Click here to switch to the map view.

The map label for this gene is mltC [C]

Identifier: 170750170

GI number: 170750170

Start: 4013282

End: 4014262

Strand: Direct

Name: mltC [C]

Synonym: Mrad2831_3772

Alternate gene names: 170750170

Gene position: 4013282-4014262 (Clockwise)

Preceding gene: 170750169

Following gene: 170750171

Centisome position: 66.03

GC content: 77.27

Gene sequence:

>981_bases
ATGCATCGCCTCATCCTGGCCGCCGTCCTCGCGGTCGCGCCCGCCGCCGCCTTCGGGCAGGGCGCGCGCGACAATATCGA
CGCGCTGATCGAGCAGCAGGCCAAGGCGAACGGCGTTCCGGCGAGCTTCGTGCACGCCGTGGTGAAGCGCGAGAGCAACT
ACAACCCGCGGGCCAAGGGCGGCAGCGCCCTCGGCCTCATGCAGATCAAGCACGCGACCGCGCGCAGCCTGGGCTACACC
GGCGACGCCGCCGGCCTGTACGATCCGGAGACCAACCTGCGCTACGGCGTGGCCTATCTGGCGGGCGCCTACCGCACGGC
CAAGGGCAACGTCAGCCAAGCCTACCAGTACTACAACCGCGGCTACTACTACGCCGCCAAGCGCCAGGGCATCTCCACCG
AAGTCGCCTCGGTGGTCGCGCCGGTGGCAGCGTCGGCCAGCGCCCTGGCGAGCCTGTTCGGCGGCGGCGTCGCCGACACC
CGGAACAACCCCGCTGCCGCCGCCCTGGCCTACGCACCCACCGCCGCCGCGGTGGCGGAGGTTCCGACCGAGACCGTCGA
GGTACCGCTGCCGCCGCGCCGGCCCGCCGCCCTGGCCGGCGCGGCGATCGAGCTCGCCAGCCTGTCCATCGACCCGGCCG
CCGCGGCTCCGGGCCCGGCCCCGGGCACCGCGCAGGCCGCCGCGGCGCCCGCCGTGGAGGTGCCGCTGCCGCCGCGCCGC
CCCGCGGCCCTGGGCAGCGCCGTCGCGGCGGCCGCGCCGGCGCAGATCGCGGAGCTCCGGCTCTCTCCGCAGCCCGAGGC
CACCCCCGCTGCGATGACCCCCGCGGCCGCTCCGGCGCCGACCACCGAGGCCGCGGTGGAGGCCGTCGAGGTGCCGCTGC
CGCCGCGCCGGCCGTCGCTCCAGATGCTCGCCGCCGCCACACCGCGGCGCGCGCCGGCCGCCGCGCCGGTGCAGGAGGCC
ACGGCCCTGCCGGTCGAGTAG

Upstream 100 bases:

>100_bases
TCGCCCCGGTCGCCCACAGGCTGCCGAACCGGGGCCGCTTTCCGGCCTCATTTCCCCGTGACCTAGCTTGACCACAGAAC
AAGCAGCACCAGGTCTCGGA

Downstream 100 bases:

>100_bases
CGCGCCCTTCCGAACCGGCCGCGCACCGGGAAACCGCCGGCCGGCCGGGCCCTCTGCCCACACAAGGATCATGCCCAAGG
CTTGACCATCGGGTCGATCC

Product: lytic transglycosylase

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: Transglycosylase; Transglycosylase Protein; Lytic Murein Transglycosylase; Soluble Lytic Transglycosylase; Soluble Lytic Murein Transglycosylase; Transmembrane Protein; Transglycosylase Slt Family; Transglycosylase SLT Domain; Transglycosylase SLT Domain Protein

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MHRLILAAVLAVAPAAAFGQGARDNIDALIEQQAKANGVPASFVHAVVKRESNYNPRAKGGSALGLMQIKHATARSLGYT
GDAAGLYDPETNLRYGVAYLAGAYRTAKGNVSQAYQYYNRGYYYAAKRQGISTEVASVVAPVAASASALASLFGGGVADT
RNNPAAAALAYAPTAAAVAEVPTETVEVPLPPRRPAALAGAAIELASLSIDPAAAAPGPAPGTAQAAAAPAVEVPLPPRR
PAALGSAVAAAAPAQIAELRLSPQPEATPAAMTPAAAPAPTTEAAVEAVEVPLPPRRPSLQMLAAATPRRAPAAAPVQEA
TALPVE

Sequences:

>Translated_326_residues
MHRLILAAVLAVAPAAAFGQGARDNIDALIEQQAKANGVPASFVHAVVKRESNYNPRAKGGSALGLMQIKHATARSLGYT
GDAAGLYDPETNLRYGVAYLAGAYRTAKGNVSQAYQYYNRGYYYAAKRQGISTEVASVVAPVAASASALASLFGGGVADT
RNNPAAAALAYAPTAAAVAEVPTETVEVPLPPRRPAALAGAAIELASLSIDPAAAAPGPAPGTAQAAAAPAVEVPLPPRR
PAALGSAVAAAAPAQIAELRLSPQPEATPAAMTPAAAPAPTTEAAVEAVEVPLPPRRPSLQMLAAATPRRAPAAAPVQEA
TALPVE
>Mature_326_residues
MHRLILAAVLAVAPAAAFGQGARDNIDALIEQQAKANGVPASFVHAVVKRESNYNPRAKGGSALGLMQIKHATARSLGYT
GDAAGLYDPETNLRYGVAYLAGAYRTAKGNVSQAYQYYNRGYYYAAKRQGISTEVASVVAPVAASASALASLFGGGVADT
RNNPAAAALAYAPTAAAVAEVPTETVEVPLPPRRPAALAGAAIELASLSIDPAAAAPGPAPGTAQAAAAPAVEVPLPPRR
PAALGSAVAAAAPAQIAELRLSPQPEATPAAMTPAAAPAPTTEAAVEAVEVPLPPRRPSLQMLAAATPRRAPAAAPVQEA
TALPVE

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 32731; Mature: 32731

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRLILAAVLAVAPAAAFGQGARDNIDALIEQQAKANGVPASFVHAVVKRESNYNPRAKG
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
GSALGLMQIKHATARSLGYTGDAAGLYDPETNLRYGVAYLAGAYRTAKGNVSQAYQYYNR
CCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHC
GYYYAAKRQGISTEVASVVAPVAASASALASLFGGGVADTRNNPAAAALAYAPTAAAVAE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEECCCHHHHHHH
VPTETVEVPLPPRRPAALAGAAIELASLSIDPAAAAPGPAPGTAQAAAAPAVEVPLPPRR
CCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCEEECCCCCCC
PAALGSAVAAAAPAQIAELRLSPQPEATPAAMTPAAAPAPTTEAAVEAVEVPLPPRRPSL
CHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCH
QMLAAATPRRAPAAAPVQEATALPVE
HHHHHCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MHRLILAAVLAVAPAAAFGQGARDNIDALIEQQAKANGVPASFVHAVVKRESNYNPRAKG
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
GSALGLMQIKHATARSLGYTGDAAGLYDPETNLRYGVAYLAGAYRTAKGNVSQAYQYYNR
CCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHC
GYYYAAKRQGISTEVASVVAPVAASASALASLFGGGVADTRNNPAAAALAYAPTAAAVAE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEECCCHHHHHHH
VPTETVEVPLPPRRPAALAGAAIELASLSIDPAAAAPGPAPGTAQAAAAPAVEVPLPPRR
CCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCEEECCCCCCC
PAALGSAVAAAAPAQIAELRLSPQPEATPAAMTPAAAPAPTTEAAVEAVEVPLPPRRPSL
CHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCH
QMLAAATPRRAPAAAPVQEATALPVE
HHHHHCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA