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The map label for this gene is ftsK [H]

Identifier: 170750513

GI number: 170750513

Start: 4372639

End: 4375347

Strand: Reverse

Name: ftsK [H]

Synonym: Mrad2831_4120

Alternate gene names: 170750513

Gene position: 4375347-4372639 (Counterclockwise)

Preceding gene: 170750516

Following gene: 170750512

Centisome position: 71.99

GC content: 73.61

Gene sequence:

>2709_bases
GTGCCTAGCCTCGGGGGTAAGTTCCCGTTTCGCGTCCGGTCCCGCATGCGCTCGCTTCGCCGTCCCGCATCGCCCTACGA
GACTTTCGTCGACAGCGTTCGCCCGTTCCTGGGCAAGCGCCTGACGGAGCTCGGCGGCTTCGTGCTGTTCACCGGCGCGG
TCGCCCTGACCGTGGCGCTGGCCACGTGGTCGATCGACGACCCGAGCCTGAACCACGCCACCGACCACGCCGCCCACAAC
GTCCTCGGCCAGCCGGGCGCCGTCGTGGCCGATCTCGCCATGCAGATCCTGGGCCTGGGCTCCCTGGCCTTCGTGCTGCC
GCCGGTCCTCTGGGGCATCCGGCTGATGCGGGAGCGCGACCTGCCCGAGGGCGGCCTGCGCATCGCGCTCTGGATCATCG
GCTTCTGCGCCGCCAGCGCGGTGGCGAGCGCGCTCCCGCCGACGACCCGCTGGCCGCTGCCCACCGGCCTCGGCGGCGTG
GCCGGCGACGGCCTGCTGTCGATGGCGCGGGTGATCGTCGGCGCGGTCTCGTCGGCGGCGGCCCACCTCGTCGGCTTCGG
CTACGCCGCGGTGGCGATCCTCAGCCTGACCGGCGCCTGCCGATTCGGCGCCGTCGAGGAGGAACCCCTGCACGACGACC
CCTACCCCGTCCGGCGCGCGCCGGCGCGGGGCCGGGATTCGGGCCGGGACGAGCGCGAGGATTCCGACGAGCCGAGCCTC
GGCCTCGTCGGTGTCGGCGCCCTGGCGCAGGGGCTGATGGGCCTGCGCGGCGCCGCGGCCGAGCGGATCGCCGCGTGGCG
CGCGGGCCGGGCCGAGCCGATCGACGGCGCGTCGCCCGCCCTCGCGGCCCGCCGCGCCTTCACGGACGCCGATCTCCCCT
GGGCCGACCACCTGCCCGAGGGCCGGCAGGCCGGCGCGAGCCGGCGCGAGCCCGTCTTCGACGCCTCCGAGGACGCCACC
GCGGCGCCGGCCCGCCGCGCCGCGCCGCCGCGGGACGACGCGGAGGACGATCCGGACACGTTCGAGGCGCCGCAGCGCCC
GGTCCCGCCGCGGGCCGAGCCGACCGCGTCGCGGGTGGCCCCGCCGCCCGCCGCGCCCGTGCCGGCCCGGCGCGCGCCCG
CGCCGCCGGTCCGCCCCGAGGATTACGCCCTGCCCGCCCTCGACCTGCTGGCGGCCCCCCGCGGCCCGTCCCAGGCGAGC
CTGATCTCGGCCGATGCCCTGGAGCAGAACGCCACGCTGCTGGAGGCGACGCTCGGCGATTTCGGCGTGCGCGGCGACAT
CCTGGCGGTGCGGCCGGGCCCGGTCGTCACCCTCTACGAGCTCGAGCCCGCCCCCGGCACCAAGTCCAGCCGCGTGATCG
CGCTCGCCGACGACATCGCCCGGTCGATGTCGGCGGTCTCGGCCCGCGTCGCGGTCGTGCCCGGCCGGAACGCCATCGGC
ATCGAGCTGCCGAACGCCAAGCGCGAGACGGTGTACCTGCGCGAACTCCTGGCCTCGACGGACTTCGCCGAGAGCAAGCA
CAAGCTGGCTTTGTGCCTCGGCAAGAACATCGGCGGCGAGCCGATCATCGCCGACCTCGCGCGCATGCCGCACCTGCTGG
TGGCCGGCACCACCGGCTCGGGCAAGTCGGTGGCGATCAACACCATGATCCTCAGCCTGCTCTACCGGCTCAAGCCGGAG
GAGTGCCGCCTGATCATGGTCGACCCGAAGATGCTGGAGCTGTCGGTCTACGACGGCATCCCGCACCTGCTCTCCCCCGT
GGTCACCGACCCCAAGAAGGCGGTCATCGCCCTCAAGTGGGCCGTGCGCGAGATGGAGGAGCGCTACAAGAAGATGGCCA
AGATCGCGGTGCGCAACATCGACGGCTACAACGCCCGGGTCGCCGAGGCGGCGGCGCGCGGCGAGGTGCTGACCCGGACC
GTCCAGACCGGCTTCGACCGCCACACCGGCGAGGCGGTGTACGAGGACGAGGCGATGGACCTGGCGCCGCTGCCGTACAT
CGTGATCGTGGTCGACGAGATGGCCGACCTGATGATGGTGGCCGGCAAGGACATCGAGGGGGCGATCCAGCGTCTGGCGC
AGATGGCGCGGGCGGCGGGCATCCACCTGATCATGGCCACGCAGCGGCCGTCGGTGGACGTGATCACCGGCACGATCAAG
GCGAACTTCCCGACCCGGATCAGCTTCCAGGTGACGAGCAAGATCGACAGCCGCACGATCCTGGGCGAGATGGGCGCCGA
GCAGCTTCTGGGCCAGGGCGACATGCTGTTCATGGCCGGCGGCGGGCGCACGACGCGCGTGCACGGGCCGTTCTGCTCGG
ACAGCGAGGTCGAGAGCGTGGTCGCCCACCTCAAGCGCCAGGGCCGCCCCAGCTACCTCGACGCCGTCACCGCCGACGAC
GAGGAGGGCGCGTCCGAGAAGGGCGGCGAGCGCGGCGGGAAGGGCAAGGCCGGCGCCGCGGAACTCGAACTCGACGGCGC
GGTGTTCGACCAGGGCTCCTTCGGCGAGGCCGGCGGCGACCTCTACGACCAGGCCGTGCAGGTGGTGCTGCGCGACCAGA
AGGCGTCGACGAGCTACATCCAGCGCCGCCTGCAGATCGGCTACAACCGCGCCGCCTCCATCATGGAGCGGATGGAGATC
GAGGGCATCGTCGGCCCGGCCAACCACGCCGGCAAGCGCGAGATCCTCGTGGAGGAGGCGGTCGGCTGA

Upstream 100 bases:

>100_bases
CGGCTTTTGCATCCTCCCGGGCGCCGGCGCGACGGCCTGGGGATGCCCCGCCCGGCGGCCGGTCAGCCTTCCTCAACCTT
AGCGGGTCGTTAAGGCGCTC

Downstream 100 bases:

>100_bases
GAGCGGGGCCTGTGGCGTCCGCGGCGCCCCCCTCCCCTGCCGCCTGGGCAGGTTCGAGGCGCTGTCTGTGATGGAGCGCC
CCTCGCCCCGGCGAGGGCGG

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 902; Mature: 901

Protein sequence:

>902_residues
MPSLGGKFPFRVRSRMRSLRRPASPYETFVDSVRPFLGKRLTELGGFVLFTGAVALTVALATWSIDDPSLNHATDHAAHN
VLGQPGAVVADLAMQILGLGSLAFVLPPVLWGIRLMRERDLPEGGLRIALWIIGFCAASAVASALPPTTRWPLPTGLGGV
AGDGLLSMARVIVGAVSSAAAHLVGFGYAAVAILSLTGACRFGAVEEEPLHDDPYPVRRAPARGRDSGRDEREDSDEPSL
GLVGVGALAQGLMGLRGAAAERIAAWRAGRAEPIDGASPALAARRAFTDADLPWADHLPEGRQAGASRREPVFDASEDAT
AAPARRAAPPRDDAEDDPDTFEAPQRPVPPRAEPTASRVAPPPAAPVPARRAPAPPVRPEDYALPALDLLAAPRGPSQAS
LISADALEQNATLLEATLGDFGVRGDILAVRPGPVVTLYELEPAPGTKSSRVIALADDIARSMSAVSARVAVVPGRNAIG
IELPNAKRETVYLRELLASTDFAESKHKLALCLGKNIGGEPIIADLARMPHLLVAGTTGSGKSVAINTMILSLLYRLKPE
ECRLIMVDPKMLELSVYDGIPHLLSPVVTDPKKAVIALKWAVREMEERYKKMAKIAVRNIDGYNARVAEAAARGEVLTRT
VQTGFDRHTGEAVYEDEAMDLAPLPYIVIVVDEMADLMMVAGKDIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIK
ANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLFMAGGGRTTRVHGPFCSDSEVESVVAHLKRQGRPSYLDAVTADD
EEGASEKGGERGGKGKAGAAELELDGAVFDQGSFGEAGGDLYDQAVQVVLRDQKASTSYIQRRLQIGYNRAASIMERMEI
EGIVGPANHAGKREILVEEAVG

Sequences:

>Translated_902_residues
MPSLGGKFPFRVRSRMRSLRRPASPYETFVDSVRPFLGKRLTELGGFVLFTGAVALTVALATWSIDDPSLNHATDHAAHN
VLGQPGAVVADLAMQILGLGSLAFVLPPVLWGIRLMRERDLPEGGLRIALWIIGFCAASAVASALPPTTRWPLPTGLGGV
AGDGLLSMARVIVGAVSSAAAHLVGFGYAAVAILSLTGACRFGAVEEEPLHDDPYPVRRAPARGRDSGRDEREDSDEPSL
GLVGVGALAQGLMGLRGAAAERIAAWRAGRAEPIDGASPALAARRAFTDADLPWADHLPEGRQAGASRREPVFDASEDAT
AAPARRAAPPRDDAEDDPDTFEAPQRPVPPRAEPTASRVAPPPAAPVPARRAPAPPVRPEDYALPALDLLAAPRGPSQAS
LISADALEQNATLLEATLGDFGVRGDILAVRPGPVVTLYELEPAPGTKSSRVIALADDIARSMSAVSARVAVVPGRNAIG
IELPNAKRETVYLRELLASTDFAESKHKLALCLGKNIGGEPIIADLARMPHLLVAGTTGSGKSVAINTMILSLLYRLKPE
ECRLIMVDPKMLELSVYDGIPHLLSPVVTDPKKAVIALKWAVREMEERYKKMAKIAVRNIDGYNARVAEAAARGEVLTRT
VQTGFDRHTGEAVYEDEAMDLAPLPYIVIVVDEMADLMMVAGKDIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIK
ANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLFMAGGGRTTRVHGPFCSDSEVESVVAHLKRQGRPSYLDAVTADD
EEGASEKGGERGGKGKAGAAELELDGAVFDQGSFGEAGGDLYDQAVQVVLRDQKASTSYIQRRLQIGYNRAASIMERMEI
EGIVGPANHAGKREILVEEAVG
>Mature_901_residues
PSLGGKFPFRVRSRMRSLRRPASPYETFVDSVRPFLGKRLTELGGFVLFTGAVALTVALATWSIDDPSLNHATDHAAHNV
LGQPGAVVADLAMQILGLGSLAFVLPPVLWGIRLMRERDLPEGGLRIALWIIGFCAASAVASALPPTTRWPLPTGLGGVA
GDGLLSMARVIVGAVSSAAAHLVGFGYAAVAILSLTGACRFGAVEEEPLHDDPYPVRRAPARGRDSGRDEREDSDEPSLG
LVGVGALAQGLMGLRGAAAERIAAWRAGRAEPIDGASPALAARRAFTDADLPWADHLPEGRQAGASRREPVFDASEDATA
APARRAAPPRDDAEDDPDTFEAPQRPVPPRAEPTASRVAPPPAAPVPARRAPAPPVRPEDYALPALDLLAAPRGPSQASL
ISADALEQNATLLEATLGDFGVRGDILAVRPGPVVTLYELEPAPGTKSSRVIALADDIARSMSAVSARVAVVPGRNAIGI
ELPNAKRETVYLRELLASTDFAESKHKLALCLGKNIGGEPIIADLARMPHLLVAGTTGSGKSVAINTMILSLLYRLKPEE
CRLIMVDPKMLELSVYDGIPHLLSPVVTDPKKAVIALKWAVREMEERYKKMAKIAVRNIDGYNARVAEAAARGEVLTRTV
QTGFDRHTGEAVYEDEAMDLAPLPYIVIVVDEMADLMMVAGKDIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKA
NFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLFMAGGGRTTRVHGPFCSDSEVESVVAHLKRQGRPSYLDAVTADDE
EGASEKGGERGGKGKAGAAELELDGAVFDQGSFGEAGGDLYDQAVQVVLRDQKASTSYIQRRLQIGYNRAASIMERMEIE
GIVGPANHAGKREILVEEAVG

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=534, Percent_Identity=51.87265917603, Blast_Score=509, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 95714; Mature: 95582

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLGGKFPFRVRSRMRSLRRPASPYETFVDSVRPFLGKRLTELGGFVLFTGAVALTVAL
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ATWSIDDPSLNHATDHAAHNVLGQPGAVVADLAMQILGLGSLAFVLPPVLWGIRLMRERD
HHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
LPEGGLRIALWIIGFCAASAVASALPPTTRWPLPTGLGGVAGDGLLSMARVIVGAVSSAA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AHLVGFGYAAVAILSLTGACRFGAVEEEPLHDDPYPVRRAPARGRDSGRDEREDSDEPSL
HHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GLVGVGALAQGLMGLRGAAAERIAAWRAGRAEPIDGASPALAARRAFTDADLPWADHLPE
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCC
GRQAGASRREPVFDASEDATAAPARRAAPPRDDAEDDPDTFEAPQRPVPPRAEPTASRVA
HHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
PPPAAPVPARRAPAPPVRPEDYALPALDLLAAPRGPSQASLISADALEQNATLLEATLGD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHC
FGVRGDILAVRPGPVVTLYELEPAPGTKSSRVIALADDIARSMSAVSARVAVVPGRNAIG
CCCCCCEEEECCCCEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHEEEEEECCCCEEE
IELPNAKRETVYLRELLASTDFAESKHKLALCLGKNIGGEPIIADLARMPHLLVAGTTGS
EECCCCCHHHHHHHHHHHHCCCHHCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEECCCC
GKSVAINTMILSLLYRLKPEECRLIMVDPKMLELSVYDGIPHLLSPVVTDPKKAVIALKW
CCEEHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHCCCHHHHHHHHCCCCHHHHHHHH
AVREMEERYKKMAKIAVRNIDGYNARVAEAAARGEVLTRTVQTGFDRHTGEAVYEDEAMD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCC
LAPLPYIVIVVDEMADLMMVAGKDIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIK
CCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEE
ANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLFMAGGGRTTRVHGPFCSDSEVESV
ECCCCEEEEEEECCCCCHHHHHHHCHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHHH
VAHLKRQGRPSYLDAVTADDEEGASEKGGERGGKGKAGAAELELDGAVFDQGSFGEAGGD
HHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCH
LYDQAVQVVLRDQKASTSYIQRRLQIGYNRAASIMERMEIEGIVGPANHAGKREILVEEA
HHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHC
VG
CC
>Mature Secondary Structure 
PSLGGKFPFRVRSRMRSLRRPASPYETFVDSVRPFLGKRLTELGGFVLFTGAVALTVAL
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ATWSIDDPSLNHATDHAAHNVLGQPGAVVADLAMQILGLGSLAFVLPPVLWGIRLMRERD
HHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
LPEGGLRIALWIIGFCAASAVASALPPTTRWPLPTGLGGVAGDGLLSMARVIVGAVSSAA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AHLVGFGYAAVAILSLTGACRFGAVEEEPLHDDPYPVRRAPARGRDSGRDEREDSDEPSL
HHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GLVGVGALAQGLMGLRGAAAERIAAWRAGRAEPIDGASPALAARRAFTDADLPWADHLPE
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCC
GRQAGASRREPVFDASEDATAAPARRAAPPRDDAEDDPDTFEAPQRPVPPRAEPTASRVA
HHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
PPPAAPVPARRAPAPPVRPEDYALPALDLLAAPRGPSQASLISADALEQNATLLEATLGD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHC
FGVRGDILAVRPGPVVTLYELEPAPGTKSSRVIALADDIARSMSAVSARVAVVPGRNAIG
CCCCCCEEEECCCCEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHEEEEEECCCCEEE
IELPNAKRETVYLRELLASTDFAESKHKLALCLGKNIGGEPIIADLARMPHLLVAGTTGS
EECCCCCHHHHHHHHHHHHCCCHHCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEECCCC
GKSVAINTMILSLLYRLKPEECRLIMVDPKMLELSVYDGIPHLLSPVVTDPKKAVIALKW
CCEEHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHCCCHHHHHHHHCCCCHHHHHHHH
AVREMEERYKKMAKIAVRNIDGYNARVAEAAARGEVLTRTVQTGFDRHTGEAVYEDEAMD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCC
LAPLPYIVIVVDEMADLMMVAGKDIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIK
CCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEE
ANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLFMAGGGRTTRVHGPFCSDSEVESV
ECCCCEEEEEEECCCCCHHHHHHHCHHHHHCCCCEEEEECCCCEEEECCCCCCCHHHHHH
VAHLKRQGRPSYLDAVTADDEEGASEKGGERGGKGKAGAAELELDGAVFDQGSFGEAGGD
HHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCH
LYDQAVQVVLRDQKASTSYIQRRLQIGYNRAASIMERMEIEGIVGPANHAGKREILVEEA
HHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHC
VG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]