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The map label for this gene is oxyR [H]

Identifier: 170749976

GI number: 170749976

Start: 3798382

End: 3799299

Strand: Reverse

Name: oxyR [H]

Synonym: Mrad2831_3577

Alternate gene names: 170749976

Gene position: 3799299-3798382 (Counterclockwise)

Preceding gene: 170749977

Following gene: 170749969

Centisome position: 62.51

GC content: 70.59

Gene sequence:

>918_bases
GTGATCGACAAGCTGGACTTCCTGCTCGCGCTCGCCCGCGAGCAGCATTTCGGGCACGCCGCCGAAGCCTGCGGCGTGAC
CCAGCAGACGCTCTCGGCCGGCGTGAAGCAGCTGGAGAACCGCTTCGGCGTGCAGCTCGTGCTGCGCGGCTCCCGCTTCC
AGGGCTTCACCCCCGAGGGCGAGCGGGTCCTGGAATGGGCGCGGCGCATCGTGGCCGACGCGCGGGCCATGCACGAGGAG
GTCACCGGCCTGCGCCGGGGCCTGACCGGCCACCTGCGCATCGCCGCCATCCCCACGGCGTTGCCGATGATCGTGAACCT
CACGACGCCCTACCGCGAGCGGCACCCGGACGTGCGGCTGACGGTCGAATCCGCCACCTCGGCCGACATTTTCTCGTTGA
TTGAGAACCTGGAGGCGGATGCGGGCCTGACCTACCTCGACAATGAGCCCCTCGGGCGGGTGATCTCCGTTCCCCTCTAC
CGGGAGCGCTACCGCCTCGTGACGGCGATCGGCGGCCCGTTCGACGATCGCGCCAACGTGACCTGGGCCGAGACCAGCCG
GCTGCCCCTCTGCCTGCTCACGCCGAACATGCAGAACCGGCGGATCATCGACCATCAGATCCGGGAGGCGGGTGCGGATC
CCGCCGCGACCCTCGAATCGAACTCGATGATCGTGCTGCTGACCCATGTGCGCACCCTGCGCTGGGCCTCGATCATGCCG
GAGATTCTGGTCGACGCCCTCGGCCCCATGGCGGGCGTGCGCAGCCTCCCGATCACCGCGCCGGACCTGGAGCACGCGAT
CGGCCTCGTCGCCCCGCGGCGCGAGCCGTCCACGCCGATGGTCACGGCCCTCGTCTCTATCGCGCGGTCCCTGGCGCGGA
CGCTCGATCCGGATCTGGCAGCGTCGGGGCCCGCGTGA

Upstream 100 bases:

>100_bases
AAGGCGTTCATCCTGTTCCGCTGAGCGGGCGCGCTCGGTTGTGGCGGGCACGGCGGGTCGCTAGGTTTCCGGCGCCTCGC
CGTGCCGGGATGCCGTCGTC

Downstream 100 bases:

>100_bases
GCGATCGGCTCCGCGCCCGGACCGGGGCGCGGCGTGCCGGGAGCAATCCGCGGGTCGCACGGAGCGCGTGCACCGGCAGC
GTCAGGAGGAGCCAGAGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MIDKLDFLLALAREQHFGHAAEACGVTQQTLSAGVKQLENRFGVQLVLRGSRFQGFTPEGERVLEWARRIVADARAMHEE
VTGLRRGLTGHLRIAAIPTALPMIVNLTTPYRERHPDVRLTVESATSADIFSLIENLEADAGLTYLDNEPLGRVISVPLY
RERYRLVTAIGGPFDDRANVTWAETSRLPLCLLTPNMQNRRIIDHQIREAGADPAATLESNSMIVLLTHVRTLRWASIMP
EILVDALGPMAGVRSLPITAPDLEHAIGLVAPRREPSTPMVTALVSIARSLARTLDPDLAASGPA

Sequences:

>Translated_305_residues
MIDKLDFLLALAREQHFGHAAEACGVTQQTLSAGVKQLENRFGVQLVLRGSRFQGFTPEGERVLEWARRIVADARAMHEE
VTGLRRGLTGHLRIAAIPTALPMIVNLTTPYRERHPDVRLTVESATSADIFSLIENLEADAGLTYLDNEPLGRVISVPLY
RERYRLVTAIGGPFDDRANVTWAETSRLPLCLLTPNMQNRRIIDHQIREAGADPAATLESNSMIVLLTHVRTLRWASIMP
EILVDALGPMAGVRSLPITAPDLEHAIGLVAPRREPSTPMVTALVSIARSLARTLDPDLAASGPA
>Mature_305_residues
MIDKLDFLLALAREQHFGHAAEACGVTQQTLSAGVKQLENRFGVQLVLRGSRFQGFTPEGERVLEWARRIVADARAMHEE
VTGLRRGLTGHLRIAAIPTALPMIVNLTTPYRERHPDVRLTVESATSADIFSLIENLEADAGLTYLDNEPLGRVISVPLY
RERYRLVTAIGGPFDDRANVTWAETSRLPLCLLTPNMQNRRIIDHQIREAGADPAATLESNSMIVLLTHVRTLRWASIMP
EILVDALGPMAGVRSLPITAPDLEHAIGLVAPRREPSTPMVTALVSIARSLARTLDPDLAASGPA

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=296, Percent_Identity=26.6891891891892, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI157672245, Length=290, Percent_Identity=27.2413793103448, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786401, Length=134, Percent_Identity=34.3283582089552, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI2367136, Length=147, Percent_Identity=30.6122448979592, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788296, Length=225, Percent_Identity=25.3333333333333, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787879, Length=284, Percent_Identity=27.8169014084507, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693105, Length=265, Percent_Identity=22.2641509433962, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33449; Mature: 33449

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKLDFLLALAREQHFGHAAEACGVTQQTLSAGVKQLENRFGVQLVLRGSRFQGFTPEG
CCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCH
ERVLEWARRIVADARAMHEEVTGLRRGLTGHLRIAAIPTALPMIVNLTTPYRERHPDVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHEECCCCHHHCCCCEEE
TVESATSADIFSLIENLEADAGLTYLDNEPLGRVISVPLYRERYRLVTAIGGPFDDRANV
EECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCE
TWAETSRLPLCLLTPNMQNRRIIDHQIREAGADPAATLESNSMIVLLTHVRTLRWASIMP
EEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEECCCCEEEEEHHHHHHHHHHHHH
EILVDALGPMAGVRSLPITAPDLEHAIGLVAPRREPSTPMVTALVSIARSLARTLDPDLA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
ASGPA
CCCCC
>Mature Secondary Structure
MIDKLDFLLALAREQHFGHAAEACGVTQQTLSAGVKQLENRFGVQLVLRGSRFQGFTPEG
CCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCH
ERVLEWARRIVADARAMHEEVTGLRRGLTGHLRIAAIPTALPMIVNLTTPYRERHPDVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHEECCCCHHHCCCCEEE
TVESATSADIFSLIENLEADAGLTYLDNEPLGRVISVPLYRERYRLVTAIGGPFDDRANV
EECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCE
TWAETSRLPLCLLTPNMQNRRIIDHQIREAGADPAATLESNSMIVLLTHVRTLRWASIMP
EEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEECCCCEEEEEHHHHHHHHHHHHH
EILVDALGPMAGVRSLPITAPDLEHAIGLVAPRREPSTPMVTALVSIARSLARTLDPDLA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
ASGPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]