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The map label for this gene is atoS [C]

Identifier: 170750658

GI number: 170750658

Start: 4518714

End: 4520441

Strand: Reverse

Name: atoS [C]

Synonym: Mrad2831_4268

Alternate gene names: 170750658

Gene position: 4520441-4518714 (Counterclockwise)

Preceding gene: 170750659

Following gene: 170750657

Centisome position: 74.38

GC content: 74.02

Gene sequence:

>1728_bases
GTGATCGGACCTTCCGCGGGGCCGCTGCGCATCCTCCACCTGGAGGACAGCGACCTCGACGCCGAGCTGATCGAGGCCGA
GCTGGAGAGCCTCGGGCACCCGGTCGCGATCGAGCGGGTGATGACCCGCGACGCCTTCGCCCGCGCGGCGGTCGCCGGCC
GGCACGACCTCATCCTGGCGGACTACGTCCTGCCGACCTTCGACGGCGTGAGTGCGCTCGGCATCGCCCGGGCGCAGTGC
CCCGACACGCCGTTCATCTTCTGCTCGGGCACGCTCGGCGAGGATGTCGCGGTCGAGGCCCTGAAGAACGGCGCCACTGA
CTACGTCGTCAAGCAGCGCCTCGACCGCATGCCGCGCACGATCGTCCGCGCGCTCGCCGAGGCGCGGGCGCGCGCCGACA
AGCGCGAGGCCGAGGCCGCCCTGCAGGCGCTCAACGAGACGCTGGAGGTGCGCATCGCCGAGCGGACCCGGGAACTCGCC
GCGGCGAACGAGGCCCTCCAGGCCCAGATCGTCGAGCGGGAGCGGGCGGAGGACGCCCTGCGGCTCGCCCAGCGCCTGGA
CGCGGTCGGCCAGCTCACGAGCGGCGTCGCGCACGACTTCAACAACCTGCTGACGGTGATCGCCGGCAACATCGAGTTCC
TGGAGAAGGCCGTCTCCGACGCGCGCTCGAAGCGCCGCCTCGCCATGATGCGCGGGGCCGCCGAGCGCGGCGCCCGGCTC
ACCGCGCAGCTCCTCGCCTTCTCCCGCCGCCAGCGCCTGGAGCCGACGCCGGTCAGCCTCAACCAGACGGTCGCCTCGAT
GCGCGACCTGCTGCAGAGCTCGATCGGCGGCGCGGTCCGGATCGAGACGACCCTCCAGCCCGACCTGTGGCCCGCCCTGG
TCGACGCCACTCAGATCGAGCTGGTGATCCTGAACCTCGCCATCAACGCCCGCGACGCGATGGCGGTGGGCGGCCGGCTC
GCCATCGAGACCGCCAATGTCAGCGTCACCGGGGCGCCGACGCGGCCCGAGCAGCCGGCGCCCGGCGCCTACGTCATGGT
CGCGGTGAGCGACACCGGTACCGGGATGACGCCGGACGTGCTGGCGCGGGTGTTCGAGCCGTTCTTCACCACCAAGGAGG
TCGGCAAGGGGTCGGGTCTCGGGCTCGCCCAGGTCTACGGCTTCGTCAAGCAGTCCGGCGGCGGCATCCGCATCGACACG
GTCGCGGGCGAGGGCACCTCGATCAAGGTCTACCTGCCCCGGGCCGCGGAGCCCGAGGGCGCCGTGCCCCGCCTGCCGGT
CGCGGCCGAGGCCGCGCGGGCGCACCCGCCCGGAGGCGGCCCCCGGCTCCTGGTGGTCGACGACGACGCCGAGGTGCGCG
AGGTGACGACGACCCGCCTGATCGAGGCCGGCTACGCGGTGCGCGAGGCGGCCTCCGGCCTCCAGGCGCTGGCCGCCCTG
GAGGCGGATCCGGCCGTCGACCTCGTCGTGATGGACTTCGCCATGCCGGGCATGAACGGGGCCGAGACGGCCCTGGAGGT
CCGGAAGCGCTGGCCGGCGCTGCCGGTCCTGTTCGTCACCGGCTTCGCCGACACCAGCGCCCTGACCAAGGCCGGCGCCG
TCGGCACCGACGCGATCGTGCTGAAGCCGTTCCGCGTCGGGGAACTCGAGGGCAAGGTCGCCGCCGCCCTGGCGGCCCGC
CCACCGGCGCAGCTCCGGCTGATCTCGGGCCGCGACAGGAGCGCCTGA

Upstream 100 bases:

>100_bases
TCGCCTTCGAGGAGTTCTTCGCGGCGATCAAGGAGATCGGCGTCTTCTGGGCCCTCCTCAACGAGCCGCCGCCGTACCGG
GGAGGCTGGCCATCGAACGC

Downstream 100 bases:

>100_bases
GGCGTCCTGAGGGCGTCCTCCACACGGGTCGCGGCGTTCGACGGGCCCGACTTGATCGATGCAGTTGCACAGGCCCGCGC
GCTGGGGCACCGATGGCACT

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MIGPSAGPLRILHLEDSDLDAELIEAELESLGHPVAIERVMTRDAFARAAVAGRHDLILADYVLPTFDGVSALGIARAQC
PDTPFIFCSGTLGEDVAVEALKNGATDYVVKQRLDRMPRTIVRALAEARARADKREAEAALQALNETLEVRIAERTRELA
AANEALQAQIVERERAEDALRLAQRLDAVGQLTSGVAHDFNNLLTVIAGNIEFLEKAVSDARSKRRLAMMRGAAERGARL
TAQLLAFSRRQRLEPTPVSLNQTVASMRDLLQSSIGGAVRIETTLQPDLWPALVDATQIELVILNLAINARDAMAVGGRL
AIETANVSVTGAPTRPEQPAPGAYVMVAVSDTGTGMTPDVLARVFEPFFTTKEVGKGSGLGLAQVYGFVKQSGGGIRIDT
VAGEGTSIKVYLPRAAEPEGAVPRLPVAAEAARAHPPGGGPRLLVVDDDAEVREVTTTRLIEAGYAVREAASGLQALAAL
EADPAVDLVVMDFAMPGMNGAETALEVRKRWPALPVLFVTGFADTSALTKAGAVGTDAIVLKPFRVGELEGKVAAALAAR
PPAQLRLISGRDRSA

Sequences:

>Translated_575_residues
MIGPSAGPLRILHLEDSDLDAELIEAELESLGHPVAIERVMTRDAFARAAVAGRHDLILADYVLPTFDGVSALGIARAQC
PDTPFIFCSGTLGEDVAVEALKNGATDYVVKQRLDRMPRTIVRALAEARARADKREAEAALQALNETLEVRIAERTRELA
AANEALQAQIVERERAEDALRLAQRLDAVGQLTSGVAHDFNNLLTVIAGNIEFLEKAVSDARSKRRLAMMRGAAERGARL
TAQLLAFSRRQRLEPTPVSLNQTVASMRDLLQSSIGGAVRIETTLQPDLWPALVDATQIELVILNLAINARDAMAVGGRL
AIETANVSVTGAPTRPEQPAPGAYVMVAVSDTGTGMTPDVLARVFEPFFTTKEVGKGSGLGLAQVYGFVKQSGGGIRIDT
VAGEGTSIKVYLPRAAEPEGAVPRLPVAAEAARAHPPGGGPRLLVVDDDAEVREVTTTRLIEAGYAVREAASGLQALAAL
EADPAVDLVVMDFAMPGMNGAETALEVRKRWPALPVLFVTGFADTSALTKAGAVGTDAIVLKPFRVGELEGKVAAALAAR
PPAQLRLISGRDRSA
>Mature_575_residues
MIGPSAGPLRILHLEDSDLDAELIEAELESLGHPVAIERVMTRDAFARAAVAGRHDLILADYVLPTFDGVSALGIARAQC
PDTPFIFCSGTLGEDVAVEALKNGATDYVVKQRLDRMPRTIVRALAEARARADKREAEAALQALNETLEVRIAERTRELA
AANEALQAQIVERERAEDALRLAQRLDAVGQLTSGVAHDFNNLLTVIAGNIEFLEKAVSDARSKRRLAMMRGAAERGARL
TAQLLAFSRRQRLEPTPVSLNQTVASMRDLLQSSIGGAVRIETTLQPDLWPALVDATQIELVILNLAINARDAMAVGGRL
AIETANVSVTGAPTRPEQPAPGAYVMVAVSDTGTGMTPDVLARVFEPFFTTKEVGKGSGLGLAQVYGFVKQSGGGIRIDT
VAGEGTSIKVYLPRAAEPEGAVPRLPVAAEAARAHPPGGGPRLLVVDDDAEVREVTTTRLIEAGYAVREAASGLQALAAL
EADPAVDLVVMDFAMPGMNGAETALEVRKRWPALPVLFVTGFADTSALTKAGAVGTDAIVLKPFRVGELEGKVAAALAAR
PPAQLRLISGRDRSA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=31.3253012048193, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=30.0411522633745, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788713, Length=217, Percent_Identity=25.8064516129032, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI48994928, Length=399, Percent_Identity=24.0601503759398, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=35.3448275862069, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081816, Length=183, Percent_Identity=26.775956284153, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60899; Mature: 60899

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGPSAGPLRILHLEDSDLDAELIEAELESLGHPVAIERVMTRDAFARAAVAGRHDLILA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
DYVLPTFDGVSALGIARAQCPDTPFIFCSGTLGEDVAVEALKNGATDYVVKQRLDRMPRT
HHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
IVRALAEARARADKREAEAALQALNETLEVRIAERTRELAAANEALQAQIVERERAEDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAQRLDAVGQLTSGVAHDFNNLLTVIAGNIEFLEKAVSDARSKRRLAMMRGAAERGARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAQLLAFSRRQRLEPTPVSLNQTVASMRDLLQSSIGGAVRIETTLQPDLWPALVDATQIE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCEEE
LVILNLAINARDAMAVGGRLAIETANVSVTGAPTRPEQPAPGAYVMVAVSDTGTGMTPDV
EEEEEEEECCCHHHHCCCEEEEEECCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHH
LARVFEPFFTTKEVGKGSGLGLAQVYGFVKQSGGGIRIDTVAGEGTSIKVYLPRAAEPEG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCC
AVPRLPVAAEAARAHPPGGGPRLLVVDDDAEVREVTTTRLIEAGYAVREAASGLQALAAL
CCCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EADPAVDLVVMDFAMPGMNGAETALEVRKRWPALPVLFVTGFADTSALTKAGAVGTDAIV
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCCEEE
LKPFRVGELEGKVAAALAARPPAQLRLISGRDRSA
ECCEECCCCCCHHHHHHHCCCCHHEEEECCCCCCC
>Mature Secondary Structure
MIGPSAGPLRILHLEDSDLDAELIEAELESLGHPVAIERVMTRDAFARAAVAGRHDLILA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
DYVLPTFDGVSALGIARAQCPDTPFIFCSGTLGEDVAVEALKNGATDYVVKQRLDRMPRT
HHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
IVRALAEARARADKREAEAALQALNETLEVRIAERTRELAAANEALQAQIVERERAEDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAQRLDAVGQLTSGVAHDFNNLLTVIAGNIEFLEKAVSDARSKRRLAMMRGAAERGARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAQLLAFSRRQRLEPTPVSLNQTVASMRDLLQSSIGGAVRIETTLQPDLWPALVDATQIE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCEEE
LVILNLAINARDAMAVGGRLAIETANVSVTGAPTRPEQPAPGAYVMVAVSDTGTGMTPDV
EEEEEEEECCCHHHHCCCEEEEEECCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHH
LARVFEPFFTTKEVGKGSGLGLAQVYGFVKQSGGGIRIDTVAGEGTSIKVYLPRAAEPEG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCC
AVPRLPVAAEAARAHPPGGGPRLLVVDDDAEVREVTTTRLIEAGYAVREAASGLQALAAL
CCCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EADPAVDLVVMDFAMPGMNGAETALEVRKRWPALPVLFVTGFADTSALTKAGAVGTDAIV
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCCEEE
LKPFRVGELEGKVAAALAARPPAQLRLISGRDRSA
ECCEECCCCCCHHHHHHHCCCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA