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The map label for this gene is qor [H]

Identifier: 170749934

GI number: 170749934

Start: 3750305

End: 3751276

Strand: Reverse

Name: qor [H]

Synonym: Mrad2831_3534

Alternate gene names: 170749934

Gene position: 3751276-3750305 (Counterclockwise)

Preceding gene: 170749935

Following gene: 170749933

Centisome position: 61.72

GC content: 75.93

Gene sequence:

>972_bases
ATGCGGGCGCTGCTGTGCACGAGGCTCGACGGGCCGGAGCATCTGGAGATCGTCGAGCGCCCCGACCCGGTGCCGGGTCC
CGGGCAGGCGCTGGTGCGGATGCGGCTCGCGGCGCTGAACTTCTTCGACACGCTGATCACCGCCGGGCGCTACCAGGTGA
AGCCGGCCCTGCCGTTCTCGCCGGGCGGCGAGGGGGTCGGCGTGGTCGAGGCGCTGGGCGAGGGCGCCGCGGGCGTGTCC
GTGGGCGACCGGGTGATCGTCCATGCCGGGCACGGCTGCTGCGCGGAGCTGATCGCCCTCGACGCCGCCCGGCTCACCCC
GGTGCCGGACGCCGTGCCGGACGCGCAGGCGGCCGGACTCACCATCACCTACGGCACCTCGCTCCACGCCCTGGCGAACC
GCGCCCGCCTGCAGCCCGGCGAGTGGCTGGCGGTCCTCGGCGCGTCCGGGGGCGTCGGCCTCGCCGCCGTCGAGCTCGGC
CGGCTGATGGGCGCCCGGGTGATCGCCTGCGCCTCCTCGGAGGAGAAGCTCGCGGTCGCCCGCGCCCACGGCGCCGAGGC
GGGCGTGGTCTACGACCCCGCGACGCTCAAGGACGAGCTGCGCCGGATCTCGGGCGGCGGGATCGACGTGGTCTACGACG
CGGTCGGCGACGCCTACGCGGAGCCGGCCCTGCGGGCGCTCGGCTGGCGCGGACGCTTCCTCGTGATCGGCTTCGCCGCC
GGCGCCATCCCGCGGCTGCCGCTGAACCTGATGCTCCTCAAGGAACTCGACGTGCAGGGCGTCCACTGGGGCGCCTTCCT
GGATCGCGAGCCCGAGGCCCACCGGGCCGATCAGCGCCGCCTCCTCGGCTGGGTCGCCGAGGGCGAGCTCACCGCGCAGG
TCCACGGCGTCTACCCGCTGGCGGAGTACCCGGAGGCCTTCGGCCTCCTGACCCGCCGGGCGGCCGTGGGCAAGGTTCTC
CTGCGGCCCTGA

Upstream 100 bases:

>100_bases
GAGGTGCTGGGCGCCCGCATCCGCGAGATGATCGGAACGGCTTGACCGCGCGGCCGGTTCGGGCCTGATCGGCCGGGAAT
TGCCGGGGAGGAGAGACGCC

Downstream 100 bases:

>100_bases
TCGGGCCGCGGCCGCCCGCCTTCGACCGGGTCGGCACTCGACCCGCCGCACGGCCTCGGCGGGCGGCGAGTCATGCGTTC
CGCGCTGATCTGCGGCGCGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MRALLCTRLDGPEHLEIVERPDPVPGPGQALVRMRLAALNFFDTLITAGRYQVKPALPFSPGGEGVGVVEALGEGAAGVS
VGDRVIVHAGHGCCAELIALDAARLTPVPDAVPDAQAAGLTITYGTSLHALANRARLQPGEWLAVLGASGGVGLAAVELG
RLMGARVIACASSEEKLAVARAHGAEAGVVYDPATLKDELRRISGGGIDVVYDAVGDAYAEPALRALGWRGRFLVIGFAA
GAIPRLPLNLMLLKELDVQGVHWGAFLDREPEAHRADQRRLLGWVAEGELTAQVHGVYPLAEYPEAFGLLTRRAAVGKVL
LRP

Sequences:

>Translated_323_residues
MRALLCTRLDGPEHLEIVERPDPVPGPGQALVRMRLAALNFFDTLITAGRYQVKPALPFSPGGEGVGVVEALGEGAAGVS
VGDRVIVHAGHGCCAELIALDAARLTPVPDAVPDAQAAGLTITYGTSLHALANRARLQPGEWLAVLGASGGVGLAAVELG
RLMGARVIACASSEEKLAVARAHGAEAGVVYDPATLKDELRRISGGGIDVVYDAVGDAYAEPALRALGWRGRFLVIGFAA
GAIPRLPLNLMLLKELDVQGVHWGAFLDREPEAHRADQRRLLGWVAEGELTAQVHGVYPLAEYPEAFGLLTRRAAVGKVL
LRP
>Mature_323_residues
MRALLCTRLDGPEHLEIVERPDPVPGPGQALVRMRLAALNFFDTLITAGRYQVKPALPFSPGGEGVGVVEALGEGAAGVS
VGDRVIVHAGHGCCAELIALDAARLTPVPDAVPDAQAAGLTITYGTSLHALANRARLQPGEWLAVLGASGGVGLAAVELG
RLMGARVIACASSEEKLAVARAHGAEAGVVYDPATLKDELRRISGGGIDVVYDAVGDAYAEPALRALGWRGRFLVIGFAA
GAIPRLPLNLMLLKELDVQGVHWGAFLDREPEAHRADQRRLLGWVAEGELTAQVHGVYPLAEYPEAFGLLTRRAAVGKVL
LRP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=30.8681672025724, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=30.0911854103343, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=30.0911854103343, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI28557745, Length=311, Percent_Identity=32.1543408360129, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=27.1084337349398, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=27.1084337349398, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI194239676, Length=215, Percent_Identity=32.5581395348837, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI24308257, Length=341, Percent_Identity=25.5131964809384, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI41872631, Length=307, Percent_Identity=27.3615635179153, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI67078404, Length=293, Percent_Identity=26.962457337884, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI67078406, Length=289, Percent_Identity=26.643598615917, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1790485, Length=329, Percent_Identity=29.1793313069909, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI226510941, Length=341, Percent_Identity=26.3929618768328, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=303, Percent_Identity=28.7128712871287, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17536829, Length=274, Percent_Identity=25.5474452554745, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133901710, Length=283, Percent_Identity=25.4416961130742, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI133901712, Length=283, Percent_Identity=25.4416961130742, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=334, Percent_Identity=27.2455089820359, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6324486, Length=339, Percent_Identity=24.7787610619469, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=338, Percent_Identity=23.9644970414201, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=354, Percent_Identity=24.0112994350282, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=354, Percent_Identity=23.4463276836158, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221330659, Length=297, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19920632, Length=297, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45550423, Length=305, Percent_Identity=24.5901639344262, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24581345, Length=297, Percent_Identity=26.2626262626263, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33890; Mature: 33890

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALLCTRLDGPEHLEIVERPDPVPGPGQALVRMRLAALNFFDTLITAGRYQVKPALPFS
CCCEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
PGGEGVGVVEALGEGAAGVSVGDRVIVHAGHGCCAELIALDAARLTPVPDAVPDAQAAGL
CCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCE
TITYGTSLHALANRARLQPGEWLAVLGASGGVGLAAVELGRLMGARVIACASSEEKLAVA
EEEECCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEE
RAHGAEAGVVYDPATLKDELRRISGGGIDVVYDAVGDAYAEPALRALGWRGRFLVIGFAA
ECCCCCCCEEECCHHHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHCCCCCEEEEEEEC
GAIPRLPLNLMLLKELDVQGVHWGAFLDREPEAHRADQRRLLGWVAEGELTAQVHGVYPL
CCCCCCCHHEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHEEEECCEEEEEEEECCCH
AEYPEAFGLLTRRAAVGKVLLRP
HHCHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MRALLCTRLDGPEHLEIVERPDPVPGPGQALVRMRLAALNFFDTLITAGRYQVKPALPFS
CCCEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
PGGEGVGVVEALGEGAAGVSVGDRVIVHAGHGCCAELIALDAARLTPVPDAVPDAQAAGL
CCCCCCHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCE
TITYGTSLHALANRARLQPGEWLAVLGASGGVGLAAVELGRLMGARVIACASSEEKLAVA
EEEECCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEE
RAHGAEAGVVYDPATLKDELRRISGGGIDVVYDAVGDAYAEPALRALGWRGRFLVIGFAA
ECCCCCCCEEECCHHHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHCCCCCEEEEEEEC
GAIPRLPLNLMLLKELDVQGVHWGAFLDREPEAHRADQRRLLGWVAEGELTAQVHGVYPL
CCCCCCCHHEEEEECCCCCCEEECCCCCCCCCHHHHHHHHHHEEEECCEEEEEEEECCCH
AEYPEAFGLLTRRAAVGKVLLRP
HHCHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]