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The map label for this gene is dhmA1 [H]

Identifier: 170750961

GI number: 170750961

Start: 4867232

End: 4868281

Strand: Direct

Name: dhmA1 [H]

Synonym: Mrad2831_4572

Alternate gene names: 170750961

Gene position: 4867232-4868281 (Clockwise)

Preceding gene: 170750959

Following gene: 170750962

Centisome position: 80.08

GC content: 74.1

Gene sequence:

>1050_bases
ATGGCCCGCGAGACCGATCCCGACACATCCGCCTGGAGCCGCCGCCGCCTCCTGAAGAGCGCGGTAGCCACCGCCGCCCT
CGCCGAACTCGGCGTCGGCGGGACCGCGCGGGCGCAGGGTGCCCCGGCCCCCGGCGCCCCGGTCCCCGGCGTCATGCCGG
GCGTCCTGAAGCAGGTCGAGGCCGGCGTGCTCGACGTCGGCTACGTCGAGGCCGGTCCCGCCGACGGGCCGGCGGTCATC
CTGCTTCACGGCTGGCCCTACGACATCCACGCCTTCGCGGAGGTCGTGCCGATCCTCGCGGCGGCCGGGCACCGGGTGAT
CGTGCCGTACCTGCGTGGCTACGGCACCACCCGCTTCCTGGCATCGGACACGGTCCGGAACGGCGAGCAGGCGGCACTCG
CGGTGGACGTCATCGCCCTGATGGACGCCCTGAAGATCCCCCAGGCCATCCTGGGCGGCTTCGACTGGGGCGCGCGGACG
GCCGACATCGTCGCGGCGCTGTGGCCGGAGCGGTGCCGGGCGCTGGTGGCGGTCAGCGGCTACCTGATCGGCAACCAGGA
GGCCGGCAAGAAGCCGCTCCCGCCGCGGGCCGAGCTGTCCTGGTGGTACCAGTTCTACTTCGCCACCAGCCGGGGGCGGG
CCGGCTACGAGGCCTACCGCGCCGACTTCGCCAGGCTGATCTGGCAGACCGCCTCGCCGCGCTGGCGCTTCGACGACGCC
ACCTTCGCGCGGAGCGCCCCGGCCCTCGACAACCCGGATCACGTCAGCATCGTCATCCACAATTACCGCTGGCGGATGGG
CCTCGCCGAAGGCGAGCGCCAGTACGACGCGCTGGAGCGCCGCCTCGCTGAGGCGCCCACGATCGGCGTGCCGGCCATCA
CCCTGGAGGGCGACGCGAACGGCGCCCCGCATCCGGACCCCGCCAGCTACGCGGCCAAGTTTACCGGGCGCTACGCGCAC
CGGCTGATCACCGGCGGGATCGGCCACAACCTGCCGCAGGAGGCCCCGCGCGCCTTCGCGCAGGCCGTGATCGACGCGGC
CGCGGCCTGA

Upstream 100 bases:

>100_bases
ATGGGCCTCTGAAGGTGTCCTCAAGGCCCTCTCAAAGCGCGGTGTCGAACATCGGGATAGGTTTCGCTCCATCGAAGACT
TTCCGACGAGGGAGCCGTCC

Downstream 100 bases:

>100_bases
CCGCGCCGGCGCGGCCGGGTCATCCCCGGAAACACGACCATCCCGAGACGATGACGGAGGTTGCCATGCGGTTCCTGGCT
GTCGCGCTGCCGGCCCTGCT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MARETDPDTSAWSRRRLLKSAVATAALAELGVGGTARAQGAPAPGAPVPGVMPGVLKQVEAGVLDVGYVEAGPADGPAVI
LLHGWPYDIHAFAEVVPILAAAGHRVIVPYLRGYGTTRFLASDTVRNGEQAALAVDVIALMDALKIPQAILGGFDWGART
ADIVAALWPERCRALVAVSGYLIGNQEAGKKPLPPRAELSWWYQFYFATSRGRAGYEAYRADFARLIWQTASPRWRFDDA
TFARSAPALDNPDHVSIVIHNYRWRMGLAEGERQYDALERRLAEAPTIGVPAITLEGDANGAPHPDPASYAAKFTGRYAH
RLITGGIGHNLPQEAPRAFAQAVIDAAAA

Sequences:

>Translated_349_residues
MARETDPDTSAWSRRRLLKSAVATAALAELGVGGTARAQGAPAPGAPVPGVMPGVLKQVEAGVLDVGYVEAGPADGPAVI
LLHGWPYDIHAFAEVVPILAAAGHRVIVPYLRGYGTTRFLASDTVRNGEQAALAVDVIALMDALKIPQAILGGFDWGART
ADIVAALWPERCRALVAVSGYLIGNQEAGKKPLPPRAELSWWYQFYFATSRGRAGYEAYRADFARLIWQTASPRWRFDDA
TFARSAPALDNPDHVSIVIHNYRWRMGLAEGERQYDALERRLAEAPTIGVPAITLEGDANGAPHPDPASYAAKFTGRYAH
RLITGGIGHNLPQEAPRAFAQAVIDAAAA
>Mature_348_residues
ARETDPDTSAWSRRRLLKSAVATAALAELGVGGTARAQGAPAPGAPVPGVMPGVLKQVEAGVLDVGYVEAGPADGPAVIL
LHGWPYDIHAFAEVVPILAAAGHRVIVPYLRGYGTTRFLASDTVRNGEQAALAVDVIALMDALKIPQAILGGFDWGARTA
DIVAALWPERCRALVAVSGYLIGNQEAGKKPLPPRAELSWWYQFYFATSRGRAGYEAYRADFARLIWQTASPRWRFDDAT
FARSAPALDNPDHVSIVIHNYRWRMGLAEGERQYDALERRLAEAPTIGVPAITLEGDANGAPHPDPASYAAKFTGRYAHR
LITGGIGHNLPQEAPRAFAQAVIDAAAA

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=167, Percent_Identity=29.940119760479, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 37347; Mature: 37215

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARETDPDTSAWSRRRLLKSAVATAALAELGVGGTARAQGAPAPGAPVPGVMPGVLKQVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AGVLDVGYVEAGPADGPAVILLHGWPYDIHAFAEVVPILAAAGHRVIVPYLRGYGTTRFL
CCCEEECCEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCEEE
ASDTVRNGEQAALAVDVIALMDALKIPQAILGGFDWGARTADIVAALWPERCRALVAVSG
HHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHC
YLIGNQEAGKKPLPPRAELSWWYQFYFATSRGRAGYEAYRADFARLIWQTASPRWRFDDA
EEEECCCCCCCCCCCCCHHEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
TFARSAPALDNPDHVSIVIHNYRWRMGLAEGERQYDALERRLAEAPTIGVPAITLEGDAN
HHHCCCCCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCC
GAPHPDPASYAAKFTGRYAHRLITGGIGHNLPQEAPRAFAQAVIDAAAA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARETDPDTSAWSRRRLLKSAVATAALAELGVGGTARAQGAPAPGAPVPGVMPGVLKQVE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AGVLDVGYVEAGPADGPAVILLHGWPYDIHAFAEVVPILAAAGHRVIVPYLRGYGTTRFL
CCCEEECCEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCEEE
ASDTVRNGEQAALAVDVIALMDALKIPQAILGGFDWGARTADIVAALWPERCRALVAVSG
HHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHC
YLIGNQEAGKKPLPPRAELSWWYQFYFATSRGRAGYEAYRADFARLIWQTASPRWRFDDA
EEEECCCCCCCCCCCCCHHEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
TFARSAPALDNPDHVSIVIHNYRWRMGLAEGERQYDALERRLAEAPTIGVPAITLEGDAN
HHHCCCCCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCC
GAPHPDPASYAAKFTGRYAHRLITGGIGHNLPQEAPRAFAQAVIDAAAA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]