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The map label for this gene is ubiH [H]

Identifier: 170750028

GI number: 170750028

Start: 3854528

End: 3855793

Strand: Direct

Name: ubiH [H]

Synonym: Mrad2831_3629

Alternate gene names: 170750028

Gene position: 3854528-3855793 (Clockwise)

Preceding gene: 170750024

Following gene: 170750034

Centisome position: 63.42

GC content: 78.04

Gene sequence:

>1266_bases
ATGACGGCCGAGACGCCTCGCCCCGGCAGCCGCAGCCTCCTGATCGCCGGCGGCGGCCTGCCCAGCCTCGCCCTGGCGCT
CGCCCTGAAGCAGGCCCACGGGCCGGCCCTGGCCGTGACGGTGATCGACCCGGGCGCGGCCGACCCCGCCCGGCATCGCG
GCCGCGCCTACGCCCTGGCGGCGGGCGGGCGGCGGATGCTGGAGCGCCTCGGCCTGTGGGCCCGGGTCGCCGACGCGGCC
GAGCCGATCGCCGAGATGGTGATCAGCGACAGCCGCCTCGCCGACCCGGTGCGGCCGGCCTTCCTGACCTTCGGCCGCGA
GGCGGACGCCGAGCGCGACGACGGCGAGCCCTTCGCCCACATGATCGAGGCCGAGCCGCTCGCCGCGGCCCTGGCGGAGG
CCTGCCGGGCGGCGGGGGTGGCGATCGTCGCCGCCGGGGTGGTGCGCGCGCTGCCGGAGGGGGCCGCGATCCGCGCGGCG
CTCACCACCGGCGAGACCCTGCGGGGCGACCTGCTGGTGGCCGCCGACGGGGCACGGTCGCGGCTGCGCGAGGCCGCGCG
GATCGGCTGGGTCGGCTGGTCCTACCCGCAGGTCGGCATCGTGGCGACGATCGGCCACGCGCGGCCGCACGAAGGCCGCG
CCTTCGAGCACTTCCTGCCCGCGGGCCCGTTCGCGATCCTGCCGCTGCGGGACGGCGGTCCCCTGGGGCACCGCTCGTCC
ATCGTCTGGACCGAGCGGTCGGACGACGCCGAGGCCCTGCTCTCCGGCGAGCCCGACGAGGTGCTCGCCGAGATCGAGCG
CCGGTTCACCCTGGATCTCGGCACGCTCGCGCTGGAGCACGGCCCGAGCCGGCACCCCCTCGCCTTCGGCATCGCCCGGG
CCTTCCGCGCCGAGCGTCTCGCCCTGCTGGGCGACGCCGCCCACGTGATCCACCCGATCGCCGGCCAGGGCCTCAACCTC
GGGCTCGCGGATGCCGCGGCGCTGGCCGAGGCCGTGACCGGCGCGCTGCGCCTCGGCCTCGACCCCGGAAGCCCCGACGT
GCTGCGCGCCTACGAGCGCGCCCGGCGCTTCGACAGCTTCGCCATGGCGGCGGCGACCGACGGGCTGAACCGGCTGTTCT
CGAACGACGCCCTGCCGCTGCGGCTCGCCCGCGACCTCGGCCTCGGGATCGTCGACCGGCTGCCGGGGCTCAAGCGCTTC
TTCATCGGCGAGGCCGCGGCCGCGCGCGACTCGCGGCCCCGGCTGATGCGGGGCGAGGCGCTCTGA

Upstream 100 bases:

>100_bases
GACCCGCGGGGTTTCCGTTCGTTGCCCGCGTGCGACATAGGCTGTTCGGACGAACCAATCCACGCGTCCCGCGTGCGGCA
ACCCTAGGAGATCCGCCCCG

Downstream 100 bases:

>100_bases
GGCGCCCGCCAGCCGCCGGCCTCAGGCCCGTTTCGGCGCGGGGCCGCCCTCGGGCGCTCCGGGGCGGAGCGCGTCCGCGG
CCCGCCGCCCGAGCGCCCGC

Product: UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTAETPRPGSRSLLIAGGGLPSLALALALKQAHGPALAVTVIDPGAADPARHRGRAYALAAGGRRMLERLGLWARVADAA
EPIAEMVISDSRLADPVRPAFLTFGREADAERDDGEPFAHMIEAEPLAAALAEACRAAGVAIVAAGVVRALPEGAAIRAA
LTTGETLRGDLLVAADGARSRLREAARIGWVGWSYPQVGIVATIGHARPHEGRAFEHFLPAGPFAILPLRDGGPLGHRSS
IVWTERSDDAEALLSGEPDEVLAEIERRFTLDLGTLALEHGPSRHPLAFGIARAFRAERLALLGDAAHVIHPIAGQGLNL
GLADAAALAEAVTGALRLGLDPGSPDVLRAYERARRFDSFAMAAATDGLNRLFSNDALPLRLARDLGLGIVDRLPGLKRF
FIGEAAAARDSRPRLMRGEAL

Sequences:

>Translated_421_residues
MTAETPRPGSRSLLIAGGGLPSLALALALKQAHGPALAVTVIDPGAADPARHRGRAYALAAGGRRMLERLGLWARVADAA
EPIAEMVISDSRLADPVRPAFLTFGREADAERDDGEPFAHMIEAEPLAAALAEACRAAGVAIVAAGVVRALPEGAAIRAA
LTTGETLRGDLLVAADGARSRLREAARIGWVGWSYPQVGIVATIGHARPHEGRAFEHFLPAGPFAILPLRDGGPLGHRSS
IVWTERSDDAEALLSGEPDEVLAEIERRFTLDLGTLALEHGPSRHPLAFGIARAFRAERLALLGDAAHVIHPIAGQGLNL
GLADAAALAEAVTGALRLGLDPGSPDVLRAYERARRFDSFAMAAATDGLNRLFSNDALPLRLARDLGLGIVDRLPGLKRF
FIGEAAAARDSRPRLMRGEAL
>Mature_420_residues
TAETPRPGSRSLLIAGGGLPSLALALALKQAHGPALAVTVIDPGAADPARHRGRAYALAAGGRRMLERLGLWARVADAAE
PIAEMVISDSRLADPVRPAFLTFGREADAERDDGEPFAHMIEAEPLAAALAEACRAAGVAIVAAGVVRALPEGAAIRAAL
TTGETLRGDLLVAADGARSRLREAARIGWVGWSYPQVGIVATIGHARPHEGRAFEHFLPAGPFAILPLRDGGPLGHRSSI
VWTERSDDAEALLSGEPDEVLAEIERRFTLDLGTLALEHGPSRHPLAFGIARAFRAERLALLGDAAHVIHPIAGQGLNLG
LADAAALAEAVTGALRLGLDPGSPDVLRAYERARRFDSFAMAAATDGLNRLFSNDALPLRLARDLGLGIVDRLPGLKRFF
IGEAAAARDSRPRLMRGEAL

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=400, Percent_Identity=26.75, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI32967307, Length=341, Percent_Identity=29.0322580645161, Blast_Score=131, Evalue=9e-31,
Organism=Escherichia coli, GI1789274, Length=389, Percent_Identity=35.4755784061697, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1789273, Length=404, Percent_Identity=32.9207920792079, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786883, Length=394, Percent_Identity=33.502538071066, Blast_Score=139, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI25146631, Length=449, Percent_Identity=26.0579064587973, Blast_Score=135, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6321694, Length=293, Percent_Identity=27.9863481228669, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI19920760, Length=391, Percent_Identity=26.8542199488491, Blast_Score=124, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 44240; Mature: 44109

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAETPRPGSRSLLIAGGGLPSLALALALKQAHGPALAVTVIDPGAADPARHRGRAYALA
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCEEEEE
AGGRRMLERLGLWARVADAAEPIAEMVISDSRLADPVRPAFLTFGREADAERDDGEPFAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHH
MIEAEPLAAALAEACRAAGVAIVAAGVVRALPEGAAIRAALTTGETLRGDLLVAADGARS
HHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCHHH
RLREAARIGWVGWSYPQVGIVATIGHARPHEGRAFEHFLPAGPFAILPLRDGGPLGHRSS
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCC
IVWTERSDDAEALLSGEPDEVLAEIERRFTLDLGTLALEHGPSRHPLAFGIARAFRAERL
EEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ALLGDAAHVIHPIAGQGLNLGLADAAALAEAVTGALRLGLDPGSPDVLRAYERARRFDSF
HHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AMAAATDGLNRLFSNDALPLRLARDLGLGIVDRLPGLKRFFIGEAAAARDSRPRLMRGEA
HHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHCCCHHHHHHCCHHHCCCCCCCCCCCCC
L
C
>Mature Secondary Structure 
TAETPRPGSRSLLIAGGGLPSLALALALKQAHGPALAVTVIDPGAADPARHRGRAYALA
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCEEEEE
AGGRRMLERLGLWARVADAAEPIAEMVISDSRLADPVRPAFLTFGREADAERDDGEPFAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHH
MIEAEPLAAALAEACRAAGVAIVAAGVVRALPEGAAIRAALTTGETLRGDLLVAADGARS
HHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCHHH
RLREAARIGWVGWSYPQVGIVATIGHARPHEGRAFEHFLPAGPFAILPLRDGGPLGHRSS
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCC
IVWTERSDDAEALLSGEPDEVLAEIERRFTLDLGTLALEHGPSRHPLAFGIARAFRAERL
EEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ALLGDAAHVIHPIAGQGLNLGLADAAALAEAVTGALRLGLDPGSPDVLRAYERARRFDSF
HHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AMAAATDGLNRLFSNDALPLRLARDLGLGIVDRLPGLKRFFIGEAAAARDSRPRLMRGEA
HHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHCCCHHHHHHCCHHHCCCCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]