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The map label for this gene is fae-hps [H]

Identifier: 170750856

GI number: 170750856

Start: 4746054

End: 4746602

Strand: Reverse

Name: fae-hps [H]

Synonym: Mrad2831_4467

Alternate gene names: 170750856

Gene position: 4746602-4746054 (Counterclockwise)

Preceding gene: 170750857

Following gene: 170750855

Centisome position: 78.1

GC content: 65.94

Gene sequence:

>549_bases
ATGAACGAGCGCATCATCCTGCGGGCCGGGGAGGCCCTGGTGGCGGGCGGACCGCCCAACACCGCCTCCGAGCCCGAGGT
CATCATCGGCGAGCTCGACGGGCCGGTCGGCACCGCCCTGGCCACGCTCACCGGCGATCAGGTCGTCGGGCACAGCCGCG
TCTTCGCCCTGCTCAACACCGACATCATGGTCCGCCCGGTCACCCTGTGCGTGTCCAAGGTCAGCGTCACCGAGAGCAAG
TACACCTCGATCCTGATGGGCACCGTCCAGTTCGCCATCGCCAACGGCGTCCTGGATGCCGTGCGCGCCGGCTACATCCC
CAAGCACAAGGCCAACGACCTCGGCATCATCTGCTCGGTCTGGCTCAGCCCCGGCGTCATCGAGGCCCAGCACGTCGACC
ACAAGGCCCTGTTCGACATCCAGCGCAGGGGCATGACCGAGGCCATCCGCAAGGCCATGACCAACGAGCCCTCGATCGAC
TGGCTCCTCGAGAACCAGGACAAGATCACCCACAAGTACTACCAGATGGGCCTCGACGGAAAAATCTGA

Upstream 100 bases:

>100_bases
TCGGGCGGGAGCCGCGCCCGCGTCGACAGGCCCGGCGGGCCGGTGTTAGGTGCCGCGCCGTCGGGCAGAGCGGGATCGCC
CGACCTTGACGAGGGACAGC

Downstream 100 bases:

>100_bases
GCGCCCGGCCCCGCGGCGATCGCCCGCCCGCCGCCGCGGCCCCGGCCGGCGACGGGCGGGCGGGACGCGCACGATTCCGC
GGGAGGGCACGGCCAAGCCT

Product: formaldehyde-activating protein

Products: NA

Alternate protein names: Formaldehyde-activating enzyme; Fae; 3-hexulose-6-phosphate synthase; HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MNERIILRAGEALVAGGPPNTASEPEVIIGELDGPVGTALATLTGDQVVGHSRVFALLNTDIMVRPVTLCVSKVSVTESK
YTSILMGTVQFAIANGVLDAVRAGYIPKHKANDLGIICSVWLSPGVIEAQHVDHKALFDIQRRGMTEAIRKAMTNEPSID
WLLENQDKITHKYYQMGLDGKI

Sequences:

>Translated_182_residues
MNERIILRAGEALVAGGPPNTASEPEVIIGELDGPVGTALATLTGDQVVGHSRVFALLNTDIMVRPVTLCVSKVSVTESK
YTSILMGTVQFAIANGVLDAVRAGYIPKHKANDLGIICSVWLSPGVIEAQHVDHKALFDIQRRGMTEAIRKAMTNEPSID
WLLENQDKITHKYYQMGLDGKI
>Mature_182_residues
MNERIILRAGEALVAGGPPNTASEPEVIIGELDGPVGTALATLTGDQVVGHSRVFALLNTDIMVRPVTLCVSKVSVTESK
YTSILMGTVQFAIANGVLDAVRAGYIPKHKANDLGIICSVWLSPGVIEAQHVDHKALFDIQRRGMTEAIRKAMTNEPSID
WLLENQDKITHKYYQMGLDGKI

Specific function: Catalyzes the formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate [H]

COG id: COG1795

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR020868
- InterPro:   IPR014826
- InterPro:   IPR001754
- InterPro:   IPR020568
- InterPro:   IPR011060 [H]

Pfam domain/function: PF08714 Fae; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 19707; Mature: 19707

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERIILRAGEALVAGGPPNTASEPEVIIGELDGPVGTALATLTGDQVVGHSRVFALLNT
CCCEEEEEECCEEEECCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCHHCHHHEEEEECC
DIMVRPVTLCVSKVSVTESKYTSILMGTVQFAIANGVLDAVRAGYIPKHKANDLGIICSV
CEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
WLSPGVIEAQHVDHKALFDIQRRGMTEAIRKAMTNEPSIDWLLENQDKITHKYYQMGLDG
ECCCCEEEHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCC
KI
CC
>Mature Secondary Structure
MNERIILRAGEALVAGGPPNTASEPEVIIGELDGPVGTALATLTGDQVVGHSRVFALLNT
CCCEEEEEECCEEEECCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCHHCHHHEEEEECC
DIMVRPVTLCVSKVSVTESKYTSILMGTVQFAIANGVLDAVRAGYIPKHKANDLGIICSV
CEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
WLSPGVIEAQHVDHKALFDIQRRGMTEAIRKAMTNEPSIDWLLENQDKITHKYYQMGLDG
ECCCCEEEHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCC
KI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA