiD [C]

Identifier: 170751111

GI number: 170751111

Start: 5032831

End: 5033637

Strand: Direct

Name: caiD [C]

Synonym: Mrad2831_4727

Alternate gene names: 170751111

Gene position: 5032831-5033637 (Clockwise)

Preceding gene: 170751110

Following gene: 170751112

Centisome position: 82.81

GC content: 67.91

Gene sequence:

>807_bases
ATGACGAGCGACACCCACACCATCGACCCGCGCCTGACGAACCTCGACGGGTTCCGCGTCGAGATCGACTCGGAGCGCGA
GCGCGCCGACGTGATCCTGGCGCGGCCGCCCATGAACGTCATTGCGATGCCCCAGCGCGATGAGATCCGCAAGGTCTTCG
AGGCGCTGGACGAGGATCCCCGCGTGCGGGTCATCGTCCTGCGGGCGGAGGGCGAGCACTTCTCGTCGGGGGGCTACATC
AAGGGCTTCCTCGACGCCTCGCCCGAGCACGTTTCGAAGCTCGCCTGGAACATAGCGGCGCCGGCCCGCTGCTCGAAGCC
CGTCATCGCCGCCAACCGGGGCTACACGTTCGGTGTCGGCTTCGAGATCTCGCTGGCCTGCGATTTCCGCATCGTCTCCG
AGACCTGCCGCTACGCGCTTCCCGAACAGAAGCTCGGCCAGATTCCCGGCTCCGGCGGCTCGGCCCGGCTCCAGAAGATC
GTCGGCATCACCCGGACCAAGGATATCGTGATGCGCTCCAAGCGCATCCCCGGGCGGCAGGCCCTCGACTGGGGCATCGC
CACCGAATGCGTACCCGATGCGGACCTGGAGAAGGCCACCGACGCCCTCGTGGAGGAACTGCGCGCCTTCTCGCCCATCG
CCCAGCGCACCGCCAAGAAGCTCCTCAACGACACCGAGGACGCGAGCCTGTCCATCGCCATCGAGCTCGAAGGACACTGC
TACAGCCGCCTTCGTCAGGCCGACGACTTCCGCGAGGGCGTCGAGGCGTTCCACGCCAAGCGCGCGCCGCGCTTCACCGG
CTCATAG

Upstream 100 bases:

>100_bases
GAGTACGTCCTGGAAGGCGGGGCCGAGCCCCATGCCGAAGGTCACGAGGCTGCCTGACGGTCCCGCCCCCACTCCGAATC
ACAAGCGAGAGACCAAACCC

Downstream 100 bases:

>100_bases
TCCGGCCGCGCCGGGGGGGCTGCCGAGCGGTTCCCCCCATCCTGTGACGCCTACCGCACCGCTTCGATCCCGCCCAGGCG
GGAAACGACGACGCACGCCC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTSDTHTIDPRLTNLDGFRVEIDSERERADVILARPPMNVIAMPQRDEIRKVFEALDEDPRVRVIVLRAEGEHFSSGGYI
KGFLDASPEHVSKLAWNIAAPARCSKPVIAANRGYTFGVGFEISLACDFRIVSETCRYALPEQKLGQIPGSGGSARLQKI
VGITRTKDIVMRSKRIPGRQALDWGIATECVPDADLEKATDALVEELRAFSPIAQRTAKKLLNDTEDASLSIAIELEGHC
YSRLRQADDFREGVEAFHAKRAPRFTGS

Sequences:

>Translated_268_residues
MTSDTHTIDPRLTNLDGFRVEIDSERERADVILARPPMNVIAMPQRDEIRKVFEALDEDPRVRVIVLRAEGEHFSSGGYI
KGFLDASPEHVSKLAWNIAAPARCSKPVIAANRGYTFGVGFEISLACDFRIVSETCRYALPEQKLGQIPGSGGSARLQKI
VGITRTKDIVMRSKRIPGRQALDWGIATECVPDADLEKATDALVEELRAFSPIAQRTAKKLLNDTEDASLSIAIELEGHC
YSRLRQADDFREGVEAFHAKRAPRFTGS
>Mature_267_residues
TSDTHTIDPRLTNLDGFRVEIDSERERADVILARPPMNVIAMPQRDEIRKVFEALDEDPRVRVIVLRAEGEHFSSGGYIK
GFLDASPEHVSKLAWNIAAPARCSKPVIAANRGYTFGVGFEISLACDFRIVSETCRYALPEQKLGQIPGSGGSARLQKIV
GITRTKDIVMRSKRIPGRQALDWGIATECVPDADLEKATDALVEELRAFSPIAQRTAKKLLNDTEDASLSIAIELEGHCY
SRLRQADDFREGVEAFHAKRAPRFTGS

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=236, Percent_Identity=30.9322033898305, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4502327, Length=239, Percent_Identity=32.2175732217573, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI68989263, Length=172, Percent_Identity=30.8139534883721, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI150378541, Length=141, Percent_Identity=29.0780141843972, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI45643119, Length=218, Percent_Identity=25.2293577981651, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI260275230, Length=218, Percent_Identity=25.2293577981651, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI260274832, Length=218, Percent_Identity=25.2293577981651, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI70995211, Length=226, Percent_Identity=23.4513274336283, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI221142681, Length=253, Percent_Identity=33.596837944664, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787659, Length=240, Percent_Identity=30.4166666666667, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788597, Length=248, Percent_Identity=29.4354838709677, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788682, Length=227, Percent_Identity=26.431718061674, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787660, Length=167, Percent_Identity=32.3353293413174, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790281, Length=160, Percent_Identity=30, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082183, Length=237, Percent_Identity=24.4725738396624, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=204, Percent_Identity=30.8823529411765, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=28.8065843621399, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17554946, Length=252, Percent_Identity=27.3809523809524, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17534483, Length=255, Percent_Identity=27.843137254902, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=265, Percent_Identity=24.5283018867925, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560910, Length=141, Percent_Identity=27.6595744680851, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=181, Percent_Identity=28.1767955801105, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI20129971, Length=257, Percent_Identity=26.4591439688716, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24653477, Length=257, Percent_Identity=26.4591439688716, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=30.6201550387597, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI19920382, Length=211, Percent_Identity=27.4881516587678, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29708; Mature: 29577

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDTHTIDPRLTNLDGFRVEIDSERERADVILARPPMNVIAMPQRDEIRKVFEALDEDP
CCCCCCCCCCEEECCCCEEEEECCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHCCCC
RVRVIVLRAEGEHFSSGGYIKGFLDASPEHVSKLAWNIAAPARCSKPVIAANRGYTFGVG
CEEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEECCCCEEEECC
FEISLACDFRIVSETCRYALPEQKLGQIPGSGGSARLQKIVGITRTKDIVMRSKRIPGRQ
EEEEEEECHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCH
ALDWGIATECVPDADLEKATDALVEELRAFSPIAQRTAKKLLNDTEDASLSIAIELEGHC
HHCCCCHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEEECCHH
YSRLRQADDFREGVEAFHAKRAPRFTGS
HHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSDTHTIDPRLTNLDGFRVEIDSERERADVILARPPMNVIAMPQRDEIRKVFEALDEDP
CCCCCCCCCEEECCCCEEEEECCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHCCCC
RVRVIVLRAEGEHFSSGGYIKGFLDASPEHVSKLAWNIAAPARCSKPVIAANRGYTFGVG
CEEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEECCCCEEEECC
FEISLACDFRIVSETCRYALPEQKLGQIPGSGGSARLQKIVGITRTKDIVMRSKRIPGRQ
EEEEEEECHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCH
ALDWGIATECVPDADLEKATDALVEELRAFSPIAQRTAKKLLNDTEDASLSIAIELEGHC
HHCCCCHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEEECCHH
YSRLRQADDFREGVEAFHAKRAPRFTGS
HHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA