BacMap

Definition	Methylobacterium radiotolerans JCM 2831 chromosome, complete genome.
Accession	NC_010505
Length	6,077,833

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The map label for this gene is ucpA [C]

Identifier: 170750418

GI number: 170750418

Start: 4268346

End: 4269104

Strand: Direct

Name: ucpA [C]

Synonym: Mrad2831_4023

Alternate gene names: 170750418

Gene position: 4268346-4269104 (Clockwise)

Preceding gene: 170750417

Following gene: 170750420

Centisome position: 70.23

GC content: 74.04

Gene sequence:

>759_bases
ATGATGCGCGCGCTCGAAGGGCAGGTCGCCTGGGTGACGGGGGCCGGATCCGGCATCGGGCAGGCGGCCGCCCTGGCGCT
GGCGCGGGCCGGGATGCGGCTCGCGCTCACGGGACGGGGGCGGGAGGCCCTCGCGCGCACCGCGGAGCTCGTCCGCGCGG
CGGGCGGCGAGGCGCTGGTCGTCCCGGCCGACATGGGCGTGGCCGGCGACGTGCAGCGCGCCTGGGAGACGGTTCACGCC
GCGTGGCGGCGCTGCGACCTGCTGGTGAACGCGGCGGGCCTCAACGTGCCTCAGCGCGGCTGGAGCGAGATCACGCCGGC
CGGCATCGACGCCGTGGTCGGCGTCAATCTCAACGGCCCCTTCTACGCGGCGCGGGCGGTGCTGCCGACCATGCGGGCGC
AGCGGGGCGGCCTGATCATCCACGTCTCCTCCTGGGCCGGCCGCTACGTCTCCAAGCTGACGGGGCCGGCCTATTCCGCC
GCCAAGCACGGGCTCGTGGCGCTCTCCGAGAGCCTGAACCAGGAGGAGTGCGGGCACGGCATCCGGTCCTGCTGCATCTG
CCCGGGCGAGGTCGCGACGCCCCTCCTCGACAAGCGGCCGGTTCCGGTCACCGCGGAGGACCGCGGGCGCATGCTGCAGG
CGGAGGATCTCGCCGAGACGATCCTGTTCGTCGCCCGCCTGCCGGCCTCCGTCTGCGTCAACGAGATCCTGATCAGCCCC
ACCTGGAATCGCGGCTATCTCGAGGGCGTGAAGCTCTGA

Upstream 100 bases:

>100_bases
ACGAGCTCCTCGACACGATCCCCGCCGAGCAGGCCTTCCGCCCCCTGGCCGAGGGCGGCTGCCCGCTCGTCGCCAAGCCG
TAGGGACGGGGCCGAAAGCC

Downstream 100 bases:

>100_bases
GCGGTGCCGTCCCGGCGCGCTCGGACGGCGCGCGATCCGCGCGCGGGAGCCGCCGGCGCGGAGGACGCGGATCACGGACC
CGGCGTCGAGGCGGGTCGCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MMRALEGQVAWVTGAGSGIGQAAALALARAGMRLALTGRGREALARTAELVRAAGGEALVVPADMGVAGDVQRAWETVHA
AWRRCDLLVNAAGLNVPQRGWSEITPAGIDAVVGVNLNGPFYAARAVLPTMRAQRGGLIIHVSSWAGRYVSKLTGPAYSA
AKHGLVALSESLNQEECGHGIRSCCICPGEVATPLLDKRPVPVTAEDRGRMLQAEDLAETILFVARLPASVCVNEILISP
TWNRGYLEGVKL

Sequences:

>Translated_252_residues
MMRALEGQVAWVTGAGSGIGQAAALALARAGMRLALTGRGREALARTAELVRAAGGEALVVPADMGVAGDVQRAWETVHA
AWRRCDLLVNAAGLNVPQRGWSEITPAGIDAVVGVNLNGPFYAARAVLPTMRAQRGGLIIHVSSWAGRYVSKLTGPAYSA
AKHGLVALSESLNQEECGHGIRSCCICPGEVATPLLDKRPVPVTAEDRGRMLQAEDLAETILFVARLPASVCVNEILISP
TWNRGYLEGVKL
>Mature_252_residues
MMRALEGQVAWVTGAGSGIGQAAALALARAGMRLALTGRGREALARTAELVRAAGGEALVVPADMGVAGDVQRAWETVHA
AWRRCDLLVNAAGLNVPQRGWSEITPAGIDAVVGVNLNGPFYAARAVLPTMRAQRGGLIIHVSSWAGRYVSKLTGPAYSA
AKHGLVALSESLNQEECGHGIRSCCICPGEVATPLLDKRPVPVTAEDRGRMLQAEDLAETILFVARLPASVCVNEILISP
TWNRGYLEGVKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=246, Percent_Identity=30.4878048780488, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI40254992, Length=235, Percent_Identity=32.3404255319149, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=33.160621761658, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503817, Length=222, Percent_Identity=26.5765765765766, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI142976729, Length=201, Percent_Identity=27.8606965174129, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI15277342, Length=243, Percent_Identity=30.4526748971193, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31542939, Length=216, Percent_Identity=29.6296296296296, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7706318, Length=200, Percent_Identity=31, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=31.1538461538462, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=31.5270935960591, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI66933014, Length=261, Percent_Identity=29.8850574712644, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=27.3858921161826, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=195, Percent_Identity=32.3076923076923, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40807363, Length=200, Percent_Identity=27.5, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI25282469, Length=222, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI209862901, Length=211, Percent_Identity=31.7535545023697, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI19923983, Length=211, Percent_Identity=31.7535545023697, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=32.3076923076923, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI19923817, Length=196, Percent_Identity=29.5918367346939, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI59889578, Length=201, Percent_Identity=26.865671641791, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI87082100, Length=195, Percent_Identity=33.8461538461538, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=29.0836653386454, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=28.0487804878049, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=30.2788844621514, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI2367175, Length=235, Percent_Identity=29.3617021276596, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789208, Length=191, Percent_Identity=31.413612565445, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787820, Length=242, Percent_Identity=27.6859504132231, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788459, Length=210, Percent_Identity=31.4285714285714, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=201, Percent_Identity=26.865671641791, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=28.2828282828283, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=29.7297297297297, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=200, Percent_Identity=28, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=216, Percent_Identity=31.0185185185185, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=30.5699481865285, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=199, Percent_Identity=29.1457286432161, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=234, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=28.8537549407115, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=249, Percent_Identity=29.3172690763052, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=29.2887029288703, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=27.8947368421053, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=199, Percent_Identity=29.1457286432161, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=29.1457286432161, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=247, Percent_Identity=25.9109311740891, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997099, Length=207, Percent_Identity=28.0193236714976, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=205, Percent_Identity=25.8536585365854, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=27.4074074074074, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=254, Percent_Identity=27.5590551181102, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=24.9027237354086, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=25.6603773584906, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=198, Percent_Identity=28.2828282828283, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=250, Percent_Identity=26.4, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=30.9278350515464, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=29.1497975708502, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324126, Length=261, Percent_Identity=26.0536398467433, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=33.469387755102, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=31.1224489795918, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=31.6872427983539, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI116007236, Length=247, Percent_Identity=29.1497975708502, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641232, Length=253, Percent_Identity=30.4347826086957, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24580925, Length=206, Percent_Identity=33.495145631068, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=35.0785340314136, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=31.4432989690722, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281364494, Length=251, Percent_Identity=28.2868525896414, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=197, Percent_Identity=32.994923857868, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=25.3968253968254, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=28.0851063829787, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640442, Length=206, Percent_Identity=31.5533980582524, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571526, Length=197, Percent_Identity=31.4720812182741, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI116007234, Length=249, Percent_Identity=29.718875502008, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641388, Length=253, Percent_Identity=31.6205533596838, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648693, Length=246, Percent_Identity=26.0162601626016, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355889, Length=246, Percent_Identity=26.0162601626016, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=29.7142857142857, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356301, Length=231, Percent_Identity=24.2424242424242, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26510; Mature: 26510

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRALEGQVAWVTGAGSGIGQAAALALARAGMRLALTGRGREALARTAELVRAAGGEALV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEE
VPADMGVAGDVQRAWETVHAAWRRCDLLVNAAGLNVPQRGWSEITPAGIDAVVGVNLNGP
EECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCC
FYAARAVLPTMRAQRGGLIIHVSSWAGRYVSKLTGPAYSAAKHGLVALSESLNQEECGHG
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCHHHHHHCCHHHHHHHCCHHHHCCH
IRSCCICPGEVATPLLDKRPVPVTAEDRGRMLQAEDLAETILFVARLPASVCVNEILISP
HHHHCCCCCHHHCHHHCCCCCCCCCCCCCCEECHHHHHHHHHHHHHCCHHHHHHHHHCCC
TWNRGYLEGVKL
CCCCCCCCCCCC
>Mature Secondary Structure
MMRALEGQVAWVTGAGSGIGQAAALALARAGMRLALTGRGREALARTAELVRAAGGEALV
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEE
VPADMGVAGDVQRAWETVHAAWRRCDLLVNAAGLNVPQRGWSEITPAGIDAVVGVNLNGP
EECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCC
FYAARAVLPTMRAQRGGLIIHVSSWAGRYVSKLTGPAYSAAKHGLVALSESLNQEECGHG
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCHHHHHHCCHHHHHHHCCHHHHCCH
IRSCCICPGEVATPLLDKRPVPVTAEDRGRMLQAEDLAETILFVARLPASVCVNEILISP
HHHHCCCCCHHHCHHHCCCCCCCCCCCCCCEECHHHHHHHHHHHHHCCHHHHHHHHHCCC
TWNRGYLEGVKL
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]