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The map label for this gene is zraS [C]

Identifier: 170750821

GI number: 170750821

Start: 4712554

End: 4715130

Strand: Reverse

Name: zraS [C]

Synonym: Mrad2831_4432

Alternate gene names: 170750821

Gene position: 4715130-4712554 (Counterclockwise)

Preceding gene: 170750822

Following gene: 170750820

Centisome position: 77.58

GC content: 74.19

Gene sequence:

>2577_bases
GTGGACGAGACGGGGACCGAGGCGCTCCTGCGGCGCGCCCGCGCGCTGGAAGAGGAAGCCGCCGGCCTCCGGGCGCGGGC
GGCCGCCGCGCGGGAGGACGCCCGGCCGCTCCCGCAGCCCCCCGCGGATTCGGACGGGACCGGCCGGGCCCTCCGGGAGG
CCGAGGCGCGCCTGCTGCGGGCGCAGGAGGCGGGCGGGATCGGCCTGTTCACCGTCGGGGTCGACGACGGGCTCCTGCAC
CCGACCCCGCAATTCTGCCGGCTCTACGGCCTGCCGGAGCGCGACACCTACCCGGCCGAGCTGGTCGAGGCGCTGATCCT
GCCGGAGGACCAGGCGCTCATCTCGACGGCGGCGAGCCGGCGCCGCGGCGACGCCCCGCGGGACGTCGCCTACCGGATCC
GGCGGCCGGATACCGGGGAGATCCGCTGGATCGCCCGGCAGGGGGAGATCGAGCGCGACGCCGCGGGACGGCCGGTGCGG
TTCTCCGGAGTGGCGCGCGACATCACCGAGCAGCGGGAGGCCCGCGACGCCCTGCGCGCCGGCGAGGAGCGCTACCGAAC
CTTGTTCGAGGCCATCGACGACGGCTTCTGCATCATCGAGTTCTTCGACGGCCCGCACGGCCCGCTGAGCGACTACGTCC
ACGTCGAGGCCAATCCCGGCTACGAGCGCCACACCGGCATCGCCGGCATCGTCGGGCGGACGCTGCGCGACCTCGTGTCG
GCCGCGGACGCGGAGGCCTGGCTCGAACTCTACGGCGGCGTGCTGCGCTCCGGACTCCCGATCCGGTTCGAGCGCTTCTT
CGCCCAGGCCGACCGCTTCATCGACGTCTCGGCCGCCCGGATCGGGCCGGCGAGCCGGCGCCAGGTCTCGGTGCTGTTCC
GGGACATCACGGCGCGCCGGCAGGCGGAGGACGCCCTGCGCGCCAGCGAGGCGCTCGCCCGGACCAACATCGAGCGCGTG
CAGCTCGCCCTCGCGGCCGGCGCCATCATCGGCACGTGGCACTGGGACCTGCCGAGCGACCGGTTCACGGTCGACGAGGG
CTTCGCCCGCAGCTTCGGCCTCGACCCGGCGCTCGGCCGGGACGGCATCCCGCTCGCCCGGATCGTCGCGACCGTGCACC
CGGACGACCAGGCCGGGCTGGCGGCCGCCATCAACGCGGCCGTCGCCCGGGGCGGCGCCTACGCGCACCAGTACCGGGTG
CGCCGCGCCGACGGGCACTATTACTGGCTGGAGGCCAACGGCCGCGTCGACCACGCGCCCGACGGCACGCCGCTGAGCTT
CCCCGGGGTCCTGATCGACGTGGACGAGCGCCGCGCCGTCGAGGCCGAGCGGGACCGCGTCGCCGCGGCGCTGCGCAGCC
TCAACGAGACCCTGGAGCAGCGGGTCGCCGAGCGGACGGCCGAGCTGATGCGCGCCGAGGAGGCCCTGCGCCAGTCGCAG
AAGATGGAGGCGGTCGGCCAGCTCACCGGCGGGCTCGCCCACGACTTCAACAACATGCTGGCCGGGATCGTCGGCTCGCT
GGAGCTGATGCAGACCCGGATGCTGCAGGGGCGGGTCGGCGACCTCGACCGCTACATCGGCGCGGCGCAGGGCGCGGCCA
AGCGCGCCGCCGCCCTGACCCACCGCCTGCTGGCCTTCTCGCGCCGCCAGACCCTCGACCCGAAGCCGACGGACGCGAAC
CGCCTGGTCGAGGGCATGATGGAGCTCGTCCGCCGCACGGTCGGCCCGTCGGTGGCGATCGAGTCGGTCGGGGCCGGCGG
CCTGTGGCCGACGCTGGTCGACCCGAGCCAGCTCGAGAACGCGCTGCTCAACCTGTGCATCAACGCCCGGGACGCGATGC
CGGCGGGCGGGCGCATCGTCATCGAGACCGCCAACCGCTGGCTCGACCACCGGGCCGCCCAGGAACGCGAGCTGGAGCCG
GGGCAGTACGTGACGCTCTGCGTCTCGGACAACGGCACCGGCATGACCCCCGACGTGGTCGCCAAGGCCTTCGACCCGTT
CTTCACCACCAAGCCGATCGGCGAGGGCACCGGCCTCGGCCTGTCGATGATCTACGGCTTCGCCAAGCAGTCGGGCGGGC
AGGTCCGGATCTACTCGGAGGTCGGCCAGGGCACGATGGTCTGCCTCTACCTGCCCCGCCATCTCGGCGAGGCGGAGGCC
GAGGTGAGCCTGCCGGACCTCGCCCACGCGCCCCGCGCCGAGCAGGGCGAGACGGTCCTGGTGGTGGACGACGAGCCGAC
CGTGCGGATGCTGGTGACCGAGGTGCTGGAGGATCTCGGCTACGCGGCGATCGAGGCGGCGGACGGCGCCTCGGGGCTGA
AGGTGCTCCAGTCGGACGTGCGCATCGACATGCTCATCACCGATGTCGGGCTGCCCGGCGGCATGAACGGCCGCCAGATG
GCCGATGCCGGCCGCCAGCACCGCCCGGACCTGAAGGTCCTGTTCATCACCGGCTACGCCGAGAACGCCGCCCTCAACCA
CGGCCATCTCGGGCCCGGGATGCAGGTGATGACGAAGCCCTTCGCCCTGGAGGCGCTCGCCACCCGCATCCGCGGCATCA
TCGGCGGCGAGGGCTGA

Upstream 100 bases:

>100_bases
GCCCCGTGCCCGTATCACCCGCCCTCCCAGCCCCGGCGATCCGCCCCGACCGCCCCGCGCGGCCGGCGGGGGACGCGGTC
GCGACGCACGGACGCTGAGC

Downstream 100 bases:

>100_bases
GGTCCGGCGGCCCGGGCCGGCGGTGCCCCCGGGCACACGGCGTCGCAGGCCCGCGCGGAACGGGTTCGCCGGCCCGCGCG
TCATTGCCATACCGCGCCGG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 858; Mature: 858

Protein sequence:

>858_residues
MDETGTEALLRRARALEEEAAGLRARAAAAREDARPLPQPPADSDGTGRALREAEARLLRAQEAGGIGLFTVGVDDGLLH
PTPQFCRLYGLPERDTYPAELVEALILPEDQALISTAASRRRGDAPRDVAYRIRRPDTGEIRWIARQGEIERDAAGRPVR
FSGVARDITEQREARDALRAGEERYRTLFEAIDDGFCIIEFFDGPHGPLSDYVHVEANPGYERHTGIAGIVGRTLRDLVS
AADAEAWLELYGGVLRSGLPIRFERFFAQADRFIDVSAARIGPASRRQVSVLFRDITARRQAEDALRASEALARTNIERV
QLALAAGAIIGTWHWDLPSDRFTVDEGFARSFGLDPALGRDGIPLARIVATVHPDDQAGLAAAINAAVARGGAYAHQYRV
RRADGHYYWLEANGRVDHAPDGTPLSFPGVLIDVDERRAVEAERDRVAAALRSLNETLEQRVAERTAELMRAEEALRQSQ
KMEAVGQLTGGLAHDFNNMLAGIVGSLELMQTRMLQGRVGDLDRYIGAAQGAAKRAAALTHRLLAFSRRQTLDPKPTDAN
RLVEGMMELVRRTVGPSVAIESVGAGGLWPTLVDPSQLENALLNLCINARDAMPAGGRIVIETANRWLDHRAAQERELEP
GQYVTLCVSDNGTGMTPDVVAKAFDPFFTTKPIGEGTGLGLSMIYGFAKQSGGQVRIYSEVGQGTMVCLYLPRHLGEAEA
EVSLPDLAHAPRAEQGETVLVVDDEPTVRMLVTEVLEDLGYAAIEAADGASGLKVLQSDVRIDMLITDVGLPGGMNGRQM
ADAGRQHRPDLKVLFITGYAENAALNHGHLGPGMQVMTKPFALEALATRIRGIIGGEG

Sequences:

>Translated_858_residues
MDETGTEALLRRARALEEEAAGLRARAAAAREDARPLPQPPADSDGTGRALREAEARLLRAQEAGGIGLFTVGVDDGLLH
PTPQFCRLYGLPERDTYPAELVEALILPEDQALISTAASRRRGDAPRDVAYRIRRPDTGEIRWIARQGEIERDAAGRPVR
FSGVARDITEQREARDALRAGEERYRTLFEAIDDGFCIIEFFDGPHGPLSDYVHVEANPGYERHTGIAGIVGRTLRDLVS
AADAEAWLELYGGVLRSGLPIRFERFFAQADRFIDVSAARIGPASRRQVSVLFRDITARRQAEDALRASEALARTNIERV
QLALAAGAIIGTWHWDLPSDRFTVDEGFARSFGLDPALGRDGIPLARIVATVHPDDQAGLAAAINAAVARGGAYAHQYRV
RRADGHYYWLEANGRVDHAPDGTPLSFPGVLIDVDERRAVEAERDRVAAALRSLNETLEQRVAERTAELMRAEEALRQSQ
KMEAVGQLTGGLAHDFNNMLAGIVGSLELMQTRMLQGRVGDLDRYIGAAQGAAKRAAALTHRLLAFSRRQTLDPKPTDAN
RLVEGMMELVRRTVGPSVAIESVGAGGLWPTLVDPSQLENALLNLCINARDAMPAGGRIVIETANRWLDHRAAQERELEP
GQYVTLCVSDNGTGMTPDVVAKAFDPFFTTKPIGEGTGLGLSMIYGFAKQSGGQVRIYSEVGQGTMVCLYLPRHLGEAEA
EVSLPDLAHAPRAEQGETVLVVDDEPTVRMLVTEVLEDLGYAAIEAADGASGLKVLQSDVRIDMLITDVGLPGGMNGRQM
ADAGRQHRPDLKVLFITGYAENAALNHGHLGPGMQVMTKPFALEALATRIRGIIGGEG
>Mature_858_residues
MDETGTEALLRRARALEEEAAGLRARAAAAREDARPLPQPPADSDGTGRALREAEARLLRAQEAGGIGLFTVGVDDGLLH
PTPQFCRLYGLPERDTYPAELVEALILPEDQALISTAASRRRGDAPRDVAYRIRRPDTGEIRWIARQGEIERDAAGRPVR
FSGVARDITEQREARDALRAGEERYRTLFEAIDDGFCIIEFFDGPHGPLSDYVHVEANPGYERHTGIAGIVGRTLRDLVS
AADAEAWLELYGGVLRSGLPIRFERFFAQADRFIDVSAARIGPASRRQVSVLFRDITARRQAEDALRASEALARTNIERV
QLALAAGAIIGTWHWDLPSDRFTVDEGFARSFGLDPALGRDGIPLARIVATVHPDDQAGLAAAINAAVARGGAYAHQYRV
RRADGHYYWLEANGRVDHAPDGTPLSFPGVLIDVDERRAVEAERDRVAAALRSLNETLEQRVAERTAELMRAEEALRQSQ
KMEAVGQLTGGLAHDFNNMLAGIVGSLELMQTRMLQGRVGDLDRYIGAAQGAAKRAAALTHRLLAFSRRQTLDPKPTDAN
RLVEGMMELVRRTVGPSVAIESVGAGGLWPTLVDPSQLENALLNLCINARDAMPAGGRIVIETANRWLDHRAAQERELEP
GQYVTLCVSDNGTGMTPDVVAKAFDPFFTTKPIGEGTGLGLSMIYGFAKQSGGQVRIYSEVGQGTMVCLYLPRHLGEAEA
EVSLPDLAHAPRAEQGETVLVVDDEPTVRMLVTEVLEDLGYAAIEAADGASGLKVLQSDVRIDMLITDVGLPGGMNGRQM
ADAGRQHRPDLKVLFITGYAENAALNHGHLGPGMQVMTKPFALEALATRIRGIIGGEG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=28.1746031746032, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=29.535864978903, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=391, Percent_Identity=24.5524296675192, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=423, Percent_Identity=22.9314420803783, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=25.1851851851852, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 93099; Mature: 93099

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDETGTEALLRRARALEEEAAGLRARAAAAREDARPLPQPPADSDGTGRALREAEARLLR
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AQEAGGIGLFTVGVDDGLLHPTPQFCRLYGLPERDTYPAELVEALILPEDQALISTAASR
HHCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
RRGDAPRDVAYRIRRPDTGEIRWIARQGEIERDAAGRPVRFSGVARDITEQREARDALRA
HCCCCCHHHHHEECCCCCCCEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHC
GEERYRTLFEAIDDGFCIIEFFDGPHGPLSDYVHVEANPGYERHTGIAGIVGRTLRDLVS
CHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHH
AADAEAWLELYGGVLRSGLPIRFERFFAQADRFIDVSAARIGPASRRQVSVLFRDITARR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEHHHHCCCCCHHHHHHHHHHHHHHH
QAEDALRASEALARTNIERVQLALAAGAIIGTWHWDLPSDRFTVDEGFARSFGLDPALGR
HHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCCCEECCCCHHHHCCCCCCCCC
DGIPLARIVATVHPDDQAGLAAAINAAVARGGAYAHQYRVRRADGHYYWLEANGRVDHAP
CCCCHHHHHEEECCCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCCEEEEEECCCCCCCC
DGTPLSFPGVLIDVDERRAVEAERDRVAAALRSLNETLEQRVAERTAELMRAEEALRQSQ
CCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMEAVGQLTGGLAHDFNNMLAGIVGSLELMQTRMLQGRVGDLDRYIGAAQGAAKRAAALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
HRLLAFSRRQTLDPKPTDANRLVEGMMELVRRTVGPSVAIESVGAGGLWPTLVDPSQLEN
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCHHHHHH
ALLNLCINARDAMPAGGRIVIETANRWLDHRAAQERELEPGQYVTLCVSDNGTGMTPDVV
HHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHH
AKAFDPFFTTKPIGEGTGLGLSMIYGFAKQSGGQVRIYSEVGQGTMVCLYLPRHLGEAEA
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECHHCCCCCC
EVSLPDLAHAPRAEQGETVLVVDDEPTVRMLVTEVLEDLGYAAIEAADGASGLKVLQSDV
CCCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCC
RIDMLITDVGLPGGMNGRQMADAGRQHRPDLKVLFITGYAENAALNHGHLGPGMQVMTKP
EEEEEEEECCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCH
FALEALATRIRGIIGGEG
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDETGTEALLRRARALEEEAAGLRARAAAAREDARPLPQPPADSDGTGRALREAEARLLR
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AQEAGGIGLFTVGVDDGLLHPTPQFCRLYGLPERDTYPAELVEALILPEDQALISTAASR
HHCCCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
RRGDAPRDVAYRIRRPDTGEIRWIARQGEIERDAAGRPVRFSGVARDITEQREARDALRA
HCCCCCHHHHHEECCCCCCCEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHC
GEERYRTLFEAIDDGFCIIEFFDGPHGPLSDYVHVEANPGYERHTGIAGIVGRTLRDLVS
CHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHH
AADAEAWLELYGGVLRSGLPIRFERFFAQADRFIDVSAARIGPASRRQVSVLFRDITARR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEHHHHCCCCCHHHHHHHHHHHHHHH
QAEDALRASEALARTNIERVQLALAAGAIIGTWHWDLPSDRFTVDEGFARSFGLDPALGR
HHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCCCEECCCCHHHHCCCCCCCCC
DGIPLARIVATVHPDDQAGLAAAINAAVARGGAYAHQYRVRRADGHYYWLEANGRVDHAP
CCCCHHHHHEEECCCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCCEEEEEECCCCCCCC
DGTPLSFPGVLIDVDERRAVEAERDRVAAALRSLNETLEQRVAERTAELMRAEEALRQSQ
CCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMEAVGQLTGGLAHDFNNMLAGIVGSLELMQTRMLQGRVGDLDRYIGAAQGAAKRAAALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
HRLLAFSRRQTLDPKPTDANRLVEGMMELVRRTVGPSVAIESVGAGGLWPTLVDPSQLEN
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCHHHHHH
ALLNLCINARDAMPAGGRIVIETANRWLDHRAAQERELEPGQYVTLCVSDNGTGMTPDVV
HHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHH
AKAFDPFFTTKPIGEGTGLGLSMIYGFAKQSGGQVRIYSEVGQGTMVCLYLPRHLGEAEA
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECHHCCCCCC
EVSLPDLAHAPRAEQGETVLVVDDEPTVRMLVTEVLEDLGYAAIEAADGASGLKVLQSDV
CCCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCC
RIDMLITDVGLPGGMNGRQMADAGRQHRPDLKVLFITGYAENAALNHGHLGPGMQVMTKP
EEEEEEEECCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCH
FALEALATRIRGIIGGEG
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA