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The map label for this gene is pdxH [H]

Identifier: 170750344

GI number: 170750344

Start: 4199370

End: 4199993

Strand: Reverse

Name: pdxH [H]

Synonym: Mrad2831_3947

Alternate gene names: 170750344

Gene position: 4199993-4199370 (Counterclockwise)

Preceding gene: 170750346

Following gene: 170750335

Centisome position: 69.1

GC content: 71.79

Gene sequence:

>624_bases
GTGGATCAGTTAAGGACCGATGACCCGAAGAGCGCGGACTTCACGCTGAGCGAGGACCCCGTCGGGCTGTTCGCCGCCTG
GATGAAGGAGGCCGAGGCCTCCGAGCCCGAGGACGCGAACGCGATGGCGCTCGCCACCGCCGGATCGGACGGGCTGCCGG
ACGTGCGGATGGTCCTGTTGAAGGACTTCGACGCCCGCGGCTTCGTGTTCTACACCAACACCCAGTCCACCAAGGGCGAG
GAGCTGGCGCAGAACCCCCAGGCCGCCCTGGTGCTGCACTGGAAGAGCCTGCGCCGGCAGGTGCGGGCCCGCGGGCCGAT
CACGCCGGTCACGGCCGCGGAGGCCGACGCCTATTTCCAGAGCCGCCGCCGGGAGAGCCGCCTCGGTGCGATCGCCAGCC
AGCAATCCCGCCCGCTCGCGGACCGCGCCACGCTGATGTCGGCGGTGGCGGAGCTGTCCGAGCGCTACGGGGACGGGCCG
ATCCCCCGGCCTGAGCACTGGACCGGGTTCCGGATCGCGCCGGTGAGCGTCGAGTTCTGGCAGAACGGCGACTTCCGCCT
GCACGACCGCGTGCGCTTCACCCGGACGGGCGCGGGCTGGAGCCGGGCGCGGCTCTATCCCTGA

Upstream 100 bases:

>100_bases
CCCCGCATTACACCTGACTCACGACGGGCTATTCGCTCGACCGAACACGCCGATGTCGGTGCCCCCTCAGGCCCTGGACG
CGGCAGGCAGGAGTCTTGGC

Downstream 100 bases:

>100_bases
CCGCGGCCGAAACGCAGAGAGCCCCGGCAGGGCCGGGGCTCTCGCGTCGCGTGACAGGGAGCGACGAGGCTCAGGCCTCC
TCGCCGTCCTTCTTCTCGTC

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MDQLRTDDPKSADFTLSEDPVGLFAAWMKEAEASEPEDANAMALATAGSDGLPDVRMVLLKDFDARGFVFYTNTQSTKGE
ELAQNPQAALVLHWKSLRRQVRARGPITPVTAAEADAYFQSRRRESRLGAIASQQSRPLADRATLMSAVAELSERYGDGP
IPRPEHWTGFRIAPVSVEFWQNGDFRLHDRVRFTRTGAGWSRARLYP

Sequences:

>Translated_207_residues
MDQLRTDDPKSADFTLSEDPVGLFAAWMKEAEASEPEDANAMALATAGSDGLPDVRMVLLKDFDARGFVFYTNTQSTKGE
ELAQNPQAALVLHWKSLRRQVRARGPITPVTAAEADAYFQSRRRESRLGAIASQQSRPLADRATLMSAVAELSERYGDGP
IPRPEHWTGFRIAPVSVEFWQNGDFRLHDRVRFTRTGAGWSRARLYP
>Mature_207_residues
MDQLRTDDPKSADFTLSEDPVGLFAAWMKEAEASEPEDANAMALATAGSDGLPDVRMVLLKDFDARGFVFYTNTQSTKGE
ELAQNPQAALVLHWKSLRRQVRARGPITPVTAAEADAYFQSRRRESRLGAIASQQSRPLADRATLMSAVAELSERYGDGP
IPRPEHWTGFRIAPVSVEFWQNGDFRLHDRVRFTRTGAGWSRARLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=180, Percent_Identity=46.6666666666667, Blast_Score=167, Evalue=4e-42,
Organism=Escherichia coli, GI1787926, Length=192, Percent_Identity=39.5833333333333, Blast_Score=156, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17553712, Length=211, Percent_Identity=39.3364928909953, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6319509, Length=199, Percent_Identity=37.6884422110553, Blast_Score=133, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24644901, Length=207, Percent_Identity=36.7149758454106, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI45551845, Length=207, Percent_Identity=36.7149758454106, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24644903, Length=193, Percent_Identity=26.4248704663212, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 23126; Mature: 23126

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLRTDDPKSADFTLSEDPVGLFAAWMKEAEASEPEDANAMALATAGSDGLPDVRMVLL
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHH
KDFDARGFVFYTNTQSTKGEELAQNPQAALVLHWKSLRRQVRARGPITPVTAAEADAYFQ
HCCCCCEEEEEECCCCCCCHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHH
SRRRESRLGAIASQQSRPLADRATLMSAVAELSERYGDGPIPRPEHWTGFRIAPVSVEFW
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEE
QNGDFRLHDRVRFTRTGAGWSRARLYP
CCCCEEEECCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDQLRTDDPKSADFTLSEDPVGLFAAWMKEAEASEPEDANAMALATAGSDGLPDVRMVLL
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHH
KDFDARGFVFYTNTQSTKGEELAQNPQAALVLHWKSLRRQVRARGPITPVTAAEADAYFQ
HCCCCCEEEEEECCCCCCCHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHH
SRRRESRLGAIASQQSRPLADRATLMSAVAELSERYGDGPIPRPEHWTGFRIAPVSVEFW
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEE
QNGDFRLHDRVRFTRTGAGWSRARLYP
CCCCEEEECCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA