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The map label for this gene is yciR [C]

Identifier: 170750801

GI number: 170750801

Start: 4680332

End: 4682056

Strand: Reverse

Name: yciR [C]

Synonym: Mrad2831_4412

Alternate gene names: 170750801

Gene position: 4682056-4680332 (Counterclockwise)

Preceding gene: 170750802

Following gene: 170750800

Centisome position: 77.03

GC content: 73.68

Gene sequence:

>1725_bases
ATGCGCCCGGATCCCCTGCCCGCCCGCCCGCCGCTCCGGGACGCGGGGTTCCCGATCCCGCCCGGGCAGGGCGCGGCGCG
CGACCCCCTGGTTCCCTATCTCGACGCGGCCCGGCAGGGCCTCCTGATGATCGACCGGGCCGGGACGGTCGTGGCGGCGA
GCGCGCCGGCGCGGCGGCTCCTGGAGAGCCTGACGGTCGCGCCGAGGATCGGTGCCGCCGCGCTGCCGCTGCTGCGGGCC
CTGCGGGACGGGAGCGCCCCGGCGCGGCACGCGACCCTGCGGGCCCTGCGCGGCGCGCTGGCCCGGCGGCAGCCCGCCCT
GTTCGAGGTGCGGCGCCGGGCACACACGGTCCAGGTCGAGCTCCACCCTCTCGCGGAGGGCGGCTGGGTCGTCACCCTGG
AGGACGTCAGCACCCGGAAGGCCACCGAGGCCCGGGCCGACGCGATGGCGCGGCTCGACCCGCTCACCGGCCTGCCGAAC
CGCCTGCTCCTGCGCGAGCGCCTCGCCGCAGCGCTGGAGCGGCTCGCGCGCCCGGGCGAGGGCTTCGCCCTGCTGCTCAT
CGACCTCGACCGGTTCAAGCCGGTCAACGACACCCTCGGCCACCCGATCGGGGACGCGCTGCTGGCGACGGTCGCCGACC
GCCTGCGCTCGACGGTGCAGGCCACCGACACGGTGGCGCGGATCGGCGGCGACGAGTTCGTCATCCTGCAGGCCGGGATC
CGCGACGCGGCCGGCACGCAGGCGCTCGCCCGCCGCGTCGTCGACCTGATCGGCCGGACCTACATGGTGGAGGGCCATCT
CCTGACGATCGGCGCCAGCGTCGGCGTGGCGCTCGCCCCCGCGGACGGGACCGACGCCGACCGGCTCCTGAAGAACGCCG
ACCTCGCCCTCTACCGGGCCAAGCTCGACGGCCGCGGCACCTACCGGTTCTTCGAGCCGGAGATGGATGCCCGCATGCAG
GCGCGCCGGAAGCTCGAGCTCGACATGCGCCAGGCGCTGGCCCGGCGGGAATTCCAGCTGCACTACCAGCCGCAGATGCA
GCTCGCGAGCGGCACGCTGATCGGCTGCGAGGCCCTGATCCGGTGGCGCCATCCCGACCGCGGCCTGGTCTCGCCCCTCG
ACTTCATCCCGCTGGCCGAGGAGATCGGCCTCATCGTCCCGATCGGCGAGTGGGTCGTCCGGCAGGCCTGCCGCGACGCC
GTGACCTGGCCGGACCCCATGTCGGTGGCGGTCAACGTCTCGCCCGCCCAGTTCAAGAGCGACCGCCTCGTGGAGACGAT
CATCTCGGCCCTGGCGGGTTCGGGGCTGCCGGCGCGGCGGCTCGAGGTCGAGATCACCGAGGGCGTGCTGCTGCAGGAGA
ACGACCGGACGCTCCAGACCCTGCACCGGCTGCGGGAGCTCGGCGTTCGCGTCTCCATGGACGATTTCGGCACCGGCTAC
TCGTCGCTCAGCTACCTGCGCTCGTTCCCCTTCGACAAGATCAAGATCGACCGGTCCTTCGTGAAGGATCTGACCAGCAA
GCCCGACGGCGAGGCGATCATCCGGGCCATCGCGGGGCTGGGGAGGAGCCTCGGCATGACCACCGTCGCGGAGGGCGTCG
AGACGTCCGAACAGATGCAGCGCATCCGGTTCGAGGGCTGCACCGACGTGCAGGGCTACCTGATCAGCAAGCCCGTTCCC
GCCGAGGACCTGCGCCAGGTCTTCGCCGCCTTCCCGCAGGCCTGA

Upstream 100 bases:

>100_bases
CGTATTTCTCGGCGGTTTAAACACGGAATTAGCATCCTTCCGGCTATCCAGGCGGGGTTTTCCCGCCGCGCGCTGCCCGG
CACTCCCGCGAGGCCCTGGC

Downstream 100 bases:

>100_bases
CTCCCCGCCCCTTCCGGACGCAAAGCCATGAGCGACCTCTACCGCCTCGTCTACGCCAGCAAGAACCTGCTCCAGGGCCC
GGAGCCGGAGGCGATGGCCG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MRPDPLPARPPLRDAGFPIPPGQGAARDPLVPYLDAARQGLLMIDRAGTVVAASAPARRLLESLTVAPRIGAAALPLLRA
LRDGSAPARHATLRALRGALARRQPALFEVRRRAHTVQVELHPLAEGGWVVTLEDVSTRKATEARADAMARLDPLTGLPN
RLLLRERLAAALERLARPGEGFALLLIDLDRFKPVNDTLGHPIGDALLATVADRLRSTVQATDTVARIGGDEFVILQAGI
RDAAGTQALARRVVDLIGRTYMVEGHLLTIGASVGVALAPADGTDADRLLKNADLALYRAKLDGRGTYRFFEPEMDARMQ
ARRKLELDMRQALARREFQLHYQPQMQLASGTLIGCEALIRWRHPDRGLVSPLDFIPLAEEIGLIVPIGEWVVRQACRDA
VTWPDPMSVAVNVSPAQFKSDRLVETIISALAGSGLPARRLEVEITEGVLLQENDRTLQTLHRLRELGVRVSMDDFGTGY
SSLSYLRSFPFDKIKIDRSFVKDLTSKPDGEAIIRAIAGLGRSLGMTTVAEGVETSEQMQRIRFEGCTDVQGYLISKPVP
AEDLRQVFAAFPQA

Sequences:

>Translated_574_residues
MRPDPLPARPPLRDAGFPIPPGQGAARDPLVPYLDAARQGLLMIDRAGTVVAASAPARRLLESLTVAPRIGAAALPLLRA
LRDGSAPARHATLRALRGALARRQPALFEVRRRAHTVQVELHPLAEGGWVVTLEDVSTRKATEARADAMARLDPLTGLPN
RLLLRERLAAALERLARPGEGFALLLIDLDRFKPVNDTLGHPIGDALLATVADRLRSTVQATDTVARIGGDEFVILQAGI
RDAAGTQALARRVVDLIGRTYMVEGHLLTIGASVGVALAPADGTDADRLLKNADLALYRAKLDGRGTYRFFEPEMDARMQ
ARRKLELDMRQALARREFQLHYQPQMQLASGTLIGCEALIRWRHPDRGLVSPLDFIPLAEEIGLIVPIGEWVVRQACRDA
VTWPDPMSVAVNVSPAQFKSDRLVETIISALAGSGLPARRLEVEITEGVLLQENDRTLQTLHRLRELGVRVSMDDFGTGY
SSLSYLRSFPFDKIKIDRSFVKDLTSKPDGEAIIRAIAGLGRSLGMTTVAEGVETSEQMQRIRFEGCTDVQGYLISKPVP
AEDLRQVFAAFPQA
>Mature_574_residues
MRPDPLPARPPLRDAGFPIPPGQGAARDPLVPYLDAARQGLLMIDRAGTVVAASAPARRLLESLTVAPRIGAAALPLLRA
LRDGSAPARHATLRALRGALARRQPALFEVRRRAHTVQVELHPLAEGGWVVTLEDVSTRKATEARADAMARLDPLTGLPN
RLLLRERLAAALERLARPGEGFALLLIDLDRFKPVNDTLGHPIGDALLATVADRLRSTVQATDTVARIGGDEFVILQAGI
RDAAGTQALARRVVDLIGRTYMVEGHLLTIGASVGVALAPADGTDADRLLKNADLALYRAKLDGRGTYRFFEPEMDARMQ
ARRKLELDMRQALARREFQLHYQPQMQLASGTLIGCEALIRWRHPDRGLVSPLDFIPLAEEIGLIVPIGEWVVRQACRDA
VTWPDPMSVAVNVSPAQFKSDRLVETIISALAGSGLPARRLEVEITEGVLLQENDRTLQTLHRLRELGVRVSMDDFGTGY
SSLSYLRSFPFDKIKIDRSFVKDLTSKPDGEAIIRAIAGLGRSLGMTTVAEGVETSEQMQRIRFEGCTDVQGYLISKPVP
AEDLRQVFAAFPQA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=430, Percent_Identity=35.8139534883721, Blast_Score=293, Evalue=3e-80,
Organism=Escherichia coli, GI87081921, Length=438, Percent_Identity=34.2465753424658, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI226510982, Length=436, Percent_Identity=29.8165137614679, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=36.4, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI87081980, Length=255, Percent_Identity=37.2549019607843, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1790496, Length=255, Percent_Identity=34.5098039215686, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788502, Length=256, Percent_Identity=35.15625, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1787055, Length=239, Percent_Identity=35.1464435146443, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=35.0210970464135, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI87081743, Length=239, Percent_Identity=34.3096234309623, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788381, Length=552, Percent_Identity=25.3623188405797, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1788849, Length=238, Percent_Identity=33.1932773109244, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=210, Percent_Identity=29.5238095238095, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI87081977, Length=161, Percent_Identity=34.1614906832298, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1786584, Length=179, Percent_Identity=31.8435754189944, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=38.6904761904762, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=34.8101265822785, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081881, Length=185, Percent_Identity=32.4324324324324, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=30.4878048780488, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082007, Length=182, Percent_Identity=31.3186813186813, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788956, Length=150, Percent_Identity=31.3333333333333, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=84, Percent_Identity=38.0952380952381, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787802, Length=186, Percent_Identity=31.7204301075269, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787056, Length=157, Percent_Identity=33.1210191082803, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787410, Length=150, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 62717; Mature: 62717

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPDPLPARPPLRDAGFPIPPGQGAARDPLVPYLDAARQGLLMIDRAGTVVAASAPARRL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCEEECCCHHHHH
LESLTVAPRIGAAALPLLRALRDGSAPARHATLRALRGALARRQPALFEVRRRAHTVQVE
HHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEE
LHPLAEGGWVVTLEDVSTRKATEARADAMARLDPLTGLPNRLLLRERLAAALERLARPGE
EEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC
GFALLLIDLDRFKPVNDTLGHPIGDALLATVADRLRSTVQATDTVARIGGDEFVILQAGI
CEEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
RDAAGTQALARRVVDLIGRTYMVEGHLLTIGASVGVALAPADGTDADRLLKNADLALYRA
CCCCHHHHHHHHHHHHHCCEEEECCEEEEEECCCCEEEECCCCCCHHHHHHCCCCEEEEE
KLDGRGTYRFFEPEMDARMQARRKLELDMRQALARREFQLHYQPQMQLASGTLIGCEALI
EECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCEEEHHHHH
RWRHPDRGLVSPLDFIPLAEEIGLIVPIGEWVVRQACRDAVTWPDPMSVAVNVSPAQFKS
HCCCCCCCCCCCHHHCCCHHHCCEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHH
DRLVETIISALAGSGLPARRLEVEITEGVLLQENDRTLQTLHRLRELGVRVSMDDFGTGY
HHHHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCHHHHHHHHHHHCCCEEEEHHCCCCH
SSLSYLRSFPFDKIKIDRSFVKDLTSKPDGEAIIRAIAGLGRSLGMTTVAEGVETSEQMQ
HHHHHHHHCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHCCHHCCHHHHHHHCCHHHHHH
RIRFEGCTDVQGYLISKPVPAEDLRQVFAAFPQA
HHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRPDPLPARPPLRDAGFPIPPGQGAARDPLVPYLDAARQGLLMIDRAGTVVAASAPARRL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCEEECCCHHHHH
LESLTVAPRIGAAALPLLRALRDGSAPARHATLRALRGALARRQPALFEVRRRAHTVQVE
HHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEE
LHPLAEGGWVVTLEDVSTRKATEARADAMARLDPLTGLPNRLLLRERLAAALERLARPGE
EEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC
GFALLLIDLDRFKPVNDTLGHPIGDALLATVADRLRSTVQATDTVARIGGDEFVILQAGI
CEEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
RDAAGTQALARRVVDLIGRTYMVEGHLLTIGASVGVALAPADGTDADRLLKNADLALYRA
CCCCHHHHHHHHHHHHHCCEEEECCEEEEEECCCCEEEECCCCCCHHHHHHCCCCEEEEE
KLDGRGTYRFFEPEMDARMQARRKLELDMRQALARREFQLHYQPQMQLASGTLIGCEALI
EECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCEEEHHHHH
RWRHPDRGLVSPLDFIPLAEEIGLIVPIGEWVVRQACRDAVTWPDPMSVAVNVSPAQFKS
HCCCCCCCCCCCHHHCCCHHHCCEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHH
DRLVETIISALAGSGLPARRLEVEITEGVLLQENDRTLQTLHRLRELGVRVSMDDFGTGY
HHHHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCHHHHHHHHHHHCCCEEEEHHCCCCH
SSLSYLRSFPFDKIKIDRSFVKDLTSKPDGEAIIRAIAGLGRSLGMTTVAEGVETSEQMQ
HHHHHHHHCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHCCHHCCHHHHHHHCCHHHHHH
RIRFEGCTDVQGYLISKPVPAEDLRQVFAAFPQA
HHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]