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The map label for this gene is oxaA

Identifier: 170749903

GI number: 170749903

Start: 3718247

End: 3720100

Strand: Reverse

Name: oxaA

Synonym: Mrad2831_3503

Alternate gene names: 170749903

Gene position: 3720100-3718247 (Counterclockwise)

Preceding gene: 170749904

Following gene: 170749902

Centisome position: 61.21

GC content: 66.18

Gene sequence:

>1854_bases
ATGGGCAATGACAAGACGAACATGTTCGTGGCCATCGGCCTGTCGCTGCTGGTGCTGCTCGGGTGGCAGTACTTCGTGGC
CGGCCCGCGCATGGAGCAGCAGCGCCAGATCGAGGCGCAGAACAAGGCCGCGCAGCAGCAGCCCCCGGGCGTGACCCCGG
ACGGCGTGCCCTCGCCGTCCCCGAAGGAGGGCGGCCCGGCCGCGCCCGCGCCCGGCACGCTGCCGACCGCCCAGGGCGGC
CCGGTCTCCCGCGAGGCGGCGCTGGCCCGCTCGCCGCGCGTGCGGATCGAGACCCCGGCGCTCTCGGGCTCGATCGCCCT
GAAGGGCGGCCGCGTCGACGACGTCTCGCTCAAGAACTACCACGAGACCATCGACCCCAAGAGCCCCGAGATCGTGCTGT
TCTCGCCGGCCGGGACCGAGACGCCCTACTACGCCGAGTTCGGCTGGGTCGGCGCCAATGCCGGTCCGCTGCCGACCAAC
GACACCCTGTGGACCAGCGACGGCAAGACGCTCTCGCCCGGCATGCCCGTGACCCTGACCTGGGACAACGGCGCCGGCCT
CGTCTTCAAGCGGATCATCGCGGTCGACGACAAGTACATGTTCACGATCCGCGACGAGGTCGAGAACAAGGGCTCGGGCG
CGATCACGCTGTACCCGTACAGCCTCGTCTCCCGCTGGGGTAAGCCGCACACCCAGGGCTACTACGTCCTGCACGAGGGC
ATGATCGGCTATCTGGGCAACGACGGCCTGCAGGAATTCACCTACGACAAGCTCGCCAAGGAGGGCGCCTACGGCGGTGC
CAACACCAAGGGCAAGGCCTGGACCGGCGTGACCGGCGGCTTCGTCGGCATCACCGACAAGTACTGGGCGGCGGCCGCGA
TCCCCGATCAGGACACGCCCTACACCGGCGCCTTCACCGACCGGACCGACGGTGCCACCAACGTCTACCAGGCGAGCGTG
CGCGGCGACGCCGTGAACCTCGCGGCGGGTGCCTCGGCCACCGCGACGCAGCGGCTGTTCGCGGGCGCCAAGGAAGTCAA
CGTCATCAACAACTACGAGAAGGATCTCGGCATCAAGCACTTCGATCTGATGATCGACTGGGGCTGGTTCTTCTTCATCA
CCAAGCCGATGTTCCGGGCGCTGGACTTCTTCTACCACCTGTTCGGCAACTTCGGCGTCTCGATCCTGGTGGTGACCTTC
TGCCTGAAGCTGCTGTTCCTGCCGATCGCGAACCGGTCCTACGTCTCCATGGCCAAGATGAAGGCCGTGCAGCCGGAGAT
GGCCGCCATTCGCGAGCGGTACAAGGACGACCGCATGAAGCAGCAGCAGGCCACGATGGAGCTGTACAAGAAGGAGAAGA
TCAACCCGGTCGCCGGCTGCTGGCCGGTGCTGATCCAGATCCCGGTCTTCTTCGCGCTCTACAAGGTCCTGTTCATCACC
ATCGAGATGCGCCACGCGCCGTTCTTCGGCTGGATCCGCGACCTCGCGGCGCCGGATCCGACGAGCATCGTGAACCTGTT
CGGCCTGCTGCCGTTCCCGGCGCCCGATTTCGTGCACCTGGGCGTCTGGCCGATCATCATGGGCATCACGATGTTCGTGC
AGATGAAGATGAATCCCGCTCCGCCGGACCCGGTCCAGGCGCAGATCTTCACCTTCATGCCGATCGTGTTCACCTTCATG
CTGGGCTCGTTCCCCGCTGGCCTCGTGATCTACTGGGCCTGGAACAACACCCTGTCGGTGATCCAGCAGTACGTCATCAT
GCGCCGCAACGGCGTGAAGGTGGAGTTGTGGGACAACCTGCGATCGACGTTCCGCCGCGGCAACGGCACCAAAGCGGCCG
CCACCAAGAGCTGA

Upstream 100 bases:

>100_bases
CAGGGGTGCGACAGAGATCCCCGAATCACAGGCGCGCGCAGGTCCTCCGGGGCCGGCGACGCTCCTGTTGCCACTCCGAA
CGCGTGCGGCGGTGTCCCTG

Downstream 100 bases:

>100_bases
CAGGCGACACGCCGTGACCGACACCAACGACGACGCGGCCGACCTCGCCGAGGCCGGCCGCCTTCTCTTCGCCGGCGCCG
CCGACTTCTACGCGGCCGCC

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MGNDKTNMFVAIGLSLLVLLGWQYFVAGPRMEQQRQIEAQNKAAQQQPPGVTPDGVPSPSPKEGGPAAPAPGTLPTAQGG
PVSREAALARSPRVRIETPALSGSIALKGGRVDDVSLKNYHETIDPKSPEIVLFSPAGTETPYYAEFGWVGANAGPLPTN
DTLWTSDGKTLSPGMPVTLTWDNGAGLVFKRIIAVDDKYMFTIRDEVENKGSGAITLYPYSLVSRWGKPHTQGYYVLHEG
MIGYLGNDGLQEFTYDKLAKEGAYGGANTKGKAWTGVTGGFVGITDKYWAAAAIPDQDTPYTGAFTDRTDGATNVYQASV
RGDAVNLAAGASATATQRLFAGAKEVNVINNYEKDLGIKHFDLMIDWGWFFFITKPMFRALDFFYHLFGNFGVSILVVTF
CLKLLFLPIANRSYVSMAKMKAVQPEMAAIRERYKDDRMKQQQATMELYKKEKINPVAGCWPVLIQIPVFFALYKVLFIT
IEMRHAPFFGWIRDLAAPDPTSIVNLFGLLPFPAPDFVHLGVWPIIMGITMFVQMKMNPAPPDPVQAQIFTFMPIVFTFM
LGSFPAGLVIYWAWNNTLSVIQQYVIMRRNGVKVELWDNLRSTFRRGNGTKAAATKS

Sequences:

>Translated_617_residues
MGNDKTNMFVAIGLSLLVLLGWQYFVAGPRMEQQRQIEAQNKAAQQQPPGVTPDGVPSPSPKEGGPAAPAPGTLPTAQGG
PVSREAALARSPRVRIETPALSGSIALKGGRVDDVSLKNYHETIDPKSPEIVLFSPAGTETPYYAEFGWVGANAGPLPTN
DTLWTSDGKTLSPGMPVTLTWDNGAGLVFKRIIAVDDKYMFTIRDEVENKGSGAITLYPYSLVSRWGKPHTQGYYVLHEG
MIGYLGNDGLQEFTYDKLAKEGAYGGANTKGKAWTGVTGGFVGITDKYWAAAAIPDQDTPYTGAFTDRTDGATNVYQASV
RGDAVNLAAGASATATQRLFAGAKEVNVINNYEKDLGIKHFDLMIDWGWFFFITKPMFRALDFFYHLFGNFGVSILVVTF
CLKLLFLPIANRSYVSMAKMKAVQPEMAAIRERYKDDRMKQQQATMELYKKEKINPVAGCWPVLIQIPVFFALYKVLFIT
IEMRHAPFFGWIRDLAAPDPTSIVNLFGLLPFPAPDFVHLGVWPIIMGITMFVQMKMNPAPPDPVQAQIFTFMPIVFTFM
LGSFPAGLVIYWAWNNTLSVIQQYVIMRRNGVKVELWDNLRSTFRRGNGTKAAATKS
>Mature_616_residues
GNDKTNMFVAIGLSLLVLLGWQYFVAGPRMEQQRQIEAQNKAAQQQPPGVTPDGVPSPSPKEGGPAAPAPGTLPTAQGGP
VSREAALARSPRVRIETPALSGSIALKGGRVDDVSLKNYHETIDPKSPEIVLFSPAGTETPYYAEFGWVGANAGPLPTND
TLWTSDGKTLSPGMPVTLTWDNGAGLVFKRIIAVDDKYMFTIRDEVENKGSGAITLYPYSLVSRWGKPHTQGYYVLHEGM
IGYLGNDGLQEFTYDKLAKEGAYGGANTKGKAWTGVTGGFVGITDKYWAAAAIPDQDTPYTGAFTDRTDGATNVYQASVR
GDAVNLAAGASATATQRLFAGAKEVNVINNYEKDLGIKHFDLMIDWGWFFFITKPMFRALDFFYHLFGNFGVSILVVTFC
LKLLFLPIANRSYVSMAKMKAVQPEMAAIRERYKDDRMKQQQATMELYKKEKINPVAGCWPVLIQIPVFFALYKVLFITI
EMRHAPFFGWIRDLAAPDPTSIVNLFGLLPFPAPDFVHLGVWPIIMGITMFVQMKMNPAPPDPVQAQIFTFMPIVFTFML
GSFPAGLVIYWAWNNTLSVIQQYVIMRRNGVKVELWDNLRSTFRRGNGTKAAATKS

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=539, Percent_Identity=29.6846011131725, Blast_Score=233, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_METRJ (B1LTW1)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001756163.1
- GeneID:   6139556
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_3503
- HOGENOM:   HBG507812
- OMA:   FVTIEMR
- ProtClustDB:   CLSK2331107
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 67990; Mature: 67859

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1a3e9a44)-; HASH(0x1b8e378c)-; HASH(0x1c0e729c)-; HASH(0x1baef7b0)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNDKTNMFVAIGLSLLVLLGWQYFVAGPRMEQQRQIEAQNKAAQQQPPGVTPDGVPSPS
CCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PKEGGPAAPAPGTLPTAQGGPVSREAALARSPRVRIETPALSGSIALKGGRVDDVSLKNY
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCCHHHH
HETIDPKSPEIVLFSPAGTETPYYAEFGWVGANAGPLPTNDTLWTSDGKTLSPGMPVTLT
HHHCCCCCCCEEEECCCCCCCCEEEECCEECCCCCCCCCCCCEECCCCCEECCCCCEEEE
WDNGAGLVFKRIIAVDDKYMFTIRDEVENKGSGAITLYPYSLVSRWGKPHTQGYYVLHEG
ECCCCCHHHHHHHHCCCCEEEEEEHHHCCCCCCEEEEEEHHHHHHCCCCCCCCEEEEECC
MIGYLGNDGLQEFTYDKLAKEGAYGGANTKGKAWTGVTGGFVGITDKYWAAAAIPDQDTP
CEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEECCCCCEEEEECCCCCCC
YTGAFTDRTDGATNVYQASVRGDAVNLAAGASATATQRLFAGAKEVNVINNYEKDLGIKH
CCCCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHCCCHHHHHHHCHHHHCCCEE
FDLMIDWGWFFFITKPMFRALDFFYHLFGNFGVSILVVTFCLKLLFLPIANRSYVSMAKM
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KAVQPEMAAIRERYKDDRMKQQQATMELYKKEKINPVAGCWPVLIQIPVFFALYKVLFIT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEE
IEMRHAPFFGWIRDLAAPDPTSIVNLFGLLPFPAPDFVHLGVWPIIMGITMFVQMKMNPA
EEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHEEEECCCC
PPDPVQAQIFTFMPIVFTFMLGSFPAGLVIYWAWNNTLSVIQQYVIMRRNGVKVELWDNL
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEHHHH
RSTFRRGNGTKAAATKS
HHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
GNDKTNMFVAIGLSLLVLLGWQYFVAGPRMEQQRQIEAQNKAAQQQPPGVTPDGVPSPS
CCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PKEGGPAAPAPGTLPTAQGGPVSREAALARSPRVRIETPALSGSIALKGGRVDDVSLKNY
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCCHHHH
HETIDPKSPEIVLFSPAGTETPYYAEFGWVGANAGPLPTNDTLWTSDGKTLSPGMPVTLT
HHHCCCCCCCEEEECCCCCCCCEEEECCEECCCCCCCCCCCCEECCCCCEECCCCCEEEE
WDNGAGLVFKRIIAVDDKYMFTIRDEVENKGSGAITLYPYSLVSRWGKPHTQGYYVLHEG
ECCCCCHHHHHHHHCCCCEEEEEEHHHCCCCCCEEEEEEHHHHHHCCCCCCCCEEEEECC
MIGYLGNDGLQEFTYDKLAKEGAYGGANTKGKAWTGVTGGFVGITDKYWAAAAIPDQDTP
CEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEECCCCCEEEEECCCCCCC
YTGAFTDRTDGATNVYQASVRGDAVNLAAGASATATQRLFAGAKEVNVINNYEKDLGIKH
CCCCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHCCCHHHHHHHCHHHHCCCEE
FDLMIDWGWFFFITKPMFRALDFFYHLFGNFGVSILVVTFCLKLLFLPIANRSYVSMAKM
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KAVQPEMAAIRERYKDDRMKQQQATMELYKKEKINPVAGCWPVLIQIPVFFALYKVLFIT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEE
IEMRHAPFFGWIRDLAAPDPTSIVNLFGLLPFPAPDFVHLGVWPIIMGITMFVQMKMNPA
EEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHEEEECCCC
PPDPVQAQIFTFMPIVFTFMLGSFPAGLVIYWAWNNTLSVIQQYVIMRRNGVKVELWDNL
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEHHHH
RSTFRRGNGTKAAATKS
HHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA