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The map label for this gene is 170750262

Identifier: 170750262

GI number: 170750262

Start: 4113298

End: 4114446

Strand: Reverse

Name: 170750262

Synonym: Mrad2831_3865

Alternate gene names: NA

Gene position: 4114446-4113298 (Counterclockwise)

Preceding gene: 170750264

Following gene: 170750261

Centisome position: 67.7

GC content: 75.54

Gene sequence:

>1149_bases
ATGATTGACGCCACGGTGCCGGCCCTGTCCCTCGGCGCGCTCCTGGCCCTCGTCCAGGTCGGCAGCATCGCCGTCGCGGC
CCGGCGCCTCGGCCGGAACCACGGCCCGTCGCAATTCCCCGACGGCGCGCCCGTCTCCCTGGTCCGGCCGCTGCGCGGGG
TCGAGGCGTACAGCGAGGAGATGCTCGTCCGCAGCTTCCGCCTCGACTACCCGGCCTACGAGCTGATCTTCTGCGTGGCC
GACCCGGCCGACCCGATCGTGCCGATGGTGGAGCGCCTGATCGAGGCCCACCCGCAGGTGCCGGCCCGCCTGATCCGCGG
CGACGAGCGCGTCAGCGCGAACCCGAAGCTCAACAACTGCCTGCGCGGCTGGCGCGCCGCCGCCCACGACTGGGTGGTGC
TCGCCGATTCCAACGTGGCCATGCCGCCGGACTACCTCCAGCGGCTCCAGGCGGCGTGGCGCGACGATACCGGCCTCGTC
TGCTCCACCCCGGCCGGCGCCCGCCCGGGCAGCTTCATGGCGGAGGTGGAGTGCGCCTTCCTGAACACCCTCCAGGCGCG
CTGGCAATACGCCGCCGAGGCCTTCGGCCTGGGCTTCGCGCAGGGCAAGAGCATGCTCTGGCACAAGCCCTTCCTGGAGG
CGCAGGGCGGGCTCCAGGCGCTCGCCGCCGAGATCGCGGAGGACGCGGCCGCCACCAAGCTCGTGCGCGCCGCCGGCAAG
CGCGTCCACCTCGTGGCGAGCCCGTTCGAGCAGCCGCTCGGCCCGCGCGGCTTCCGGGAGGTCTGGGCGCGGCAGCTGCG
CTGGGCGCGCCTGCGCCGCGTGACCTTCCCGCTGTTCTTCGCCCCCGAGATCGGCAGCGGCGTCCTGCTGCCGGCGCTCC
TCGTCGCCCTCTGGGCCGGCAGCCTCGCGGGCCTCGCCGGCGCTGCCGGCCTCGCCGCCCTGTGCTATGCCGCCGAGCAC
CGGCTCGCGGTCCGCGCGGGTTGGCACCGTTCGCCCCGCACGCTGGCGGCCTTCCTGGCGCGCGACGCCCTGATCCCGGC
GATCTGGCTCGGCGCCTGGATGCGGAGCGCCATCGTGTGGCGGGGCAACGCCATGGACGTGCGCCCCCGGCGGGCCGCCG
GCGCGCGCTCCTACGCGCCGACGGCCTGA

Upstream 100 bases:

>100_bases
GGTGACCGGGACCGGGAGCGCCGGGCGGCGCTGTCACACGCCTGACGCGGTCGAGCCGCTAGCGGACCGGACCGCTCGCC
CGATCGCACGAGGGATCCGC

Downstream 100 bases:

>100_bases
CCGCCCGGCGATCGGAGGCCCTGACGTGTCGCGCCGCTACGCCCTCTACTGGCTGCCCGCCCCGGGATCCCGCCTCGAAG
CCTTCGGGCGCGCGGTCCTC

Product: ceramide glucosyltransferase

Products: UDP; D-glucosyl-N-acylsphingosine

Alternate protein names: Cell Wall Biosynthesis Glycosyltransferase-Like Protein; Glycosyl Transferase Group 2 Family; Glycosyl Transferase Family Protein; UDP-GlucoseCeramide Glycosyltransferase; Glycosyl Transferase Protein; Glycosyl Tranferase Homolog; Glycosyltransferase; Glycosyl Transferase; Cell Wall Biosynthesis Glycosyltransferase; Glycosyl Transferase Group 2 Family Protein; Glucosyltransferase

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MIDATVPALSLGALLALVQVGSIAVAARRLGRNHGPSQFPDGAPVSLVRPLRGVEAYSEEMLVRSFRLDYPAYELIFCVA
DPADPIVPMVERLIEAHPQVPARLIRGDERVSANPKLNNCLRGWRAAAHDWVVLADSNVAMPPDYLQRLQAAWRDDTGLV
CSTPAGARPGSFMAEVECAFLNTLQARWQYAAEAFGLGFAQGKSMLWHKPFLEAQGGLQALAAEIAEDAAATKLVRAAGK
RVHLVASPFEQPLGPRGFREVWARQLRWARLRRVTFPLFFAPEIGSGVLLPALLVALWAGSLAGLAGAAGLAALCYAAEH
RLAVRAGWHRSPRTLAAFLARDALIPAIWLGAWMRSAIVWRGNAMDVRPRRAAGARSYAPTA

Sequences:

>Translated_382_residues
MIDATVPALSLGALLALVQVGSIAVAARRLGRNHGPSQFPDGAPVSLVRPLRGVEAYSEEMLVRSFRLDYPAYELIFCVA
DPADPIVPMVERLIEAHPQVPARLIRGDERVSANPKLNNCLRGWRAAAHDWVVLADSNVAMPPDYLQRLQAAWRDDTGLV
CSTPAGARPGSFMAEVECAFLNTLQARWQYAAEAFGLGFAQGKSMLWHKPFLEAQGGLQALAAEIAEDAAATKLVRAAGK
RVHLVASPFEQPLGPRGFREVWARQLRWARLRRVTFPLFFAPEIGSGVLLPALLVALWAGSLAGLAGAAGLAALCYAAEH
RLAVRAGWHRSPRTLAAFLARDALIPAIWLGAWMRSAIVWRGNAMDVRPRRAAGARSYAPTA
>Mature_382_residues
MIDATVPALSLGALLALVQVGSIAVAARRLGRNHGPSQFPDGAPVSLVRPLRGVEAYSEEMLVRSFRLDYPAYELIFCVA
DPADPIVPMVERLIEAHPQVPARLIRGDERVSANPKLNNCLRGWRAAAHDWVVLADSNVAMPPDYLQRLQAAWRDDTGLV
CSTPAGARPGSFMAEVECAFLNTLQARWQYAAEAFGLGFAQGKSMLWHKPFLEAQGGLQALAAEIAEDAAATKLVRAAGK
RVHLVASPFEQPLGPRGFREVWARQLRWARLRRVTFPLFFAPEIGSGVLLPALLVALWAGSLAGLAGAAGLAALCYAAEH
RLAVRAGWHRSPRTLAAFLARDALIPAIWLGAWMRSAIVWRGNAMDVRPRRAAGARSYAPTA

Specific function: Unknown

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4507811, Length=295, Percent_Identity=30.8474576271186, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25147526, Length=365, Percent_Identity=23.2876712328767, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32566973, Length=364, Percent_Identity=24.1758241758242, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25149574, Length=362, Percent_Identity=23.7569060773481, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25149577, Length=362, Percent_Identity=23.7569060773481, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI32564728, Length=362, Percent_Identity=23.7569060773481, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25149580, Length=265, Percent_Identity=25.2830188679245, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24657569, Length=263, Percent_Identity=33.0798479087452, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.1.80

Molecular weight: Translated: 41381; Mature: 41381

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDATVPALSLGALLALVQVGSIAVAARRLGRNHGPSQFPDGAPVSLVRPLRGVEAYSEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MLVRSFRLDYPAYELIFCVADPADPIVPMVERLIEAHPQVPARLIRGDERVSANPKLNNC
HHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHH
LRGWRAAAHDWVVLADSNVAMPPDYLQRLQAAWRDDTGLVCSTPAGARPGSFMAEVECAF
HHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHH
LNTLQARWQYAAEAFGLGFAQGKSMLWHKPFLEAQGGLQALAAEIAEDAAATKLVRAAGK
HHHHHHHHHHHHHHHCCCHHHCCCCHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
RVHLVASPFEQPLGPRGFREVWARQLRWARLRRVTFPLFFAPEIGSGVLLPALLVALWAG
EEEEEECCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHH
SLAGLAGAAGLAALCYAAEHRLAVRAGWHRSPRTLAAFLARDALIPAIWLGAWMRSAIVW
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
RGNAMDVRPRRAAGARSYAPTA
CCCCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure
MIDATVPALSLGALLALVQVGSIAVAARRLGRNHGPSQFPDGAPVSLVRPLRGVEAYSEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MLVRSFRLDYPAYELIFCVADPADPIVPMVERLIEAHPQVPARLIRGDERVSANPKLNNC
HHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHH
LRGWRAAAHDWVVLADSNVAMPPDYLQRLQAAWRDDTGLVCSTPAGARPGSFMAEVECAF
HHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHH
LNTLQARWQYAAEAFGLGFAQGKSMLWHKPFLEAQGGLQALAAEIAEDAAATKLVRAAGK
HHHHHHHHHHHHHHHCCCHHHCCCCHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
RVHLVASPFEQPLGPRGFREVWARQLRWARLRRVTFPLFFAPEIGSGVLLPALLVALWAG
EEEEEECCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHH
SLAGLAGAAGLAALCYAAEHRLAVRAGWHRSPRTLAAFLARDALIPAIWLGAWMRSAIVW
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
RGNAMDVRPRRAAGARSYAPTA
CCCCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-glucose; N-acylsphingosine

Specific reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA