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The map label for this gene is yagR [H]

Identifier: 170750653

GI number: 170750653

Start: 4508928

End: 4511147

Strand: Direct

Name: yagR [H]

Synonym: Mrad2831_4263

Alternate gene names: 170750653

Gene position: 4508928-4511147 (Clockwise)

Preceding gene: 170750652

Following gene: 170750662

Centisome position: 74.19

GC content: 72.34

Gene sequence:

>2220_bases
ATGAAGTTCGACACCGCCGCGGGCCCGAACCCGATCGACCGCCTCAAGGTCGTCGGCCGGCCCACCGACCGCATCGACGG
CAAGTACAAGACCACCGGCACCGCGCCCTACGCGTACGAGCGCCACGACGCGGCCCCCGACGCCGCCTACGGCTACGTGC
TGGGCTCCGCCATCGCCAAGGGCCGGGTGCGCAGCATCGACACGGCCTCGGCCCGGCAGGCGCCCGGCGTCGTCGCCGTC
GTCACCACCCTCGACACGCCGCGGATCGAGCGCGGCGTGATGAACGTCGCCTACCTGTTCGGCGGCGACGTGATCCAGCA
CTACCACCAGGCGATCGCCGTGGTGGTGGCCGAGACCTTCGAGCAGGCCCGCGCGGCCGCCTTCCTGGTGACGGTCGATT
ACGCCCCCGAGGCCGGTGCGTTCGACCTCGCCGCCGCGGCGAAGACCGCCGAGCCGGTCCCGGCCGACAGCGGCGAGGGC
AGCGGCGGCGACGGCGAGGAGCGGGTCGGCGATTTCGAGGGCGCCTTCGCGCAGGCGCCCGTGACGCTCGACGCGACCTA
CACGACGTCCGACGAGAGCCACGCCATGATGGAGCCGCACGCCACGACGGCGGCCTGGGACGGCGACCGGGTCACGCTCT
GGACCGCCAACCAGATGATCGGCTGGGGCCACGGCAGCCTCGCCAAGATGCTCGGCCTGCCGAAGGACAAGGTCCGGCTC
GACGCGCCCTACGTCGGCGGCGGCTTCGGCGGCAAGCTGTTCGTGCGCGCCGACGCGGTGCTGGCGGCGCTCGCCGCGAA
GGCGGCGGGGCGGCCCGTGAAGGTGGCGCTGACGCGCCCGCTCATCGCCAACAACACCACGCACCGGCCGGCCACGATCC
AGCGGGTGCGGATCGGCGCGACCCAGGACGGCACCATCACGGCGATCGCGCACGAGAGCACGTCGGGCAACCTGCCGGAC
GGCGACCCCGAGACGGCGGTGAACCAGACCAAGTACCTCTACGCGGGGGCGAACCGCCTGACCGCCATGAAGCTCGCCCG
TCTCGACCTGCCCGAGGGCAACGCCATGCGGGCGCCGGGCGAGGCCCCGGGGCTGGCGGTGCTCGAGGTCGCCATGGACG
AGATGGCGGAGAAGCTCGGCCTCGACCCGGTGGAGTTCCGCATCCGCAACGACACGCAGGTCGTCCCGACCCAGCCGGAC
CTGCGCTTCTCACACCGCGACCTCGTCGGCTGCCTCAAGCTCGGCGCCGAGCGGTTCGGCTGGGCCAGGCGCAACCCGAA
GCCCGGCCAGGTCCGGGAGGGGCAGTGGCTCGTCGGGCACGGCATGGCGGCGGCCTTCCGCGACAACATGGTGCTGAAGT
CGGGCGCCCGGGTGCGGCTCTCGGCCGACGGCACGGTCACGGTCGAGACCGACATGACCGATATCGGCACCGGCAGCTAC
ACGATCATCGCGCAGACCGCCGCCGAGATGATGGGCGTGCCCCTCGACCGGGTCGTGGCGCGGCTCGGCGACTCGGACTT
CCCGGTCTCGTCGGGCTCGGGCGGCCAGTTCGGCGCCAACTCGTCGACCGCGGGCGTCTACGCGGCCTGCGTGAAACTGC
GGGAGGCGGTCGCGCAGAAGCTCGGCTTCAACGCCACCGACGCGGTGTTCGAGGACGGCGAGGTCCGCGCCGGCAACCGC
GCCATCCCGCTGGCCCAGGCCGCCGCCGACGGCGAACTGGTGGCCGAGGACGCGATCGAGTTCGGCAAGTTCTCGAAGAC
GCAGCAGGTCTCGACCTTCGGGGCCCACTTCGTCGAGGTCGCGGTGGATGCCGACACCGCCGAGGTCCGGGTGCGGCGGA
TGCTGGCGGTCTGCGCGGCGGGGCGCATCCTCAACCCCAAATCCGCCCGCAGCCAGGTGATCGGCGGGATGGTCATGGGC
ACCGGCGCGGCCCTGATGGAGGAGCTCGCCGTCGACACCAAGCGCGGCTTCTTCGCCAACCACGACCTCGCCGGCTACGA
GGTGCCGGTCCACGCCGACATCCCGCACCAGGAGGTGATCTTCCTCGACGAGGTCGACCCGATGTCCTCACCCATGAAGG
CCAAGGGCGTGGGTGAGCTCGGCATCTCGGGGGTCGGCGCCGCGGTCGCGAACGCGATCTACAACGCCACCGGCATCCGC
GTGCGCGACTACCCGATCACCCTCGACAAGCTCCTCGACCGCATGCCGGACGCGGCCTGA

Upstream 100 bases:

>100_bases
GGTCTTCGCCGACGCCGCGCCCACCCACGAGAACGCCTACAAGCTGAAGCTCGCCGAGCGGACCCTCGGCGCCGCGCTCA
ACCAAGCGAGGGCCTGAGCC

Downstream 100 bases:

>100_bases
CCGGGGCGCGGGGACGTCCTGCCGGGCGTCCCCTACGGGTCCACGACGTGGAAGCTGGCCCGGGCCAGCATCACGAGGCG
ACCGTCCTCGTCGTAGGCGC

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 739; Mature: 739

Protein sequence:

>739_residues
MKFDTAAGPNPIDRLKVVGRPTDRIDGKYKTTGTAPYAYERHDAAPDAAYGYVLGSAIAKGRVRSIDTASARQAPGVVAV
VTTLDTPRIERGVMNVAYLFGGDVIQHYHQAIAVVVAETFEQARAAAFLVTVDYAPEAGAFDLAAAAKTAEPVPADSGEG
SGGDGEERVGDFEGAFAQAPVTLDATYTTSDESHAMMEPHATTAAWDGDRVTLWTANQMIGWGHGSLAKMLGLPKDKVRL
DAPYVGGGFGGKLFVRADAVLAALAAKAAGRPVKVALTRPLIANNTTHRPATIQRVRIGATQDGTITAIAHESTSGNLPD
GDPETAVNQTKYLYAGANRLTAMKLARLDLPEGNAMRAPGEAPGLAVLEVAMDEMAEKLGLDPVEFRIRNDTQVVPTQPD
LRFSHRDLVGCLKLGAERFGWARRNPKPGQVREGQWLVGHGMAAAFRDNMVLKSGARVRLSADGTVTVETDMTDIGTGSY
TIIAQTAAEMMGVPLDRVVARLGDSDFPVSSGSGGQFGANSSTAGVYAACVKLREAVAQKLGFNATDAVFEDGEVRAGNR
AIPLAQAAADGELVAEDAIEFGKFSKTQQVSTFGAHFVEVAVDADTAEVRVRRMLAVCAAGRILNPKSARSQVIGGMVMG
TGAALMEELAVDTKRGFFANHDLAGYEVPVHADIPHQEVIFLDEVDPMSSPMKAKGVGELGISGVGAAVANAIYNATGIR
VRDYPITLDKLLDRMPDAA

Sequences:

>Translated_739_residues
MKFDTAAGPNPIDRLKVVGRPTDRIDGKYKTTGTAPYAYERHDAAPDAAYGYVLGSAIAKGRVRSIDTASARQAPGVVAV
VTTLDTPRIERGVMNVAYLFGGDVIQHYHQAIAVVVAETFEQARAAAFLVTVDYAPEAGAFDLAAAAKTAEPVPADSGEG
SGGDGEERVGDFEGAFAQAPVTLDATYTTSDESHAMMEPHATTAAWDGDRVTLWTANQMIGWGHGSLAKMLGLPKDKVRL
DAPYVGGGFGGKLFVRADAVLAALAAKAAGRPVKVALTRPLIANNTTHRPATIQRVRIGATQDGTITAIAHESTSGNLPD
GDPETAVNQTKYLYAGANRLTAMKLARLDLPEGNAMRAPGEAPGLAVLEVAMDEMAEKLGLDPVEFRIRNDTQVVPTQPD
LRFSHRDLVGCLKLGAERFGWARRNPKPGQVREGQWLVGHGMAAAFRDNMVLKSGARVRLSADGTVTVETDMTDIGTGSY
TIIAQTAAEMMGVPLDRVVARLGDSDFPVSSGSGGQFGANSSTAGVYAACVKLREAVAQKLGFNATDAVFEDGEVRAGNR
AIPLAQAAADGELVAEDAIEFGKFSKTQQVSTFGAHFVEVAVDADTAEVRVRRMLAVCAAGRILNPKSARSQVIGGMVMG
TGAALMEELAVDTKRGFFANHDLAGYEVPVHADIPHQEVIFLDEVDPMSSPMKAKGVGELGISGVGAAVANAIYNATGIR
VRDYPITLDKLLDRMPDAA
>Mature_739_residues
MKFDTAAGPNPIDRLKVVGRPTDRIDGKYKTTGTAPYAYERHDAAPDAAYGYVLGSAIAKGRVRSIDTASARQAPGVVAV
VTTLDTPRIERGVMNVAYLFGGDVIQHYHQAIAVVVAETFEQARAAAFLVTVDYAPEAGAFDLAAAAKTAEPVPADSGEG
SGGDGEERVGDFEGAFAQAPVTLDATYTTSDESHAMMEPHATTAAWDGDRVTLWTANQMIGWGHGSLAKMLGLPKDKVRL
DAPYVGGGFGGKLFVRADAVLAALAAKAAGRPVKVALTRPLIANNTTHRPATIQRVRIGATQDGTITAIAHESTSGNLPD
GDPETAVNQTKYLYAGANRLTAMKLARLDLPEGNAMRAPGEAPGLAVLEVAMDEMAEKLGLDPVEFRIRNDTQVVPTQPD
LRFSHRDLVGCLKLGAERFGWARRNPKPGQVREGQWLVGHGMAAAFRDNMVLKSGARVRLSADGTVTVETDMTDIGTGSY
TIIAQTAAEMMGVPLDRVVARLGDSDFPVSSGSGGQFGANSSTAGVYAACVKLREAVAQKLGFNATDAVFEDGEVRAGNR
AIPLAQAAADGELVAEDAIEFGKFSKTQQVSTFGAHFVEVAVDADTAEVRVRRMLAVCAAGRILNPKSARSQVIGGMVMG
TGAALMEELAVDTKRGFFANHDLAGYEVPVHADIPHQEVIFLDEVDPMSSPMKAKGVGELGISGVGAAVANAIYNATGIR
VRDYPITLDKLLDRMPDAA

Specific function: Unknown

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=712, Percent_Identity=24.7191011235955, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI71773480, Length=728, Percent_Identity=23.7637362637363, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI1786478, Length=737, Percent_Identity=66.4857530529172, Blast_Score=976, Evalue=0.0,
Organism=Escherichia coli, GI1789230, Length=756, Percent_Identity=29.7619047619048, Blast_Score=249, Evalue=6e-67,
Organism=Escherichia coli, GI1789246, Length=806, Percent_Identity=26.4267990074442, Blast_Score=204, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17540638, Length=705, Percent_Identity=25.531914893617, Blast_Score=152, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI32566215, Length=551, Percent_Identity=22.1415607985481, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24647199, Length=715, Percent_Identity=24.1958041958042, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24647195, Length=732, Percent_Identity=25.2732240437158, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24647197, Length=687, Percent_Identity=25.9097525473071, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24647193, Length=729, Percent_Identity=24.4170096021948, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17737937, Length=708, Percent_Identity=25, Blast_Score=113, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 77857; Mature: 77857

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDTAAGPNPIDRLKVVGRPTDRIDGKYKTTGTAPYAYERHDAAPDAAYGYVLGSAIAK
CCCCCCCCCCHHHHEEECCCCCHHCCCCEEECCCCCCEECCCCCCCCHHHHHHHHHHHHC
GRVRSIDTASARQAPGVVAVVTTLDTPRIERGVMNVAYLFGGDVIQHYHQAIAVVVAETF
CCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EQARAAAFLVTVDYAPEAGAFDLAAAAKTAEPVPADSGEGSGGDGEERVGDFEGAFAQAP
HHHCCEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEECC
VTLDATYTTSDESHAMMEPHATTAAWDGDRVTLWTANQMIGWGHGSLAKMLGLPKDKVRL
EEEEEEEECCCCCCCEECCCCCEEECCCCEEEEEECCCEEECCCCHHHHHHCCCHHHEEE
DAPYVGGGFGGKLFVRADAVLAALAAKAAGRPVKVALTRPLIANNTTHRPATIQRVRIGA
CCCEECCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCEEEEEEECC
TQDGTITAIAHESTSGNLPDGDPETAVNQTKYLYAGANRLTAMKLARLDLPEGNAMRAPG
CCCCEEEEEEECCCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCC
EAPGLAVLEVAMDEMAEKLGLDPVEFRIRNDTQVVPTQPDLRFSHRDLVGCLKLGAERFG
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHC
WARRNPKPGQVREGQWLVGHGMAAAFRDNMVLKSGARVRLSADGTVTVETDMTDIGTGSY
CCCCCCCCCCCCCCCEEEECCCHHHHHCCEEEECCCEEEEECCCEEEEEECCCCCCCCCE
TIIAQTAAEMMGVPLDRVVARLGDSDFPVSSGSGGQFGANSSTAGVYAACVKLREAVAQK
EEEEEHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGFNATDAVFEDGEVRAGNRAIPLAQAAADGELVAEDAIEFGKFSKTQQVSTFGAHFVEV
HCCCCCHHHCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCEEEEE
AVDADTAEVRVRRMLAVCAAGRILNPKSARSQVIGGMVMGTGAALMEELAVDTKRGFFAN
EECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHCCCEEEC
HDLAGYEVPVHADIPHQEVIFLDEVDPMSSPMKAKGVGELGISGVGAAVANAIYNATGIR
CCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCE
VRDYPITLDKLLDRMPDAA
EEECCCCHHHHHHHCCCCC
>Mature Secondary Structure
MKFDTAAGPNPIDRLKVVGRPTDRIDGKYKTTGTAPYAYERHDAAPDAAYGYVLGSAIAK
CCCCCCCCCCHHHHEEECCCCCHHCCCCEEECCCCCCEECCCCCCCCHHHHHHHHHHHHC
GRVRSIDTASARQAPGVVAVVTTLDTPRIERGVMNVAYLFGGDVIQHYHQAIAVVVAETF
CCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EQARAAAFLVTVDYAPEAGAFDLAAAAKTAEPVPADSGEGSGGDGEERVGDFEGAFAQAP
HHHCCEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEECC
VTLDATYTTSDESHAMMEPHATTAAWDGDRVTLWTANQMIGWGHGSLAKMLGLPKDKVRL
EEEEEEEECCCCCCCEECCCCCEEECCCCEEEEEECCCEEECCCCHHHHHHCCCHHHEEE
DAPYVGGGFGGKLFVRADAVLAALAAKAAGRPVKVALTRPLIANNTTHRPATIQRVRIGA
CCCEECCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCEEEEEEECC
TQDGTITAIAHESTSGNLPDGDPETAVNQTKYLYAGANRLTAMKLARLDLPEGNAMRAPG
CCCCEEEEEEECCCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCC
EAPGLAVLEVAMDEMAEKLGLDPVEFRIRNDTQVVPTQPDLRFSHRDLVGCLKLGAERFG
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHC
WARRNPKPGQVREGQWLVGHGMAAAFRDNMVLKSGARVRLSADGTVTVETDMTDIGTGSY
CCCCCCCCCCCCCCCEEEECCCHHHHHCCEEEECCCEEEEECCCEEEEEECCCCCCCCCE
TIIAQTAAEMMGVPLDRVVARLGDSDFPVSSGSGGQFGANSSTAGVYAACVKLREAVAQK
EEEEEHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGFNATDAVFEDGEVRAGNRAIPLAQAAADGELVAEDAIEFGKFSKTQQVSTFGAHFVEV
HCCCCCHHHCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCEEEEE
AVDADTAEVRVRRMLAVCAAGRILNPKSARSQVIGGMVMGTGAALMEELAVDTKRGFFAN
EECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHCCCEEEC
HDLAGYEVPVHADIPHQEVIFLDEVDPMSSPMKAKGVGELGISGVGAAVANAIYNATGIR
CCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCE
VRDYPITLDKLLDRMPDAA
EEECCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]