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The map label for this gene is yajO [H]

Identifier: 170750129

GI number: 170750129

Start: 3972856

End: 3973866

Strand: Reverse

Name: yajO [H]

Synonym: Mrad2831_3731

Alternate gene names: 170750129

Gene position: 3973866-3972856 (Counterclockwise)

Preceding gene: 170750132

Following gene: 170750128

Centisome position: 65.38

GC content: 72.11

Gene sequence:

>1011_bases
ATGCAGTACCGCACGCTCGGCCGCTCCGGCCTCAAGGTCTCGCCGATCTGTCTCGGCACGATGATGTTCGGCGGCCCCAC
CGACGAGGCCACGGCCGGCCGCGTCGTCGCCAGCGCCCGGGAGGCCGGGATCAACTTCATCGACACGGCCAACGTCTACA
CGGAGGGCCGCTCGGAGGAGATCACCGGCCGGGCGATCAGGGCCGAGCGCGACGCCTGGGTCCTGGCCACCAAGGTCGCC
AACCCGACCGGGCCGGGCGTCAACGACCGCGGCCTCTCGCGGGTCCACGTGATGAAGGCCGCCGAGGACAGCCTGCGCCG
CCTCGGCACGGATGTCATCGACATCTACTACCTCCACAAGGAGGACCACGACACGCCGCTGGCCGAGACGGTCCGGGCGA
TCGCCGACCTCGTGCGGGCGGGCAAGATCCGCCATTTCGGCGTCTCGAATCACCGCTCCTGGCGGGTCGCCGAGATCTGC
CGGCTCTGCGACGAGGCCGGGATCGACCGGCCGGTGGTGAGCCAGCCGTACTACAACGCCTTCAACCGGATGCCCGAGAC
CGAGCACCTGCCGGCCTGCGCGCATTTCGGGCTCGGCGTCGTGCCGTACTCGCCGCTCGCCCGCGGCGTGCTCACCGGCA
AGTACGACCCCGACGCACCGCCGCCGGCCGAGTCGCGCGCCGGCCGCCAGGATGCCCGGATGATGCAGACCGAGTGGCGC
CCGGAATCCCTGCGCATCGCCCGGACCCTGAGGGAGCACGCCGAGGCCCGCGGCATCACGGCCGGCCAGTTCGCCACCGC
CTGGGTGCTGAACAACCGCCTCGTCACGGGCGTGATCGCCGGGCCGCGCACGGAGGCGCAGTGGCAGGAATATCTCGGCG
CCCTCGACTACGCCTTCACCCCGGAGGACGAGGCGCTGGTCGACGGGTTCGTGGCCGCGGGGCATCCGACGACGCCGGGC
TACAACGATCCGGCCTATCCGCTGGAGGGGCGGGTGCCGCGCAGCGGCTGA

Upstream 100 bases:

>100_bases
GCGGGCGTTCGCGGGTTACAGGGCGGCGTTGACCTGTGTTGTGGTTGACCGCGCCGTTCCCGCGGCGAGATAGCGGGACG
ACGGACGTTGGAGGGATCCC

Downstream 100 bases:

>100_bases
GCAAAGGCGATCTCCGACCGAACCCCTCATCCCGGGGTGCGAGCGCGGTGGGCCTCGAAGGAGGGCTCCTTCGAGGCCCC
CGCGACGCTCCGGCACCGCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MQYRTLGRSGLKVSPICLGTMMFGGPTDEATAGRVVASAREAGINFIDTANVYTEGRSEEITGRAIRAERDAWVLATKVA
NPTGPGVNDRGLSRVHVMKAAEDSLRRLGTDVIDIYYLHKEDHDTPLAETVRAIADLVRAGKIRHFGVSNHRSWRVAEIC
RLCDEAGIDRPVVSQPYYNAFNRMPETEHLPACAHFGLGVVPYSPLARGVLTGKYDPDAPPPAESRAGRQDARMMQTEWR
PESLRIARTLREHAEARGITAGQFATAWVLNNRLVTGVIAGPRTEAQWQEYLGALDYAFTPEDEALVDGFVAAGHPTTPG
YNDPAYPLEGRVPRSG

Sequences:

>Translated_336_residues
MQYRTLGRSGLKVSPICLGTMMFGGPTDEATAGRVVASAREAGINFIDTANVYTEGRSEEITGRAIRAERDAWVLATKVA
NPTGPGVNDRGLSRVHVMKAAEDSLRRLGTDVIDIYYLHKEDHDTPLAETVRAIADLVRAGKIRHFGVSNHRSWRVAEIC
RLCDEAGIDRPVVSQPYYNAFNRMPETEHLPACAHFGLGVVPYSPLARGVLTGKYDPDAPPPAESRAGRQDARMMQTEWR
PESLRIARTLREHAEARGITAGQFATAWVLNNRLVTGVIAGPRTEAQWQEYLGALDYAFTPEDEALVDGFVAAGHPTTPG
YNDPAYPLEGRVPRSG
>Mature_336_residues
MQYRTLGRSGLKVSPICLGTMMFGGPTDEATAGRVVASAREAGINFIDTANVYTEGRSEEITGRAIRAERDAWVLATKVA
NPTGPGVNDRGLSRVHVMKAAEDSLRRLGTDVIDIYYLHKEDHDTPLAETVRAIADLVRAGKIRHFGVSNHRSWRVAEIC
RLCDEAGIDRPVVSQPYYNAFNRMPETEHLPACAHFGLGVVPYSPLARGVLTGKYDPDAPPPAESRAGRQDARMMQTEWR
PESLRIARTLREHAEARGITAGQFATAWVLNNRLVTGVIAGPRTEAQWQEYLGALDYAFTPEDEALVDGFVAAGHPTTPG
YNDPAYPLEGRVPRSG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=304, Percent_Identity=33.8815789473684, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI27436964, Length=306, Percent_Identity=34.3137254901961, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI4504825, Length=302, Percent_Identity=33.7748344370861, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI27436962, Length=306, Percent_Identity=34.3137254901961, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI27436966, Length=306, Percent_Identity=33.9869281045752, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI27436971, Length=320, Percent_Identity=32.5, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI223718702, Length=311, Percent_Identity=34.4051446945338, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI41152114, Length=317, Percent_Identity=35.3312302839117, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI41327764, Length=313, Percent_Identity=35.4632587859425, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI223718708, Length=175, Percent_Identity=34.8571428571429, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI87081735, Length=315, Percent_Identity=38.4126984126984, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=33.1306990881459, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789199, Length=330, Percent_Identity=30.6060606060606, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1788070, Length=335, Percent_Identity=29.2537313432836, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788081, Length=314, Percent_Identity=29.2993630573248, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787674, Length=296, Percent_Identity=25.3378378378378, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI212645785, Length=299, Percent_Identity=24.4147157190635, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=325, Percent_Identity=28.9230769230769, Blast_Score=142, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6323998, Length=347, Percent_Identity=28.2420749279539, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=315, Percent_Identity=26.3492063492064, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319951, Length=222, Percent_Identity=29.7297297297297, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=274, Percent_Identity=26.2773722627737, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=33.974358974359, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640980, Length=317, Percent_Identity=27.7602523659306, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI45549126, Length=317, Percent_Identity=27.4447949526814, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24646155, Length=285, Percent_Identity=30.1754385964912, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24646159, Length=285, Percent_Identity=29.1228070175439, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36807; Mature: 36807

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYRTLGRSGLKVSPICLGTMMFGGPTDEATAGRVVASAREAGINFIDTANVYTEGRSEE
CCCCCCCCCCCEECHHEEEHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCHHCCCCCCC
ITGRAIRAERDAWVLATKVANPTGPGVNDRGLSRVHVMKAAEDSLRRLGTDVIDIYYLHK
CCCHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEC
EDHDTPLAETVRAIADLVRAGKIRHFGVSNHRSWRVAEICRLCDEAGIDRPVVSQPYYNA
CCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHH
FNRMPETEHLPACAHFGLGVVPYSPLARGVLTGKYDPDAPPPAESRAGRQDARMMQTEWR
HHCCCCCCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCC
PESLRIARTLREHAEARGITAGQFATAWVLNNRLVTGVIAGPRTEAQWQEYLGALDYAFT
CHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCC
PEDEALVDGFVAAGHPTTPGYNDPAYPLEGRVPRSG
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQYRTLGRSGLKVSPICLGTMMFGGPTDEATAGRVVASAREAGINFIDTANVYTEGRSEE
CCCCCCCCCCCEECHHEEEHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCHHCCCCCCC
ITGRAIRAERDAWVLATKVANPTGPGVNDRGLSRVHVMKAAEDSLRRLGTDVIDIYYLHK
CCCHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEC
EDHDTPLAETVRAIADLVRAGKIRHFGVSNHRSWRVAEICRLCDEAGIDRPVVSQPYYNA
CCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHH
FNRMPETEHLPACAHFGLGVVPYSPLARGVLTGKYDPDAPPPAESRAGRQDARMMQTEWR
HHCCCCCCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCC
PESLRIARTLREHAEARGITAGQFATAWVLNNRLVTGVIAGPRTEAQWQEYLGALDYAFT
CHHHHHHHHHHHHHHHCCCCCCHHHEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCC
PEDEALVDGFVAAGHPTTPGYNDPAYPLEGRVPRSG
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]