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The map label for this gene is hmrR2 [H]

Identifier: 170749984

GI number: 170749984

Start: 3810265

End: 3810723

Strand: Reverse

Name: hmrR2 [H]

Synonym: Mrad2831_3585

Alternate gene names: 170749984

Gene position: 3810723-3810265 (Counterclockwise)

Preceding gene: 170749985

Following gene: 170749983

Centisome position: 62.7

GC content: 73.86

Gene sequence:

>459_bases
ATGAGCGCGGCGAACCTGACGATCGGCGAGGCGGCGCGCCGCACCGGCGTCTCGGCCAAGATGATCCGCTGGTACGAGGC
GACCGGCCTGCTTCCGCCGGCCGCCCGGTCCGAGGCCGGCTACCGCCATTACGGCGAGGCGGACCTGCACACGCTGCGCT
TCATCCGCCGCGCCCGCGACCTCGGCTTCAGCGTGGGCGCGATCGCGGATCTCCTGGCGCTCTGGCGCGACCGGGCCCGG
CCGAGCGCCGGGGTGAAGGCGATCGCGCAGGAGCAGATCGCCGATCTGCGCCGCCGCATCGCCGAGATGGAGGGGATGGC
CCGGACGCTGGAGCATCTGGCGGAGGCCTGCTGCGGCGACGCGCGTCCAGAATGTCCGATCCTCGATGATCTCGCGGCGC
CGGATCACGGGCCGACGCGGCAGCGGGCGATCCGCGCGCTCGCCAAGCGTGGCCGTTGA

Upstream 100 bases:

>100_bases
CGTTCTCGAGCGTGTTCGTCCTCGGCAACGCCCTGCGGCTGCGCCGGGCCGGCGGGCGGCCCGCGGCGGCCGCGACGCCG
GCCCTCGCCGCGAGGCCGGC

Downstream 100 bases:

>100_bases
CGGCGGCTCTGGCCCCGGCTTTGCTGGTCCGACCCACCCGCAAAGGCCACGAGAGCCCCGACCCGATGCCCGTCCTCGAA
CGGATCCACGCCTTCGCCGA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MSAANLTIGEAARRTGVSAKMIRWYEATGLLPPAARSEAGYRHYGEADLHTLRFIRRARDLGFSVGAIADLLALWRDRAR
PSAGVKAIAQEQIADLRRRIAEMEGMARTLEHLAEACCGDARPECPILDDLAAPDHGPTRQRAIRALAKRGR

Sequences:

>Translated_152_residues
MSAANLTIGEAARRTGVSAKMIRWYEATGLLPPAARSEAGYRHYGEADLHTLRFIRRARDLGFSVGAIADLLALWRDRAR
PSAGVKAIAQEQIADLRRRIAEMEGMARTLEHLAEACCGDARPECPILDDLAAPDHGPTRQRAIRALAKRGR
>Mature_151_residues
SAANLTIGEAARRTGVSAKMIRWYEATGLLPPAARSEAGYRHYGEADLHTLRFIRRARDLGFSVGAIADLLALWRDRARP
SAGVKAIAQEQIADLRRRIAEMEGMARTLEHLAEACCGDARPECPILDDLAAPDHGPTRQRAIRALAKRGR

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=131, Percent_Identity=39.6946564885496, Blast_Score=106, Evalue=6e-25,
Organism=Escherichia coli, GI1789687, Length=127, Percent_Identity=40.9448818897638, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16684; Mature: 16553

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAANLTIGEAARRTGVSAKMIRWYEATGLLPPAARSEAGYRHYGEADLHTLRFIRRARD
CCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LGFSVGAIADLLALWRDRARPSAGVKAIAQEQIADLRRRIAEMEGMARTLEHLAEACCGD
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ARPECPILDDLAAPDHGPTRQRAIRALAKRGR
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAANLTIGEAARRTGVSAKMIRWYEATGLLPPAARSEAGYRHYGEADLHTLRFIRRARD
CCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LGFSVGAIADLLALWRDRARPSAGVKAIAQEQIADLRRRIAEMEGMARTLEHLAEACCGD
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ARPECPILDDLAAPDHGPTRQRAIRALAKRGR
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]