Click here to switch to the map view.

The map label for this gene is yjiA [H]

Identifier: 170750084

GI number: 170750084

Start: 3920532

End: 3921539

Strand: Reverse

Name: yjiA [H]

Synonym: Mrad2831_3685

Alternate gene names: 170750084

Gene position: 3921539-3920532 (Counterclockwise)

Preceding gene: 170750088

Following gene: 170750083

Centisome position: 64.52

GC content: 67.76

Gene sequence:

>1008_bases
ATGTCCGATACGAGCAACGCTTCCGTCCCGGCCGCTCCCGGTTCAGCCGCCGGCAAGATCCCGGTCACCGTGCTCACCGG
CTATCTCGGCGCGGGCAAGACCACGCTCCTCAACCGGATCCTCACCGAGAACCACGGCAAGCGCTACGCCGTGATCGTCA
ACGAGTTCGGCGAGATCGGCATCGACAACGACCTCGTCGTCGGCGCGGACGAGGAGGTGTTCGAGATGAACAACGGCTGC
GTCTGCTGCACGGTGCGCGGCGACCTGATCCGGATCATGGACGGGCTGGTCAAGCGCCGGGGCAAGTTCGACGCGATCAT
CGTCGAGACCACCGGGCTCGCCGACCCGGCCCCCGTGGCGCAGACCTTCTTCGTCGACCAGGATGTCGGCGAGGCCGCCC
GCCTCGACGCCGTGGTGACGGTGGCCGACGCCAAGTGGCTGTCTGACCGCCTGAAGGACGCGCCCGAGGCGAAGAACCAG
ATCGCCTTCGCGGACGTGATCCTGCTCAACAAGAGCGACCTCGTCTCCCCGGCCGACCTCGACCGCGTCGAGGCCGAGAT
CCGCACGATCAACCCGCTGGCCAAGCTCCACCGGACGCAGAACTGCGCGGTGCCCCTCGACGCCGTGCTCGAGCGCAACG
CCTTCGACCTCGACCGCATCCTCGACGTCGAGCCCGACTTCCTGGAGGCGGGTCACCACCACCACCACGATTCCGACATC
CGCTCGGTCTCGGCGAAGATCGAGGGCGCGGTCGACCCGGACAAGTTCATGCCGTGGATCTCGAACCTGACCCAGTCGCA
GGGGCCGGACATCCTGCGGTGCAAGGGGATCGTGGCCTTCCCGGACGAGCCGAAGCGCTTCGTCTTCCAGGGCGTGCACA
TGATCCTCGACGGCGACGTGCAGGGCGACTGGGGCAAGGACGAGGAGCGGGTCTCGCGGGTGGTGTTCATCGGCCGCAAC
CTCGATCCGGCGGCGATCAAGGAGGGCTTCGAGGCCTGCCGCGCCTGA

Upstream 100 bases:

>100_bases
CCGTGTGGCCCCGTCTTCCTTTGACGGGATTTGTTACAATATGACAACGCTCGCGGGTCCAGGCCCGCGCGATCCCGCAC
CTGCCACCGAAGAACCCGTC

Downstream 100 bases:

>100_bases
ACCGGCGGTGCGCCGCCGAGGGGCGCGGCGCGCCGGGAAGGCGATTCTCAACGTTTGGATGGCATCACCGACGGCGCGGG
CCAGCGTAACCGGCCCGCGG

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSDTSNASVPAAPGSAAGKIPVTVLTGYLGAGKTTLLNRILTENHGKRYAVIVNEFGEIGIDNDLVVGADEEVFEMNNGC
VCCTVRGDLIRIMDGLVKRRGKFDAIIVETTGLADPAPVAQTFFVDQDVGEAARLDAVVTVADAKWLSDRLKDAPEAKNQ
IAFADVILLNKSDLVSPADLDRVEAEIRTINPLAKLHRTQNCAVPLDAVLERNAFDLDRILDVEPDFLEAGHHHHHDSDI
RSVSAKIEGAVDPDKFMPWISNLTQSQGPDILRCKGIVAFPDEPKRFVFQGVHMILDGDVQGDWGKDEERVSRVVFIGRN
LDPAAIKEGFEACRA

Sequences:

>Translated_335_residues
MSDTSNASVPAAPGSAAGKIPVTVLTGYLGAGKTTLLNRILTENHGKRYAVIVNEFGEIGIDNDLVVGADEEVFEMNNGC
VCCTVRGDLIRIMDGLVKRRGKFDAIIVETTGLADPAPVAQTFFVDQDVGEAARLDAVVTVADAKWLSDRLKDAPEAKNQ
IAFADVILLNKSDLVSPADLDRVEAEIRTINPLAKLHRTQNCAVPLDAVLERNAFDLDRILDVEPDFLEAGHHHHHDSDI
RSVSAKIEGAVDPDKFMPWISNLTQSQGPDILRCKGIVAFPDEPKRFVFQGVHMILDGDVQGDWGKDEERVSRVVFIGRN
LDPAAIKEGFEACRA
>Mature_334_residues
SDTSNASVPAAPGSAAGKIPVTVLTGYLGAGKTTLLNRILTENHGKRYAVIVNEFGEIGIDNDLVVGADEEVFEMNNGCV
CCTVRGDLIRIMDGLVKRRGKFDAIIVETTGLADPAPVAQTFFVDQDVGEAARLDAVVTVADAKWLSDRLKDAPEAKNQI
AFADVILLNKSDLVSPADLDRVEAEIRTINPLAKLHRTQNCAVPLDAVLERNAFDLDRILDVEPDFLEAGHHHHHDSDIR
SVSAKIEGAVDPDKFMPWISNLTQSQGPDILRCKGIVAFPDEPKRFVFQGVHMILDGDVQGDWGKDEERVSRVVFIGRNL
DPAAIKEGFEACRA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=351, Percent_Identity=38.7464387464387, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI126722884, Length=351, Percent_Identity=38.4615384615385, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI148727351, Length=351, Percent_Identity=38.4615384615385, Blast_Score=235, Evalue=5e-62,
Organism=Homo sapiens, GI146231952, Length=351, Percent_Identity=38.1766381766382, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI223941779, Length=350, Percent_Identity=37.4285714285714, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI223941776, Length=338, Percent_Identity=38.1656804733728, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI119120938, Length=345, Percent_Identity=33.9130434782609, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI310124603, Length=226, Percent_Identity=30.0884955752212, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI310124599, Length=188, Percent_Identity=32.4468085106383, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI169184311, Length=167, Percent_Identity=29.940119760479, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI87082430, Length=322, Percent_Identity=33.8509316770186, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1788499, Length=166, Percent_Identity=33.7349397590361, Blast_Score=88, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6324356, Length=243, Percent_Identity=32.5102880658436, Blast_Score=138, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 36460; Mature: 36328

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTSNASVPAAPGSAAGKIPVTVLTGYLGAGKTTLLNRILTENHGKRYAVIVNEFGEIG
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC
IDNDLVVGADEEVFEMNNGCVCCTVRGDLIRIMDGLVKRRGKFDAIIVETTGLADPAPVA
CCCCEEECCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHH
QTFFVDQDVGEAARLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVILLNKSDLVSPADL
HEEEECCCCCCHHHHCEEEEEHHHHHHHHHHHCCCCHHCCEEEEEEEEECCCCCCCCCHH
DRVEAEIRTINPLAKLHRTQNCAVPLDAVLERNAFDLDRILDVEPDFLEAGHHHHHDSDI
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHCCCCHHHHCCCCCCCCHHH
RSVSAKIEGAVDPDKFMPWISNLTQSQGPDILRCKGIVAFPDEPKRFVFQGVHMILDGDV
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECEEEECCCCHHHHHHHCEEEEEECCC
QGDWGKDEERVSRVVFIGRNLDPAAIKEGFEACRA
CCCCCCCHHHEEEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SDTSNASVPAAPGSAAGKIPVTVLTGYLGAGKTTLLNRILTENHGKRYAVIVNEFGEIG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC
IDNDLVVGADEEVFEMNNGCVCCTVRGDLIRIMDGLVKRRGKFDAIIVETTGLADPAPVA
CCCCEEECCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHH
QTFFVDQDVGEAARLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVILLNKSDLVSPADL
HEEEECCCCCCHHHHCEEEEEHHHHHHHHHHHCCCCHHCCEEEEEEEEECCCCCCCCCHH
DRVEAEIRTINPLAKLHRTQNCAVPLDAVLERNAFDLDRILDVEPDFLEAGHHHHHDSDI
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHCCCCHHHHCCCCCCCCHHH
RSVSAKIEGAVDPDKFMPWISNLTQSQGPDILRCKGIVAFPDEPKRFVFQGVHMILDGDV
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECEEEECCCCHHHHHHHCEEEEEECCC
QGDWGKDEERVSRVVFIGRNLDPAAIKEGFEACRA
CCCCCCCHHHEEEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]