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The map label for this gene is qseD [H]

Identifier: 170749898

GI number: 170749898

Start: 3714208

End: 3715122

Strand: Reverse

Name: qseD [H]

Synonym: Mrad2831_3498

Alternate gene names: 170749898

Gene position: 3715122-3714208 (Counterclockwise)

Preceding gene: 170749901

Following gene: 170749895

Centisome position: 61.13

GC content: 75.3

Gene sequence:

>915_bases
ATGGATCTGGACTGGATGAGGGATTTCCTCGCGCTCGCCGAGCACCGGACCTTCTCGCGGGCCGCCGAGGCCCGGAACGT
GACGCAGCCGGCCTTCAGCCGACGGATCCGCGCGCTGGAGGAGTGGGTTGGGACGCCGCTGTTCCTGCGGAGCGCGCGAG
GGGCAGGCCTGACCGCCGCGGGAGCGCGCTTCCGGCCGGGCGCCGAGGAGCTGCTGCGGGGCCTGGATCGGGCGCGCGGC
GAGGCCCGGGCCGCCGGTGCGCGCGCGGACGCGAGCCTCGCGATCGCGGCGACGCACGCGCTGTCGTTCACGTTCTTCCC
AAGTTGGATCCGGCAGCACGCGCCCTTCGAGACGCTCGGCGCCCTCAACCTGATCTCGGACAGCATGGCGGCCTGCGAGG
CCATCCTGCTGGCCGGCGAGGTGCAGCTGCTCCTGTGCCACCATCGCGCGGACCTGCCCACGCGCCTGGACGATGGCCGC
TGCGAGTCCATCCGCGTCGGCGCGGACAGCCTGGTGCCGCTCTGCGCTCCGATATCCGGCGGGGCGCCGCTCTGGCCGCT
AAGCAGGCCGGTCCGCTACCTCGCCTACGGCGAGGCCTCCGGGCTCGGGCGGATCCTCGCGGCGAGCGGGGTGGCGGCCG
GCCACGAGCCGGCCTTCACGTCGCACCTGGCGGCGACGCTGATGACCATGGCGCAGGGAGGCGACGGTGTCGCGTGGCTC
CCGGCGACGCTCGCGGAGGCGGCGATCGCGCGCGGCCTGCTCGTTCGGGCAGGTTCCCAGGAGCTGGACGTTCCGGTGGA
GATCCGGCTGTTCCGGGCGCGGGGGAGCCGCGGCGGCGCGGCCGAGGCCCTGTGGCAGCGCCTGCACGCGCCCGGACGTG
ACCGGCCCGATCAGCCCGTCGCCACCCGGGCGTAG

Upstream 100 bases:

>100_bases
TCCCGGTGCCGTAGCGCCGCTCGCACCCGGGCAGCCAATGCCGTTTCCGGCGCGCGCGATGCGCGAACGGCATCGGCCCG
TCCTGTCGGAGAGGCGCGCC

Downstream 100 bases:

>100_bases
CGGCCGTCGTAGCGGCCGGCCCGGATCTGCTCCAGAACCTCCGCCTCGCGGGCCGCCTGCGCACGCACAGCGTCGAGCAG
GGCCGCCGCGTCGCCGGGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDLDWMRDFLALAEHRTFSRAAEARNVTQPAFSRRIRALEEWVGTPLFLRSARGAGLTAAGARFRPGAEELLRGLDRARG
EARAAGARADASLAIAATHALSFTFFPSWIRQHAPFETLGALNLISDSMAACEAILLAGEVQLLLCHHRADLPTRLDDGR
CESIRVGADSLVPLCAPISGGAPLWPLSRPVRYLAYGEASGLGRILAASGVAAGHEPAFTSHLAATLMTMAQGGDGVAWL
PATLAEAAIARGLLVRAGSQELDVPVEIRLFRARGSRGGAAEALWQRLHAPGRDRPDQPVATRA

Sequences:

>Translated_304_residues
MDLDWMRDFLALAEHRTFSRAAEARNVTQPAFSRRIRALEEWVGTPLFLRSARGAGLTAAGARFRPGAEELLRGLDRARG
EARAAGARADASLAIAATHALSFTFFPSWIRQHAPFETLGALNLISDSMAACEAILLAGEVQLLLCHHRADLPTRLDDGR
CESIRVGADSLVPLCAPISGGAPLWPLSRPVRYLAYGEASGLGRILAASGVAAGHEPAFTSHLAATLMTMAQGGDGVAWL
PATLAEAAIARGLLVRAGSQELDVPVEIRLFRARGSRGGAAEALWQRLHAPGRDRPDQPVATRA
>Mature_304_residues
MDLDWMRDFLALAEHRTFSRAAEARNVTQPAFSRRIRALEEWVGTPLFLRSARGAGLTAAGARFRPGAEELLRGLDRARG
EARAAGARADASLAIAATHALSFTFFPSWIRQHAPFETLGALNLISDSMAACEAILLAGEVQLLLCHHRADLPTRLDDGR
CESIRVGADSLVPLCAPISGGAPLWPLSRPVRYLAYGEASGLGRILAASGVAAGHEPAFTSHLAATLMTMAQGGDGVAWL
PATLAEAAIARGLLVRAGSQELDVPVEIRLFRARGSRGGAAEALWQRLHAPGRDRPDQPVATRA

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=294, Percent_Identity=31.9727891156463, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI145693105, Length=106, Percent_Identity=36.7924528301887, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI157672245, Length=115, Percent_Identity=40.8695652173913, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788887, Length=108, Percent_Identity=36.1111111111111, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32388; Mature: 32388

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLDWMRDFLALAEHRTFSRAAEARNVTQPAFSRRIRALEEWVGTPLFLRSARGAGLTAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
GARFRPGAEELLRGLDRARGEARAAGARADASLAIAATHALSFTFFPSWIRQHAPFETLG
CCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHH
ALNLISDSMAACEAILLAGEVQLLLCHHRADLPTRLDDGRCESIRVGADSLVPLCAPISG
HHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCC
GAPLWPLSRPVRYLAYGEASGLGRILAASGVAAGHEPAFTSHLAATLMTMAQGGDGVAWL
CCCCCCCCCCHHHHEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEH
PATLAEAAIARGLLVRAGSQELDVPVEIRLFRARGSRGGAAEALWQRLHAPGRDRPDQPV
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCC
ATRA
CCCC
>Mature Secondary Structure
MDLDWMRDFLALAEHRTFSRAAEARNVTQPAFSRRIRALEEWVGTPLFLRSARGAGLTAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
GARFRPGAEELLRGLDRARGEARAAGARADASLAIAATHALSFTFFPSWIRQHAPFETLG
CCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHH
ALNLISDSMAACEAILLAGEVQLLLCHHRADLPTRLDDGRCESIRVGADSLVPLCAPISG
HHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCC
GAPLWPLSRPVRYLAYGEASGLGRILAASGVAAGHEPAFTSHLAATLMTMAQGGDGVAWL
CCCCCCCCCCHHHHEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEH
PATLAEAAIARGLLVRAGSQELDVPVEIRLFRARGSRGGAAEALWQRLHAPGRDRPDQPV
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCC
ATRA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]