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The map label for this gene is 170750312

Identifier: 170750312

GI number: 170750312

Start: 4165888

End: 4166367

Strand: Reverse

Name: 170750312

Synonym: Mrad2831_3915

Alternate gene names: NA

Gene position: 4166367-4165888 (Counterclockwise)

Preceding gene: 170750313

Following gene: 170750311

Centisome position: 68.55

GC content: 69.38

Gene sequence:

>480_bases
ATGATCCAGGTCGGCGACCACCTGCCCCAGGCCACCTTCCGGGTGATCGGCCCCGAGGGCCCGATCGCGCGCACCACCGA
CGACGTGTTCAAGGGCCGGCGCGTGGTCCTGATCGGCGTGCCGGGCGCGTTCACCCCCAGCTGCCACCGCAACCACCTGC
CGGGCTTCGTCACCCACAGGGACGAGATCCTCGGGCGGGGCATCGACGCCATCGCGGTGACGAGCGTCAACGACGTGTTC
GTGCTCGACGCGTGGTCGAAGGCGAGCGGCGCCGAGGGGCTGGAATTCCTCGCCGACGGCAACGCCGATTTCGCCAAGGC
CATCGGCCTGGAGATGGACGGCACGGGCTTCGGTCTCGGGATGCGCTCGAAGCGCTACTCGATGCTGGTCGAGGACGGCG
TCGTCCGGATCCTCAACGTCGAGGAGACGCCCTCGAAGGCCGAGGTTTCCGGGGCCGAGGCCCTGCTGAAGGTCCTCTGA

Upstream 100 bases:

>100_bases
CGCAGGCTGCTCCCGATCCTCGACAGGCACCCCCTGCCACGCTAGGTCAGGCGCGCTGCTCACGCGCGCCATCCCAGCGC
GCGACAACGAGGGACCCGCG

Downstream 100 bases:

>100_bases
GCGCGCCGCGCGCCGCAGGGCGGCCCTCTTAAGGCCACGTTCCGTCCGCTTGTGTCGCCGGGCTCTGCCCGGAGACCGGC
CCGAGGACCGCATGGCCTTC

Product: redoxin domain-containing protein

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MIQVGDHLPQATFRVIGPEGPIARTTDDVFKGRRVVLIGVPGAFTPSCHRNHLPGFVTHRDEILGRGIDAIAVTSVNDVF
VLDAWSKASGAEGLEFLADGNADFAKAIGLEMDGTGFGLGMRSKRYSMLVEDGVVRILNVEETPSKAEVSGAEALLKVL

Sequences:

>Translated_159_residues
MIQVGDHLPQATFRVIGPEGPIARTTDDVFKGRRVVLIGVPGAFTPSCHRNHLPGFVTHRDEILGRGIDAIAVTSVNDVF
VLDAWSKASGAEGLEFLADGNADFAKAIGLEMDGTGFGLGMRSKRYSMLVEDGVVRILNVEETPSKAEVSGAEALLKVL
>Mature_159_residues
MIQVGDHLPQATFRVIGPEGPIARTTDDVFKGRRVVLIGVPGAFTPSCHRNHLPGFVTHRDEILGRGIDAIAVTSVNDVF
VLDAWSKASGAEGLEFLADGNADFAKAIGLEMDGTGFGLGMRSKRYSMLVEDGVVRILNVEETPSKAEVSGAEALLKVL

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=143, Percent_Identity=41.2587412587413, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6323138, Length=133, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI78706776, Length=143, Percent_Identity=46.1538461538462, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI78709078, Length=143, Percent_Identity=46.1538461538462, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR011906
- InterPro:   IPR014025
- InterPro:   IPR013740
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin; PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16946; Mature: 16946

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQVGDHLPQATFRVIGPEGPIARTTDDVFKGRRVVLIGVPGAFTPSCHRNHLPGFVTHR
CCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECH
DEILGRGIDAIAVTSVNDVFVLDAWSKASGAEGLEFLADGNADFAKAIGLEMDGTGFGLG
HHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHCCCEECCCCCCCC
MRSKRYSMLVEDGVVRILNVEETPSKAEVSGAEALLKVL
CCCCHHHEEECCCEEEEEECCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIQVGDHLPQATFRVIGPEGPIARTTDDVFKGRRVVLIGVPGAFTPSCHRNHLPGFVTHR
CCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECH
DEILGRGIDAIAVTSVNDVFVLDAWSKASGAEGLEFLADGNADFAKAIGLEMDGTGFGLG
HHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHCCCEECCCCCCCC
MRSKRYSMLVEDGVVRILNVEETPSKAEVSGAEALLKVL
CCCCHHHEEECCCEEEEEECCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]