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The map label for this gene is tesB [H]

Identifier: 170750027

GI number: 170750027

Start: 3853528

End: 3854427

Strand: Reverse

Name: tesB [H]

Synonym: Mrad2831_3628

Alternate gene names: 170750027

Gene position: 3854427-3853528 (Counterclockwise)

Preceding gene: 170750029

Following gene: 170750026

Centisome position: 63.42

GC content: 73.22

Gene sequence:

>900_bases
ATGACCGACGCCAACACCGACGCGATGACGGACGCCGTCGCCGAGCTGATCGCCATCCTCGACCTGGAGCGCCTGGAGGT
CGACCTGTTCCGCGGCCAGAACCCCAAGACGGGCTGGCGGCGCGTCTTCGGCGGGCAGGTGGTGGCGCAGGCGCTGGTCG
CCGCGACCCGGACGGTGCCGGACGACCGCCCCGCCCACTCCCTCCACGCCTACTTCATGCTGCCCGGCGACCCGCGCACG
CCCATCGTCTACGAGGTCGAGCGGATCCGGGACGGGCGGAGCTTCACGACCCGGCGGGTCAAGGCGATCCAGCACGGGCG
CGCGATCTTCGCCACGACGGTCTCCTACCAGGTCGTCGAGGAGGGGCTGACGCACCAGCCGGCGATGCCGGCGGTGGCCG
GACCCGAGGGGCTCCTCGACGGCAAGGCCCTGGCGGCCGCCGGCGGCACCGGGATGCCGGAGGCGATCGCCGCCTATTTC
GGCCGCGAGCGGCCGATCGCGCTGCGGCCGGTCGATCTCAACCGCTACCTGCCCGCCAGCGCGGGCGGCCGGGCGCCCGA
TCCGATCTTCAATGTCTGGCTGCGCGCGGCCTCGGCGCTGCCGGACGATCCGGCGCTGCATCGGGCCGTACTGGCCTACG
CCTCCGACATGACCCTGCTCGACGTCTCGCTGATCCCGCACGCGCGCTCCGTGTTCGATCCGGCGATCCAGGCCGCGAGC
CTCGACCACGCCCTCTGGTTCCACCGACCGGTCAAGATCGACGACTGGCTGCTCTACGCGCAGGACAGCCCGGTCGCGGG
CGGCGCCCGCGGCTTCGCGCGCGGCCAGATCTTCGACCGCGCCGGCCACCTCGTGGCGTCGGTGGCCCAGGAGGGTCTGA
TCCGGCCGACGCGGGATTAA

Upstream 100 bases:

>100_bases
CGGGGCGGATCTCCTAGGGTTGCCGCACGCGGGACGCGTGGATTGGTTCGTCCGAACAGCCTATGTCGCACGCGGGCAAC
GAACGGAAACCCCGCGGGTC

Downstream 100 bases:

>100_bases
AGCGGGTTCCCGCGCGTGTGTTACCGGCGTGCCACAGCTCGGGCTGCACGGATTCGGGCAGTTTGCCTCGACTTTGTGCG
TGATCGCTCCGGAGCCTGCC

Product: acyl-CoA thioesterase II

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTDANTDAMTDAVAELIAILDLERLEVDLFRGQNPKTGWRRVFGGQVVAQALVAATRTVPDDRPAHSLHAYFMLPGDPRT
PIVYEVERIRDGRSFTTRRVKAIQHGRAIFATTVSYQVVEEGLTHQPAMPAVAGPEGLLDGKALAAAGGTGMPEAIAAYF
GRERPIALRPVDLNRYLPASAGGRAPDPIFNVWLRAASALPDDPALHRAVLAYASDMTLLDVSLIPHARSVFDPAIQAAS
LDHALWFHRPVKIDDWLLYAQDSPVAGGARGFARGQIFDRAGHLVASVAQEGLIRPTRD

Sequences:

>Translated_299_residues
MTDANTDAMTDAVAELIAILDLERLEVDLFRGQNPKTGWRRVFGGQVVAQALVAATRTVPDDRPAHSLHAYFMLPGDPRT
PIVYEVERIRDGRSFTTRRVKAIQHGRAIFATTVSYQVVEEGLTHQPAMPAVAGPEGLLDGKALAAAGGTGMPEAIAAYF
GRERPIALRPVDLNRYLPASAGGRAPDPIFNVWLRAASALPDDPALHRAVLAYASDMTLLDVSLIPHARSVFDPAIQAAS
LDHALWFHRPVKIDDWLLYAQDSPVAGGARGFARGQIFDRAGHLVASVAQEGLIRPTRD
>Mature_298_residues
TDANTDAMTDAVAELIAILDLERLEVDLFRGQNPKTGWRRVFGGQVVAQALVAATRTVPDDRPAHSLHAYFMLPGDPRTP
IVYEVERIRDGRSFTTRRVKAIQHGRAIFATTVSYQVVEEGLTHQPAMPAVAGPEGLLDGKALAAAGGTGMPEAIAAYFG
RERPIALRPVDLNRYLPASAGGRAPDPIFNVWLRAASALPDDPALHRAVLAYASDMTLLDVSLIPHARSVFDPAIQAASL
DHALWFHRPVKIDDWLLYAQDSPVAGGARGFARGQIFDRAGHLVASVAQEGLIRPTRD

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=288, Percent_Identity=40.2777777777778, Blast_Score=203, Evalue=1e-52,
Organism=Escherichia coli, GI1786657, Length=287, Percent_Identity=45.2961672473868, Blast_Score=262, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71988741, Length=303, Percent_Identity=39.6039603960396, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17558508, Length=308, Percent_Identity=38.3116883116883, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI115532456, Length=275, Percent_Identity=37.4545454545455, Blast_Score=175, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17531889, Length=275, Percent_Identity=37.4545454545455, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17531885, Length=275, Percent_Identity=37.4545454545455, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71982224, Length=300, Percent_Identity=32.3333333333333, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI212645202, Length=264, Percent_Identity=33.7121212121212, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6322480, Length=310, Percent_Identity=26.7741935483871, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 32377; Mature: 32246

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDANTDAMTDAVAELIAILDLERLEVDLFRGQNPKTGWRRVFGGQVVAQALVAATRTVP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DDRPAHSLHAYFMLPGDPRTPIVYEVERIRDGRSFTTRRVKAIQHGRAIFATTVSYQVVE
CCCCCCCEEEEEEECCCCCCCEEEEHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHH
EGLTHQPAMPAVAGPEGLLDGKALAAAGGTGMPEAIAAYFGRERPIALRPVDLNRYLPAS
HCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCC
AGGRAPDPIFNVWLRAASALPDDPALHRAVLAYASDMTLLDVSLIPHARSVFDPAIQAAS
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHC
LDHALWFHRPVKIDDWLLYAQDSPVAGGARGFARGQIFDRAGHLVASVAQEGLIRPTRD
CCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDANTDAMTDAVAELIAILDLERLEVDLFRGQNPKTGWRRVFGGQVVAQALVAATRTVP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DDRPAHSLHAYFMLPGDPRTPIVYEVERIRDGRSFTTRRVKAIQHGRAIFATTVSYQVVE
CCCCCCCEEEEEEECCCCCCCEEEEHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHH
EGLTHQPAMPAVAGPEGLLDGKALAAAGGTGMPEAIAAYFGRERPIALRPVDLNRYLPAS
HCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCC
AGGRAPDPIFNVWLRAASALPDDPALHRAVLAYASDMTLLDVSLIPHARSVFDPAIQAAS
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHC
LDHALWFHRPVKIDDWLLYAQDSPVAGGARGFARGQIFDRAGHLVASVAQEGLIRPTRD
CCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]