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The map label for this gene is tsr [C]

Identifier: 170751042

GI number: 170751042

Start: 4951992

End: 4954091

Strand: Reverse

Name: tsr [C]

Synonym: Mrad2831_4653

Alternate gene names: 170751042

Gene position: 4954091-4951992 (Counterclockwise)

Preceding gene: 170751043

Following gene: 170751041

Centisome position: 81.51

GC content: 75.76

Gene sequence:

>2100_bases
ATGAGTCGCTGGCTGGGACGCTTCTCGATCCGGACCTTGCTGTGCCTGGTGATCGTCATCATGGCCTGCATGGCGCTGGG
CAACGCGGTCAGGTCGCTCGTCGACGCGCGGGCGCAGGCGGCGCGCGCGGCCCGCGCCGTGACCCTGACGGAGGCGAGTC
AGGGCCTCCTCAGGGCGATCCTGCCGCTGCGGCTCGAGCGCGGATCGTCCCTCGCCCTCGGGGGTGAGGCGCCCGCGGAC
GCGAAGACCCTGTCGACCGTCGCGGACAGCCGGCAGGCGCTGACCGAGAATTACCGCCGGGCTCAGCGCAGCCTGAGCGA
TCTGGCCGAGCCGGCGGTCAGCGCGACGCTCGACCGCCTGACCACGGCGCAGGAGGCGATGGCGGCCCTGCGCCCCCGCA
TCGACGAGGCCCTCCGGCTGCCGAAGGCGCAGCGCGACCCGGCGCTGCGGGAGGCCGCGATGGCCGCCTTCCAGGACCTG
CTCGAGGCGCTGACGGCCACGCTGAAGGCGGTCGACGCGTCCATTCCCCGCTCCGATCCCGCCCTGCAGCGCTATCTCGC
CCTCAAGCAGGCGGCCTGGGACACGCGCGTGGCCAGCGGCAACGTCGCGGTGCGGGTGCAGAGCTCGCTGGTCGCCGGCG
CGTCGTGGTCCCTGCCCGAGACGATCGCGGCGGCCGAGGAGCGGACCGAACTTCTGGCGGCGTGGCGGCGCACGACCGAG
GCCGCGACCGGCGTCTCGGAGGCGGTGCGGGCCGCGTTCGAGCGGGCGAAGGCCAGCAATTTCGAGGGCGAGACCAGGGC
CATCGCGCAGGCGGTCTTCGACGCGCTCAGCACGCACACGCCCCCGCGCCACTCGTTCGCGGAGCTGCGCGACCGCAACA
CCGAGAACCAGCGCTCCCTCGTGGCCCTCTGCGACGCGGCCCTGGACGCGATGGTGGCGCGCGCCGAGGCCCTCGCCGAC
GCGGCCCGGAGCGACGTCGCGCGCAGCGGGGCGGCGCTGCTGGCGGTGATCCTGCTGGTGGCCCTCGGCCTGTGGACCCT
GTTCGGCGGCGTGCTGCGCCCGCTCCGGGCGCTGACCGCGACGATGCGGGCGCTGGCCGACGGGGACGCCTCCGTCACAG
TTTCGGCGCGCACCTACCGCAACGAGATCGGCGCGATGGCGCGGGCCGTCCAGGTGTTCAAGGACAACCTCATCCGCAGC
CGGCAGCTCGAGTCCGAGGCCGCGGAGGCGCGGCTGGCGGCGGAGGCGCGGCGCCGGTCCGACCTGCGGGCGATGGCCGA
GCGGTTCGAGCGGACGGTCGGCGGCATCATCGCCCAGGTCTCGGACTCGGCCACCGCGCTGCAGGGTACGGCCCAGACCA
TGACGGCCACCGCGACCCGGACCGCCAGCCAGTCCAGCACGGTGGCGGCCGCCGCCGAGGAGGCCGCCGCCAACGTCAGC
ACCGTGGCGGCGGCGGCCGAGGAACTCGGCGCCTCCGTGGAGGAGATCGGCCGGCAGGTCGAGGGATCGACCAGGCTCGC
CCAGGGGGCAGTCTCGGAGGCCGGGCAGACGGGCGCGCTGGTCCGCGACCTGAGCGGCGCGGTCGCGCGGATCGGCGACG
TGGTCGGGCTGATCGCGGCGATCGCCGGGCAGACCAATCTGCTGGCGCTCAACGCCACCATCGAGGCCGCCCGCGCCGGC
GAGGCGGGCCGGGGCTTCGCGGTCGTCGCCGGCGAGGTGAAGGCGCTGGCGGCGCAGACCGCCCGGGCGACCGAGGAGAT
CGCCGGCCAGATCGCCGGCATCCAGGGCGCGACCGGCGGGGCCGTCGCGGCGATCGGCGCGATCACGGGGCGGATCCAGG
AGATCAGCGGCGTGGCGAGCGCGATCGCGGCGGCGGTGGAGGAGCAGGGATCGGCCACCCGGGAGATCGTCCGCAACGTC
GGGCAGGCGGCCGTCGGCACCGGCGCGGTGACCAGCACCATTCTGGGGGTCGCCGGGGCCGCCGAGGAGACCGGCCGGGC
GGCCGCCGCGGTACTCGCGGCGGCGTCCGCGCTGTCGCGGCAATCCGAGACGCTCACCGCCGAGGTCGCGCGCTTCCTCG
ACAGCGTCCGGGCCGCCTGA

Upstream 100 bases:

>100_bases
AAAATATTTTAATCTTTATTACGGACAGCGCGATCGCTCGATTGCTCGACGAAACCTGACGTTATAGGAGCGAGCATCGC
AGATCCTGAGATTTTCTCCC

Downstream 100 bases:

>100_bases
CCGAACGGTGCCGGGGCCCGCGGGCCTCCGCCCCGATCTCGCCCGTTTAGGGGAGTCTTACGGCTCGCGCGCTACAGCGT
ACGCAACGGGCGGGCGCAAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MSRWLGRFSIRTLLCLVIVIMACMALGNAVRSLVDARAQAARAARAVTLTEASQGLLRAILPLRLERGSSLALGGEAPAD
AKTLSTVADSRQALTENYRRAQRSLSDLAEPAVSATLDRLTTAQEAMAALRPRIDEALRLPKAQRDPALREAAMAAFQDL
LEALTATLKAVDASIPRSDPALQRYLALKQAAWDTRVASGNVAVRVQSSLVAGASWSLPETIAAAEERTELLAAWRRTTE
AATGVSEAVRAAFERAKASNFEGETRAIAQAVFDALSTHTPPRHSFAELRDRNTENQRSLVALCDAALDAMVARAEALAD
AARSDVARSGAALLAVILLVALGLWTLFGGVLRPLRALTATMRALADGDASVTVSARTYRNEIGAMARAVQVFKDNLIRS
RQLESEAAEARLAAEARRRSDLRAMAERFERTVGGIIAQVSDSATALQGTAQTMTATATRTASQSSTVAAAAEEAAANVS
TVAAAAEELGASVEEIGRQVEGSTRLAQGAVSEAGQTGALVRDLSGAVARIGDVVGLIAAIAGQTNLLALNATIEAARAG
EAGRGFAVVAGEVKALAAQTARATEEIAGQIAGIQGATGGAVAAIGAITGRIQEISGVASAIAAAVEEQGSATREIVRNV
GQAAVGTGAVTSTILGVAGAAEETGRAAAAVLAAASALSRQSETLTAEVARFLDSVRAA

Sequences:

>Translated_699_residues
MSRWLGRFSIRTLLCLVIVIMACMALGNAVRSLVDARAQAARAARAVTLTEASQGLLRAILPLRLERGSSLALGGEAPAD
AKTLSTVADSRQALTENYRRAQRSLSDLAEPAVSATLDRLTTAQEAMAALRPRIDEALRLPKAQRDPALREAAMAAFQDL
LEALTATLKAVDASIPRSDPALQRYLALKQAAWDTRVASGNVAVRVQSSLVAGASWSLPETIAAAEERTELLAAWRRTTE
AATGVSEAVRAAFERAKASNFEGETRAIAQAVFDALSTHTPPRHSFAELRDRNTENQRSLVALCDAALDAMVARAEALAD
AARSDVARSGAALLAVILLVALGLWTLFGGVLRPLRALTATMRALADGDASVTVSARTYRNEIGAMARAVQVFKDNLIRS
RQLESEAAEARLAAEARRRSDLRAMAERFERTVGGIIAQVSDSATALQGTAQTMTATATRTASQSSTVAAAAEEAAANVS
TVAAAAEELGASVEEIGRQVEGSTRLAQGAVSEAGQTGALVRDLSGAVARIGDVVGLIAAIAGQTNLLALNATIEAARAG
EAGRGFAVVAGEVKALAAQTARATEEIAGQIAGIQGATGGAVAAIGAITGRIQEISGVASAIAAAVEEQGSATREIVRNV
GQAAVGTGAVTSTILGVAGAAEETGRAAAAVLAAASALSRQSETLTAEVARFLDSVRAA
>Mature_698_residues
SRWLGRFSIRTLLCLVIVIMACMALGNAVRSLVDARAQAARAARAVTLTEASQGLLRAILPLRLERGSSLALGGEAPADA
KTLSTVADSRQALTENYRRAQRSLSDLAEPAVSATLDRLTTAQEAMAALRPRIDEALRLPKAQRDPALREAAMAAFQDLL
EALTATLKAVDASIPRSDPALQRYLALKQAAWDTRVASGNVAVRVQSSLVAGASWSLPETIAAAEERTELLAAWRRTTEA
ATGVSEAVRAAFERAKASNFEGETRAIAQAVFDALSTHTPPRHSFAELRDRNTENQRSLVALCDAALDAMVARAEALADA
ARSDVARSGAALLAVILLVALGLWTLFGGVLRPLRALTATMRALADGDASVTVSARTYRNEIGAMARAVQVFKDNLIRSR
QLESEAAEARLAAEARRRSDLRAMAERFERTVGGIIAQVSDSATALQGTAQTMTATATRTASQSSTVAAAAEEAAANVST
VAAAAEELGASVEEIGRQVEGSTRLAQGAVSEAGQTGALVRDLSGAVARIGDVVGLIAAIAGQTNLLALNATIEAARAGE
AGRGFAVVAGEVKALAAQTARATEEIAGQIAGIQGATGGAVAAIGAITGRIQEISGVASAIAAAVEEQGSATREIVRNVG
QAAVGTGAVTSTILGVAGAAEETGRAAAAVLAAASALSRQSETLTAEVARFLDSVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=318, Percent_Identity=30.188679245283, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787690, Length=321, Percent_Identity=31.1526479750779, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1788195, Length=223, Percent_Identity=31.8385650224215, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788194, Length=184, Percent_Identity=36.9565217391304, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1789453, Length=122, Percent_Identity=40.1639344262295, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72001; Mature: 71870

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRWLGRFSIRTLLCLVIVIMACMALGNAVRSLVDARAQAARAARAVTLTEASQGLLRAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLRLERGSSLALGGEAPADAKTLSTVADSRQALTENYRRAQRSLSDLAEPAVSATLDRL
HHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTAQEAMAALRPRIDEALRLPKAQRDPALREAAMAAFQDLLEALTATLKAVDASIPRSDP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ALQRYLALKQAAWDTRVASGNVAVRVQSSLVAGASWSLPETIAAAEERTELLAAWRRTTE
HHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AATGVSEAVRAAFERAKASNFEGETRAIAQAVFDALSTHTPPRHSFAELRDRNTENQRSL
HHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHH
VALCDAALDAMVARAEALADAARSDVARSGAALLAVILLVALGLWTLFGGVLRPLRALTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMRALADGDASVTVSARTYRNEIGAMARAVQVFKDNLIRSRQLESEAAEARLAAEARRRS
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRAMAERFERTVGGIIAQVSDSATALQGTAQTMTATATRTASQSSTVAAAAEEAAANVS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TVAAAAEELGASVEEIGRQVEGSTRLAQGAVSEAGQTGALVRDLSGAVARIGDVVGLIAA
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAGQTNLLALNATIEAARAGEAGRGFAVVAGEVKALAAQTARATEEIAGQIAGIQGATGG
HCCCCCEEEEECHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AVAAIGAITGRIQEISGVASAIAAAVEEQGSATREIVRNVGQAAVGTGAVTSTILGVAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
AEETGRAAAAVLAAASALSRQSETLTAEVARFLDSVRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRWLGRFSIRTLLCLVIVIMACMALGNAVRSLVDARAQAARAARAVTLTEASQGLLRAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLRLERGSSLALGGEAPADAKTLSTVADSRQALTENYRRAQRSLSDLAEPAVSATLDRL
HHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTAQEAMAALRPRIDEALRLPKAQRDPALREAAMAAFQDLLEALTATLKAVDASIPRSDP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ALQRYLALKQAAWDTRVASGNVAVRVQSSLVAGASWSLPETIAAAEERTELLAAWRRTTE
HHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AATGVSEAVRAAFERAKASNFEGETRAIAQAVFDALSTHTPPRHSFAELRDRNTENQRSL
HHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHH
VALCDAALDAMVARAEALADAARSDVARSGAALLAVILLVALGLWTLFGGVLRPLRALTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMRALADGDASVTVSARTYRNEIGAMARAVQVFKDNLIRSRQLESEAAEARLAAEARRRS
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRAMAERFERTVGGIIAQVSDSATALQGTAQTMTATATRTASQSSTVAAAAEEAAANVS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
TVAAAAEELGASVEEIGRQVEGSTRLAQGAVSEAGQTGALVRDLSGAVARIGDVVGLIAA
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAGQTNLLALNATIEAARAGEAGRGFAVVAGEVKALAAQTARATEEIAGQIAGIQGATGG
HCCCCCEEEEECHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AVAAIGAITGRIQEISGVASAIAAAVEEQGSATREIVRNVGQAAVGTGAVTSTILGVAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
AEETGRAAAAVLAAASALSRQSETLTAEVARFLDSVRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]