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The map label for this gene is bedA [H]

Identifier: 170750738

GI number: 170750738

Start: 4609071

End: 4610621

Strand: Direct

Name: bedA [H]

Synonym: Mrad2831_4349

Alternate gene names: 170750738

Gene position: 4609071-4610621 (Clockwise)

Preceding gene: 170750737

Following gene: 170750739

Centisome position: 75.83

GC content: 75.31

Gene sequence:

>1551_bases
ATGAACCAGGACAAGCCCCGCGAGGTTCGCCTCGCCCTCGACGCGATCCCCCTCGGCGGCAAGGCCGAGGGCAAGGCCGG
CGACGACGCGGTGCTGTTCGTGCGCGACGCCGACGGCGTGCGCGCGTTCCAGGCGAAGTGCCCGCATCTCGGGGCGCCGC
TGGCCAAGGGCGAGATCTGCGGCGGCCGGCTCTACTGCCCCTGGCACAAGGCGGCCTTCGCGGTCGCCGACGGCGGCCTG
GAGGAGCCGCCGGCGCTGGAGGCGCTCACCCGCTATCCCGTCCGGATCGAGGGCGGCGAGGCCGTGGCGACGCTGACCCC
CGAGCCGGTCCCGGCGCGGCGGGCCGAGGCCCCGGTCGGGACGGTCCTGATCGTCGGCACCGGCGCGGCGGCCGTGGCCT
GCATCACCACCCTCCGGCGCGACGGGTTCGCGGGGACCATCACGATGGTCGGCCGCGAGGGCCACCCGCCCTACGACCGG
ACCAAGCTGTCCAAGCAGTTCCTGGCCAAGCCGACGCCCGCGGAGAAGACCCTGCTGGAGCCGGACTTCGCGGCCGCCCA
CCGCGTCGAGCGGGTCGTGGCCGAGGCGACGCGGGTCGATCCGGCCGGCCGCAGCGTCGCGCTGGCGGACGGGCGCACGC
TCACCGGCGACGCGCTGCTGATCGCCACCGGCAGCCGCGCCGTGGTGCCGGATCTCGAGGGAAAGGACCGCGACGGCGTG
ATGACCCTGCGCAGCCTCGACGACGCGGTGCGGCTCAGCGCCGCGGCGGAGCGGGCGACGCGCGTCGTGGTGATCGGCGC
GGGCTTCATCGGCCTGGAGGCGGCGGCCTTCCTGACCAAGCGCGGCCTGTCGGTGACGGTCCTGTCCCGGGAGGAGATCC
CCTTCGCCAAGCGCTTCGGCGAGGCCGTGGGCGCGGCGCTGAAGCGCTACCACGCCGGCAACGGCGTGACCTTCGTGACC
GGCACGGTCGCGCGGATCGCCGGAACCGGGTCGGTCGAGGCCGTCGAGACCGAGGACGGCGCGCGGCTCCCGGCCGACCT
CGTGCTGATCGGCGCCGGCGCCGCCCCGGAGACCGGGATCGTCGCCGGGGTCGAGCCGGACGAGGCCGGCGGTCTCCCGG
TCGGCGCCGACCTGAGGCTCGCCGACAACGTCTGGGTCGCGGGCGACATCGCGTCCTTCCCGGAGCGCGCCAGCGGCATC
ACGGCGCGGATCGAGCACTGGCGGCTGGCGCAGCAGCACGGCACGCACGTCGCCCGGGCGATGCTCGGCGCCACCGGCGT
CTTCGCGGGCGCGCCGTTCTTCTGGAGCAACCAGGGCGACAAGCGCCTGGATTACGGCGGCTACGCGCCGGATTTCGAGC
GGATCATCCTGCAGGGCGACCCGGCGGCGCTCGACTTCATCGCCTACTACGTCCGCGAGAACCGCGCGGTGGCGGCCTGC
AGCATCGGCCGCAACCCGGCCTTCACGGCGTTCCTCCACCTGCTGGGCGAGGGCCGCGTGCCCGGCCCCGACCAGATCGA
GGCCGGCGCCGATCTCGCCGCCCTGGTGTGA

Upstream 100 bases:

>100_bases
GCCGCCGCCCCTGCGACGGAAGGCGCGGAAACCCTTCGCGCCCTCGCGGTTTGGTGCGCGCGGGCCGGCTCGGCCCGGGC
CGGCACCGCGCGAGGCGAGG

Downstream 100 bases:

>100_bases
TGCCGCGGCGCGACAGCAGCGCGACATCAGCGCGGCCGGGCCGGTGGAACCAGGTCCGGCGGTCCCTCTTTCGGTAGACG
CCCGCCGTCTCGAGAGCCGG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MNQDKPREVRLALDAIPLGGKAEGKAGDDAVLFVRDADGVRAFQAKCPHLGAPLAKGEICGGRLYCPWHKAAFAVADGGL
EEPPALEALTRYPVRIEGGEAVATLTPEPVPARRAEAPVGTVLIVGTGAAAVACITTLRRDGFAGTITMVGREGHPPYDR
TKLSKQFLAKPTPAEKTLLEPDFAAAHRVERVVAEATRVDPAGRSVALADGRTLTGDALLIATGSRAVVPDLEGKDRDGV
MTLRSLDDAVRLSAAAERATRVVVIGAGFIGLEAAAFLTKRGLSVTVLSREEIPFAKRFGEAVGAALKRYHAGNGVTFVT
GTVARIAGTGSVEAVETEDGARLPADLVLIGAGAAPETGIVAGVEPDEAGGLPVGADLRLADNVWVAGDIASFPERASGI
TARIEHWRLAQQHGTHVARAMLGATGVFAGAPFFWSNQGDKRLDYGGYAPDFERIILQGDPAALDFIAYYVRENRAVAAC
SIGRNPAFTAFLHLLGEGRVPGPDQIEAGADLAALV

Sequences:

>Translated_516_residues
MNQDKPREVRLALDAIPLGGKAEGKAGDDAVLFVRDADGVRAFQAKCPHLGAPLAKGEICGGRLYCPWHKAAFAVADGGL
EEPPALEALTRYPVRIEGGEAVATLTPEPVPARRAEAPVGTVLIVGTGAAAVACITTLRRDGFAGTITMVGREGHPPYDR
TKLSKQFLAKPTPAEKTLLEPDFAAAHRVERVVAEATRVDPAGRSVALADGRTLTGDALLIATGSRAVVPDLEGKDRDGV
MTLRSLDDAVRLSAAAERATRVVVIGAGFIGLEAAAFLTKRGLSVTVLSREEIPFAKRFGEAVGAALKRYHAGNGVTFVT
GTVARIAGTGSVEAVETEDGARLPADLVLIGAGAAPETGIVAGVEPDEAGGLPVGADLRLADNVWVAGDIASFPERASGI
TARIEHWRLAQQHGTHVARAMLGATGVFAGAPFFWSNQGDKRLDYGGYAPDFERIILQGDPAALDFIAYYVRENRAVAAC
SIGRNPAFTAFLHLLGEGRVPGPDQIEAGADLAALV
>Mature_516_residues
MNQDKPREVRLALDAIPLGGKAEGKAGDDAVLFVRDADGVRAFQAKCPHLGAPLAKGEICGGRLYCPWHKAAFAVADGGL
EEPPALEALTRYPVRIEGGEAVATLTPEPVPARRAEAPVGTVLIVGTGAAAVACITTLRRDGFAGTITMVGREGHPPYDR
TKLSKQFLAKPTPAEKTLLEPDFAAAHRVERVVAEATRVDPAGRSVALADGRTLTGDALLIATGSRAVVPDLEGKDRDGV
MTLRSLDDAVRLSAAAERATRVVVIGAGFIGLEAAAFLTKRGLSVTVLSREEIPFAKRFGEAVGAALKRYHAGNGVTFVT
GTVARIAGTGSVEAVETEDGARLPADLVLIGAGAAPETGIVAGVEPDEAGGLPVGADLRLADNVWVAGDIASFPERASGI
TARIEHWRLAQQHGTHVARAMLGATGVFAGAPFFWSNQGDKRLDYGGYAPDFERIILQGDPAALDFIAYYVRENRAVAAC
SIGRNPAFTAFLHLLGEGRVPGPDQIEAGADLAALV

Specific function: Part of the electron transfer component of benzene 1,2- dioxygenase, transfers electrons from ferredoxin to NADH [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=518, Percent_Identity=33.976833976834, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI226437568, Length=518, Percent_Identity=33.976833976834, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI21389617, Length=510, Percent_Identity=33.921568627451, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI4757732, Length=259, Percent_Identity=27.4131274131274, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI22202629, Length=259, Percent_Identity=27.4131274131274, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1788892, Length=369, Percent_Identity=27.6422764227642, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789765, Length=317, Percent_Identity=27.4447949526814, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559934, Length=518, Percent_Identity=27.2200772200772, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24585130, Length=497, Percent_Identity=30.5835010060362, Blast_Score=241, Evalue=6e-64,
Organism=Drosophila melanogaster, GI24639257, Length=504, Percent_Identity=32.3412698412698, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI281359715, Length=504, Percent_Identity=32.3412698412698, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI281359713, Length=504, Percent_Identity=32.3412698412698, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24639250, Length=504, Percent_Identity=32.3412698412698, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI18543267, Length=504, Percent_Identity=32.3412698412698, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24639252, Length=504, Percent_Identity=32.3412698412698, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24581020, Length=357, Percent_Identity=26.0504201680672, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28573993, Length=357, Percent_Identity=26.0504201680672, Blast_Score=96, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.3 [H]

Molecular weight: Translated: 53814; Mature: 53814

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQDKPREVRLALDAIPLGGKAEGKAGDDAVLFVRDADGVRAFQAKCPHLGAPLAKGEIC
CCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCCCCC
GGRLYCPWHKAAFAVADGGLEEPPALEALTRYPVRIEGGEAVATLTPEPVPARRAEAPVG
CCEEECCHHHCEEEEECCCCCCCHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCCCC
TVLIVGTGAAAVACITTLRRDGFAGTITMVGREGHPPYDRTKLSKQFLAKPTPAEKTLLE
EEEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCC
PDFAAAHRVERVVAEATRVDPAGRSVALADGRTLTGDALLIATGSRAVVPDLEGKDRDGV
CCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCCEEEEEECCCEECCCCCCCCCCCE
MTLRSLDDAVRLSAAAERATRVVVIGAGFIGLEAAAFLTKRGLSVTVLSREEIPFAKRFG
EEHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
EAVGAALKRYHAGNGVTFVTGTVARIAGTGSVEAVETEDGARLPADLVLIGAGAAPETGI
HHHHHHHHHHCCCCCEEEEEEEEEHHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCE
VAGVEPDEAGGLPVGADLRLADNVWVAGDIASFPERASGITARIEHWRLAQQHGTHVARA
EECCCCCCCCCCCCCCCEEEECCEEEECCHHHCCHHHCCCCHHHHHHHHHHHHCHHHHHH
MLGATGVFAGAPFFWSNQGDKRLDYGGYAPDFERIILQGDPAALDFIAYYVRENRAVAAC
HHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEE
SIGRNPAFTAFLHLLGEGRVPGPDQIEAGADLAALV
ECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MNQDKPREVRLALDAIPLGGKAEGKAGDDAVLFVRDADGVRAFQAKCPHLGAPLAKGEIC
CCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCCCCC
GGRLYCPWHKAAFAVADGGLEEPPALEALTRYPVRIEGGEAVATLTPEPVPARRAEAPVG
CCEEECCHHHCEEEEECCCCCCCHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCCCC
TVLIVGTGAAAVACITTLRRDGFAGTITMVGREGHPPYDRTKLSKQFLAKPTPAEKTLLE
EEEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCC
PDFAAAHRVERVVAEATRVDPAGRSVALADGRTLTGDALLIATGSRAVVPDLEGKDRDGV
CCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCCEEEEEECCCEECCCCCCCCCCCE
MTLRSLDDAVRLSAAAERATRVVVIGAGFIGLEAAAFLTKRGLSVTVLSREEIPFAKRFG
EEHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
EAVGAALKRYHAGNGVTFVTGTVARIAGTGSVEAVETEDGARLPADLVLIGAGAAPETGI
HHHHHHHHHHCCCCCEEEEEEEEEHHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCE
VAGVEPDEAGGLPVGADLRLADNVWVAGDIASFPERASGITARIEHWRLAQQHGTHVARA
EECCCCCCCCCCCCCCCEEEECCEEEECCHHHCCHHHCCCCHHHHHHHHHHHHCHHHHHH
MLGATGVFAGAPFFWSNQGDKRLDYGGYAPDFERIILQGDPAALDFIAYYVRENRAVAAC
HHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEE
SIGRNPAFTAFLHLLGEGRVPGPDQIEAGADLAALV
ECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8344526 [H]