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The map label for this gene is ffh [H]

Identifier: 170750017

GI number: 170750017

Start: 3843823

End: 3845388

Strand: Reverse

Name: ffh [H]

Synonym: Mrad2831_3618

Alternate gene names: 170750017

Gene position: 3845388-3843823 (Counterclockwise)

Preceding gene: 170750018

Following gene: 170750016

Centisome position: 63.27

GC content: 70.24

Gene sequence:

>1566_bases
ATGTTCGAAGGCCTGTCCGACCGCCTCTCCGGCATCCTCTCGGGACTCACCCGTCGCGGTGCCCTGACCGAGGCCGACGT
CACCGCCGCCATGCGCGAGGTGCGCCGCGCCCTGCTGGAGGCCGACGTCGCCCTCGAGGTGGTCCGCGGCTTCACCGACC
GGGTGAAGGAGAAGGCCGTCGGCGCCGTCGTGCTCAAGTCGGTGACGCCCGGCCAGATGGTCGTGAAGATCGTCAACGAC
GAGCTCGTGGCGATGCTCGGCACCGACGCCGAGACCGTCGATCTCAACGCCCCCGCCCCGGTGCCGATCCTGATGGTCGG
CCTGCAGGGCTCGGGCAAGACCACGACCACCGCCAAGATCGCCCGGCGCCTCTCCGACCGCGAGAAGCGCAAGGTGCTGC
TCGCCTCCCTCGACACGCGCCGCCCGGCCGCCATGGAGCAGCTCGCGGTGCTGGCCAAGCAGGTCGGCGTGGAGAGCCTG
CCGATCGTCGCCGGCCAGTCTGCGGTGCAGATCGCCAAGCGCGCCATGGACGCCGCCCGTCTCGGCGGGTTCGACGTGGT
GATGCTCGACACCGCCGGCCGCACCACGGTGGACGAGGGCCTGATGGCCGAGGCCGCCGAGGTGAAGGCCGCGACGAAGC
CCCACGAGGTGCTGCTCGTCGCCGACGCGCTCACCGGCCAGGACGCGGTCAACACCGCCCGCGCCTTCGACCAGCGCCTC
GGCGTCACCGGCATCGTCCTGACCCGGATGGACGGCGATTCCCGCGGCGGCGCGGCTCTGTCGATGCGCGCCGTCACCGG
CAAGCCGATCAAGCTCGTCGGCGTCGGCGAGAAGGTCGACGCGCTGGAGGAGTTCCACCCGGCCCGCGTCGCCAACCGCA
TCCTCGGCATGGGCGACATCGTCTCGCTCGTCGAGAAGGCCGCCGAGACCATCGACCACGAGCAGGCGCTCCGCACCGCG
GAGAAGATGCGCAAGGGCAAGTTCGATCTCGAAGACCTGTCCATGCAGCTCGCCCAGATGGAGAAGATGGGCGGCATCGG
CGGCCTGATGGGCATGCTGCCCGGGATGGGCCAGATCAAGAAGCAGGTCGAGGGCGCCAACCTCGACGAGAAGATATTCA
AGCGCCAGCGGGCGATCATCTCGTCGATGACCCCGCAGGAGCGGAAGAACCCCGACCTCCTCAAGAACAGCCGCAAGAAG
CGCATCGCGGCCGGCTCGGGGGTCGACGTCTCGGAGATCAACAAGCTCCTGAAGATGCACCGGACCATGGCCGACATGAT
GAAGGCGATGGGCCAGGGCAAGCGCGGGATCGGGCAGGCGCTCGGCTCGATGTTCGGCCTGGGCGGCGGCGGGATGGGCG
GTGGAATGCCCGGCCTCCCGCCCGGCATGCCGGAGCCGACGCCGGAGCAGATCGCGCAGCTCGAGAAGCAGTTCGGCGGC
AAGCTGCCGCCGATGCCGCCGGGCCTGGGCGGCGGGGGCGGGATGCCCAAGCTTCCGGGGCTTCCGGGCCTCGGCGGCCC
GAAACTTCCGGGTCTCGGTGGGTTCATGCCGGGGAAGAAGAAATGA

Upstream 100 bases:

>100_bases
GGACAAATTCGCGAGCGCCCTGCGCAGCTTCGAGGCCGCCCTCCAGGCGCGCCGCGTCGAGCGCGCCGGGCTCGAGCAGT
AACGGCGGGGCGTCAGGATC

Downstream 100 bases:

>100_bases
GCGTGCTCGCGGCCCAGGCCGTCGATCCCGAACTCGCGCGCCTGCGGGACAGCATCGACAATTTCGATGCGGCGCTGATC
CACCTCCTCGCCGAGCGTTT

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MFEGLSDRLSGILSGLTRRGALTEADVTAAMREVRRALLEADVALEVVRGFTDRVKEKAVGAVVLKSVTPGQMVVKIVND
ELVAMLGTDAETVDLNAPAPVPILMVGLQGSGKTTTTAKIARRLSDREKRKVLLASLDTRRPAAMEQLAVLAKQVGVESL
PIVAGQSAVQIAKRAMDAARLGGFDVVMLDTAGRTTVDEGLMAEAAEVKAATKPHEVLLVADALTGQDAVNTARAFDQRL
GVTGIVLTRMDGDSRGGAALSMRAVTGKPIKLVGVGEKVDALEEFHPARVANRILGMGDIVSLVEKAAETIDHEQALRTA
EKMRKGKFDLEDLSMQLAQMEKMGGIGGLMGMLPGMGQIKKQVEGANLDEKIFKRQRAIISSMTPQERKNPDLLKNSRKK
RIAAGSGVDVSEINKLLKMHRTMADMMKAMGQGKRGIGQALGSMFGLGGGGMGGGMPGLPPGMPEPTPEQIAQLEKQFGG
KLPPMPPGLGGGGGMPKLPGLPGLGGPKLPGLGGFMPGKKK

Sequences:

>Translated_521_residues
MFEGLSDRLSGILSGLTRRGALTEADVTAAMREVRRALLEADVALEVVRGFTDRVKEKAVGAVVLKSVTPGQMVVKIVND
ELVAMLGTDAETVDLNAPAPVPILMVGLQGSGKTTTTAKIARRLSDREKRKVLLASLDTRRPAAMEQLAVLAKQVGVESL
PIVAGQSAVQIAKRAMDAARLGGFDVVMLDTAGRTTVDEGLMAEAAEVKAATKPHEVLLVADALTGQDAVNTARAFDQRL
GVTGIVLTRMDGDSRGGAALSMRAVTGKPIKLVGVGEKVDALEEFHPARVANRILGMGDIVSLVEKAAETIDHEQALRTA
EKMRKGKFDLEDLSMQLAQMEKMGGIGGLMGMLPGMGQIKKQVEGANLDEKIFKRQRAIISSMTPQERKNPDLLKNSRKK
RIAAGSGVDVSEINKLLKMHRTMADMMKAMGQGKRGIGQALGSMFGLGGGGMGGGMPGLPPGMPEPTPEQIAQLEKQFGG
KLPPMPPGLGGGGGMPKLPGLPGLGGPKLPGLGGFMPGKKK
>Mature_521_residues
MFEGLSDRLSGILSGLTRRGALTEADVTAAMREVRRALLEADVALEVVRGFTDRVKEKAVGAVVLKSVTPGQMVVKIVND
ELVAMLGTDAETVDLNAPAPVPILMVGLQGSGKTTTTAKIARRLSDREKRKVLLASLDTRRPAAMEQLAVLAKQVGVESL
PIVAGQSAVQIAKRAMDAARLGGFDVVMLDTAGRTTVDEGLMAEAAEVKAATKPHEVLLVADALTGQDAVNTARAFDQRL
GVTGIVLTRMDGDSRGGAALSMRAVTGKPIKLVGVGEKVDALEEFHPARVANRILGMGDIVSLVEKAAETIDHEQALRTA
EKMRKGKFDLEDLSMQLAQMEKMGGIGGLMGMLPGMGQIKKQVEGANLDEKIFKRQRAIISSMTPQERKNPDLLKNSRKK
RIAAGSGVDVSEINKLLKMHRTMADMMKAMGQGKRGIGQALGSMFGLGGGGMGGGMPGLPPGMPEPTPEQIAQLEKQFGG
KLPPMPPGLGGGGGMPKLPGLPGLGGPKLPGLGGFMPGKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=514, Percent_Identity=30.5447470817121, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI226371618, Length=337, Percent_Identity=34.1246290801187, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI23308697, Length=312, Percent_Identity=30.1282051282051, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI295424842, Length=312, Percent_Identity=30.1282051282051, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=34.5911949685535, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=54.2452830188679, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1789874, Length=254, Percent_Identity=35.4330708661417, Blast_Score=135, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=502, Percent_Identity=28.8844621513944, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI193206261, Length=312, Percent_Identity=31.4102564102564, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=494, Percent_Identity=31.5789473684211, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6320498, Length=326, Percent_Identity=25.4601226993865, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI17647949, Length=509, Percent_Identity=29.0766208251473, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24641198, Length=324, Percent_Identity=29.320987654321, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 54716; Mature: 54716

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEGLSDRLSGILSGLTRRGALTEADVTAAMREVRRALLEADVALEVVRGFTDRVKEKAV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVVLKSVTPGQMVVKIVNDELVAMLGTDAETVDLNAPAPVPILMVGLQGSGKTTTTAKI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCCHHHHHH
ARRLSDREKRKVLLASLDTRRPAAMEQLAVLAKQVGVESLPIVAGQSAVQIAKRAMDAAR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LGGFDVVMLDTAGRTTVDEGLMAEAAEVKAATKPHEVLLVADALTGQDAVNTARAFDQRL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
GVTGIVLTRMDGDSRGGAALSMRAVTGKPIKLVGVGEKVDALEEFHPARVANRILGMGDI
CCCEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCHHHH
VSLVEKAAETIDHEQALRTAEKMRKGKFDLEDLSMQLAQMEKMGGIGGLMGMLPGMGQIK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHH
KQVEGANLDEKIFKRQRAIISSMTPQERKNPDLLKNSRKKRIAAGSGVDVSEINKLLKMH
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RTMADMMKAMGQGKRGIGQALGSMFGLGGGGMGGGMPGLPPGMPEPTPEQIAQLEKQFGG
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
KLPPMPPGLGGGGGMPKLPGLPGLGGPKLPGLGGFMPGKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFEGLSDRLSGILSGLTRRGALTEADVTAAMREVRRALLEADVALEVVRGFTDRVKEKAV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVVLKSVTPGQMVVKIVNDELVAMLGTDAETVDLNAPAPVPILMVGLQGSGKTTTTAKI
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCCHHHHHH
ARRLSDREKRKVLLASLDTRRPAAMEQLAVLAKQVGVESLPIVAGQSAVQIAKRAMDAAR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LGGFDVVMLDTAGRTTVDEGLMAEAAEVKAATKPHEVLLVADALTGQDAVNTARAFDQRL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
GVTGIVLTRMDGDSRGGAALSMRAVTGKPIKLVGVGEKVDALEEFHPARVANRILGMGDI
CCCEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCHHHH
VSLVEKAAETIDHEQALRTAEKMRKGKFDLEDLSMQLAQMEKMGGIGGLMGMLPGMGQIK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHH
KQVEGANLDEKIFKRQRAIISSMTPQERKNPDLLKNSRKKRIAAGSGVDVSEINKLLKMH
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RTMADMMKAMGQGKRGIGQALGSMFGLGGGGMGGGMPGLPPGMPEPTPEQIAQLEKQFGG
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
KLPPMPPGLGGGGGMPKLPGLPGLGGPKLPGLGGFMPGKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]