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The map label for this gene is dppC [H]

Identifier: 170750865

GI number: 170750865

Start: 4756646

End: 4757617

Strand: Direct

Name: dppC [H]

Synonym: Mrad2831_4476

Alternate gene names: 170750865

Gene position: 4756646-4757617 (Clockwise)

Preceding gene: 170750864

Following gene: 170750866

Centisome position: 78.26

GC content: 69.65

Gene sequence:

>972_bases
ATGAGCGGACGTGACATCGACGCGGGCGACGCCCCGCCGGTCCCACTGCCGGAGGCGAAGCCCTCCCGCCTCGCGCGCTG
GCGCGAGTCCGACCTGCTGGCGAACTTTCTGCGCTCGAAAACCGCTGTGGCGGCGCTGGTCGCCACCGTGCTGATGGTCG
GGCTCGCCTTCGCGTCGCCGTGGATCGCGCCGCAGAACCCCTACGACCCGGCCCAGCTCGACCTGATCAACTCCAACCTG
CCGCCGATCTGGCAGGCGGACGGGCAGGCGCCGTACTATCTCGGCACCGACGACCAGGGCCGGGACGTGCTCTCGGCGGT
GCTGTACGGCCTGCGCCTGTCGCTGATCGTCGGCGTGCTCGGGGTGGTGACCTCCGGGATCCTCGGCATCGCGCTCGGCC
TGATCGCCGGCTACGCGGGCGGCTTCCTCGACACGCTGATCATGCGGGTCGCCGACGTGCAGCTCACCTTCCCGGCGATC
CTGATCGCCCTGGTGGTCGACGGCGTCGCCAAGGCGAGCTTCGGCAGCGCGCTGGATGTCGGGCCGCTGATCGGGCTGAT
CGTGGTCTCGATCGGCCTGTCCTTCTGGGTGCAGTACGCCCGGACCGTGCGCTCCTCCGTGATGGTCGAGAAGGGCAAGG
ACTACGTCCAGGCGGCGCGGCTGATCGGCCTGTCGCCGCCGGTGATCATGGTCCGCCACGTCCTGCCGAACGTCACCGGC
CCGGTCTTCGTGATCGCGACGATCAACCTCGCGCTCGCGATCATCACCGAGGCGACCCTGTCGTTCCTCGGCACCGGCCT
GCCCGAGACCATGCCGTCGCTGGGCACCCTGATCCGCACCGGCAACCGGTTCCTGTTCTCCGGCGAGTGGTGGATCGTCG
CCTTCCCGGGTCTGGCGCTGGCCGGCCTCGTCATCGCCATCAACCTCCTGGGGGATTGGCTGCGCGACGCGCTCAATCCG
AAGCTGCAATGA

Upstream 100 bases:

>100_bases
CTGATCTTCGTGACCATCAATCTCGTGGTCGACATCCTCTACACGGTGGTGGACCCGCGCCTGCGGCTGCCCGCCGGGCG
GGCGGCGTGAGGAGCGACCG

Downstream 100 bases:

>100_bases
GCGACACCGTTCTCTCCGTGCGCGACCTGACGGTCGCCTTCGACACCCGCCGCGGGCCGCTCACCGCCATCGACCGGGTC
TCGTTCGACATCGGCCGCGG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSGRDIDAGDAPPVPLPEAKPSRLARWRESDLLANFLRSKTAVAALVATVLMVGLAFASPWIAPQNPYDPAQLDLINSNL
PPIWQADGQAPYYLGTDDQGRDVLSAVLYGLRLSLIVGVLGVVTSGILGIALGLIAGYAGGFLDTLIMRVADVQLTFPAI
LIALVVDGVAKASFGSALDVGPLIGLIVVSIGLSFWVQYARTVRSSVMVEKGKDYVQAARLIGLSPPVIMVRHVLPNVTG
PVFVIATINLALAIITEATLSFLGTGLPETMPSLGTLIRTGNRFLFSGEWWIVAFPGLALAGLVIAINLLGDWLRDALNP
KLQ

Sequences:

>Translated_323_residues
MSGRDIDAGDAPPVPLPEAKPSRLARWRESDLLANFLRSKTAVAALVATVLMVGLAFASPWIAPQNPYDPAQLDLINSNL
PPIWQADGQAPYYLGTDDQGRDVLSAVLYGLRLSLIVGVLGVVTSGILGIALGLIAGYAGGFLDTLIMRVADVQLTFPAI
LIALVVDGVAKASFGSALDVGPLIGLIVVSIGLSFWVQYARTVRSSVMVEKGKDYVQAARLIGLSPPVIMVRHVLPNVTG
PVFVIATINLALAIITEATLSFLGTGLPETMPSLGTLIRTGNRFLFSGEWWIVAFPGLALAGLVIAINLLGDWLRDALNP
KLQ
>Mature_322_residues
SGRDIDAGDAPPVPLPEAKPSRLARWRESDLLANFLRSKTAVAALVATVLMVGLAFASPWIAPQNPYDPAQLDLINSNLP
PIWQADGQAPYYLGTDDQGRDVLSAVLYGLRLSLIVGVLGVVTSGILGIALGLIAGYAGGFLDTLIMRVADVQLTFPAIL
IALVVDGVAKASFGSALDVGPLIGLIVVSIGLSFWVQYARTVRSSVMVEKGKDYVQAARLIGLSPPVIMVRHVLPNVTGP
VFVIATINLALAIITEATLSFLGTGLPETMPSLGTLIRTGNRFLFSGEWWIVAFPGLALAGLVIAINLLGDWLRDALNPK
LQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=288, Percent_Identity=43.0555555555556, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787054, Length=309, Percent_Identity=33.3333333333333, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787760, Length=302, Percent_Identity=31.7880794701987, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787498, Length=292, Percent_Identity=33.2191780821918, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789889, Length=256, Percent_Identity=33.59375, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788505, Length=229, Percent_Identity=31.8777292576419, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787549, Length=303, Percent_Identity=30.3630363036304, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34170; Mature: 34038

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRDIDAGDAPPVPLPEAKPSRLARWRESDLLANFLRSKTAVAALVATVLMVGLAFASP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WIAPQNPYDPAQLDLINSNLPPIWQADGQAPYYLGTDDQGRDVLSAVLYGLRLSLIVGVL
CCCCCCCCCCHHHEEECCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
GVVTSGILGIALGLIAGYAGGFLDTLIMRVADVQLTFPAILIALVVDGVAKASFGSALDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GPLIGLIVVSIGLSFWVQYARTVRSSVMVEKGKDYVQAARLIGLSPPVIMVRHVLPNVTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCC
PVFVIATINLALAIITEATLSFLGTGLPETMPSLGTLIRTGNRFLFSGEWWIVAFPGLAL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCEEEEECCHHHH
AGLVIAINLLGDWLRDALNPKLQ
HHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SGRDIDAGDAPPVPLPEAKPSRLARWRESDLLANFLRSKTAVAALVATVLMVGLAFASP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
WIAPQNPYDPAQLDLINSNLPPIWQADGQAPYYLGTDDQGRDVLSAVLYGLRLSLIVGVL
CCCCCCCCCCHHHEEECCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
GVVTSGILGIALGLIAGYAGGFLDTLIMRVADVQLTFPAILIALVVDGVAKASFGSALDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GPLIGLIVVSIGLSFWVQYARTVRSSVMVEKGKDYVQAARLIGLSPPVIMVRHVLPNVTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCC
PVFVIATINLALAIITEATLSFLGTGLPETMPSLGTLIRTGNRFLFSGEWWIVAFPGLAL
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCEEEEECCHHHH
AGLVIAINLLGDWLRDALNPKLQ
HHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]