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The map label for this gene is htxC [H]

Identifier: 170750257

GI number: 170750257

Start: 4108200

End: 4109066

Strand: Reverse

Name: htxC [H]

Synonym: Mrad2831_3859

Alternate gene names: 170750257

Gene position: 4109066-4108200 (Counterclockwise)

Preceding gene: 170750258

Following gene: 170750255

Centisome position: 67.61

GC content: 73.59

Gene sequence:

>867_bases
ATGAGCGCGCGTCCCGAGGCCCTGCGGGCGGCGGCCCGGGCCGACCTCGCCCGCCTGCGCGCGCGCTACCCCGCGCAGTT
CCGCACCGACTGGCCGGGGCGGGCGCGGCTCGCCGCCCTGCTCGTCGTCCTGGTGGGGCTCGCGGCGCTCGGCGCCTGGC
GCCTCGACTTCTCGGTGGCGCGGATCCTCCACGGTCTCGGGCGGCTCGGCACCTTCGCGGTGCTGATGCTGCCGCCGTCG
CCGGAGGGCCAGTTCTGGACCTTCCTGCACGCGCTGGGCGAGACCCTCGGCATCGCCTTCCTGGGCACGCTGACGGCGGC
GATCCTCGCCTTCCCGGTGGCGTTCCTGGCGGCGCGGAACGTCGTGCCCAACCCGTTCGCGCGGTTCGCGGTCCGCCGCG
GCCTCGACGTGATGCGCTCGGTCGACGTCCTGATCTGGGCGCTGATCTGGATCAACGTCGTCGGCCTCGGCCCGTTCGCG
GGGGCGCTCGCGATCGCGTGCTCGGATTTCGGGGCGCTCGGCAAGCTGTTCTCCGAGGCGATCGAGACCTGCGACCGACG
CGCCGGCGAGGGCGTCGTCGCCTCGGGCGGCTCGGCGCTCCACCGCATCCGCTTCGGGCTGATCCCCGGGGTGCTGCCGG
TGCTGGCGAGCCAGGTCCTGTACTTCTTCGAGTCGAACACCCGCTCGGCGACGATCATCGGCATCGTCGGCGCGGGCGGC
ATCGGCCAGTACCTCACCGAGCTGATCCGCGTGCTGGAGCTGCAGCAGGTCGCCTTCCTGGTGCTGATGATCCTCGTGAC
CGTGGCGGCGATCGACTGGATCTCGACCCGCCTGCGCCGGGCGATCATCGGGCCGGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
ACGTGAGCGCGATCCTCGTGCTGATCATCCTGACCGTGTTCTGCATCGACCTCGTCACCGAGCGGGTCCGCCACCGCCTG
ATCGGCGCGGAGCAGGCCCG

Downstream 100 bases:

>100_bases
AGGAGGCCGCGCAGCGGGCGGTCCGTCCCATCCACCCCCTCATCCTGAGGTGCGGCCTGAGGTGCGGCGCGGCCGCCTCG
AAGGAGGGCTCGAGCCACCG

Product: phosphonate ABC transporter inner membrane protein

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSARPEALRAAARADLARLRARYPAQFRTDWPGRARLAALLVVLVGLAALGAWRLDFSVARILHGLGRLGTFAVLMLPPS
PEGQFWTFLHALGETLGIAFLGTLTAAILAFPVAFLAARNVVPNPFARFAVRRGLDVMRSVDVLIWALIWINVVGLGPFA
GALAIACSDFGALGKLFSEAIETCDRRAGEGVVASGGSALHRIRFGLIPGVLPVLASQVLYFFESNTRSATIIGIVGAGG
IGQYLTELIRVLELQQVAFLVLMILVTVAAIDWISTRLRRAIIGPAAR

Sequences:

>Translated_288_residues
MSARPEALRAAARADLARLRARYPAQFRTDWPGRARLAALLVVLVGLAALGAWRLDFSVARILHGLGRLGTFAVLMLPPS
PEGQFWTFLHALGETLGIAFLGTLTAAILAFPVAFLAARNVVPNPFARFAVRRGLDVMRSVDVLIWALIWINVVGLGPFA
GALAIACSDFGALGKLFSEAIETCDRRAGEGVVASGGSALHRIRFGLIPGVLPVLASQVLYFFESNTRSATIIGIVGAGG
IGQYLTELIRVLELQQVAFLVLMILVTVAAIDWISTRLRRAIIGPAAR
>Mature_287_residues
SARPEALRAAARADLARLRARYPAQFRTDWPGRARLAALLVVLVGLAALGAWRLDFSVARILHGLGRLGTFAVLMLPPSP
EGQFWTFLHALGETLGIAFLGTLTAAILAFPVAFLAARNVVPNPFARFAVRRGLDVMRSVDVLIWALIWINVVGLGPFAG
ALAIACSDFGALGKLFSEAIETCDRRAGEGVVASGGSALHRIRFGLIPGVLPVLASQVLYFFESNTRSATIIGIVGAGGI
GQYLTELIRVLELQQVAFLVLMILVTVAAIDWISTRLRRAIIGPAAR

Specific function: Probably forms part of a binding-protein-dependent hypophosphite transporter [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005769 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30805; Mature: 30674

Theoretical pI: Translated: 11.76; Mature: 11.76

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARPEALRAAARADLARLRARYPAQFRTDWPGRARLAALLVVLVGLAALGAWRLDFSVA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILHGLGRLGTFAVLMLPPSPEGQFWTFLHALGETLGIAFLGTLTAAILAFPVAFLAARN
HHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VVPNPFARFAVRRGLDVMRSVDVLIWALIWINVVGLGPFAGALAIACSDFGALGKLFSEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IETCDRRAGEGVVASGGSALHRIRFGLIPGVLPVLASQVLYFFESNTRSATIIGIVGAGG
HHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
IGQYLTELIRVLELQQVAFLVLMILVTVAAIDWISTRLRRAIIGPAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SARPEALRAAARADLARLRARYPAQFRTDWPGRARLAALLVVLVGLAALGAWRLDFSVA
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILHGLGRLGTFAVLMLPPSPEGQFWTFLHALGETLGIAFLGTLTAAILAFPVAFLAARN
HHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VVPNPFARFAVRRGLDVMRSVDVLIWALIWINVVGLGPFAGALAIACSDFGALGKLFSEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IETCDRRAGEGVVASGGSALHRIRFGLIPGVLPVLASQVLYFFESNTRSATIIGIVGAGG
HHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
IGQYLTELIRVLELQQVAFLVLMILVTVAAIDWISTRLRRAIIGPAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]