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The map label for this gene is feaR [H]

Identifier: 170750407

GI number: 170750407

Start: 4254994

End: 4255980

Strand: Reverse

Name: feaR [H]

Synonym: Mrad2831_4010

Alternate gene names: 170750407

Gene position: 4255980-4254994 (Counterclockwise)

Preceding gene: 170750408

Following gene: 170750406

Centisome position: 70.02

GC content: 66.26

Gene sequence:

>987_bases
ATGCAACCGCTTTTTTCGACAGAAAAGATCCACCCTCGGAACGCGTTCCGCCAGTGGCGCGAAATGGTCTGTGAACAGCT
GGTCCCGGTGGAGTTGAAGACCGTCGACGAGGCCCAGTTCAAGGGCAGCATAGCCGCTACGAATATCGGCGCCGTGCCGA
TTTCACACTTCGCACACACGGCCATGCGCAGCGAAACGACGGCCGACGCGGCCCGGCGCGACGACCGGTCCGATCGGGCC
TACGCGGTCCTGATGCTCTCCGGCCGGGCTATCGCCCGACAGGGCGACCAGGAGGCGGAATGTCAGATGGGCGACCTTTT
CGTCCTCGACGCACGCCCGGCCGTCGTCCAGACGGAGACGAGCAGTACCCTGATCCTGGATCTGCCGCGCGATCGTCTGG
AAACCGCACTGGGCCCGTCCCGGCTGTTCAGCGCCCTCAGGGTCGGCGCGGACCACGCCTCCACGACCTTGGCGCGGACG
TACATCCAGGATTTGGTTGCGGTCGCCGATCGGCTCGGCCCCGACGCGGCCGCCCGCTTGGCGTCGATCGGGATCGACCT
AATCGTAGCCAGCCTCGCCGAACGGATGGCGCAGGAGGTACCGCGTTCCATACACGGCAACGTCACGGTCCAGCGTGCCA
AGGCCTATGTTGAGACCCATCTGGGCGATCCGAGTTTGGATCCACCACAGCTCGCCGCCGCAATGGGGCTGTCGCTACGC
CGGCTGCAGGAGCTGTTCCACGAGCGCGGCCGGCACATCTCCGACTACATCTGGGAACGCCGCTTGGAGGTGGCAGCCAA
GCGCCTGACCGACCCGGCCTGTGCACACCTGTCCGTCGGCATGCTGGCCTACGCCTGTGGCTTCAGCAGCCAGGCGCATT
TCGCCCGCCGCTTCAAGGATCGCTACGACGTGAGCCCCCGTGAATACCGGCAGGCACACACGCAGGACCTGCGGTCGGTT
GCGACCGCTCTCGGGCTGTCGCCCTAG

Upstream 100 bases:

>100_bases
ATGCGAGCGATACGCACATGGTTGCAGCATATTATATACAATACGCGTCCGGACCTTCATTCCTCGCCACCGGGTGGTGT
CGGGGGCGCCTAGGCCTCAA

Downstream 100 bases:

>100_bases
CGGCTGAGTGACGGAAGCGGGTCGCTATCGGACTGTCTGCTCGGTGTGGAAGGGGGATGGGCCGCTTCGGAGCTGCGGAT
ACATCGGAGCAGACATGGCC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MQPLFSTEKIHPRNAFRQWREMVCEQLVPVELKTVDEAQFKGSIAATNIGAVPISHFAHTAMRSETTADAARRDDRSDRA
YAVLMLSGRAIARQGDQEAECQMGDLFVLDARPAVVQTETSSTLILDLPRDRLETALGPSRLFSALRVGADHASTTLART
YIQDLVAVADRLGPDAAARLASIGIDLIVASLAERMAQEVPRSIHGNVTVQRAKAYVETHLGDPSLDPPQLAAAMGLSLR
RLQELFHERGRHISDYIWERRLEVAAKRLTDPACAHLSVGMLAYACGFSSQAHFARRFKDRYDVSPREYRQAHTQDLRSV
ATALGLSP

Sequences:

>Translated_328_residues
MQPLFSTEKIHPRNAFRQWREMVCEQLVPVELKTVDEAQFKGSIAATNIGAVPISHFAHTAMRSETTADAARRDDRSDRA
YAVLMLSGRAIARQGDQEAECQMGDLFVLDARPAVVQTETSSTLILDLPRDRLETALGPSRLFSALRVGADHASTTLART
YIQDLVAVADRLGPDAAARLASIGIDLIVASLAERMAQEVPRSIHGNVTVQRAKAYVETHLGDPSLDPPQLAAAMGLSLR
RLQELFHERGRHISDYIWERRLEVAAKRLTDPACAHLSVGMLAYACGFSSQAHFARRFKDRYDVSPREYRQAHTQDLRSV
ATALGLSP
>Mature_328_residues
MQPLFSTEKIHPRNAFRQWREMVCEQLVPVELKTVDEAQFKGSIAATNIGAVPISHFAHTAMRSETTADAARRDDRSDRA
YAVLMLSGRAIARQGDQEAECQMGDLFVLDARPAVVQTETSSTLILDLPRDRLETALGPSRLFSALRVGADHASTTLART
YIQDLVAVADRLGPDAAARLASIGIDLIVASLAERMAQEVPRSIHGNVTVQRAKAYVETHLGDPSLDPPQLAAAMGLSLR
RLQELFHERGRHISDYIWERRLEVAAKRLTDPACAHLSVGMLAYACGFSSQAHFARRFKDRYDVSPREYRQAHTQDLRSV
ATALGLSP

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=307, Percent_Identity=26.7100977198697, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 36237; Mature: 36237

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPLFSTEKIHPRNAFRQWREMVCEQLVPVELKTVDEAQFKGSIAATNIGAVPISHFAHT
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHH
AMRSETTADAARRDDRSDRAYAVLMLSGRAIARQGDQEAECQMGDLFVLDARPAVVQTET
HHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCHHCCCCCCEEEEECCCCEEEECC
SSTLILDLPRDRLETALGPSRLFSALRVGADHASTTLARTYIQDLVAVADRLGPDAAARL
CCEEEEECCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ASIGIDLIVASLAERMAQEVPRSIHGNVTVQRAKAYVETHLGDPSLDPPQLAAAMGLSLR
HHHHHHHHHHHHHHHHHHHCCHHHCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RLQELFHERGRHISDYIWERRLEVAAKRLTDPACAHLSVGMLAYACGFSSQAHFARRFKD
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RYDVSPREYRQAHTQDLRSVATALGLSP
HCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQPLFSTEKIHPRNAFRQWREMVCEQLVPVELKTVDEAQFKGSIAATNIGAVPISHFAHT
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHH
AMRSETTADAARRDDRSDRAYAVLMLSGRAIARQGDQEAECQMGDLFVLDARPAVVQTET
HHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCHHCCCCCCEEEEECCCCEEEECC
SSTLILDLPRDRLETALGPSRLFSALRVGADHASTTLARTYIQDLVAVADRLGPDAAARL
CCEEEEECCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ASIGIDLIVASLAERMAQEVPRSIHGNVTVQRAKAYVETHLGDPSLDPPQLAAAMGLSLR
HHHHHHHHHHHHHHHHHHHCCHHHCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RLQELFHERGRHISDYIWERRLEVAAKRLTDPACAHLSVGMLAYACGFSSQAHFARRFKD
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RYDVSPREYRQAHTQDLRSVATALGLSP
HCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]