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The map label for this gene is torS [H]

Identifier: 170751098

GI number: 170751098

Start: 5016589

End: 5018175

Strand: Direct

Name: torS [H]

Synonym: Mrad2831_4714

Alternate gene names: 170751098

Gene position: 5016589-5018175 (Clockwise)

Preceding gene: 170751093

Following gene: 170751099

Centisome position: 82.54

GC content: 67.67

Gene sequence:

>1587_bases
ATGTCGTTGCTGCGCAAGACTCTGGCTTGGCGCCACTCCCTGGTCGCGAAGCTCGGTCTCATGGTGCTCCTCTTTATGGC
CGCGACGGAGGGCGCCCGCCTCCTCAGCCTGGATCGGCTCGAACATGCCGACGCGCTCTCCCGCGAGATGCACCACCGCT
GGCTAGAGCGCATCCGGATCCTCGGGAGTCTGAACCACGGGATCTCGGACGCGCGCACCGCGGAGGCCGAAATCCTTCTC
GGCCCGGATCCCGCGGACCGCCCCGATCGCCTGGCGTCGCTGCAGCGCGTATCCGCCCATCTCGCGGGAATGATGACACG
CTACGCGGAGCTGCTCAGGCGAGACGAGGATCGGAGCGAGGTCGTGCGGCTGCAAGACCTATGGCGCGCGCACGCAGCCG
TGGCGGAGCGCGTGGCCGCGCTGAGCCGGGACGGCGAGGCCGACCAAGCAATCCTGCTGTTCAACGGCGAGTCGAAGACC
ACCTTCGACGCGGCCCGTAACGCCGCCTTCACCCTGACGCTCGTGACAGAAGCGCGCGCCGAGGCCGACCGCGGCCGAGC
GGCCGCGGCCATCGCGGCAGCTCAGGACTGGGTCTCCGACCTGATGCTTGGGACCCTGGCCCTGTTCTTCGCCATCACGG
TCTACGTCTGGCGCGCCATCTCGCAGCCGCTCCTGCGGCTGGCTGATCGTATGCGGCGTCTCGCGGATTATGAGACCGAC
TTCGCGCTCCCCGACGAGAAGCGGCCAGACGAGATTGGGGCGATGGCGGGAGCGCTTGCGGTGTTCCGGAGCAATACCAC
CGAGCTTCTTGAGTCGCGCAAGCGCCTAGCCATACAATCCGGCGCGCTAAGCACCGCCTTGCAGAAGGAGCGGGCGCTCG
CCGTTGAGCAGCGCAACTTCATAACGACGGTCTCGCATGAATTCCGCACGCCGCTGATGGCGATCGACGGGAACGCGCAG
CGGCTGATCGCGATCAAGGACCGGGCCAAGCCGGGCGACATCGCCGATCGGGCACACCGCATCCGGTCCGCCGTGTTCCG
GATCGCGAGCCTGATGTCGGGCCTATCGCGGGCGCTGGAGGATACCGGCGGAAACCTCCGTCCGCGCATGCGCCGCTTCG
ATCTTGCCGCGATGCTGCGGTCGTTGTGCCGGTACTATCGCGAGATTGGGATGGGTGGTGAGTTGGTCGACGACATGTCG
GATGCATCGCTGGAGATCGTCGGCGATCCCGACCTTCTGCATCTGGCCGTCAGCAACCTTCTCTCGAACGGGTTCAAGTA
TGCGTCGGACAGCGACCCCGTCCGACTGCGGGCATACCCGTCCGGCGCCGGCGTCGAGATCGTCGTCGAGGACGAGGGCG
TGGGCATCCCGCGCGGCGAGATCGGACGCATCCGCGAGCGCTACTACCGGGCGAGCAACGTCGGCACGATACCGGGCACG
GGGATCGGGCTGAGCCTCGTGGAGGAGATCGCACGCCGCCATGGTGGCCGCCTCGTCATCGAGAGCGAAGAGGGTCGCGG
AACCCGTGCTATGCTGGCGCTGCCGCGGGACGGGGCGCTGTCATCCCCGGAGTCGGAGCATGCCTAG

Upstream 100 bases:

>100_bases
GTGGCCCCCGGCGTCATCCTGTGAAATCTGACAGGCTTACATCGGACAGGCCGGGCCTAAGCCTTCGAAGCCCGGCCACT
GGATCCGCGGGGGGATCGCC

Downstream 100 bases:

>100_bases
GATACTCTGCGTTGAGGACGACGCGGAAACGGCGAGCCTGCTCGCGGAAGCCCTGGTTGACCTCGGCTACACGGTGGAAC
GCGCCTCGGACGGGGAGGCG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MSLLRKTLAWRHSLVAKLGLMVLLFMAATEGARLLSLDRLEHADALSREMHHRWLERIRILGSLNHGISDARTAEAEILL
GPDPADRPDRLASLQRVSAHLAGMMTRYAELLRRDEDRSEVVRLQDLWRAHAAVAERVAALSRDGEADQAILLFNGESKT
TFDAARNAAFTLTLVTEARAEADRGRAAAAIAAAQDWVSDLMLGTLALFFAITVYVWRAISQPLLRLADRMRRLADYETD
FALPDEKRPDEIGAMAGALAVFRSNTTELLESRKRLAIQSGALSTALQKERALAVEQRNFITTVSHEFRTPLMAIDGNAQ
RLIAIKDRAKPGDIADRAHRIRSAVFRIASLMSGLSRALEDTGGNLRPRMRRFDLAAMLRSLCRYYREIGMGGELVDDMS
DASLEIVGDPDLLHLAVSNLLSNGFKYASDSDPVRLRAYPSGAGVEIVVEDEGVGIPRGEIGRIRERYYRASNVGTIPGT
GIGLSLVEEIARRHGGRLVIESEEGRGTRAMLALPRDGALSSPESEHA

Sequences:

>Translated_528_residues
MSLLRKTLAWRHSLVAKLGLMVLLFMAATEGARLLSLDRLEHADALSREMHHRWLERIRILGSLNHGISDARTAEAEILL
GPDPADRPDRLASLQRVSAHLAGMMTRYAELLRRDEDRSEVVRLQDLWRAHAAVAERVAALSRDGEADQAILLFNGESKT
TFDAARNAAFTLTLVTEARAEADRGRAAAAIAAAQDWVSDLMLGTLALFFAITVYVWRAISQPLLRLADRMRRLADYETD
FALPDEKRPDEIGAMAGALAVFRSNTTELLESRKRLAIQSGALSTALQKERALAVEQRNFITTVSHEFRTPLMAIDGNAQ
RLIAIKDRAKPGDIADRAHRIRSAVFRIASLMSGLSRALEDTGGNLRPRMRRFDLAAMLRSLCRYYREIGMGGELVDDMS
DASLEIVGDPDLLHLAVSNLLSNGFKYASDSDPVRLRAYPSGAGVEIVVEDEGVGIPRGEIGRIRERYYRASNVGTIPGT
GIGLSLVEEIARRHGGRLVIESEEGRGTRAMLALPRDGALSSPESEHA
>Mature_527_residues
SLLRKTLAWRHSLVAKLGLMVLLFMAATEGARLLSLDRLEHADALSREMHHRWLERIRILGSLNHGISDARTAEAEILLG
PDPADRPDRLASLQRVSAHLAGMMTRYAELLRRDEDRSEVVRLQDLWRAHAAVAERVAALSRDGEADQAILLFNGESKTT
FDAARNAAFTLTLVTEARAEADRGRAAAAIAAAQDWVSDLMLGTLALFFAITVYVWRAISQPLLRLADRMRRLADYETDF
ALPDEKRPDEIGAMAGALAVFRSNTTELLESRKRLAIQSGALSTALQKERALAVEQRNFITTVSHEFRTPLMAIDGNAQR
LIAIKDRAKPGDIADRAHRIRSAVFRIASLMSGLSRALEDTGGNLRPRMRRFDLAAMLRSLCRYYREIGMGGELVDDMSD
ASLEIVGDPDLLHLAVSNLLSNGFKYASDSDPVRLRAYPSGAGVEIVVEDEGVGIPRGEIGRIRERYYRASNVGTIPGTG
IGLSLVEEIARRHGGRLVIESEEGRGTRAMLALPRDGALSSPESEHA

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates torR via a four-step phosphorelay. When TMAO is removed,

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=352, Percent_Identity=28.6931818181818, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=29.8642533936652, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=27.1111111111111, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=29.6943231441048, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=25.8771929824561, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=241, Percent_Identity=27.3858921161826, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=249, Percent_Identity=27.3092369477912, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789149, Length=340, Percent_Identity=22.9411764705882, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=270, Percent_Identity=23.7037037037037, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=307, Percent_Identity=25.0814332247557, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790551, Length=340, Percent_Identity=25.2941176470588, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=23.8095238095238, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014302
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58183; Mature: 58052

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLRKTLAWRHSLVAKLGLMVLLFMAATEGARLLSLDRLEHADALSREMHHRWLERIRI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLNHGISDARTAEAEILLGPDPADRPDRLASLQRVSAHLAGMMTRYAELLRRDEDRSE
HHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VVRLQDLWRAHAAVAERVAALSRDGEADQAILLFNGESKTTFDAARNAAFTLTLVTEARA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCEEEEEEEEHHHH
EADRGRAAAAIAAAQDWVSDLMLGTLALFFAITVYVWRAISQPLLRLADRMRRLADYETD
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FALPDEKRPDEIGAMAGALAVFRSNTTELLESRKRLAIQSGALSTALQKERALAVEQRNF
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ITTVSHEFRTPLMAIDGNAQRLIAIKDRAKPGDIADRAHRIRSAVFRIASLMSGLSRALE
HHHHHHHHCCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTGGNLRPRMRRFDLAAMLRSLCRYYREIGMGGELVDDMSDASLEIVGDPDLLHLAVSNL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCHHHHHHHHHH
LSNGFKYASDSDPVRLRAYPSGAGVEIVVEDEGVGIPRGEIGRIRERYYRASNVGTIPGT
HHCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
GIGLSLVEEIARRHGGRLVIESEEGRGTRAMLALPRDGALSSPESEHA
CCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SLLRKTLAWRHSLVAKLGLMVLLFMAATEGARLLSLDRLEHADALSREMHHRWLERIRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLNHGISDARTAEAEILLGPDPADRPDRLASLQRVSAHLAGMMTRYAELLRRDEDRSE
HHHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VVRLQDLWRAHAAVAERVAALSRDGEADQAILLFNGESKTTFDAARNAAFTLTLVTEARA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCEEEEEEEEHHHH
EADRGRAAAAIAAAQDWVSDLMLGTLALFFAITVYVWRAISQPLLRLADRMRRLADYETD
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FALPDEKRPDEIGAMAGALAVFRSNTTELLESRKRLAIQSGALSTALQKERALAVEQRNF
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ITTVSHEFRTPLMAIDGNAQRLIAIKDRAKPGDIADRAHRIRSAVFRIASLMSGLSRALE
HHHHHHHHCCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTGGNLRPRMRRFDLAAMLRSLCRYYREIGMGGELVDDMSDASLEIVGDPDLLHLAVSNL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCHHHHHHHHHH
LSNGFKYASDSDPVRLRAYPSGAGVEIVVEDEGVGIPRGEIGRIRERYYRASNVGTIPGT
HHCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
GIGLSLVEEIARRHGGRLVIESEEGRGTRAMLALPRDGALSSPESEHA
CCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]