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The map label for this gene is 170750000

Identifier: 170750000

GI number: 170750000

Start: 3828770

End: 3829831

Strand: Direct

Name: 170750000

Synonym: Mrad2831_3601

Alternate gene names: NA

Gene position: 3828770-3829831 (Clockwise)

Preceding gene: 170749999

Following gene: 170750001

Centisome position: 63.0

GC content: 72.13

Gene sequence:

>1062_bases
ATGAAACGGCGCAGCCTGCTCACGGTCGCGAGTGCGGCCACGGTCATGACGCTCGGCGGCGTCGGCTACGCCGCGCACCG
GCGCGGACGGAATCCCTATTACCGCGGCCCGACCTCCGACCATTTCGACGGGCTGCGGTTCTTCCTGCCGGGACAGTCGA
CCGACAAGGCGCTGCCGGACGTGCTGCGCTGGCAGGCTAAGCGGCAGCGCGAGCCCTGGCCGAAGAGCTTCCCCAGCCCC
TATCCCGCCGACCGGCCACCGGAGCGGGTCGAAGGCCTGCGGGTCGTGCTGATCGGCCACGCGAGCTACCTCGTGCAGGT
CGCCGGCCGGAACATCCTGATCGATCCGGTCTTCGCCAAGCGCGCGAGCCCGGTCCGCTTCGCCGGGCCGAAGCGCGTCA
ACCCGCCGGGGATCGCCCTCGCCGACCTGCCGCCCATCGACGCGGTCCTCATCACCCACAATCACTACGACCATCTCGAC
GGGCCGAGCCTCGCCCGGATCTGGCAGGCGCACCAGCCGCTGATCGTGGCGCCCCTGGGCAACGACACGATCCTGCGCGG
CTACGACGACACGATGCATGTCGAGACCCGCGACTGGGGGGAGTCGGTCGATCTCGGCGACGGGCTGCAGGTCCACCTGA
CCCCCGCGAACCACTGGTCGGCCCGGGGCGTCAACGACCGACGGATGGCACTGTGGTGCGCCTTCGTGCTGACCTCGCCC
CGCGGCGTGCACTACCATGTCGGCGATACCGGCTTCGGCGACGGCGCGCTGTTCTCCGACGTCCGGGCCCGGTTCGGGCC
GCCGCGCCTCGCGACGCTGCCGATCGGCGCCTACGAGCCGCGCTGGTTCATGCAGGCCCAGCACGTCGATCCGGCCGAGG
CCGTGAAGGCCTTCACCCTGCTCGGCGCCGAGCAGGCCCTCGGCCACCATTGGGGCACGTTCCAGCTCACCGACGAAGGC
ATCGAGCGGCCCGTCGAGGCGCTCGCGGCGGCCCTCGGCGGCGCCGGTATCCCGGCCGAGCGCTTCGTCGCCCTCCGGCC
GGGCCAGGTCTGGGAGGCCTGA

Upstream 100 bases:

>100_bases
CCCGCGATGCGCCCCTGAGACCGCGCCGAATCCGCCCTGAGGCTCCCCGCCGCGCCGCGGCAGCGCTTGACCGCCCCCCG
GTTCCGGCCATCTCGGATCC

Downstream 100 bases:

>100_bases
CCCGCGCTGTCTCCGGGCTGTCTTCGGGCTGTCTCCGGGAAGCGGCGGCAGGCGCAGGCGGGCATTGGGCACGATGCGTG
CATCATTCTGTATGCAGCAT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKRRSLLTVASAATVMTLGGVGYAAHRRGRNPYYRGPTSDHFDGLRFFLPGQSTDKALPDVLRWQAKRQREPWPKSFPSP
YPADRPPERVEGLRVVLIGHASYLVQVAGRNILIDPVFAKRASPVRFAGPKRVNPPGIALADLPPIDAVLITHNHYDHLD
GPSLARIWQAHQPLIVAPLGNDTILRGYDDTMHVETRDWGESVDLGDGLQVHLTPANHWSARGVNDRRMALWCAFVLTSP
RGVHYHVGDTGFGDGALFSDVRARFGPPRLATLPIGAYEPRWFMQAQHVDPAEAVKAFTLLGAEQALGHHWGTFQLTDEG
IERPVEALAAALGGAGIPAERFVALRPGQVWEA

Sequences:

>Translated_353_residues
MKRRSLLTVASAATVMTLGGVGYAAHRRGRNPYYRGPTSDHFDGLRFFLPGQSTDKALPDVLRWQAKRQREPWPKSFPSP
YPADRPPERVEGLRVVLIGHASYLVQVAGRNILIDPVFAKRASPVRFAGPKRVNPPGIALADLPPIDAVLITHNHYDHLD
GPSLARIWQAHQPLIVAPLGNDTILRGYDDTMHVETRDWGESVDLGDGLQVHLTPANHWSARGVNDRRMALWCAFVLTSP
RGVHYHVGDTGFGDGALFSDVRARFGPPRLATLPIGAYEPRWFMQAQHVDPAEAVKAFTLLGAEQALGHHWGTFQLTDEG
IERPVEALAAALGGAGIPAERFVALRPGQVWEA
>Mature_353_residues
MKRRSLLTVASAATVMTLGGVGYAAHRRGRNPYYRGPTSDHFDGLRFFLPGQSTDKALPDVLRWQAKRQREPWPKSFPSP
YPADRPPERVEGLRVVLIGHASYLVQVAGRNILIDPVFAKRASPVRFAGPKRVNPPGIALADLPPIDAVLITHNHYDHLD
GPSLARIWQAHQPLIVAPLGNDTILRGYDDTMHVETRDWGESVDLGDGLQVHLTPANHWSARGVNDRRMALWCAFVLTSP
RGVHYHVGDTGFGDGALFSDVRARFGPPRLATLPIGAYEPRWFMQAQHVDPAEAVKAFTLLGAEQALGHHWGTFQLTDEG
IERPVEALAAALGGAGIPAERFVALRPGQVWEA

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=309, Percent_Identity=37.5404530744337, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI170932481, Length=309, Percent_Identity=37.5404530744337, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17543102, Length=272, Percent_Identity=36.7647058823529, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17543100, Length=272, Percent_Identity=36.7647058823529, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI25148824, Length=272, Percent_Identity=36.7647058823529, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17543104, Length=272, Percent_Identity=37.5, Blast_Score=177, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6325154, Length=238, Percent_Identity=34.0336134453782, Blast_Score=135, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38822; Mature: 38822

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRSLLTVASAATVMTLGGVGYAAHRRGRNPYYRGPTSDHFDGLRFFLPGQSTDKALPD
CCCCCEEEHHHHHHEEEECCCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHH
VLRWQAKRQREPWPKSFPSPYPADRPPERVEGLRVVLIGHASYLVQVAGRNILIDPVFAK
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCEEEEEEECHHHEEEECCCEEEECCHHHC
RASPVRFAGPKRVNPPGIALADLPPIDAVLITHNHYDHLDGPSLARIWQAHQPLIVAPLG
CCCCEEECCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEECC
NDTILRGYDDTMHVETRDWGESVDLGDGLQVHLTPANHWSARGVNDRRMALWCAFVLTSP
CCCEEECCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHEEEEEEHHCCC
RGVHYHVGDTGFGDGALFSDVRARFGPPRLATLPIGAYEPRWFMQAQHVDPAEAVKAFTL
CCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHEEEECCCCHHHHHHHHHH
LGAEQALGHHWGTFQLTDEGIERPVEALAAALGGAGIPAERFVALRPGQVWEA
HCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCCCCC
>Mature Secondary Structure
MKRRSLLTVASAATVMTLGGVGYAAHRRGRNPYYRGPTSDHFDGLRFFLPGQSTDKALPD
CCCCCEEEHHHHHHEEEECCCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHH
VLRWQAKRQREPWPKSFPSPYPADRPPERVEGLRVVLIGHASYLVQVAGRNILIDPVFAK
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCEEEEEEECHHHEEEECCCEEEECCHHHC
RASPVRFAGPKRVNPPGIALADLPPIDAVLITHNHYDHLDGPSLARIWQAHQPLIVAPLG
CCCCEEECCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEECC
NDTILRGYDDTMHVETRDWGESVDLGDGLQVHLTPANHWSARGVNDRRMALWCAFVLTSP
CCCEEECCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHEEEEEEHHCCC
RGVHYHVGDTGFGDGALFSDVRARFGPPRLATLPIGAYEPRWFMQAQHVDPAEAVKAFTL
CCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHEEEECCCCHHHHHHHHHH
LGAEQALGHHWGTFQLTDEGIERPVEALAAALGGAGIPAERFVALRPGQVWEA
HCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]