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The map label for this gene is gph [C]

Identifier: 170750834

GI number: 170750834

Start: 4728520

End: 4729224

Strand: Direct

Name: gph [C]

Synonym: Mrad2831_4445

Alternate gene names: 170750834

Gene position: 4728520-4729224 (Clockwise)

Preceding gene: 170750833

Following gene: 170750839

Centisome position: 77.8

GC content: 78.3

Gene sequence:

>705_bases
TTGCCTGCGCCCCCGCCCGCGGCCCCGTCGCGCTTCGACGCCGTGCTCCTGGATCTCGACGGCACCCTCGTCGACAGCCT
GGCCGACCTCCGGACAGCCCTGAACGAAACCCTGGCGCGGGAGGGCCTGCCGCCGGTCGGTGCCGCCGCGATGCGGGCGA
TGGTGGGCGACGGCGCGGTGGCGCTGCTGCGGCGCGCCCTGCGGGCCTCGGGCGGCGATCCGGGGCGGGCGCCGGCGCTG
TTGCCGGCCTTCCTGGCGGTGTACGAGCCGCTCGCGGCCGCCGGCACGCCCCTGTTCCCCGGCGCCGCCGCGGCGGTCCG
CGATCTCCGGACGGCCGGCTACGCCCTGGCGATCGTCACCAACAAGCCGGCCCGCGCCACCGGCCTGATCCTGGACGCGG
TGGGGCTGGCGCCGCTGATCGACACGGTCGTGGGCGGCGACACGCTGCCCGAGCGGAAGCCCGATCCCGCGCCGCTCCGG
GAGGCCCTGCGCCGCCTGGGTGTCGCGCCCGGACGGGCCGTCATGGTCGGCGACATGCACCACGACATCGCGGCCGCCCG
GGCGGCCGGCACCGCCGCGATCCTGGCCCGCTACGGCTACGGGCGCCTCGAAGACGCCGAAGACGCCGACGCCGTCCTCG
ACGACATCGGCGGCCTGCGGGCGATGATCGGGGCGCTGCCCGCGGGCCGCGCCCCGGTCTCCTAG

Upstream 100 bases:

>100_bases
CGCCCTGGCCCGGGCGCACCGGACCCGCTAGGAACCGCCCGTCCCGGAGAGCGAGGCGTCGGCGTCCCGCGGCGGCCCGA
CTGCGACGCGGAGAACACCC

Downstream 100 bases:

>100_bases
CGGTTTCCCGCGAGGTCGGGGCGGGCGGGGGCGCCCGGCGCTCGGGTCTGCCGCTCGAGGAGGGCGCTGGCGCTGTCGGC
GAGGACGAGCCAGGCGCCGG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MPAPPPAAPSRFDAVLLDLDGTLVDSLADLRTALNETLAREGLPPVGAAAMRAMVGDGAVALLRRALRASGGDPGRAPAL
LPAFLAVYEPLAAAGTPLFPGAAAAVRDLRTAGYALAIVTNKPARATGLILDAVGLAPLIDTVVGGDTLPERKPDPAPLR
EALRRLGVAPGRAVMVGDMHHDIAAARAAGTAAILARYGYGRLEDAEDADAVLDDIGGLRAMIGALPAGRAPVS

Sequences:

>Translated_234_residues
MPAPPPAAPSRFDAVLLDLDGTLVDSLADLRTALNETLAREGLPPVGAAAMRAMVGDGAVALLRRALRASGGDPGRAPAL
LPAFLAVYEPLAAAGTPLFPGAAAAVRDLRTAGYALAIVTNKPARATGLILDAVGLAPLIDTVVGGDTLPERKPDPAPLR
EALRRLGVAPGRAVMVGDMHHDIAAARAAGTAAILARYGYGRLEDAEDADAVLDDIGGLRAMIGALPAGRAPVS
>Mature_233_residues
PAPPPAAPSRFDAVLLDLDGTLVDSLADLRTALNETLAREGLPPVGAAAMRAMVGDGAVALLRRALRASGGDPGRAPALL
PAFLAVYEPLAAAGTPLFPGAAAAVRDLRTAGYALAIVTNKPARATGLILDAVGLAPLIDTVVGGDTLPERKPDPAPLRE
ALRRLGVAPGRAVMVGDMHHDIAAARAAGTAAILARYGYGRLEDAEDADAVLDDIGGLRAMIGALPAGRAPVS

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=231, Percent_Identity=34.1991341991342, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23647; Mature: 23515

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPPPAAPSRFDAVLLDLDGTLVDSLADLRTALNETLAREGLPPVGAAAMRAMVGDGAV
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
ALLRRALRASGGDPGRAPALLPAFLAVYEPLAAAGTPLFPGAAAAVRDLRTAGYALAIVT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEEE
NKPARATGLILDAVGLAPLIDTVVGGDTLPERKPDPAPLREALRRLGVAPGRAVMVGDMH
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCHH
HDIAAARAAGTAAILARYGYGRLEDAEDADAVLDDIGGLRAMIGALPAGRAPVS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PAPPPAAPSRFDAVLLDLDGTLVDSLADLRTALNETLAREGLPPVGAAAMRAMVGDGAV
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
ALLRRALRASGGDPGRAPALLPAFLAVYEPLAAAGTPLFPGAAAAVRDLRTAGYALAIVT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEEE
NKPARATGLILDAVGLAPLIDTVVGGDTLPERKPDPAPLREALRRLGVAPGRAVMVGDMH
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCHH
HDIAAARAAGTAAILARYGYGRLEDAEDADAVLDDIGGLRAMIGALPAGRAPVS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]