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The map label for this gene is argK [C]

Identifier: 170749880

GI number: 170749880

Start: 3692228

End: 3693214

Strand: Direct

Name: argK [C]

Synonym: Mrad2831_3480

Alternate gene names: 170749880

Gene position: 3692228-3693214 (Clockwise)

Preceding gene: 170749878

Following gene: 170749881

Centisome position: 60.75

GC content: 71.53

Gene sequence:

>987_bases
ATGACGCCGTCCATCGACATCGAGAGTCTCCGGGAGCGCCTGCTGCGCGGCGACCGCGCCGCTCTGGCCCGCGCCATCAC
GCTGGCCGAGTCCAAGCGCGCCGATCACCGGGCGCTGGCGGCGAGCCTGATCGACTCGGTCCTGCCCGAGACCGGCCGGG
CGATCCGCGTCGGCATCACCGGCGTACCTGGCGTCGGCAAGTCGACCACCATCGACGCCCTCGGCTCGAACCTGACGGAG
GCCGGTCACAAGGTGGCGGTGCTCGCGGTCGACCCGTCGTCCTCGCGGACCGGCGGCTCGATCTTGGGCGACAAAACCCG
GATGGCGCGGCTGTCGCACGATCCCGGAGCCTTCATCCGTCCCTCCCCGTCCTCCGGCACGCTCGGCGGCGTCGCGGCCA
AGACCCGCGAGACCATGCTGCTCTGCGAGGCGGCGGGCTTCGACGTGATCCTCGTCGAGACGGTCGGCGTCGGCCAGTCG
GAAACGGCCGTGGCCGACCTCACCGACTTCTTCCTCGTGCTGATGCTGCCCGGGGCGGGCGACGAGTTGCAGGGCATCAA
GAAGGGCATTCTCGAACTCGCCGACATGATCGCCGTCAACAAGGCCGATGCGGGCGAGGCCGAGCAGCGCGCCAACGCGG
CGGCCTCGGAGTACCGGGCGGCGCTGCACATCCTGACTCCGGCCTCCGCCACCTGGACACCGCCGGTGGTCACGATCTCG
GGCTTCCACAACCTGCGGCTCGACGCCCTGTGGGCGAAGATCGTCGATCACCGGGAGAAGCTCACGGCGACCGGCGAGAT
CCAGGCGAAGCGCCGGACTCAGGACGTGAAGTGGATGTGGGCGCTGGTCGACGAGCGCCTGCACCAGCGTCTCGTCGGCT
CCCCGGAAGTTCGCCGCCGCACGGCCGAGGCCGAGGCCGGCGTCGCCCGGGGCGAGACCTCCCCGGCCGCCGGCGCGGCG
GCCATCGCCGAGTTGATCGGGCTCTGA

Upstream 100 bases:

>100_bases
GCACGGCTGGGCTTGTGGTGGGCGGGACACAGCCGGCCCATCCCCCGGCCCCGGTACTCTCCCCCTCGACGGCGGCCGTC
GCCGCAGCCATGAAGGGATC

Downstream 100 bases:

>100_bases
CCGTTCCGCGGCCGCGATCGCGGGGCGAGACGCACAATTTCGTGGCGGGCGGGGGCACAAACGCCGTCTCGCGCGTTCGG
TGGACGACGGCTTATCGAGC

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTPSIDIESLRERLLRGDRAALARAITLAESKRADHRALAASLIDSVLPETGRAIRVGITGVPGVGKSTTIDALGSNLTE
AGHKVAVLAVDPSSSRTGGSILGDKTRMARLSHDPGAFIRPSPSSGTLGGVAAKTRETMLLCEAAGFDVILVETVGVGQS
ETAVADLTDFFLVLMLPGAGDELQGIKKGILELADMIAVNKADAGEAEQRANAAASEYRAALHILTPASATWTPPVVTIS
GFHNLRLDALWAKIVDHREKLTATGEIQAKRRTQDVKWMWALVDERLHQRLVGSPEVRRRTAEAEAGVARGETSPAAGAA
AIAELIGL

Sequences:

>Translated_328_residues
MTPSIDIESLRERLLRGDRAALARAITLAESKRADHRALAASLIDSVLPETGRAIRVGITGVPGVGKSTTIDALGSNLTE
AGHKVAVLAVDPSSSRTGGSILGDKTRMARLSHDPGAFIRPSPSSGTLGGVAAKTRETMLLCEAAGFDVILVETVGVGQS
ETAVADLTDFFLVLMLPGAGDELQGIKKGILELADMIAVNKADAGEAEQRANAAASEYRAALHILTPASATWTPPVVTIS
GFHNLRLDALWAKIVDHREKLTATGEIQAKRRTQDVKWMWALVDERLHQRLVGSPEVRRRTAEAEAGVARGETSPAAGAA
AIAELIGL
>Mature_327_residues
TPSIDIESLRERLLRGDRAALARAITLAESKRADHRALAASLIDSVLPETGRAIRVGITGVPGVGKSTTIDALGSNLTEA
GHKVAVLAVDPSSSRTGGSILGDKTRMARLSHDPGAFIRPSPSSGTLGGVAAKTRETMLLCEAAGFDVILVETVGVGQSE
TAVADLTDFFLVLMLPGAGDELQGIKKGILELADMIAVNKADAGEAEQRANAAASEYRAALHILTPASATWTPPVVTISG
FHNLRLDALWAKIVDHREKLTATGEIQAKRRTQDVKWMWALVDERLHQRLVGSPEVRRRTAEAEAGVARGETSPAAGAAA
IAELIGL

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=323, Percent_Identity=47.6780185758514, Blast_Score=285, Evalue=3e-77,
Organism=Escherichia coli, GI1789285, Length=319, Percent_Identity=47.3354231974922, Blast_Score=293, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71994271, Length=328, Percent_Identity=40.5487804878049, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI71994275, Length=269, Percent_Identity=41.2639405204461, Blast_Score=226, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34494; Mature: 34363

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSIDIESLRERLLRGDRAALARAITLAESKRADHRALAASLIDSVLPETGRAIRVGIT
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
GVPGVGKSTTIDALGSNLTEAGHKVAVLAVDPSSSRTGGSILGDKTRMARLSHDPGAFIR
CCCCCCCCCCHHHHCCCHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
PSPSSGTLGGVAAKTRETMLLCEAAGFDVILVETVGVGQSETAVADLTDFFLVLMLPGAG
CCCCCCCCCCHHHHHHHHEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
DELQGIKKGILELADMIAVNKADAGEAEQRANAAASEYRAALHILTPASATWTPPVVTIS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEC
GFHNLRLDALWAKIVDHREKLTATGEIQAKRRTQDVKWMWALVDERLHQRLVGSPEVRRR
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TAEAEAGVARGETSPAAGAAAIAELIGL
HHHHHCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TPSIDIESLRERLLRGDRAALARAITLAESKRADHRALAASLIDSVLPETGRAIRVGIT
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
GVPGVGKSTTIDALGSNLTEAGHKVAVLAVDPSSSRTGGSILGDKTRMARLSHDPGAFIR
CCCCCCCCCCHHHHCCCHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
PSPSSGTLGGVAAKTRETMLLCEAAGFDVILVETVGVGQSETAVADLTDFFLVLMLPGAG
CCCCCCCCCCHHHHHHHHEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
DELQGIKKGILELADMIAVNKADAGEAEQRANAAASEYRAALHILTPASATWTPPVVTIS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEC
GFHNLRLDALWAKIVDHREKLTATGEIQAKRRTQDVKWMWALVDERLHQRLVGSPEVRRR
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TAEAEAGVARGETSPAAGAAAIAELIGL
HHHHHCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]