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The map label for this gene is holA

Identifier: 170750489

GI number: 170750489

Start: 4347938

End: 4348975

Strand: Reverse

Name: holA

Synonym: Mrad2831_4096

Alternate gene names: NA

Gene position: 4348975-4347938 (Counterclockwise)

Preceding gene: 170750490

Following gene: 170750483

Centisome position: 71.55

GC content: 75.05

Gene sequence:

>1038_bases
GTGACGGCAGTCAAGGCCGGCGAGATCGAGGGGCTGATCCGGCGCGGGCCCGATCCGCGCATCCCCGTCATCCTGGTCTT
CGGGCCGGATACCGGTCTGGTGACCGAGCGGGCCCGGAAGCTCGCCGAGGATTTCGTCGACGATCCGGCCGATCCGTTCG
CGCTGGTGCGGATCGACGGCGACGCCCTGGCCGCCGATCCGGGCCGGCTGTGCGACGAGGCCGGGACGATGGGCCTGTTC
GGCGGCCGCCGGTCGATCTGGGTCCGGCCCGGCACGCGCAACTACGCGCCCGCCGTCGAGGCGGTGCTGGGCGCGACCGT
CGCCGACGCCCGCATCGTGGTGGAGGCCGGCGACCTCGCCAAGAACAACCCGCTCCGCGCCCTCTGCGAGCGCTCGCCGA
AGGCGCTCGCGATCCCCTGCTACGCCGACGACGAGCGGACCCTCTCGGACCTGATCGAGCGCACCCTCCAGGAGCGCGGC
CTGCGCATCGACCGCGCCGCCCGGGAGGTCCTGGCCCGCAGCCTCGGCGGCGACCGTCGCGCGAGCCTGATGGAGATCGA
GAAGCTCGCCCTCTACGCCGCGGGGGAGGGGGACAAGACCGTGACCCTCGAGCACGTCGAGGCCGTCACCAGCGACGTCG
CGGCGAGCGTGCTCAACACCCTGATCGACGCCGCCTTCGACGGCCGCCGCGAGGCGGTGGAGCGCGACTACCGCCGCTTC
CGGCACGAGGGCCTCGATCCGGGCGTGGTGCTGGGCTCGGCGCTGCGGCACGCCCTGACACTGCTCACCACCCGCCTCGA
CAATCCCGAGAAGACGCCCGCCATGATGGCCGCGACCTGGCGGGGCCTGCATTTCAAGCGCAAGGCCAGCATCGAGGGCC
AGCTCGGCGCGTGGCCGCCCGGCACCCTCCGCCAGGCCGTCGCGGCCCTGCAGGAGGCCGTCCTCGCCTGCCGGCGGGCC
GAGCCCGACCTGGCCCACGCGCTGGCCTCGGCGGCCCTCCTGCGGGTCGCGGAGGCGGGGGCGCGGCGGCGGCGCTAG

Upstream 100 bases:

>100_bases
GCGGGCGGCGCGGGACGCCGAGATCCGGCTGGCGAGCGTGCTGTCCGATCAGATCAAGAGCCGCCTCGCGGCCGTGCTCT
CGACGAAGCCGTAACCCGAC

Downstream 100 bases:

>100_bases
CCGGGCTCAGGCGCCGTCCGCGCCCCCGGCACGGCGGCGCGCGAGCCACGCGCCCCAGAACAGGCTGGAGAAGAAGCGGG
TCGGCGTCCCGAAGCCGGCG

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Delta Subunit; DNA Polymerase II; DNA Polymerase III Delta

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTAVKAGEIEGLIRRGPDPRIPVILVFGPDTGLVTERARKLAEDFVDDPADPFALVRIDGDALAADPGRLCDEAGTMGLF
GGRRSIWVRPGTRNYAPAVEAVLGATVADARIVVEAGDLAKNNPLRALCERSPKALAIPCYADDERTLSDLIERTLQERG
LRIDRAAREVLARSLGGDRRASLMEIEKLALYAAGEGDKTVTLEHVEAVTSDVAASVLNTLIDAAFDGRREAVERDYRRF
RHEGLDPGVVLGSALRHALTLLTTRLDNPEKTPAMMAATWRGLHFKRKASIEGQLGAWPPGTLRQAVAALQEAVLACRRA
EPDLAHALASAALLRVAEAGARRRR

Sequences:

>Translated_345_residues
MTAVKAGEIEGLIRRGPDPRIPVILVFGPDTGLVTERARKLAEDFVDDPADPFALVRIDGDALAADPGRLCDEAGTMGLF
GGRRSIWVRPGTRNYAPAVEAVLGATVADARIVVEAGDLAKNNPLRALCERSPKALAIPCYADDERTLSDLIERTLQERG
LRIDRAAREVLARSLGGDRRASLMEIEKLALYAAGEGDKTVTLEHVEAVTSDVAASVLNTLIDAAFDGRREAVERDYRRF
RHEGLDPGVVLGSALRHALTLLTTRLDNPEKTPAMMAATWRGLHFKRKASIEGQLGAWPPGTLRQAVAALQEAVLACRRA
EPDLAHALASAALLRVAEAGARRRR
>Mature_344_residues
TAVKAGEIEGLIRRGPDPRIPVILVFGPDTGLVTERARKLAEDFVDDPADPFALVRIDGDALAADPGRLCDEAGTMGLFG
GRRSIWVRPGTRNYAPAVEAVLGATVADARIVVEAGDLAKNNPLRALCERSPKALAIPCYADDERTLSDLIERTLQERGL
RIDRAAREVLARSLGGDRRASLMEIEKLALYAAGEGDKTVTLEHVEAVTSDVAASVLNTLIDAAFDGRREAVERDYRRFR
HEGLDPGVVLGSALRHALTLLTTRLDNPEKTPAMMAATWRGLHFKRKASIEGQLGAWPPGTLRQAVAALQEAVLACRRAE
PDLAHALASAALLRVAEAGARRRR

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 37266; Mature: 37135

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVKAGEIEGLIRRGPDPRIPVILVFGPDTGLVTERARKLAEDFVDDPADPFALVRIDG
CCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECC
DALAADPGRLCDEAGTMGLFGGRRSIWVRPGTRNYAPAVEAVLGATVADARIVVEAGDLA
CEECCCCHHHHHHCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCCC
KNNPLRALCERSPKALAIPCYADDERTLSDLIERTLQERGLRIDRAAREVLARSLGGDRR
CCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
ASLMEIEKLALYAAGEGDKTVTLEHVEAVTSDVAASVLNTLIDAAFDGRREAVERDYRRF
HHHHHHHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RHEGLDPGVVLGSALRHALTLLTTRLDNPEKTPAMMAATWRGLHFKRKASIEGQLGAWPP
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCC
GTLRQAVAALQEAVLACRRAEPDLAHALASAALLRVAEAGARRRR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAVKAGEIEGLIRRGPDPRIPVILVFGPDTGLVTERARKLAEDFVDDPADPFALVRIDG
CCCCCHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECC
DALAADPGRLCDEAGTMGLFGGRRSIWVRPGTRNYAPAVEAVLGATVADARIVVEAGDLA
CEECCCCHHHHHHCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCCC
KNNPLRALCERSPKALAIPCYADDERTLSDLIERTLQERGLRIDRAAREVLARSLGGDRR
CCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
ASLMEIEKLALYAAGEGDKTVTLEHVEAVTSDVAASVLNTLIDAAFDGRREAVERDYRRF
HHHHHHHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RHEGLDPGVVLGSALRHALTLLTTRLDNPEKTPAMMAATWRGLHFKRKASIEGQLGAWPP
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCC
GTLRQAVAALQEAVLACRRAEPDLAHALASAALLRVAEAGARRRR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA