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The map label for this gene is rpoE [H]

Identifier: 170750421

GI number: 170750421

Start: 4270216

End: 4270812

Strand: Direct

Name: rpoE [H]

Synonym: Mrad2831_4026

Alternate gene names: 170750421

Gene position: 4270216-4270812 (Clockwise)

Preceding gene: 170750420

Following gene: 170750432

Centisome position: 70.26

GC content: 72.19

Gene sequence:

>597_bases
ATGACCCTGATGCTGCAAGCCGCTCCCGCGGGGAGCGGGTCCGGTCCGGTGCCCCGGGGCGCCGACGCCGAGATGCGCGA
CCTCCTGCTGGGAGCGATCCCGGCGCTGCGGGCCTTCGCGTTCTCGCTGACCTACGACCTCGACCGCTCGGACGATCTCG
TGCAGGACACGCTCGTGCGCGCCTGGGTCAACGCCGCCAGCTTCCGCCGCGGGACCAACCTGACCGCGTGGCTGTTCACG
ATCCTGCGGAACCTGTTCTACTCGGAGCAGCGCAAGCGCAAGCGCGAGGTCGAGGATGCCGACGGCGTCCATGCCGGGCG
CCTGACCGCCCTCCCCGAGCAGGAGATCCGGATGGAGATGGCGCAGTTCCAGAGCGCGCTGAACCAGCTGCCGCCGGCCC
AGCGCGAGGCGCTGGTCCTGGTCGGCGCCCAGAGCTTCACCTACGAGGAGGCCGCGGCCATCTGCGGCGTGGCGGTGGGC
ACGATCAAGAGCCGGGTCAGCCGCGCCCGGACCCGCCTGATCGAGGTGCTGGGCATGACCGGCACCGACGATATCGGGCC
CGACCCGCAGACCCGCGCGGCCCTCGACGGCCCCTGA

Upstream 100 bases:

>100_bases
TGCGCCTGCACTACGCCGGCGTCCTGGCCCTGCCGATTCCGGACCGGCTCCGGACGCTGCTCGACGAGCTCGCCGCCCAC
TCCGACACGGAGGCCTCGCG

Downstream 100 bases:

>100_bases
GGCGCGCTCCGCAGCGGGACCCGGACGCCGCCCCGGCGCCTACTTGATGAGCCTCACCACGTCGCGGAACCGCCTGTGTC
GCGCCGTGCCGAGCCACTCG

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTLMLQAAPAGSGSGPVPRGADAEMRDLLLGAIPALRAFAFSLTYDLDRSDDLVQDTLVRAWVNAASFRRGTNLTAWLFT
ILRNLFYSEQRKRKREVEDADGVHAGRLTALPEQEIRMEMAQFQSALNQLPPAQREALVLVGAQSFTYEEAAAICGVAVG
TIKSRVSRARTRLIEVLGMTGTDDIGPDPQTRAALDGP

Sequences:

>Translated_198_residues
MTLMLQAAPAGSGSGPVPRGADAEMRDLLLGAIPALRAFAFSLTYDLDRSDDLVQDTLVRAWVNAASFRRGTNLTAWLFT
ILRNLFYSEQRKRKREVEDADGVHAGRLTALPEQEIRMEMAQFQSALNQLPPAQREALVLVGAQSFTYEEAAAICGVAVG
TIKSRVSRARTRLIEVLGMTGTDDIGPDPQTRAALDGP
>Mature_197_residues
TLMLQAAPAGSGSGPVPRGADAEMRDLLLGAIPALRAFAFSLTYDLDRSDDLVQDTLVRAWVNAASFRRGTNLTAWLFTI
LRNLFYSEQRKRKREVEDADGVHAGRLTALPEQEIRMEMAQFQSALNQLPPAQREALVLVGAQSFTYEEAAAICGVAVGT
IKSRVSRARTRLIEVLGMTGTDDIGPDPQTRAALDGP

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014293
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21531; Mature: 21400

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLMLQAAPAGSGSGPVPRGADAEMRDLLLGAIPALRAFAFSLTYDLDRSDDLVQDTLVR
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AWVNAASFRRGTNLTAWLFTILRNLFYSEQRKRKREVEDADGVHAGRLTALPEQEIRMEM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
AQFQSALNQLPPAQREALVLVGAQSFTYEEAAAICGVAVGTIKSRVSRARTRLIEVLGMT
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GTDDIGPDPQTRAALDGP
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLMLQAAPAGSGSGPVPRGADAEMRDLLLGAIPALRAFAFSLTYDLDRSDDLVQDTLVR
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AWVNAASFRRGTNLTAWLFTILRNLFYSEQRKRKREVEDADGVHAGRLTALPEQEIRMEM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
AQFQSALNQLPPAQREALVLVGAQSFTYEEAAAICGVAVGTIKSRVSRARTRLIEVLGMT
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GTDDIGPDPQTRAALDGP
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]