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The map label for this gene is moxX [H]

Identifier: 170750587

GI number: 170750587

Start: 4445787

End: 4446479

Strand: Reverse

Name: moxX [H]

Synonym: Mrad2831_4197

Alternate gene names: 170750587

Gene position: 4446479-4445787 (Counterclockwise)

Preceding gene: 170750588

Following gene: 170750585

Centisome position: 73.16

GC content: 74.17

Gene sequence:

>693_bases
GTGAGCGCCGCCCGGGCCTCGGCCGACCGCCCGGCGGGGCGGGACGGTCCGCGCGGTCTCGACGCGGTGCTGATCGTCGA
CGACCACCCGGTCGTGCGGCGCGGCTTCCGCCACCTCGCGGAGGATGCCGGCGTCCGGGCGGTCCACGAGGCCGCGGACG
TGGTGTCCGGCTACCGCACCTTCCACCGCCACCGGCCCGGGCTGGTGGTGACCGACCTCGGCTTCCGCGACCAGGGCCTG
TCGGGCCTGTCGCTGATCCGCCGGGTGCGGGCCCTGGAGCCGGCGACGCGGATCCTCGCCTTCAGCATGCACGACGACCC
GGTGATCGTCGCCCGCGCCATCGAGGGCGGGGCGCACGGCTTCGTCCTGAAGGACACGGCGGTGACGCGCTTTCACGAGG
CGCTGGCGACCGTCTCGGCCGGCCGCAGCTACCTGCCGCACGAGGTCGCGACCAAGATCGCCATGCTGAATGCCGGGCTC
CTGGAATCGCCCCTCGCGCGCCTGACCGCGCGGGAGGTTCAGGTCCTGTCGCTGCTGGGGGCGGGCAAGTCCAACGAGGC
GATCGCCGACAGCCTGTCGATGAGCCAGCGCAGCGTGTCGGCCGTCGTCTCGGGCATGAAGCAGAAGCTCGGCGCCGGCA
GCCTCGCCGACCTCCTGCGTATCGCCCTGTCGCGGGACGGGCGCCCGGTGTGA

Upstream 100 bases:

>100_bases
AGATGTGCCAGCACTACTACAACGCCCGGATGCAGGGGGCCGACCACGCGGCCGCGCTGGCCCGCCTCGCCGCCCCGCAC
CCGGCCCGCGAGGGGACGCC

Downstream 100 bases:

>100_bases
GGACGGCCGCCGTCAGCGCCGCAAACAGCGGGCCGGGGCTACCGCGGCACGACCAGGCCGGGAATGATCGATCCCCGCGG
CCCGAACGTCGCCTCGGCCT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSAARASADRPAGRDGPRGLDAVLIVDDHPVVRRGFRHLAEDAGVRAVHEAADVVSGYRTFHRHRPGLVVTDLGFRDQGL
SGLSLIRRVRALEPATRILAFSMHDDPVIVARAIEGGAHGFVLKDTAVTRFHEALATVSAGRSYLPHEVATKIAMLNAGL
LESPLARLTAREVQVLSLLGAGKSNEAIADSLSMSQRSVSAVVSGMKQKLGAGSLADLLRIALSRDGRPV

Sequences:

>Translated_230_residues
MSAARASADRPAGRDGPRGLDAVLIVDDHPVVRRGFRHLAEDAGVRAVHEAADVVSGYRTFHRHRPGLVVTDLGFRDQGL
SGLSLIRRVRALEPATRILAFSMHDDPVIVARAIEGGAHGFVLKDTAVTRFHEALATVSAGRSYLPHEVATKIAMLNAGL
LESPLARLTAREVQVLSLLGAGKSNEAIADSLSMSQRSVSAVVSGMKQKLGAGSLADLLRIALSRDGRPV
>Mature_229_residues
SAARASADRPAGRDGPRGLDAVLIVDDHPVVRRGFRHLAEDAGVRAVHEAADVVSGYRTFHRHRPGLVVTDLGFRDQGLS
GLSLIRRVRALEPATRILAFSMHDDPVIVARAIEGGAHGFVLKDTAVTRFHEALATVSAGRSYLPHEVATKIAMLNAGLL
ESPLARLTAREVQVLSLLGAGKSNEAIADSLSMSQRSVSAVVSGMKQKLGAGSLADLLRIALSRDGRPV

Specific function: Member of the two-component regulatory system moxY/moxX probably involved in the regulation of the methanol dehydrogenase expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=29.126213592233, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=28.0193236714976, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=32.6530612244898, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788546, Length=191, Percent_Identity=28.7958115183246, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788712, Length=199, Percent_Identity=24.6231155778894, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790102, Length=205, Percent_Identity=28.780487804878, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24414; Mature: 24283

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAARASADRPAGRDGPRGLDAVLIVDDHPVVRRGFRHLAEDAGVRAVHEAADVVSGYRT
CCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FHRHRPGLVVTDLGFRDQGLSGLSLIRRVRALEPATRILAFSMHDDPVIVARAIEGGAHG
HHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHEEEECCCCCEEEEEEECCCCCC
FVLKDTAVTRFHEALATVSAGRSYLPHEVATKIAMLNAGLLESPLARLTAREVQVLSLLG
EEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
AGKSNEAIADSLSMSQRSVSAVVSGMKQKLGAGSLADLLRIALSRDGRPV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SAARASADRPAGRDGPRGLDAVLIVDDHPVVRRGFRHLAEDAGVRAVHEAADVVSGYRT
CCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FHRHRPGLVVTDLGFRDQGLSGLSLIRRVRALEPATRILAFSMHDDPVIVARAIEGGAHG
HHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHEEEECCCCCEEEEEEECCCCCC
FVLKDTAVTRFHEALATVSAGRSYLPHEVATKIAMLNAGLLESPLARLTAREVQVLSLLG
EEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
AGKSNEAIADSLSMSQRSVSAVVSGMKQKLGAGSLADLLRIALSRDGRPV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8392137 [H]