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The map label for this gene is ndh [H]

Identifier: 170750079

GI number: 170750079

Start: 3913701

End: 3915032

Strand: Direct

Name: ndh [H]

Synonym: Mrad2831_3680

Alternate gene names: 170750079

Gene position: 3913701-3915032 (Clockwise)

Preceding gene: 170750078

Following gene: 170750080

Centisome position: 64.39

GC content: 71.25

Gene sequence:

>1332_bases
ATGGCATCCGTCGAGAACGAGTCGGGCCTTCATCGCGTCGTGGTGGTCGGCGGCGGCGCCGCCGGACTGCAGCTGGTCAC
GAAGCTCGGCGACAAGCTCGGGCGCGGCAAGCGCGCGCACGTCACCCTCGTGGACCGCGCCCGGACGCATATCTGGAAGC
CGCTGCTCCACGAGGTGGCGGCCGGCAGCCTCGACGTCGGCCACCACGCGGTGGATTACCTGCACCACGCCCACACGCAC
GGCTTCCGCTACCGGATCGGGCGGATGACCGGGCTCGACCGGGAGGCGCGCACGATCCAGCTCGCCGCGAGCTACGACGC
GGAAGGGCGCGAGGTCACGCCCGAGCGCGCCGTCCCCTACGACACGCTGGTGATGGCGGTGGGCTCCACCACCAACGATT
TCGGCACGCCGGGCGTCGCCGAGCACGCCATCGCCCTCGACACACAGGACCAGGCGGTGCGCTTCCACCAGCGTCTGGTG
AACGCCTCTCTGCGGGCGCACACGCAGGCCGGCCCGGTCCGGCCCGGCCAGCTCCACGTCACGGTGATCGGCGCGGGCGC
GACCGGGACGGAGCTCGCCGCCGAGCTGCACCGGACCCTGCGCCACGTCGTCTCCACCGGGCTCGACAAGATCGACCCGG
GCAAGGACATCCGCATCACCCTGGTCGAGGCCGCCGACCGGATCCTGCCGGCGGTGCCGCAGCGCCTCTCGGCCGAGGTG
ATGCAGCTCCTCAACAAGATCGGCGTCGACGTGCGCGTGAAGGCGCGGGTCACCGAGGTGCGCGCTGACGGCGTGCAGCT
CGCCGACGGCACCTTCATCCCGTCCGAGCTGGTCGTCTGGGCGGCGGGCGTGAAGGCGCCGCCCTTCCTGCAGGGCATCG
GCGGCCTGGAGACGACGCGGACCAACCAGCTGGTGGTGACGCCGACGCTGCAGACGACCCGCGATCCAGACATCTTCGCC
ATCGGCGACTGCGCCTACCTGGTGGAGGCCGGATCCGACACGCCGGTGCCGCCGCGCGCGCAGGCGGCCCACCAGCAGGC
GAGCCACCTGATCGGCCAGATCCAGGCGAAGATCGACGGCAAGCCGCTGAAGCCGTTCCGGTACAAGGATTTCGGCTCGC
TGGTCTCCCTCGGCGAGTACTCGACCGTGGGCAGCCTGATGGGCTTCGTCCGCGGCAAGAACATGCTCATCGCCGGTCTG
TTCGCCCGGATGATGTACCGCTCGCTCTACAAGATGCACGAGCGGGCGCTGCACGGCACGGCCAAGACTGCCCTCGACAC
CCTGGCCCGCGCGCTCACCCGGCGCACCGAGCCGCGGGTGAAGCTGCACTGA

Upstream 100 bases:

>100_bases
CTCGTGACCGGGGGTCGCGGCCGGCGATGTGGTATTCGGCAACCCAGGCCGTGTAAGGAGGCCGGCGACTGATCCCGGTC
CGGGGGGAGAAAGAGTGTCG

Downstream 100 bases:

>100_bases
CCGTCGCCGTACGAACCGAGGACGGGCGCCCGGATCGACCGGGCGCGCCACAGGAAGGAAACACCATGATCCTGGTAAGC
GTGATGTACCCGGCCGGCCC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MASVENESGLHRVVVVGGGAAGLQLVTKLGDKLGRGKRAHVTLVDRARTHIWKPLLHEVAAGSLDVGHHAVDYLHHAHTH
GFRYRIGRMTGLDREARTIQLAASYDAEGREVTPERAVPYDTLVMAVGSTTNDFGTPGVAEHAIALDTQDQAVRFHQRLV
NASLRAHTQAGPVRPGQLHVTVIGAGATGTELAAELHRTLRHVVSTGLDKIDPGKDIRITLVEAADRILPAVPQRLSAEV
MQLLNKIGVDVRVKARVTEVRADGVQLADGTFIPSELVVWAAGVKAPPFLQGIGGLETTRTNQLVVTPTLQTTRDPDIFA
IGDCAYLVEAGSDTPVPPRAQAAHQQASHLIGQIQAKIDGKPLKPFRYKDFGSLVSLGEYSTVGSLMGFVRGKNMLIAGL
FARMMYRSLYKMHERALHGTAKTALDTLARALTRRTEPRVKLH

Sequences:

>Translated_443_residues
MASVENESGLHRVVVVGGGAAGLQLVTKLGDKLGRGKRAHVTLVDRARTHIWKPLLHEVAAGSLDVGHHAVDYLHHAHTH
GFRYRIGRMTGLDREARTIQLAASYDAEGREVTPERAVPYDTLVMAVGSTTNDFGTPGVAEHAIALDTQDQAVRFHQRLV
NASLRAHTQAGPVRPGQLHVTVIGAGATGTELAAELHRTLRHVVSTGLDKIDPGKDIRITLVEAADRILPAVPQRLSAEV
MQLLNKIGVDVRVKARVTEVRADGVQLADGTFIPSELVVWAAGVKAPPFLQGIGGLETTRTNQLVVTPTLQTTRDPDIFA
IGDCAYLVEAGSDTPVPPRAQAAHQQASHLIGQIQAKIDGKPLKPFRYKDFGSLVSLGEYSTVGSLMGFVRGKNMLIAGL
FARMMYRSLYKMHERALHGTAKTALDTLARALTRRTEPRVKLH
>Mature_442_residues
ASVENESGLHRVVVVGGGAAGLQLVTKLGDKLGRGKRAHVTLVDRARTHIWKPLLHEVAAGSLDVGHHAVDYLHHAHTHG
FRYRIGRMTGLDREARTIQLAASYDAEGREVTPERAVPYDTLVMAVGSTTNDFGTPGVAEHAIALDTQDQAVRFHQRLVN
ASLRAHTQAGPVRPGQLHVTVIGAGATGTELAAELHRTLRHVVSTGLDKIDPGKDIRITLVEAADRILPAVPQRLSAEVM
QLLNKIGVDVRVKARVTEVRADGVQLADGTFIPSELVVWAAGVKAPPFLQGIGGLETTRTNQLVVTPTLQTTRDPDIFAI
GDCAYLVEAGSDTPVPPRAQAAHQQASHLIGQIQAKIDGKPLKPFRYKDFGSLVSLGEYSTVGSLMGFVRGKNMLIAGLF
ARMMYRSLYKMHERALHGTAKTALDTLARALTRRTEPRVKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=436, Percent_Identity=52.7522935779816, Blast_Score=439, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6323515, Length=475, Percent_Identity=25.2631578947368, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323794, Length=449, Percent_Identity=26.7260579064588, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320118, Length=444, Percent_Identity=23.8738738738739, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47904; Mature: 47773

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVENESGLHRVVVVGGGAAGLQLVTKLGDKLGRGKRAHVTLVDRARTHIWKPLLHEVA
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHH
AGSLDVGHHAVDYLHHAHTHGFRYRIGRMTGLDREARTIQLAASYDAEGREVTPERAVPY
CCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCH
DTLVMAVGSTTNDFGTPGVAEHAIALDTQDQAVRFHQRLVNASLRAHTQAGPVRPGQLHV
HHEEEEECCCCCCCCCCCHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
TVIGAGATGTELAAELHRTLRHVVSTGLDKIDPGKDIRITLVEAADRILPAVPQRLSAEV
EEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
MQLLNKIGVDVRVKARVTEVRADGVQLADGTFIPSELVVWAAGVKAPPFLQGIGGLETTR
HHHHHHCCCCEEEEEEEEEHHCCCEEECCCCCCCHHHHEEECCCCCCHHHHHCCCCCCCC
TNQLVVTPTLQTTRDPDIFAIGDCAYLVEAGSDTPVPPRAQAAHQQASHLIGQIQAKIDG
CCEEEEEECCCCCCCCCEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
KPLKPFRYKDFGSLVSLGEYSTVGSLMGFVRGKNMLIAGLFARMMYRSLYKMHERALHGT
CCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
AKTALDTLARALTRRTEPRVKLH
HHHHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure 
ASVENESGLHRVVVVGGGAAGLQLVTKLGDKLGRGKRAHVTLVDRARTHIWKPLLHEVA
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHH
AGSLDVGHHAVDYLHHAHTHGFRYRIGRMTGLDREARTIQLAASYDAEGREVTPERAVPY
CCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCH
DTLVMAVGSTTNDFGTPGVAEHAIALDTQDQAVRFHQRLVNASLRAHTQAGPVRPGQLHV
HHEEEEECCCCCCCCCCCHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
TVIGAGATGTELAAELHRTLRHVVSTGLDKIDPGKDIRITLVEAADRILPAVPQRLSAEV
EEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
MQLLNKIGVDVRVKARVTEVRADGVQLADGTFIPSELVVWAAGVKAPPFLQGIGGLETTR
HHHHHHCCCCEEEEEEEEEHHCCCEEECCCCCCCHHHHEEECCCCCCHHHHHCCCCCCCC
TNQLVVTPTLQTTRDPDIFAIGDCAYLVEAGSDTPVPPRAQAAHQQASHLIGQIQAKIDG
CCEEEEEECCCCCCCCCEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
KPLKPFRYKDFGSLVSLGEYSTVGSLMGFVRGKNMLIAGLFARMMYRSLYKMHERALHGT
CCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
AKTALDTLARALTRRTEPRVKLH
HHHHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]