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The map label for this gene is bioC [H]

Identifier: 170750092

GI number: 170750092

Start: 3932264

End: 3933211

Strand: Direct

Name: bioC [H]

Synonym: Mrad2831_3693

Alternate gene names: 170750092

Gene position: 3932264-3933211 (Clockwise)

Preceding gene: 170750087

Following gene: 170750093

Centisome position: 64.7

GC content: 76.16

Gene sequence:

>948_bases
ATGGCCTCGCAGCTCAGTTCCGGCGACCTCCTCGCCGATCGCCGCTACCGCTACGCCGAGGCCTGCCTCGCCGACGGCGA
CCACGCGGGCGCCGCCGACCTCGCCGAGCAGGCCCTGGAGCGCGCCCCGCGCTACTTGCCGGCCTGGCTCCTGCTGGGCC
GGGCGCGCGCGGGTCTGGCCGCCTCCGGAACCGATCCGGCCCTGCGCGACGCGGCGGCGCAGGCCTACGCCCGCGCCCTC
GACATCGATCCCGAGGACCGGCTGGGCGTGCGCGCGCATCTCGTCCGCCTGGGCGGCGGCGACACCCTCCCGGTCCTGTC
GCCGGCCTATGTCCGCGCCCTGTTCGACGACTACGCGCCGCGCTTCGAGCGCCACCTCGTGGAGGGCCTCGGCTATGTCG
GCCCGCAACTCGTCCGCGACGCCCTGCCGCGCGCTCCGGAGCGCTTCGCGGTCGCCCTCGATCTCGGCTGCGGCACGGGG
CTGATGGGCGAGGTCGTGCGCGACCGGGTCGATCATCTCACCGGGATCGACCTCTCCCCCGGGATGCTGGCGCTGGCGCG
GACCAAGACGGCGCGGGGTCGGCCGCTCTACGAGCGCCTCGTCGAGGGCGACGTCGCCGCCGCCCTGGCCGACCTGCCGG
AGGCCTCGGCCGACCTCTGCCTCGCCGCGGACGTCCTGATCTACGTCGCGGACCTGGCGTCGTTCCTGGCGGGCGTGGGG
CGGGTCCTGCGGCCCGGCGGCCTCGGTGCCTTCACGGTGCAATCCCACGACGGCCCCGGCTCCGTCCTGGGCGAGGACGG
CCGCTACGCCCACGCGGATGCCCATCTCGCGGCGACGGCCGCCGTGTCCGGCTTGGAACGGCTGGCGGCGAGGCCCGCGG
AAGTCCGGCGGGAGGGAGGACGGCCGGTACCGGGGCGCGTCGTTGTGTTGCGGCGCACATCGGCATGA

Upstream 100 bases:

>100_bases
AGGGTGAGGAGATCGCTGGCGCGTATCGGCATCGGGTCCGTGCTGCCGGTGGAGTCCGCCGGTGGCCCCGGTATATAGGC
GCCCCCGAACCGGCAGACGC

Downstream 100 bases:

>100_bases
AACCGCTCCGCTATTCGTCCATTGTCAGTCGACCGCGACTGGGCGCGGCGGCTCGATCGGGGGATCAGCATGGCGGAATA
CGGAAGTCGGACAGGCGGTG

Product: type 11 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MASQLSSGDLLADRRYRYAEACLADGDHAGAADLAEQALERAPRYLPAWLLLGRARAGLAASGTDPALRDAAAQAYARAL
DIDPEDRLGVRAHLVRLGGGDTLPVLSPAYVRALFDDYAPRFERHLVEGLGYVGPQLVRDALPRAPERFAVALDLGCGTG
LMGEVVRDRVDHLTGIDLSPGMLALARTKTARGRPLYERLVEGDVAAALADLPEASADLCLAADVLIYVADLASFLAGVG
RVLRPGGLGAFTVQSHDGPGSVLGEDGRYAHADAHLAATAAVSGLERLAARPAEVRREGGRPVPGRVVVLRRTSA

Sequences:

>Translated_315_residues
MASQLSSGDLLADRRYRYAEACLADGDHAGAADLAEQALERAPRYLPAWLLLGRARAGLAASGTDPALRDAAAQAYARAL
DIDPEDRLGVRAHLVRLGGGDTLPVLSPAYVRALFDDYAPRFERHLVEGLGYVGPQLVRDALPRAPERFAVALDLGCGTG
LMGEVVRDRVDHLTGIDLSPGMLALARTKTARGRPLYERLVEGDVAAALADLPEASADLCLAADVLIYVADLASFLAGVG
RVLRPGGLGAFTVQSHDGPGSVLGEDGRYAHADAHLAATAAVSGLERLAARPAEVRREGGRPVPGRVVVLRRTSA
>Mature_314_residues
ASQLSSGDLLADRRYRYAEACLADGDHAGAADLAEQALERAPRYLPAWLLLGRARAGLAASGTDPALRDAAAQAYARALD
IDPEDRLGVRAHLVRLGGGDTLPVLSPAYVRALFDDYAPRFERHLVEGLGYVGPQLVRDALPRAPERFAVALDLGCGTGL
MGEVVRDRVDHLTGIDLSPGMLALARTKTARGRPLYERLVEGDVAAALADLPEASADLCLAADVLIYVADLASFLAGVGR
VLRPGGLGAFTVQSHDGPGSVLGEDGRYAHADAHLAATAAVSGLERLAARPAEVRREGGRPVPGRVVVLRRTSA

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG4976

COG function: function code R; Predicted methyltransferase (contains TPR repeat)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 33117; Mature: 32986

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQLSSGDLLADRRYRYAEACLADGDHAGAADLAEQALERAPRYLPAWLLLGRARAGLA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
ASGTDPALRDAAAQAYARALDIDPEDRLGVRAHLVRLGGGDTLPVLSPAYVRALFDDYAP
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHH
RFERHLVEGLGYVGPQLVRDALPRAPERFAVALDLGCGTGLMGEVVRDRVDHLTGIDLSP
HHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
GMLALARTKTARGRPLYERLVEGDVAAALADLPEASADLCLAADVLIYVADLASFLAGVG
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RVLRPGGLGAFTVQSHDGPGSVLGEDGRYAHADAHLAATAAVSGLERLAARPAEVRREGG
HHHCCCCCCEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHHHCCC
RPVPGRVVVLRRTSA
CCCCCEEEEEEECCC
>Mature Secondary Structure 
ASQLSSGDLLADRRYRYAEACLADGDHAGAADLAEQALERAPRYLPAWLLLGRARAGLA
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
ASGTDPALRDAAAQAYARALDIDPEDRLGVRAHLVRLGGGDTLPVLSPAYVRALFDDYAP
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHH
RFERHLVEGLGYVGPQLVRDALPRAPERFAVALDLGCGTGLMGEVVRDRVDHLTGIDLSP
HHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
GMLALARTKTARGRPLYERLVEGDVAAALADLPEASADLCLAADVLIYVADLASFLAGVG
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RVLRPGGLGAFTVQSHDGPGSVLGEDGRYAHADAHLAATAAVSGLERLAARPAEVRREGG
HHHCCCCCCEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHHHCCC
RPVPGRVVVLRRTSA
CCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]